Result of FASTA (omim) for pF1KB9885
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9885, 653 aa
  1>>>pF1KB9885 653 - 653 aa - 653 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5820+/-0.000451; mu= 15.2856+/- 0.028
 mean_var=164.3745+/-34.027, 0's: 0 Z-trim(115.8): 213  B-trim: 1436 in 1/53
 Lambda= 0.100036
 statistics sampled from 26259 (26493) to 26259 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.311), width:  16
 Scan time: 11.660

The best scores are:                                      opt bits E(85289)
NP_036342 (OMIM: 254110,602290,615988) E3 ubiquiti ( 653) 4380 645.0 2.5e-184
XP_005251870 (OMIM: 254110,602290,615988) PREDICTE ( 653) 4380 645.0 2.5e-184
NP_001093149 (OMIM: 254110,602290,615988) E3 ubiqu ( 653) 4380 645.0 2.5e-184
XP_011516700 (OMIM: 254110,602290,615988) PREDICTE ( 653) 4380 645.0 2.5e-184
XP_016869975 (OMIM: 254110,602290,615988) PREDICTE ( 653) 4380 645.0 2.5e-184
NP_940988 (OMIM: 254780,608072) E3 ubiquitin-prote ( 395)  257 49.7 2.4e-05
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485)  258 49.9 2.5e-05
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475)  256 49.6   3e-05
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516)  256 49.7 3.2e-05
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488)  255 49.5 3.4e-05
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488)  237 46.9  0.0002
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518)  237 46.9 0.00021
XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261)  232 45.9 0.00022
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513)  235 46.7 0.00026
NP_569074 (OMIM: 605684) tripartite motif-containi ( 270)  230 45.6 0.00028
XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 421)  232 46.1 0.00031
XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 424)  232 46.1 0.00031
NP_008959 (OMIM: 609316) E3 ubiquitin-protein liga ( 425)  232 46.1 0.00031
NP_439893 (OMIM: 605701) tripartite motif-containi ( 395)  230 45.8 0.00036
NP_006769 (OMIM: 605701) tripartite motif-containi ( 481)  230 45.9 0.00041
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488)  230 45.9 0.00041
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488)  230 45.9 0.00041
NP_741983 (OMIM: 617007) tripartite motif-containi ( 493)  219 44.3  0.0012
XP_005273509 (OMIM: 617007) PREDICTED: tripartite  ( 298)  215 43.5  0.0013
XP_005266707 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203)  207 42.2  0.0023
XP_016881102 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203)  207 42.2  0.0023
NP_775828 (OMIM: 616512) E3 ubiquitin-protein liga ( 203)  207 42.2  0.0023
XP_005266709 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203)  207 42.2  0.0023
XP_011524181 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203)  207 42.2  0.0023
XP_011524180 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203)  207 42.2  0.0023
XP_016881101 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203)  207 42.2  0.0023
XP_005253240 (OMIM: 608487) PREDICTED: tripartite  ( 493)  212 43.3  0.0025
NP_149023 (OMIM: 608487) tripartite motif-containi ( 493)  212 43.3  0.0025
XP_006718421 (OMIM: 608487) PREDICTED: tripartite  ( 265)  207 42.3  0.0027
XP_016873952 (OMIM: 608487) PREDICTED: tripartite  ( 265)  207 42.3  0.0027
XP_011518729 (OMIM: 608487) PREDICTED: tripartite  ( 271)  207 42.3  0.0028
XP_016873951 (OMIM: 608487) PREDICTED: tripartite  ( 300)  207 42.3   0.003
XP_016873950 (OMIM: 608487) PREDICTED: tripartite  ( 310)  207 42.4   0.003
XP_011518728 (OMIM: 608487) PREDICTED: tripartite  ( 310)  207 42.4   0.003
XP_016873949 (OMIM: 608487) PREDICTED: tripartite  ( 314)  207 42.4  0.0031
NP_001307918 (OMIM: 253250,605073) E3 ubiquitin-pr ( 925)  214 43.9  0.0031
NP_001307917 (OMIM: 253250,605073) E3 ubiquitin-pr ( 925)  214 43.9  0.0031
NP_149084 (OMIM: 608487) tripartite motif-containi ( 326)  207 42.4  0.0031
XP_005253241 (OMIM: 608487) PREDICTED: tripartite  ( 326)  207 42.4  0.0031
XP_016880155 (OMIM: 253250,605073) PREDICTED: E3 u ( 947)  214 43.9  0.0032
XP_016880156 (OMIM: 253250,605073) PREDICTED: E3 u ( 947)  214 43.9  0.0032
XP_011523138 (OMIM: 253250,605073) PREDICTED: E3 u ( 950)  214 43.9  0.0032
XP_016880153 (OMIM: 253250,605073) PREDICTED: E3 u ( 956)  214 43.9  0.0032
NP_056109 (OMIM: 253250,605073) E3 ubiquitin-prote ( 964)  214 43.9  0.0032
NP_001005207 (OMIM: 253250,605073) E3 ubiquitin-pr ( 964)  214 43.9  0.0032


>>NP_036342 (OMIM: 254110,602290,615988) E3 ubiquitin-pr  (653 aa)
 initn: 4380 init1: 4380 opt: 4380  Z-score: 3430.2  bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
              550       560       570       580       590       600

              610       620       630       640       650   
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
              610       620       630       640       650   

>>XP_005251870 (OMIM: 254110,602290,615988) PREDICTED: E  (653 aa)
 initn: 4380 init1: 4380 opt: 4380  Z-score: 3430.2  bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
              550       560       570       580       590       600

              610       620       630       640       650   
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
              610       620       630       640       650   

>>NP_001093149 (OMIM: 254110,602290,615988) E3 ubiquitin  (653 aa)
 initn: 4380 init1: 4380 opt: 4380  Z-score: 3430.2  bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
              550       560       570       580       590       600

              610       620       630       640       650   
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
              610       620       630       640       650   

>>XP_011516700 (OMIM: 254110,602290,615988) PREDICTED: E  (653 aa)
 initn: 4380 init1: 4380 opt: 4380  Z-score: 3430.2  bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
              550       560       570       580       590       600

              610       620       630       640       650   
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
              610       620       630       640       650   

>>XP_016869975 (OMIM: 254110,602290,615988) PREDICTED: E  (653 aa)
 initn: 4380 init1: 4380 opt: 4380  Z-score: 3430.2  bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
              550       560       570       580       590       600

              610       620       630       640       650   
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
              610       620       630       640       650   

>>NP_940988 (OMIM: 254780,608072) E3 ubiquitin-protein l  (395 aa)
 initn: 369 init1: 151 opt: 257  Z-score: 217.0  bits: 49.7 E(85289): 2.4e-05
Smith-Waterman score: 321; 27.2% identity (55.1% similar) in 412 aa overlap (246-643:16-390)

         220       230       240       250        260       270    
pF1KB9 SNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLE-ETADEEEPELTASLPRELT
                                     ...:...::: ..  :.  .     ::.:.
NP_940                MAAEASESGPALHELMREAEISLLECKVCFEKFGHRQQRRPRNLS
                              10        20        30        40     

          280       290       300       310       320       330    
pF1KB9 LQDVELLKVGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVA
                :::  :    :. .:::. .:  .  .:   . .::  .  . .   :...
NP_940 --------CGHVVCLACVAALAHPRTLALECPFCRRAC-RGCDTSDCLPVLHLI--ELLG
                  50        60        70         80        90      

           340       350       360       370       380        390  
pF1KB9 SP-RASPAKQRGPEAASNIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQ-GEVLVADRGN
       :  : ::: .:.  .: .   :   . .:. :.   . : :..: .  . :.:.:.  : 
NP_940 SALRQSPAAHRAAPSAPGALTCH--HTFGGWGT---LVN-PTGLALCPKTGRVVVVHDGR
          100       110         120           130       140        

            400       410       420       430       440       450  
pF1KB9 YRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSL
        :...:   :   . . . .: :.      . :.   . .... .:.  . :::. : :.
NP_940 RRVKIFDSGGGCAH-QFGEKG-DA------AQDIRYPVDVTITNDCH--VVVTDAGDRSI
      150       160         170             180         190        

            460       470       480       490       500       510  
pF1KB9 KVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCS
       ::. . :.      .:.: :::. . :.. .::::.:.:.:  . :: . ::.. .    
NP_940 KVFDFFGQIKLVIGGQFSLPWGVETTPQNGIVVTDAEAGSLHLLDVDFAEGVLRRTE---
      200       210       220       230       240       250        

            520        530       540       550            560      
pF1KB9 AVRPKFVTCDAEGT-VYFTQGLGLNLENRQNEHHLEGGFSIGSV-----GPDGQLGRQIS
         : .   :. .:. : .  :    ::     : :  : .. :.     . . ::  :..
NP_940 --RLQAHLCNPRGVAVSWLTGAIAVLE-----HPLALGTGVCSTRVKVFSSSMQLVGQVD
           260       270       280            290       300        

         570       580        590       600       610          620 
pF1KB9 HF-FSENEDFRCIAG-MCVDARGDLIVADSSRKEILHFPKGGGYSV---LIREGLTCPVG
        : .:     .  :. .  : .:..::::.:   :: . :   . :   .. .::. ::.
NP_940 TFGLSLYFPSKITASAVTFDHQGNVIVADTSGPAILCLGKPEEFPVPKPMVTHGLSHPVA
      310       320       330       340       350       360        

             630       640       650   
pF1KB9 IALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
       ...: ...:::::  .: ::.:          
NP_940 LTFTKENSLLVLDTASHSIKVYKVDWG     
      370       380       390          

>>NP_060543 (OMIM: 613184) E3 ubiquitin-protein ligase T  (485 aa)
 initn: 117 init1:  71 opt: 258  Z-score: 216.7  bits: 49.9 E(85289): 2.5e-05
Smith-Waterman score: 258; 23.9% identity (59.6% similar) in 255 aa overlap (11-248:7-250)

               10        20        30        40        50          
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL---ASSIN
                 ..:. : . ::::: .: .:   :  . :::..:..::  :    . : :
NP_060     MDPTALVEAIVEEVACPICM-TFLRE---PMSIDCGHSFCHSCLSGLWEIPGESQN
                   10        20            30        40        50  

         60        70        80        90         100       110    
pF1KB9 -GVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLL--MCRSCGRRLPRQFCRS
        :  ::.:   ..  .:    .  .:.. .    :  ..::   .:.  :..: ..::. 
NP_060 WGYTCPLCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKL-KMFCKE
             60        70        80        90       100        110 

          120        130       140       150       160             
pF1KB9 CGLVLCEPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGEL------QRRK
         :..:: : .. .:.  .: ..:....: : . .. : : .:.. . :       .:..
NP_060 DVLIMCEACSQSPEHE--AHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKR
             120         130       140       150       160         

       170       180       190       200          210       220    
pF1KB9 AALEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKF---FTGSLAEVEKSNSQVVEEQ
       .:   ..  ...: .... :. . .: .. .    :..    ...:: ...  ....  :
NP_060 TATWKIQ--VETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETM--Q
     170         180       190       200       210       220       

          230       240        250       260       270       280   
pF1KB9 SYLLNIAEVQAVSRCDY-FLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKV
       .  :: .:.   :.  . ..:..:.                                   
NP_060 KLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLEL
         230       240       250       260       270       280     

>>NP_003132 (OMIM: 109092) E3 ubiquitin-protein ligase T  (475 aa)
 initn: 178 init1:  70 opt: 256  Z-score: 215.2  bits: 49.6 E(85289): 3e-05
Smith-Waterman score: 270; 25.8% identity (55.2% similar) in 299 aa overlap (6-290:2-279)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
            ::   :  . : . ::::.. :.:    :  ..:::..:..:. ..  .. .:  
NP_003     MASAARLTMMWEEVTCPICLDPFVE----PVSIECGHSFCQECISQV--GKGGGSV
                   10        20            30        40          50

               70           80        90       100       110       
pF1KB9 CPFCSKITRITSLT---QLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGL
       :: : .   . .:    ::.. .. :: :.  .  :..    :   :.:: . ::.. : 
NP_003 CPVCRQRFLLKNLRPNRQLANMVNNLKEISQEA-REGTQGERCAVHGERL-HLFCEKDGK
               60        70        80         90        100        

       120       130       140       150       160       170       
pF1KB9 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL
       .::  : .. ..   :  .:..:::.:    . :::   .  .:::.:..   : .  ..
NP_003 ALCWVCAQS-RKHRDHAMVPLEEAAQE----YQEKL---QVALGELRRKQELAEKLEVEI
      110        120       130              140       150       160

       180       190       200       210       220           230   
pF1KB9 QARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVE----EQSYLLNIAEV
         .     .    .. :.. :......:    :.: :. . : .:    ::  .:.  :.
NP_003 AIKRADWKKTVETQKSRIHAEFVQQKNF----LVEEEQRQLQELEKDEREQLRILGEKEA
              170       180           190       200       210      

           240       250              260       270       280      
pF1KB9 QAVSRCDYFLAKIKQAD-------VALLEETADEEEPELTASLPRELTLQDVELLKVGHV
       . ... . .   :.. :       . ::.:.    :   . .: ..: . . :: .: ::
NP_003 KLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNL-KDLDITSPELRSVCHV
        220       230       240       250        260       270     

        290       300       310       320       330       340      
pF1KB9 GPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGP
         :.                                                        
NP_003 PGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQ
         280       290       300       310       320       330     

>>NP_001003818 (OMIM: 607564) tripartite motif-containin  (516 aa)
 initn: 139 init1:  88 opt: 256  Z-score: 214.8  bits: 49.7 E(85289): 3.2e-05
Smith-Waterman score: 256; 24.9% identity (56.9% similar) in 269 aa overlap (3-262:27-285)

                                       10        20        30      
pF1KB9                         MAAAAASHLNLDALREVLECPICMESFTEEQLRPKL
                                 :. .: . .: .:: . ::::.: .::    :  
NP_001 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVD-IREEVTCPICLELLTE----PLS
               10        20        30         40        50         

         40        50        60            70           80         
pF1KB9 LHCGHTICRQCLEKLLASSINGVR----CPFCSKITRITSLT---QLTDNLTVLKIIDTA
       . :::..:. :.      :. : .    :: :.   .  .:    .:.. .  :. . . 
NP_001 IDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREV-VL
          60        70        80        90       100       110     

      90       100       110       120        130       140        
pF1KB9 GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPC-READHQPPGHCTLPVKEAAEERRRD
       : .. .  ..: . :..: . ::.  : :.:  : :  .:.  :: :. :.:.:.: .. 
NP_001 GPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLCERSQEHR--GHHTFLVEEVAQEYQEK
          120       130        140       150         160       170 

      150       160       170       180       190       200        
pF1KB9 FGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTG
       : :.: .:..   : ..  : ..  . . . ...    .   :  .... : : ..    
NP_001 FQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELK
             180       190       200       210       220       230 

      210       220       230       240       250        260       
pF1KB9 SLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQAD-VALLEETADEEEPELTA
       .: . ::.. ...::    : . ..:.. .    : .  :.. . ::....:  :     
NP_001 KLEQEEKKGLRIIEEAENDL-VHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFW
             240       250        260       270       280       290

       270       280       290       300       310       320       
pF1KB9 SLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDM
                                                                   
NP_001 TLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQ
              300       310       320       330       340       350

>>NP_477514 (OMIM: 607564) tripartite motif-containing p  (488 aa)
 initn: 139 init1:  88 opt: 255  Z-score: 214.3  bits: 49.5 E(85289): 3.4e-05
Smith-Waterman score: 255; 24.8% identity (56.6% similar) in 258 aa overlap (14-262:9-257)

               10        20        30        40        50        60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
                    .:: . ::::.: .::    :  . :::..:. :.      :. : .
NP_477      MTSPVLVDIREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQE
                    10        20            30        40        50 

                   70           80        90       100       110   
pF1KB9 ----CPFCSKITRITSLT---QLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCR
           :: :.   .  .:    .:.. .  :. . . : .. .  ..: . :..: . ::.
NP_477 GERSCPVCQTSYQPGNLRPNRHLANIVRRLREV-VLGPGKQLKAVLCADHGEKL-QLFCQ
              60        70        80         90       100          

           120        130       140       150       160       170  
pF1KB9 SCGLVLCEPC-READHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEG
         : :.:  : :  .:.  :: :. :.:.:.: .. : :.: .:..   : ..  : .. 
NP_477 EDGKVICWLCERSQEHR--GHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIRE
     110       120         130       140       150       160       

            180       190       200       210       220       230  
pF1KB9 VSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAE
        . . . ...    .   :  .... : : ..    .: . ::.. ...::    : . .
NP_477 KKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDL-VHQ
       170       180       190       200       210       220       

            240       250        260       270       280       290 
pF1KB9 VQAVSRCDYFLAKIKQAD-VALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQI
       .:.. .    : .  :.. . ::....:  :                             
NP_477 TQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRM
        230       240       250       260       270       280      

             300       310       320       330       340       350 
pF1KB9 GQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASN
                                                                   
NP_477 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLG
        290       300       310       320       330       340      




653 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:00:22 2016 done: Fri Nov  4 20:00:24 2016
 Total Scan time: 11.660 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com