Result of FASTA (ccds) for
pF1KB9878
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9878, 575 aa
1>>>pF1KB9878 575 - 575 aa - 575 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2063+/-0.000843; mu= 11.4262+/- 0.051
mean_var=150.8094+/-30.310, 0's: 0 Z-trim(112.6): 81 B-trim: 174 in 2/50
Lambda= 0.104438
statistics sampled from 13287 (13373) to 13287 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.411), width: 16
Scan time: 3.870
The best scores are: opt bits E(32554)
CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 ( 575) 3879 596.3 3.4e-170
CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 ( 499) 2392 372.2 8.5e-103
CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 ( 495) 2315 360.6 2.6e-99
CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 ( 653) 2243 349.8 6e-96
CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 ( 456) 1958 306.8 3.9e-83
CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 ( 511) 1927 302.1 1.1e-81
CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 ( 356) 1456 231.0 1.9e-60
CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 ( 613) 990 161.0 3.9e-39
CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 ( 529) 904 148.0 2.8e-35
CCDS14314.1 KCND1 gene_id:3750|Hs108|chrX ( 647) 846 139.3 1.4e-32
CCDS13418.1 KCNB1 gene_id:3745|Hs108|chr20 ( 858) 782 129.8 1.4e-29
CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8 ( 911) 777 129.1 2.4e-29
CCDS1692.1 KCNS3 gene_id:3790|Hs108|chr2 ( 491) 674 113.3 7.1e-25
CCDS844.1 KCND3 gene_id:3752|Hs108|chr1 ( 636) 666 112.2 2e-24
CCDS843.1 KCND3 gene_id:3752|Hs108|chr1 ( 655) 666 112.2 2e-24
CCDS1809.1 KCNG3 gene_id:170850|Hs108|chr2 ( 436) 661 111.3 2.5e-24
CCDS5776.1 KCND2 gene_id:3751|Hs108|chr7 ( 630) 660 111.3 3.7e-24
CCDS1676.1 KCNF1 gene_id:3754|Hs108|chr2 ( 494) 649 109.6 9.6e-24
CCDS7827.1 KCNC1 gene_id:3746|Hs108|chr11 ( 511) 628 106.4 8.9e-23
CCDS13342.1 KCNS1 gene_id:3787|Hs108|chr20 ( 526) 628 106.4 9.1e-23
CCDS44547.1 KCNC1 gene_id:3746|Hs108|chr11 ( 585) 628 106.5 9.8e-23
CCDS6314.1 KCNV1 gene_id:27012|Hs108|chr8 ( 500) 616 104.6 3.1e-22
CCDS9006.1 KCNC2 gene_id:3747|Hs108|chr12 ( 558) 613 104.2 4.5e-22
CCDS58255.1 KCNC2 gene_id:3747|Hs108|chr12 ( 583) 613 104.2 4.7e-22
CCDS9005.1 KCNC2 gene_id:3747|Hs108|chr12 ( 613) 613 104.2 4.9e-22
CCDS58257.1 KCNC2 gene_id:3747|Hs108|chr12 ( 618) 613 104.2 4.9e-22
CCDS58256.1 KCNC2 gene_id:3747|Hs108|chr12 ( 629) 613 104.2 5e-22
CCDS9007.1 KCNC2 gene_id:3747|Hs108|chr12 ( 638) 613 104.2 5e-22
CCDS13436.1 KCNG1 gene_id:3755|Hs108|chr20 ( 513) 605 102.9 9.8e-22
CCDS12793.1 KCNC3 gene_id:3748|Hs108|chr19 ( 757) 607 103.4 1.1e-21
CCDS44193.1 KCNC4 gene_id:3749|Hs108|chr1 ( 626) 605 103.0 1.1e-21
CCDS821.1 KCNC4 gene_id:3749|Hs108|chr1 ( 635) 605 103.0 1.2e-21
CCDS6279.1 KCNS2 gene_id:3788|Hs108|chr8 ( 477) 594 101.3 2.9e-21
CCDS42674.1 KCNG3 gene_id:170850|Hs108|chr2 ( 425) 577 98.7 1.6e-20
CCDS12019.1 KCNG2 gene_id:26251|Hs108|chr18 ( 466) 565 96.9 6e-20
CCDS6447.1 KCNV2 gene_id:169522|Hs108|chr9 ( 545) 553 95.1 2.3e-19
CCDS10945.1 KCNG4 gene_id:93107|Hs108|chr16 ( 519) 544 93.8 5.8e-19
>>CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 (575 aa)
initn: 3879 init1: 3879 opt: 3879 Z-score: 3169.0 bits: 596.3 E(32554): 3.4e-170
Smith-Waterman score: 3879; 100.0% identity (100.0% similar) in 575 aa overlap (1-575:1-575)
10 20 30 40 50 60
pF1KB9 MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
490 500 510 520 530 540
550 560 570
pF1KB9 AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
:::::::::::::::::::::::::::::::::::
CCDS82 AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
550 560 570
>>CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 (499 aa)
initn: 2293 init1: 984 opt: 2392 Z-score: 1959.0 bits: 372.2 E(32554): 8.5e-103
Smith-Waterman score: 2392; 74.7% identity (85.6% similar) in 514 aa overlap (66-575:3-499)
40 50 60 70 80 90
pF1KB9 VNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPA
:: : : .. : : :.:
CCDS82 MTVATGDPADEAAALPGHPQDTYDP-------
10 20
100 110 120 130 140 150
pF1KB9 AGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPS
....:: ::::::::::::::::::: :::::::::::.::::::::::::::::::::
CCDS82 EADHECC-ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPS
30 40 50 60 70 80
160 170 180 190 200 210
pF1KB9 FDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRD
:::::::::::::.:::::::.::::::::::.::::::: ::::::...:::::::. .
CCDS82 FDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENE
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB9 FQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFE
::::::::::::::::::: ::::::.::::::: ::::::: ::::.. : .:.
CCDS82 FQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-DMHGSGVTFH
150 160 170 180 190 200
280 290 300 310 320 330
pF1KB9 AAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVA
. .::: : . ..::.::::.::::::::::::.::::::::::: : ::::.:::::
CCDS82 TYSNSTIGYQQ-STSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVA
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB9 IIPYFITLGTELAERQGN---GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLK
::::::::::::::. . :::::::::::::::::::::::::::::::::::::::
CCDS82 IIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLK
270 280 290 300 310 320
400 410 420 430 440 450
pF1KB9 ASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHP
::::::::::::::::::::::::::::::. : : :::::::::::.::::::::: :
CCDS82 ASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVP
330 340 350 360 370 380
460 470 480 490 500 510
pF1KB9 VTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSA
.:::::::::::::::::::::::::::::::::::::::::::.::..: :: .. ::
CCDS82 TTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSP
390 400 410 420 430 440
520 530 540 550 560 570
pF1KB9 EELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGN-STATCTTNNNPNSCVNIKKI
. :.:.:: ::.:::.:: :.:: .:.: . :. : .::.:: :. . ::: :.
CCDS82 D-LKKSRSASTISKSDYMEIQEG-VNNS---NEDFREENLKTANCTLANT--NYVNITKM
450 460 470 480 490
pF1KB9 FTDV
.:::
CCDS82 LTDV
>>CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 (495 aa)
initn: 2345 init1: 997 opt: 2315 Z-score: 1896.3 bits: 360.6 E(32554): 2.6e-99
Smith-Waterman score: 2367; 72.2% identity (85.2% similar) in 528 aa overlap (53-575:1-495)
30 40 50 60 70 80
pF1KB9 PQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGG
:::. :... : .: : :: :
CCDS85 MTVMSGENVDEASAAPG---HPQDG-----
10 20
90 100 110 120 130 140
pF1KB9 CDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDP
: : ...:: ::::::::::::::::::: :::.::::.::.:::::::
CCDS85 --SY----PRQADHDDHECC-ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDP
30 40 50 60 70
150 160 170 180 190 200
pF1KB9 LRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEG
::::::::::::::::::::::::::.:::::::.:.:::::.::.::::::::::::::
CCDS85 LRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEG
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB9 FLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE
:..:::::::....:::::::::::::::::: ::::::.::::::::::::::::..:.
CCDS85 FIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDD
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB9 KDYPASTSQ-DSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKA
::. ... . :. . :: . :.::::.:::::::::::::.:::::::::.
CCDS85 KDFTGTVHRIDNTTVIYNS--------NIFTDPFFIVETLCIIWFSFELVVRFFACPSKT
200 210 220 230 240
330 340 350 360 370
pF1KB9 TFSRNIMNLIDIVAIIPYFITLGTELAERQGN--GQQAMSLAILRVIRLVRVFRIFKLSR
: .::::.::::::::::::::::.::..:: :.:: :::::::::::::::::::::
CCDS85 DFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSR
250 260 270 280 290 300
380 390 400 410 420 430
pF1KB9 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAV
::::::::::::::::::::::::::::::::::::::::::.. : ::::::::::::
CCDS85 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAV
310 320 330 340 350 360
440 450 460 470 480 490
pF1KB9 VTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQY
:.:::::::::.:::::::::::::::::::::::::::::::::::::::::::::.:
CCDS85 VSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQL
370 380 390 400 410 420
500 510 520 530 540 550
pF1KB9 MHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSA--FPQTPFKTGNSTATCT
.::.: .:.:... : ::.::.:::::: ::: ::.: . :. ..:.: ::
CCDS85 LHVSS-PNLASDSDLSR--RSSSTMSKSEYMEIEED-MNNSIAHYRQVNIRTAN----CT
430 440 450 460 470
560 570
pF1KB9 TNNNPNSCVNIKKIFTDV
: : ..::: .:..:::
CCDS85 TAN--QNCVNKSKLLTDV
480 490
>>CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 (653 aa)
initn: 1907 init1: 868 opt: 2243 Z-score: 1836.1 bits: 349.8 E(32554): 6e-96
Smith-Waterman score: 2252; 63.4% identity (79.7% similar) in 576 aa overlap (15-575:90-653)
10 20 30 40
pF1KB9 MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPA
: ...:: : .: :. : .:
CCDS41 GSHHHHQSRGACTSHDPQSSRGSRRRRRQRSEKKKAH--YRQSSFPHCSDLMPSG-SEEK
60 70 80 90 100 110
50 60 70 80 90
pF1KB9 AGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQ-----
::: . :. : : . : . : :. . :: . ..: .
CCDS41 ILRELSEEEE----DEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYS
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 DCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAI
::: ::::::.::::::::.::: ::::::::::..: .:::::::::::::::::::::
CCDS41 DCC-ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAI
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB9 LYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEE-RPLPRRDFQR
:::::::::..::::::.:::.::..::::::::. ::::::::.:::: : ::. .:..
CCDS41 LYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKK
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 QVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAG
:.::::::::::.::::::::::::::::::::::::::::::..: . : . .
CCDS41 QIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLL
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB9 NSTSGSR---AGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVA
:.::. . .: . :.::::.:::.::.:::::..:: :::::.: : .::::.::::.
CCDS41 NDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVS
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB9 IIPYFITLGTELAERQGNG----QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTL
:.::::::::.::..::.: :::::.::::.:::::::::::::::::::::::.::
CCDS41 ILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTL
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB9 KASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMH
.::::::::::::::::::::::::::::::.::. :.:::::::::::::::::::::.
CCDS41 RASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMK
480 490 500 510 520 530
460 470 480 490 500 510
pF1KB9 PVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVG-SCQHLSS
:.:.:::::::::::::::::::::::::::::::::::::.:::.: . . :: .: :
CCDS41 PITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPS
540 550 560 570 580 590
520 530 540 550 560
pF1KB9 SA-EELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIK
. ...:.. :.: .::::. .::: ...: . :.. . : .:: : : :
CCDS41 NLLKKFRSSTSSSLGDKSEYLEMEEG-VKESLCAKEEKCQGKGDDSETDKNN---CSNAK
600 610 620 630 640
570
pF1KB9 KIFTDV
. :::
CCDS41 AVETDV
650
>>CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 (456 aa)
initn: 1950 init1: 1178 opt: 1958 Z-score: 1606.1 bits: 306.8 E(32554): 3.9e-83
Smith-Waterman score: 1958; 69.1% identity (83.8% similar) in 433 aa overlap (87-512:2-428)
60 70 80 90 100 110
pF1KB9 PGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFE
:: : : : :: ::.:.:..:::::
CCDS12 MEPRCP--PPCG---CC-ERLVLNVAGLRFE
10 20
120 130 140 150 160 170
pF1KB9 TQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVP
:. .:: .::.:::::: :: :..: : ::::::.::::::.:::::::::.:::..::
CCDS12 TRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVP
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB9 IDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGI
.:.: ::. :: :: :. ..::::: ::::::: : ::.:::::.:::: :: .
CCDS12 LDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVL
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB9 AIVSVLVILISIVIFCLETLPEFRDEKD---YPASTSQDSFEAAGNSTSGSRAGASS--F
:.:::::::.:::.:::::::.:::..: :... : : :..: .. :
CCDS12 AVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPF
150 160 170 180 190 200
300 310 320 330 340 350
pF1KB9 SDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ
.::::::::::: :::::::::...::::: : .:.:::::.:::.:::..::::::...
CCDS12 NDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQR
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB9 GNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL
: ::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.:
CCDS12 GVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVL
270 280 290 300 310 320
420 430 440 450 460 470
pF1KB9 FSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLT
:::::::::.: : :.:::..:::::::::::::::: :::.::::::::::::::::
CCDS12 FSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLT
330 340 350 360 370 380
480 490 500 510 520
pF1KB9 IALPVPVIVSNFNYFYHRETEGEEQSQYMHVG--SCQHLSSSAEELRKARSNSTLSKSEY
:.::::::::::.::::::::::: ... :: : : ..:
CCDS12 ISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLW
390 400 410 420 430 440
530 540 550 560 570
pF1KB9 MVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
CCDS12 APPGKHLVTEV
450
>>CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 (511 aa)
initn: 1924 init1: 836 opt: 1927 Z-score: 1580.2 bits: 302.1 E(32554): 1.1e-81
Smith-Waterman score: 1927; 70.8% identity (87.3% similar) in 408 aa overlap (90-496:73-473)
60 70 80 90 100 110
pF1KB9 HLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQL
::. : . ..::.:::.::::::::
CCDS82 GSSFSNGKILISESTNHETAFSKLPGDYADPPG-PEPVVLNEGNQRVIINIAGLRFETQL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 KTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDI
.:: ::::::::: ..::..:: .::::::::::::::.:::::::::.::::.::::::
CCDS82 RTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 FSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIV
:..:: ::.:: :::..:::::::... : :: :..:: ::::::::::. ::..:.:
CCDS82 FADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 SVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVE
::::..:::.:::::::::::.... . . . . : . . . :.::::.::
CCDS82 SVLVVVISITIFCLETLPEFREDRELKVVRDPNL------NMSKTVLSQTMFTDPFFMVE
230 240 250 260 270
300 310 320 330 340 350
pF1KB9 TLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELA-ERQGNGQQAM
. ::.::.:::..:: .::::. : :::::.:::..::::: :: :::. : . ..:: :
CCDS82 STCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNM
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 SLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB9 AEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPV
::.:.: : ::::::.:::::::::::::::: :.: ::::::.::::::::::::::::
CCDS82 AEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPV
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB9 IVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMN
::::::::::::::.::.
CCDS82 IVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKSRK
460 470 480 490 500 510
>>CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 (356 aa)
initn: 1394 init1: 974 opt: 1456 Z-score: 1198.8 bits: 231.0 E(32554): 1.9e-60
Smith-Waterman score: 1456; 70.7% identity (82.9% similar) in 328 aa overlap (66-390:3-318)
40 50 60 70 80 90
pF1KB9 VNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPA
:: : : .. : : :.:
CCDS55 MTVATGDPADEAAALPGHPQDTYDP-------
10 20
100 110 120 130 140 150
pF1KB9 AGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPS
....:: ::::::::::::::::::: :::::::::::.::::::::::::::::::::
CCDS55 EADHECC-ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPS
30 40 50 60 70 80
160 170 180 190 200 210
pF1KB9 FDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRD
:::::::::::::.:::::::.::::::::::.::::::: ::::::...:::::::. .
CCDS55 FDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENE
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB9 FQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFE
::::::::::::::::::: ::::::.::::::: ::::::: ::::.. : .:.
CCDS55 FQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-DMHGSGVTFH
150 160 170 180 190 200
280 290 300 310 320 330
pF1KB9 AAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVA
. .::: : . ..::.::::.::::::::::::.::::::::::: : ::::.:::::
CCDS55 TYSNSTIGYQQ-STSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVA
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB9 IIPYFITLGTELAERQGN---GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLK
::::::::::::::. . ::::::::::::::: : : .. .. ..: : :. .
CCDS55 IIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLER--RPLQSQKSKRGRQHLNTSHD
270 280 290 300 310 320
400 410 420 430 440 450
pF1KB9 ASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHP
CCDS55 CTLGINLVAGMTVQWTRASGPDDRQTPAVTTLHRMY
330 340 350
>>CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 (613 aa)
initn: 2147 init1: 930 opt: 990 Z-score: 816.1 bits: 161.0 E(32554): 3.9e-39
Smith-Waterman score: 2148; 68.3% identity (79.1% similar) in 511 aa overlap (13-495:37-531)
10 20 30 40
pF1KB9 MDERLSLLRSPPPPSARHRAHPPQRPASSG-GAHTLVNHGYA
::.: . :..:: .: ::. .. :
CCDS85 PLENGGAMTVRGGDEARAGCGQATGGELQCPPTA-GLSDGPKEPAPKGRGAQRDADSGV-
10 20 30 40 50 60
50 60 70 80 90
pF1KB9 EPAAGRELPP--DMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSL-----P
: ::: : : : : : :. ::. :. : :.:
CCDS85 -----RPLPPLPDPGVRPLPPLPE-ELPRPRRPPPE--------DEEEEGDPGLGTVEDQ
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 AAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRP
: : . .:: :::::::::::: :: :::.:::::: .:.:::::::::::::::::
CCDS85 ALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 SFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRR
:::.::::::::::.:::::: .:.:..::::::::.::::.:::::::..:::.::::
CCDS85 SFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRN
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB9 DFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKD---YPASTSQ
.:::::::.:::::::: ::.:::::::::::::. ::::::::::::.. .: . :
CCDS85 EFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQ
240 250 260 270 280 290
280 290 300 310 320
pF1KB9 DSFEAAGNSTSGSRAGAS----------SFSDPFFVVETLCIIWFSFELLVRFFACPSKA
: : . :: : : ...::::.::: :.:::.::::::::::::::
CCDS85 PPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKA
300 310 320 330 340 350
330 340 350 360 370
pF1KB9 TFSRNIMNLIDIVAIIPYFITLGTELAERQG-------NGQQAMSLAILRVIRLVRVFRI
:::::::.::.:::.::::::::::::.: ::::::::::::::::::::::
CCDS85 GFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRI
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB9 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDA
::::::::::::::.::.::::::::::::::::::::::::::::::. . :::::::
CCDS85 FKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDA
420 430 440 450 460 470
440 450 460 470 480 490
pF1KB9 FWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGE
::::::::::::::::.:.:.::::::::::::::::::::::::::::::::::::. :
CCDS85 FWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHE
480 490 500 510 520 530
500 510 520 530 540 550
pF1KB9 EQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTA
:
CCDS85 EPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKA
540 550 560 570 580 590
>>CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 (529 aa)
initn: 1828 init1: 894 opt: 904 Z-score: 747.0 bits: 148.0 E(32554): 2.8e-35
Smith-Waterman score: 2109; 68.9% identity (78.9% similar) in 508 aa overlap (63-529:19-501)
40 50 60 70 80 90
pF1KB9 HTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPS
: : :.: : :: ::::
CCDS85 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGG--GGGC---------
10 20 30
100 110 120 130 140 150
pF1KB9 LPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRN
: .::.:::::::::::::.:: ::.:::::: ::.:.:::::::::::::
CCDS85 --------CSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRN
40 50 60 70 80
160 170 180 190 200
pF1KB9 RPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLRE---EER
::::::::::::::::.:::::::.::: :::::::::.::. :::::: : : .:.
CCDS85 RPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEK
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB9 PLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE-------
::: . ::::::::::::::::::::::::::::::::::::::::::.:: .
CCDS85 PLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNG
150 160 170 180 190 200
270 280 290 300
pF1KB9 ---KDYPAST-SQ-------DSFE----------AAGNSTSGSRAGASSFSDPFFVVETL
. :.: :: ::. ..:.:.: : :.: :.::::.::::
CCDS85 GVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETL
210 220 230 240 250 260
310 320 330 340 350
pF1KB9 CIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ------G---
::.::.::::::: ::::: .: :::::.::.:::.::::::::::...: :
CCDS85 CIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGG
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB9 -NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL
::::::::::::::::::::::::::::::::::::.::.:::::::::::::::::::
CCDS85 QNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVIL
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB9 FSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLT
:::::::::::: : : :::::::::::::::::::::.:.:.::::::::::::::::
CCDS85 FSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLT
390 400 410 420 430 440
480 490 500 510 520 530
pF1KB9 IALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMV
::::::::::::::::::::: :::.:: :: .: .. : .:: ... :.: ..
CCDS85 IALPVPVIVSNFNYFYHRETEQEEQGQYTHV-TC---GQPAPDLRA--TDNGLGKPDFPE
450 460 470 480 490 500
540 550 560 570
pF1KB9 IEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
CCDS85 ANRERRPSYLPTPHRAYAEKRMLTEV
510 520
>>CCDS14314.1 KCND1 gene_id:3750|Hs108|chrX (647 aa)
initn: 823 init1: 506 opt: 846 Z-score: 698.6 bits: 139.3 E(32554): 1.4e-32
Smith-Waterman score: 945; 38.6% identity (65.7% similar) in 492 aa overlap (87-559:25-470)
60 70 80 90 100 110
pF1KB9 PGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERV-VINISGLRF
.::: :: : . :..: :.:.:: ::
CCDS14 MAAGLATWLPFARAAAVGWLPLAQQPLP---PAPGVKASRGDEVLVVNVSGRRF
10 20 30 40 50
120 130 140 150 160 170
pF1KB9 ETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNV
:: .:: ..:.::::. .... ..: .::::::. : .: .:..: :.. : .
CCDS14 ETWKNTLDRYPDTLLGSSEKEF-FYDADSGEYFFDRDPDMFRHVLNFYRTG-RLHCPRQE
60 70 80 90 100
180 190 200 210
pF1KB9 PIDIFSEEIRFYQL-----GEEAMEKFR----EDEGFLREEER-------P-LPRRDFQR
:. :.::. :: : :. .:..: :. : :.:. : :: . :
CCDS14 CIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPALPAGSSLR
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 Q-VWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAA
: .: :: :..: : . :. . : .:.. .::.: : .:. ..: :
CCDS14 QRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIP-CR------GSARRSSRE--
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB9 GNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAII
. : : : . :: ..: :.. :. : :.:.:: ::. : :..:.:::.:::.
CCDS14 --QPCGER-----FPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAIL
230 240 250 260 270
340 350 360 370 380 390
pF1KB9 PYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE
::.: : :. . : . . ... :::. :::::::.::::.::.::: :::. :
CCDS14 PYYIGL---LVPK--NDDVSGAFVTLRVF---RVFRIFKFSRHSQGLRILGYTLKSCASE
280 290 300 310 320
400 410 420 430 440 450
pF1KB9 LGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGG
::.:.: : ...:.:......:: ..:.::: :::...:::::.::::: : ::.:
CCDS14 LGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAG
330 340 350 360 370 380
460 470 480 490 500 510
pF1KB9 KIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRK
:: ::.:...:::.::::::::::::. .::.. ..... ..: .:. ..:
CCDS14 KIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKV----RLA----RIRL
390 400 410 420 430
520 530 540 550 560 570
pF1KB9 ARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
:.:..: . .: ..::.. :. .:. : :. :
CCDS14 AKSGTTNAFLQYK--QNGGLEDSG-------SGEEQALCVRNRSAFEQQHHHLLHCLEKT
440 450 460 470 480
CCDS14 TCHEFTDELTFSEALGAVSPGGRTSRSTSVSSQPVGPGSLLSSCCPRRAKRRAIRLANST
490 500 510 520 530 540
575 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:36:38 2016 done: Sun Nov 6 09:36:39 2016
Total Scan time: 3.870 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]