Result of FASTA (omim) for
pF1KB9879
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9879, 584 aa
1>>>pF1KB9879 584 - 584 aa - 584 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0394+/-0.00035; mu= -0.8532+/- 0.022
mean_var=282.3594+/-58.240, 0's: 0 Z-trim(123.8): 12 B-trim: 2359 in 1/54
Lambda= 0.076326
statistics sampled from 44181 (44194) to 44181 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.518), width: 16
Scan time: 10.120
The best scores are: opt bits E(85289)
NP_056464 (OMIM: 615331) interferon regulatory fac ( 584) 4068 461.2 4.4e-129
NP_892017 (OMIM: 615332) interferon regulatory fac ( 587) 962 119.1 4e-26
NP_001070865 (OMIM: 615332) interferon regulatory ( 571) 648 84.6 1e-15
NP_078772 (OMIM: 611720) interferon regulatory fac ( 796) 616 81.1 1.5e-14
>>NP_056464 (OMIM: 615331) interferon regulatory factor (584 aa)
initn: 4068 init1: 4068 opt: 4068 Z-score: 2438.5 bits: 461.2 E(85289): 4.4e-129
Smith-Waterman score: 4068; 100.0% identity (100.0% similar) in 584 aa overlap (1-584:1-584)
10 20 30 40 50 60
pF1KB9 MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGVSGQDRYDRATSSGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSGLGSRGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSGLGSRGLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 LREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAPAEALPQQYPEPAPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 ALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQRHWVAPGGPYSAETPGVP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 SPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SPIAALKNVAEALGHSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARNGEAEVSPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 AGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AGAEAVSGGGSGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGP
490 500 510 520 530 540
550 560 570 580
pF1KB9 AGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP
::::::::::::::::::::::::::::::::::::::::::::
NP_056 AGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP
550 560 570 580
>>NP_892017 (OMIM: 615332) interferon regulatory factor (587 aa)
initn: 1073 init1: 566 opt: 962 Z-score: 590.0 bits: 119.1 E(85289): 4e-26
Smith-Waterman score: 1025; 38.0% identity (56.1% similar) in 629 aa overlap (1-583:5-586)
10 20 30 40 50
pF1KB9 MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLK
.: . ::::: :::::::.:::::.:::.: :::::::.:::::.:..:..:::::
NP_892 MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 RSH-VLPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQA--QPQPSGTGGGVSGQDRYD
:.: .:::::: : : :.:::. : : . : : . :: . :
NP_892 RAHGCFPEGRSP-PGAA--------ASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAP
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 RATSSGRLPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSG
.: : :: . : . ::.. .: . .: :.. : .:: . . : .
NP_892 QALE--RYPLAAAAER---PPRLGSDFGSSRPAAS------LAQPPTPQPPPVNGILVPN
120 130 140 150 160
180 190 200 210 220 230
pF1KB9 LGSRGLTLAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQL
: : : :. : . .:. : : : : : :.
NP_892 -GFSKLEEPPELNRQSP---------NPRRGHAVPPTLVPLMNGSATPL---PTALG---
170 180 190 200
240 250 260 270 280 290
pF1KB9 LALSACAPFNVRFKKDHGLVGRVFAFD--ATARPPGYEFELKLFTEYPCGSGNVYAGVLA
:. : : . . . .: . : : :: . . : .. :
NP_892 LGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAA--------A
210 220 230 240 250
300 310 320 330 340
pF1KB9 VARQMFHDALREPGKALASS-GFKYLEYE---RRHGSGE--WRQLGELLTDGVRSFREPA
.: : : :. .:... : : : . .:::: : . . . : . .... .
NP_892 KEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHG
260 270 280 290 300 310
350 360 370 380 390
pF1KB9 PAEALPQQYP-EPAPAA--LCGPPPRAP--SRNLAPTPRRRKASPEPEGEAAG-KMTTEE
. . ... ::: .: : : . :. .: : :.:: :::::::.. :.. :
NP_892 HSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEA
320 330 340 350 360 370
400 410 420 430
pF1KB9 QQQ---------------RHWVAP----GGPYSAET--PGVP----SPIAALKNVAEALG
: .:.: ..:.: .: : . ::.::: ::. :
NP_892 QPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAG
380 390 400 410 420 430
440 450 460 470 480 490
pF1KB9 --HSPKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARN-GEAEVSPTAGAEAVSGGG-
:. :: . . .: .. :: . :. . :.:: :. : .. :.: : : ..
NP_892 GSHASKDANQVHSTTRRNSNSPPSPSSMN---QRRLGPREVGGQGAGNTGGLEPVHPASL
440 450 460 470 480 490
500 510 520 530 540 550
pF1KB9 SGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGPAGEVYCPSGD
.. . .::::::::.:::::::::::::::.:::::::::. :: :: .::::::::.
NP_892 PDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGE
500 510 520 530 540 550
560 570 580
pF1KB9 KCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP
:::::::.:::::::::::::::::.:::::::
NP_892 KCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS
560 570 580
>>NP_001070865 (OMIM: 615332) interferon regulatory fact (571 aa)
initn: 1066 init1: 566 opt: 648 Z-score: 403.3 bits: 84.6 E(85289): 1e-15
Smith-Waterman score: 1009; 37.8% identity (55.7% similar) in 625 aa overlap (1-583:5-570)
10 20 30 40 50
pF1KB9 MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLK
.: . ::::: :::::::.:::::.:::.: :::::::.:::::.:..:..:::::
NP_001 MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 RSH-VLPEGRSPGPPALKHPATKDLAAAAAQGPQLPPPQA--QPQPSGTGGGVSGQDRYD
:.: .:::::: : : :.:::. : : . : : . :: . :
NP_001 RAHGCFPEGRSP-PGAA--------ASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAP
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 RATSSGRLPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGLMPPGLLAAAVSG
.: : :: . : . ::.. .: . .: :.. : .:: . . : .
NP_001 QALE--RYPLAAAAER---PPRLGSDFGSSRPAAS------LAQPPTPQPPPVNGILVPN
120 130 140 150 160
180 190 200 210 220 230
pF1KB9 LGSRGLTLAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEEWHGRPKAVREQL
: : : :. : . .:. : : : : : :.
NP_001 -GFSKLEEPPELNRQSP---------NPRRGHAVPPTLVPLMNGSATPL---PTALG---
170 180 190 200
240 250 260 270 280 290
pF1KB9 LALSACAPFNVRFKKDHGLVGRVFAFD--ATARPPGYEFELKLFTEYPCGSGNVYAGVLA
:. : : . . . .: . : : :: . . : .. :
NP_001 LGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAA--------A
210 220 230 240 250
300 310 320 330 340
pF1KB9 VARQMFHDALREPGKALASS-GFKYLEYE---RRHGSGE--WRQLGELLTDGVRSFREPA
.: : : :. .:... : : : . .:::: : . . . : . .... .
NP_001 KEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHG
260 270 280 290 300 310
350 360 370 380 390 400
pF1KB9 PAEALPQQYP-EPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAG-KMTTEEQQQ-
. . ... ::: .:. : : :.:: :::::::.. :.. : :
NP_001 HSGPFESKFKKEPALTAV------------ARTARKRKPSPEPEGEVGPPKINGEAQPWL
320 330 340 350 360
410 420 430
pF1KB9 --------------RHWVAP----GGPYSAET--PGVP----SPIAALKNVAEALG--HS
.:.: ..:.: .: : . ::.::: ::. : :.
NP_001 STSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHA
370 380 390 400 410 420
440 450 460 470 480 490
pF1KB9 PKDPGGGGGPVRAGGASPAASSTAQPPTQHRLVARN-GEAEVSPTAGAEAVSGGG-SGTG
:: . . .: .. :: . :. . :.:: :. : .. :.: : : .. ..
NP_001 SKDANQVHSTTRRNSNSPPSPSSMN---QRRLGPREVGGQGAGNTGGLEPVHPASLPDSS
430 440 450 460 470 480
500 510 520 530 540 550
pF1KB9 ATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGPAGEVYCPSGDKCPL
. .::::::::.:::::::::::::::.:::::::::. :: :: .::::::::.::::
NP_001 LATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPL
490 500 510 520 530 540
560 570 580
pF1KB9 VGSSVPWAFMQGEIATILAGDIKVKKERDP
:::.:::::::::::::::::.:::::::
NP_001 VGSNVPWAFMQGEIATILAGDVKVKKERDS
550 560 570
>>NP_078772 (OMIM: 611720) interferon regulatory factor (796 aa)
initn: 1584 init1: 577 opt: 616 Z-score: 382.3 bits: 81.1 E(85289): 1.5e-14
Smith-Waterman score: 1462; 45.9% identity (66.2% similar) in 604 aa overlap (68-584:207-796)
40 50 60 70 80 90
pF1KB9 NFEGADRIELLIDAARQLKRSHVLPEGRSPGPPAL--KHPATKDLAAAAA--QGPQLPPP
::: : . : ... ::..: .: .
NP_078 PVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLV
180 190 200 210 220 230
100 110 120 130 140
pF1KB9 QAQPQPSGTGG-------GVSGQDRYDRATSSGRLPLPSPALEYTLGSRLANGLGREEAV
. :.:.: :: .. : . .:.. :: : : ..:::: : .
NP_078 TGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPP---HALGSR-----GPPTPA
240 250 260 270 280
150 160 170 180 190 200
pF1KB9 AEGARR--ALLGSMPGLMPPGLLAAAVSGLGSRGLTLAPGLSPARP--LFGSDFEKE--K
:: : ::. ::. . ..: :. .: .. : . :: . ..: :.: .
NP_078 PPGAPGGPACLGGTPGVSATS--SSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKE
290 300 310 320 330 340
210 220 230 240 250 260
pF1KB9 QQRNADCLAELNEAMRGRAEEWHGRPKAVREQLLALSACAPFNVRFKKDHGLVGRVFAFD
.::::. ::::.:..:.::::: ..:: ::. ::.:..:.:..:::::::.:.:::::::
NP_078 KQRNAEALAELSESLRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFD
350 360 370 380 390 400
270 280 290 300 310 320
pF1KB9 ATARPPGYEFELKLFTEYPCGSGNVYAGVLAVARQMFHDALREPGKALASSGFKYLEYER
:...: :...::::: ::: ::::::... .::.::..: ... :..: ::::::::::.
NP_078 AVSKP-GMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGL-SSGFKYLEYEK
410 420 430 440 450 460
330 340 350 360
pF1KB9 RHGSGEWRQLGELLTDGVRSFREPAP-AEALPQQYPE---P-----------APAALCGP
.::::.:: ::.:: ..:: :.: .: :. ::: : . : ::.: :
NP_078 KHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGT
470 480 490 500 510 520
370 380 390 400
pF1KB9 ---PPRAPS-RNLAPTPRRRKASPEPEGEAAGKMTT-EEQQQRHWVA-------------
:: ::: :. : . :.::::::: : : . ::::...:.:
NP_078 GALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAG
530 540 550 560 570 580
410 420 430 440
pF1KB9 ----PG-------------GPYSAET-P------GVPSPIAALKNVAEALG--HSPKDPG
:: ::.: .: : . :::.::: .::..:: ::::: .
NP_078 GFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGS
590 600 610 620 630 640
450 460 470 480 490
pF1KB9 G---GGGPVRAGGASPAASSTAQPPTQHRLVARNGE-----AEVSPTA--GAEAVSGGG-
. . .: ...::. : :. : :.::..:::. : :.: : . : .
NP_078 SVHSTTASARRNSSSPV--SPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNI
650 660 670 680 690 700
500 510 520 530 540 550
pF1KB9 SGTGATPGAPLCCTLCRERLEDTHFVQCPSVPGHKFCFPCSREFIKAQGPAGEVYCPSGD
. . ..:::::.:.:::::::::::::::.:::::::::: ::::: .::::::::.
NP_078 PDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGE
710 720 730 740 750 760
560 570 580
pF1KB9 KCPLVGSSVPWAFMQGEIATILAGDIKVKKERDP
:::::::.:::::::::::::::::.::::::::
NP_078 KCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP
770 780 790
>--
initn: 452 init1: 340 opt: 411 Z-score: 260.3 bits: 58.6 E(85289): 9.2e-08
Smith-Waterman score: 424; 44.9% identity (62.3% similar) in 167 aa overlap (2-151:4-170)
10 20 30 40 50
pF1KB9 MASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRS
:.:..:::: :::::::.:::::.::::: :::::::.:::::::..:..::::::.
NP_078 MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRA
10 20 30 40 50 60
60 70 80 90 100
pF1KB9 H-VLPEGRSPGPP--------------ALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTG
: . .::::::: : :. :::::: : : : : .
NP_078 HGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 GGVSGQ--DRYDRATSSGRLPLPSPALEYTLGSRLANGLGREEAVAEGARRALLGSMPGL
. : .. : ... . : :: .: :.. : . . :: . .:
NP_078 QQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB9 MPPGLLAAAVSGLGSRGLTLAPGLSPARPLFGSDFEKEKQQRNADCLAELNEAMRGRAEE
NP_078 GSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLP
190 200 210 220 230 240
584 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:15:07 2016 done: Fri Nov 4 20:15:08 2016
Total Scan time: 10.120 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]