Result of FASTA (omim) for
pF1KB9874
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9874, 515 aa
1>>>pF1KB9874 515 - 515 aa - 515 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4206+/-0.00038; mu= 12.7880+/- 0.024
mean_var=88.2016+/-17.617, 0's: 0 Z-trim(115.0): 47 B-trim: 468 in 1/50
Lambda= 0.136564
statistics sampled from 25056 (25103) to 25056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.294), width: 16
Scan time: 7.840
The best scores are: opt bits E(85289)
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 3508 701.3 1.7e-201
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 1213 249.2 2.3e-65
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 949 197.1 8.6e-50
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 949 197.1 8.6e-50
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 945 196.3 1.5e-49
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 945 196.3 1.5e-49
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 945 196.3 1.5e-49
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 909 189.2 1.7e-47
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 909 189.2 1.7e-47
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 909 189.2 1.7e-47
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 909 189.2 1.7e-47
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 887 184.9 3.3e-46
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 887 184.9 3.3e-46
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 887 184.9 3.3e-46
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 832 174.1 6.7e-43
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 478 104.2 4.2e-22
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 478 104.2 4.2e-22
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 438 96.4 1.1e-19
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 438 96.4 1.1e-19
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 434 95.7 3.1e-19
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 432 95.3 3.7e-19
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 432 95.3 3.7e-19
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 432 95.3 3.7e-19
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 432 95.3 3.7e-19
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 412 91.3 4e-18
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 412 91.3 4e-18
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 409 90.7 6.3e-18
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 409 90.7 6.3e-18
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 409 90.7 6.3e-18
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 409 90.7 6.3e-18
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 408 90.5 6.8e-18
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 408 90.5 6.8e-18
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 391 87.1 8.2e-17
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 385 85.9 1.4e-16
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 385 85.9 1.4e-16
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 376 84.2 5.5e-16
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 376 84.2 5.5e-16
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 373 83.6 8.9e-16
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 326 74.3 5.1e-13
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 300 69.2 1.8e-11
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 298 68.8 3.1e-11
>>NP_110399 (OMIM: 611923) gap junction alpha-9 protein (515 aa)
initn: 3508 init1: 3508 opt: 3508 Z-score: 3738.5 bits: 701.3 E(85289): 1.7e-201
Smith-Waterman score: 3508; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 NSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 NSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 ELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPANCDWKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPANCDWKPR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 WLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIPNTADSLGGLSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 WLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIPNTADSLGGLSFE
430 440 450 460 470 480
490 500 510
pF1KB9 PGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI
:::::::::::::::::::::::::::::::::::
NP_110 PGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI
490 500 510
>>NP_115991 (OMIM: 611924) gap junction alpha-10 protein (543 aa)
initn: 1190 init1: 1190 opt: 1213 Z-score: 1294.5 bits: 249.2 E(85289): 2.3e-65
Smith-Waterman score: 1219; 47.7% identity (70.1% similar) in 461 aa overlap (1-453:1-414)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
:::::::: ::::: :::..:::::::::::::::: :::::::.::::.: :::.:::
NP_115 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
: :.:::.::::::::.::::.:::::::::::::::::::..:..::: :..::...:.
NP_115 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN
70 80 90 100 110 120
130 140 150 160 170
pF1KB9 VEFEMPRDRRRLEQELCQLEKRK-LNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY
.... ....:...:: .::..: ..:.::.: :: :::.::.::::.:::::::::.::
NP_115 PDLDL-EEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY
130 140 150 160 170
180 190 200 210 220 230
pF1KB9 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK
::...::.:: :::: .:::::::::::::.:::.:::.:::.::::::::::..::
NP_115 GFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 RGLWGKYKLKKEHNE----FHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTA
: :. : . . ..: :: .: .::. : .:: . : . : ..:. .
NP_115 RTLYKKSSSEGIEDETGPPFHLKK--YSVAQ-QCMICSSLPERISPLQAN--NQQQVIRV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 VYPSLNSSSVFQ-PNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDT
:. :....: :.: . :. ::..::
NP_115 NVPK--SKTMWQIPQPRQLEVDP------------------------------SNGKKDW
300 310 320
360 370 380 390 400 410
pF1KB9 HKIFGKELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPAN
. :. ...:: . : : . :..: .. .:.: :: . . : :
NP_115 SE---KDQHSGQLHVHSPCPWAGSAGNQHL-GQQS-DHSSFGLQNTMSQSWLGTTTAPRN
330 340 350 360 370
420 430 440 450 460 470
pF1KB9 CDWKPRWLRATWGSSTEHENRGSPPKGNLKGQFR--KGTVRTLPPSQGDSQSLDIPNTAD
: : . .:: .: . : : : .:... : .:..:
NP_115 C---PSFAVGTWEQSQDPEPSGEP-LTDLHSHCRDSEGSMRESGVWIDRSRPGSRKASFL
380 390 400 410 420 430
480 490 500 510
pF1KB9 SLGGLSFEPGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI
NP_115 SRLLSEKRHLHSDSGSSGSRNSSCLDFPHWENSPSPLPSVTGHRTSMVRQAALPIMELSQ
440 450 460 470 480 490
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 955 init1: 555 opt: 949 Z-score: 1014.9 bits: 197.1 E(85289): 8.6e-50
Smith-Waterman score: 949; 54.5% identity (83.1% similar) in 242 aa overlap (1-242:1-234)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..:: ::... :::.:::.:::.:::::.::::.::::::.:::: : :::.:::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
:.:::::.::::: ::.:.::.::::.:.:.:.::.:. .:. :....: : :.
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKERE------EEEQ
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
.. : : .. ... . . : ... . :.:: :::..:. ... ::::. :::.:::
XP_011 LKRESPSPKEPPQDNPSSRDDR--GRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
:.:.::..: :::: .:::.:::::::::..:: ..: ::.::.:::.:::.::.:.
XP_011 FELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL
:.
XP_011 GVTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPP
240 250 260 270 280 290
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 955 init1: 555 opt: 949 Z-score: 1014.9 bits: 197.1 E(85289): 8.6e-50
Smith-Waterman score: 949; 54.5% identity (83.1% similar) in 242 aa overlap (1-242:1-234)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..:: ::... :::.:::.:::.:::::.::::.::::::.:::: : :::.:::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
:.:::::.::::: ::.:.::.::::.:.:.:.::.:. .:. :....: : :.
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKERE------EEEQ
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
.. : : .. ... . . : ... . :.:: :::..:. ... ::::. :::.:::
NP_068 LKRESPSPKEPPQDNPSSRDDR--GRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
:.:.::..: :::: .:::.:::::::::..:: ..: ::.::.:::.:::.::.:.
NP_068 FELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 GLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSL
:.
NP_068 GVTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPP
240 250 260 270 280 290
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 997 init1: 559 opt: 945 Z-score: 1010.7 bits: 196.3 E(85289): 1.5e-49
Smith-Waterman score: 956; 39.8% identity (69.2% similar) in 425 aa overlap (1-413:1-398)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..::. ::::. :::.::..:::.:::::.:.::.::: ::.:::: :.:::.:::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVEL-E
:.:::::.::::: :: ::::.::::.:::.:.:::.. .: .::.:. .:. :: .
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVR-MEEKRKSREAE---ELGQ
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 EVEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY
.. . :. ... . .:. :.:::: ::. ::. ... ::::..:.:.::
XP_011 QAGTNGGPDQGSVKKSSGSKGTKKFR---LEGTLLRTYICHIIFKTLFEVGFIVGHYFLY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK
::.. ::..: ::::..:::::::::::::.::: :.:..:::::..:. :::.: :.
XP_011 GFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 RGLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPS
.: : ... .:. .:. ...: ..:... : :.:: :.. . .:
XP_011 SAL--KRPVEQPLGEI-PEKSLHSIA------VSSIQK---AKGYQLLEEEKIVSHYFP-
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 LNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFG
:. .. . .: : . . .: . .. .. :: . . . . : . .... :
XP_011 LTEVGMVETSP-----LPAKPFNQFEEKISTGPLGDLSRG--YQETLPSYAQVGAQEVEG
290 300 310 320 330
360 370 380 390 400
pF1KB9 K-----ELNGNQLMEKRETEGK----DSKRNYYSRGHR-SIPGVAIDGENNMRQSPQ-TV
. : .. ::.: . .... .:.. ::: .::.. :: . .
XP_011 EGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSK
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB9 FSLPANCDWKPRWLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIP
.:::
XP_011 QGLPAEKTPSLCPELTTDDARPLSRLSKASSRAR
400 410 420
>>NP_005258 (OMIM: 116200,600897,612474) gap junction al (433 aa)
initn: 997 init1: 559 opt: 945 Z-score: 1010.6 bits: 196.3 E(85289): 1.5e-49
Smith-Waterman score: 956; 39.8% identity (69.2% similar) in 425 aa overlap (1-413:1-398)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..::. ::::. :::.::..:::.:::::.:.::.::: ::.:::: :.:::.:::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVEL-E
:.:::::.::::: :: ::::.::::.:::.:.:::.. .: .::.:. .:. :: .
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVR-MEEKRKSREAE---ELGQ
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 EVEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY
.. . :. ... . .:. :.:::: ::. ::. ... ::::..:.:.::
NP_005 QAGTNGGPDQGSVKKSSGSKGTKKFR---LEGTLLRTYICHIIFKTLFEVGFIVGHYFLY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK
::.. ::..: ::::..:::::::::::::.::: :.:..:::::..:. :::.: :.
NP_005 GFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 RGLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPS
.: : ... .:. .:. ...: ..:... : :.:: :.. . .:
NP_005 SAL--KRPVEQPLGEI-PEKSLHSIA------VSSIQK---AKGYQLLEEEKIVSHYFP-
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 LNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFG
:. .. . .: : . . .: . .. .. :: . . . . : . .... :
NP_005 LTEVGMVETSP-----LPAKPFNQFEEKISTGPLGDLSRG--YQETLPSYAQVGAQEVEG
290 300 310 320 330
360 370 380 390 400
pF1KB9 K-----ELNGNQLMEKRETEGK----DSKRNYYSRGHR-SIPGVAIDGENNMRQSPQ-TV
. : .. ::.: . .... .:.. ::: .::.. :: . .
NP_005 EGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSK
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB9 FSLPANCDWKPRWLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIP
.:::
NP_005 QGLPAEKTPSLCPELTTDDARPLSRLSKASSRARSDDLTV
400 410 420 430
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 997 init1: 559 opt: 945 Z-score: 1010.6 bits: 196.3 E(85289): 1.5e-49
Smith-Waterman score: 956; 39.8% identity (69.2% similar) in 425 aa overlap (1-413:1-398)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..::. ::::. :::.::..:::.:::::.:.::.::: ::.:::: :.:::.:::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVEL-E
:.:::::.::::: :: ::::.::::.:::.:.:::.. .: .::.:. .:. :: .
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVR-MEEKRKSREAE---ELGQ
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 EVEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY
.. . :. ... . .:. :.:::: ::. ::. ... ::::..:.:.::
XP_011 QAGTNGGPDQGSVKKSSGSKGTKKFR---LEGTLLRTYICHIIFKTLFEVGFIVGHYFLY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK
::.. ::..: ::::..:::::::::::::.::: :.:..:::::..:. :::.: :.
XP_011 GFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 RGLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPS
.: : ... .:. .:. ...: ..:... : :.:: :.. . .:
XP_011 SAL--KRPVEQPLGEI-PEKSLHSIA------VSSIQK---AKGYQLLEEEKIVSHYFP-
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 LNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFG
:. .. . .: : . . .: . .. .. :: . . . . : . .... :
XP_011 LTEVGMVETSP-----LPAKPFNQFEEKISTGPLGDLSRG--YQETLPSYAQVGAQEVEG
290 300 310 320 330
360 370 380 390 400
pF1KB9 K-----ELNGNQLMEKRETEGK----DSKRNYYSRGHR-SIPGVAIDGENNMRQSPQ-TV
. : .. ::.: . .... .:.. ::: .::.. :: . .
XP_011 EGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSK
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB9 FSLPANCDWKPRWLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIP
.:::
XP_011 QGLPAEKTPSLCPELTTDDARPLSRLSKASSRARSDDLTV
400 410 420 430
>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 914 init1: 578 opt: 909 Z-score: 973.6 bits: 189.2 E(85289): 1.7e-47
Smith-Waterman score: 930; 45.9% identity (71.7% similar) in 314 aa overlap (1-312:1-295)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..::. ::::: :::..::.:::.::::::::::.:::. :.:::. : :.: :::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
:.::::::::::: :::::::.::::.:::::::::.. .:. :... : . .
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
.:.: .. :: :. . .. :.:::: ::: :. :...::::..:::..::
XP_005 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG
130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
. : : :. :::. ..:.:::::::..:..:: ..:..::.:.. :..:::.:::..
XP_005 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 GLWGKYKLKKEHNEFHANKAKQNVAKYQST--SANSLKRLPSAPDYNLLVEKQTHTAVYP
.: : .:..:: : . :.. .. ::.: .:. .
XP_005 -------------RF--VKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 SLNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIF
.... . : : ::
XP_005 PFSNNMASQQNTDNLVTEQVRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDK
290 300 310 320 330 340
>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 914 init1: 578 opt: 909 Z-score: 973.6 bits: 189.2 E(85289): 1.7e-47
Smith-Waterman score: 930; 45.9% identity (71.7% similar) in 314 aa overlap (1-312:1-295)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..::. ::::: :::..::.:::.::::::::::.:::. :.:::. : :.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
:.::::::::::: :::::::.::::.:::::::::.. .:. :... : . .
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
.:.: .. :: :. . .. :.:::: ::: :. :...::::..:::..::
NP_859 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG
130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
. : : :. :::. ..:.:::::::..:..:: ..:..::.:.. :..:::.:::..
NP_859 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 GLWGKYKLKKEHNEFHANKAKQNVAKYQST--SANSLKRLPSAPDYNLLVEKQTHTAVYP
.: : .:..:: : . :.. .. ::.: .:. .
NP_859 -------------RF--VKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 SLNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIF
.... . : : ::
NP_859 PFSNNMASQQNTDNLVTEQVRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDK
290 300 310 320 330 340
>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 914 init1: 578 opt: 909 Z-score: 973.6 bits: 189.2 E(85289): 1.7e-47
Smith-Waterman score: 930; 45.9% identity (71.7% similar) in 314 aa overlap (1-312:1-295)
10 20 30 40 50 60
pF1KB9 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG
::::..::. ::::: :::..::.:::.::::::::::.:::. :.:::. : :.: :::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE
:.::::::::::: :::::::.::::.:::::::::.. .:. :... : . .
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG
.:.: .. :: :. . .. :.:::: ::: :. :...::::..:::..::
XP_016 GSYEYPVAEK---AELSCWEEGN-GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG
130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR
. : : :. :::. ..:.:::::::..:..:: ..:..::.:.. :..:::.:::..
XP_016 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ
180 190 200 210 220 230
250 260 270 280 290
pF1KB9 GLWGKYKLKKEHNEFHANKAKQNVAKYQST--SANSLKRLPSAPDYNLLVEKQTHTAVYP
.: : .:..:: : . :.. .. ::.: .:. .
XP_016 -------------RF--VKPRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFN
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 SLNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIF
.... . : : ::
XP_016 PFSNNMASQQNTDNLVTEQVRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDK
290 300 310 320 330 340
515 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:56:37 2016 done: Fri Nov 4 19:56:38 2016
Total Scan time: 7.840 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]