FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9877, 546 aa 1>>>pF1KB9877 546 - 546 aa - 546 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.5219+/-0.00101; mu= -1.7860+/- 0.061 mean_var=349.0718+/-70.221, 0's: 0 Z-trim(115.3): 10 B-trim: 156 in 1/54 Lambda= 0.068646 statistics sampled from 15855 (15862) to 15855 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.487), width: 16 Scan time: 4.240 The best scores are: opt bits E(32554) CCDS59316.1 TCEB3CL2 gene_id:100506888|Hs108|chr18 ( 546) 3716 381.7 1.2e-105 CCDS11931.1 TCEB3C gene_id:162699|Hs108|chr18 ( 546) 3714 381.5 1.4e-105 CCDS11932.1 TCEB3B gene_id:51224|Hs108|chr18 ( 753) 1420 154.4 4.4e-37 CCDS239.2 TCEB3 gene_id:6924|Hs108|chr1 ( 798) 869 99.9 1.2e-20 >>CCDS59316.1 TCEB3CL2 gene_id:100506888|Hs108|chr18 (546 aa) initn: 3716 init1: 3716 opt: 3716 Z-score: 2010.0 bits: 381.7 E(32554): 1.2e-105 Smith-Waterman score: 3716; 99.6% identity (99.8% similar) in 546 aa overlap (1-546:1-546) 10 20 30 40 50 60 pF1KB9 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSRGASAQKSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSRGASAQKSPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQANYDLLSAFEAMTSQANPEAL :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VQESQSERLQAAVADSAGPKTVPSHVFSELWDPSEAWMQANYDLLSAFEAMTSQANPEAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SAPTLQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCLRVPRNNPDALGDVEGVPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SAPTLQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCLRVPRNNPDALGDVEGVPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SVLEPVLEGWTPDQPYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELYLRLR :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SALEPVLEGWTPDQPYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELYLRLR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 DAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEKSAGAADPGNGEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEKSAGAADPGNGEM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EPAPKPAGSSQAPSGLGDGDGGSVSGGGSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EPAPKPAGSSQAPSGLGDGDGGSVSGGGSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYK 490 500 510 520 530 540 pF1KB9 GRFSRR :::::: CCDS59 GRFSRR >>CCDS11931.1 TCEB3C gene_id:162699|Hs108|chr18 (546 aa) initn: 3714 init1: 3714 opt: 3714 Z-score: 2008.9 bits: 381.5 E(32554): 1.4e-105 Smith-Waterman score: 3714; 99.6% identity (99.8% similar) in 546 aa overlap (1-546:1-546) 10 20 30 40 50 60 pF1KB9 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSRGASAQKSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSRGASAQKSPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQANYDLLSAFEAMTSQANPEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQANYDLLSAFEAMTSQANPEAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SAPTLQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCLRVPRNNPDALGDVEGVPY :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SAPALQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCLRVPRNNPDALGDVEGVPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SVLEPVLEGWTPDQPYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELYLRLR :::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SVLEPVLEGWTPDQLYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELYLRLR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 DAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEKSAGAADPGNGEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEKSAGAADPGNGEM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EPAPKPAGSSQAPSGLGDGDGGSVSGGGSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EPAPKPAGSSQAPSGLGDGDGGSVSGGGSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYK 490 500 510 520 530 540 pF1KB9 GRFSRR :::::: CCDS11 GRFSRR >>CCDS11932.1 TCEB3B gene_id:51224|Hs108|chr18 (753 aa) initn: 3024 init1: 1420 opt: 1420 Z-score: 779.3 bits: 154.4 E(32554): 4.4e-37 Smith-Waterman score: 1871; 58.8% identity (62.0% similar) in 577 aa overlap (1-385:1-577) 10 20 30 40 50 60 pF1KB9 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ ::::::::.:: :::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR ::::::::::::::::::::::: : ::::::::::::::::::..:::::::::::::: CCDS11 HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM :::::::::::::::::::::::::: ::::::::: ::.:::::: .: ::::::: : CCDS11 SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSR--------- :::::::.::.::::::.::::::::: ::::::::.:: :::::::::: CCDS11 PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQ 190 200 210 220 230 240 pF1KB9 --------------GA-------------------------------------------- :: CCDS11 GDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEA 250 260 270 280 290 300 pF1KB9 ------------------------------------------------------------ CCDS11 PDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTS 310 320 330 340 350 360 pF1KB9 ------------------------------------------------------------ CCDS11 VSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGT 370 380 390 400 410 420 240 250 260 270 280 pF1KB9 -----SAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQANYDLLSAF ::.: :::::::::::::::::::::::::::::::::: :::::::::: :: CCDS11 RESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSDS 430 440 450 460 470 480 290 300 310 320 330 340 pF1KB9 EAMTSQANPEALSAPTLQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCLRVPRNN ..:::::.:::::.: ..::::::::::::::::::::::::::::::::::: .: ::: CCDS11 DSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCAQVLRNN 490 500 510 520 530 540 350 360 370 380 390 400 pF1KB9 PDALGDVEGVPYSVLEPVLEGWTPDQPYRTEKDNAALARETDELWRIHCLQDFKEEKPQE ::::.:: ::: ::::::::: ::: :: .::: :: CCDS11 PDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQE 550 560 570 580 590 600 410 420 430 440 450 460 pF1KB9 HESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEK CCDS11 NKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYDTSRRQEK 610 620 630 640 650 660 >-- initn: 776 init1: 574 opt: 750 Z-score: 420.7 bits: 88.1 E(32554): 4.1e-17 Smith-Waterman score: 750; 69.1% identity (82.9% similar) in 175 aa overlap (387-546:579-753) 360 370 380 390 400 410 pF1KB9 GVPYSVLEPVLEGWTPDQPYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELY :::::: : ::.::::::::::...::: : CCDS11 EVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQENKTWREQY 550 560 570 580 590 600 420 430 440 450 460 470 pF1KB9 LRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEKSAGAADPG ::: :: ::::::.::.::::: :.:.::..:::::.::::::::.::::::::: ::: CCDS11 LRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYDTSRRQEKSAGDADPE 610 620 630 640 650 660 480 490 500 510 520 pF1KB9 NGEMEPAPKPAGSSQAPSGLGDGDGGSVSGGG---------------SSNRHAAPADKTR :::..:: ::::::..::. ... :: :... :::.::::: ::: CCDS11 NGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCLSSSNEHAAPAAKTR 670 680 690 700 710 720 530 540 pF1KB9 KQAAKKVAPLMAKAIRDYKGRFSRR ::::::::::::::::::: ::::: CCDS11 KQAAKKVAPLMAKAIRDYKRRFSRR 730 740 750 >>CCDS239.2 TCEB3 gene_id:6924|Hs108|chr1 (798 aa) initn: 1420 init1: 718 opt: 869 Z-score: 484.0 bits: 99.9 E(32554): 1.2e-20 Smith-Waterman score: 962; 38.8% identity (64.6% similar) in 492 aa overlap (82-546:314-798) 60 70 80 90 100 110 pF1KB9 TVKRLRKHQHVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWG :. : . . ..: : .:... CCDS23 KSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKK----C 290 300 310 320 330 120 130 140 150 160 pF1KB9 FPENATAPRSPSHSPEHRRTAR----RTPPGQQRPHPRSPSRE--PRAERKRPRMAPADS .: . .: . ..:.:: . .. : . . . . :....: . CCDS23 LPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPE 340 350 360 370 380 390 170 180 190 200 210 220 pF1KB9 GPHRDPPTRTAPLPMPEGPEPAVPGE--QPGRG-HAHAAQGGPLLGQGCQGQPQGEAVGS : . : . .:. : . : :: . ... . : . . .. :.:. CCDS23 GKVKTNLDRKSLGSLPKVEETDMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGD 400 410 420 430 440 450 230 240 250 260 270 pF1KB9 HS--KGHKSSRGA---SAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAW .. :. ..: : :.:: : :....::. :::: : . ::. :. : : CCDS23 KGLKKNDSKSTGKNLDSVQKLPKVNKTKSEK--PAGADLAKLRKVPD-VLPVLPDLPLPA 460 470 480 490 500 510 280 290 300 310 320 330 pF1KB9 MQANYDLLSAFEAMTS-QANPEALSAPTLQEEAAFPGRRVNAKMPVYSGSRPACQLQVPT .:::: : ..: ..: : . .:.:.: .:::.: :::.:.:: :::::. : .. : CCDS23 IQANYRPLPSLELISSFQPKRKAFSSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMT 520 530 540 550 560 570 340 350 360 370 380 390 pF1KB9 LRQQCLRVPRNNPDALGDVEGVPYSVLEPVLEGWTPDQPYRTEKDNAALARETDELWRIH :.:::.:: .:: :.. .: :::::::::::: :::: :: :. : .: .:::.::..: CCDS23 LHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVH 580 590 600 610 620 630 400 410 420 430 440 450 pF1KB9 CLQDFKEEKPQEHESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVA : .:::::.:.:.:::::.::::.:::::::::.: .:. :. :::.:::.:: :::: CCDS23 CHRDFKEERPEEYESWREMYLRLQDAREQRLRVLTKNIQFAHANKPKGRQAKMAFVNSVA 640 650 660 670 680 690 460 470 480 490 500 510 pF1KB9 KTPYDASRRQEK--SAGAADPGNGEMEPAPKPAGSSQAP-SGLG---DGDGGSVSGGGSS : : :. ::::: ..::: : . ...::: : :::.: :... . . . .: ..: CCDS23 KPPRDVRRRQEKFGTGGAAVPEKIKIKPAPYPMGSSHASASSISFNPSPEEPAYDGPSTS 700 710 720 730 740 750 520 530 540 pF1KB9 NRHAAPADKT------RKQAAKKVAPLMAKAIRDYKGRFSRR . : ::. .. :: ..::.::.:::.:. .:.::::: CCDS23 SAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR 760 770 780 790 546 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:57:45 2016 done: Fri Nov 4 19:57:46 2016 Total Scan time: 4.240 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]