FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9885, 653 aa
1>>>pF1KB9885 653 - 653 aa - 653 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5820+/-0.000451; mu= 15.2856+/- 0.028
mean_var=164.3745+/-34.027, 0's: 0 Z-trim(115.8): 213 B-trim: 1436 in 1/53
Lambda= 0.100036
statistics sampled from 26259 (26493) to 26259 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.311), width: 16
Scan time: 11.660
The best scores are: opt bits E(85289)
NP_036342 (OMIM: 254110,602290,615988) E3 ubiquiti ( 653) 4380 645.0 2.5e-184
XP_005251870 (OMIM: 254110,602290,615988) PREDICTE ( 653) 4380 645.0 2.5e-184
NP_001093149 (OMIM: 254110,602290,615988) E3 ubiqu ( 653) 4380 645.0 2.5e-184
XP_011516700 (OMIM: 254110,602290,615988) PREDICTE ( 653) 4380 645.0 2.5e-184
XP_016869975 (OMIM: 254110,602290,615988) PREDICTE ( 653) 4380 645.0 2.5e-184
NP_940988 (OMIM: 254780,608072) E3 ubiquitin-prote ( 395) 257 49.7 2.4e-05
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485) 258 49.9 2.5e-05
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 256 49.6 3e-05
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 256 49.7 3.2e-05
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 255 49.5 3.4e-05
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 237 46.9 0.0002
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 237 46.9 0.00021
XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261) 232 45.9 0.00022
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 235 46.7 0.00026
NP_569074 (OMIM: 605684) tripartite motif-containi ( 270) 230 45.6 0.00028
XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 421) 232 46.1 0.00031
XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 424) 232 46.1 0.00031
NP_008959 (OMIM: 609316) E3 ubiquitin-protein liga ( 425) 232 46.1 0.00031
NP_439893 (OMIM: 605701) tripartite motif-containi ( 395) 230 45.8 0.00036
NP_006769 (OMIM: 605701) tripartite motif-containi ( 481) 230 45.9 0.00041
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 230 45.9 0.00041
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 230 45.9 0.00041
NP_741983 (OMIM: 617007) tripartite motif-containi ( 493) 219 44.3 0.0012
XP_005273509 (OMIM: 617007) PREDICTED: tripartite ( 298) 215 43.5 0.0013
XP_005266707 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 207 42.2 0.0023
XP_016881102 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 207 42.2 0.0023
NP_775828 (OMIM: 616512) E3 ubiquitin-protein liga ( 203) 207 42.2 0.0023
XP_005266709 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 207 42.2 0.0023
XP_011524181 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 207 42.2 0.0023
XP_011524180 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 207 42.2 0.0023
XP_016881101 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 207 42.2 0.0023
XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 212 43.3 0.0025
NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 212 43.3 0.0025
XP_006718421 (OMIM: 608487) PREDICTED: tripartite ( 265) 207 42.3 0.0027
XP_016873952 (OMIM: 608487) PREDICTED: tripartite ( 265) 207 42.3 0.0027
XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 207 42.3 0.0028
XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 207 42.3 0.003
XP_016873950 (OMIM: 608487) PREDICTED: tripartite ( 310) 207 42.4 0.003
XP_011518728 (OMIM: 608487) PREDICTED: tripartite ( 310) 207 42.4 0.003
XP_016873949 (OMIM: 608487) PREDICTED: tripartite ( 314) 207 42.4 0.0031
NP_001307918 (OMIM: 253250,605073) E3 ubiquitin-pr ( 925) 214 43.9 0.0031
NP_001307917 (OMIM: 253250,605073) E3 ubiquitin-pr ( 925) 214 43.9 0.0031
NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 207 42.4 0.0031
XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 207 42.4 0.0031
XP_016880155 (OMIM: 253250,605073) PREDICTED: E3 u ( 947) 214 43.9 0.0032
XP_016880156 (OMIM: 253250,605073) PREDICTED: E3 u ( 947) 214 43.9 0.0032
XP_011523138 (OMIM: 253250,605073) PREDICTED: E3 u ( 950) 214 43.9 0.0032
XP_016880153 (OMIM: 253250,605073) PREDICTED: E3 u ( 956) 214 43.9 0.0032
NP_056109 (OMIM: 253250,605073) E3 ubiquitin-prote ( 964) 214 43.9 0.0032
NP_001005207 (OMIM: 253250,605073) E3 ubiquitin-pr ( 964) 214 43.9 0.0032
>>NP_036342 (OMIM: 254110,602290,615988) E3 ubiquitin-pr (653 aa)
initn: 4380 init1: 4380 opt: 4380 Z-score: 3430.2 bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
550 560 570 580 590 600
610 620 630 640 650
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
610 620 630 640 650
>>XP_005251870 (OMIM: 254110,602290,615988) PREDICTED: E (653 aa)
initn: 4380 init1: 4380 opt: 4380 Z-score: 3430.2 bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
550 560 570 580 590 600
610 620 630 640 650
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
610 620 630 640 650
>>NP_001093149 (OMIM: 254110,602290,615988) E3 ubiquitin (653 aa)
initn: 4380 init1: 4380 opt: 4380 Z-score: 3430.2 bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
550 560 570 580 590 600
610 620 630 640 650
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
610 620 630 640 650
>>XP_011516700 (OMIM: 254110,602290,615988) PREDICTED: E (653 aa)
initn: 4380 init1: 4380 opt: 4380 Z-score: 3430.2 bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
550 560 570 580 590 600
610 620 630 640 650
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
610 620 630 640 650
>>XP_016869975 (OMIM: 254110,602290,615988) PREDICTED: E (653 aa)
initn: 4380 init1: 4380 opt: 4380 Z-score: 3430.2 bits: 645.0 E(85289): 2.5e-184
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
550 560 570 580 590 600
610 620 630 640 650
pF1KB9 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
610 620 630 640 650
>>NP_940988 (OMIM: 254780,608072) E3 ubiquitin-protein l (395 aa)
initn: 369 init1: 151 opt: 257 Z-score: 217.0 bits: 49.7 E(85289): 2.4e-05
Smith-Waterman score: 321; 27.2% identity (55.1% similar) in 412 aa overlap (246-643:16-390)
220 230 240 250 260 270
pF1KB9 SNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLE-ETADEEEPELTASLPRELT
...:...::: .. :. . ::.:.
NP_940 MAAEASESGPALHELMREAEISLLECKVCFEKFGHRQQRRPRNLS
10 20 30 40
280 290 300 310 320 330
pF1KB9 LQDVELLKVGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVA
::: : :. .:::. .: . .: . .:: . . . :...
NP_940 --------CGHVVCLACVAALAHPRTLALECPFCRRAC-RGCDTSDCLPVLHLI--ELLG
50 60 70 80 90
340 350 360 370 380 390
pF1KB9 SP-RASPAKQRGPEAASNIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQ-GEVLVADRGN
: : ::: .:. .: . : . .:. :. . : :..: . . :.:.:. :
NP_940 SALRQSPAAHRAAPSAPGALTCH--HTFGGWGT---LVN-PTGLALCPKTGRVVVVHDGR
100 110 120 130 140
400 410 420 430 440 450
pF1KB9 YRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSL
:...: : . . . .: :. . :. . .... .:. . :::. : :.
NP_940 RRVKIFDSGGGCAH-QFGEKG-DA------AQDIRYPVDVTITNDCH--VVVTDAGDRSI
150 160 170 180 190
460 470 480 490 500 510
pF1KB9 KVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCS
::. . :. .:.: :::. . :.. .::::.:.:.: . :: . ::.. .
NP_940 KVFDFFGQIKLVIGGQFSLPWGVETTPQNGIVVTDAEAGSLHLLDVDFAEGVLRRTE---
200 210 220 230 240 250
520 530 540 550 560
pF1KB9 AVRPKFVTCDAEGT-VYFTQGLGLNLENRQNEHHLEGGFSIGSV-----GPDGQLGRQIS
: . :. .:. : . : :: : : : .. :. . . :: :..
NP_940 --RLQAHLCNPRGVAVSWLTGAIAVLE-----HPLALGTGVCSTRVKVFSSSMQLVGQVD
260 270 280 290 300
570 580 590 600 610 620
pF1KB9 HF-FSENEDFRCIAG-MCVDARGDLIVADSSRKEILHFPKGGGYSV---LIREGLTCPVG
: .: . :. . : .:..::::.: :: . : . : .. .::. ::.
NP_940 TFGLSLYFPSKITASAVTFDHQGNVIVADTSGPAILCLGKPEEFPVPKPMVTHGLSHPVA
310 320 330 340 350 360
630 640 650
pF1KB9 IALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
...: ...::::: .: ::.:
NP_940 LTFTKENSLLVLDTASHSIKVYKVDWG
370 380 390
>>NP_060543 (OMIM: 613184) E3 ubiquitin-protein ligase T (485 aa)
initn: 117 init1: 71 opt: 258 Z-score: 216.7 bits: 49.9 E(85289): 2.5e-05
Smith-Waterman score: 258; 23.9% identity (59.6% similar) in 255 aa overlap (11-248:7-250)
10 20 30 40 50
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL---ASSIN
..:. : . ::::: .: .: : . :::..:..:: : . : :
NP_060 MDPTALVEAIVEEVACPICM-TFLRE---PMSIDCGHSFCHSCLSGLWEIPGESQN
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 -GVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLL--MCRSCGRRLPRQFCRS
: ::.: .. .: . .:.. . : ..:: .:. :..: ..::.
NP_060 WGYTCPLCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKL-KMFCKE
60 70 80 90 100 110
120 130 140 150 160
pF1KB9 CGLVLCEPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGEL------QRRK
:..:: : .. .:. .: ..:....: : . .. : : .:.. . : .:..
NP_060 DVLIMCEACSQSPEHE--AHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKR
120 130 140 150 160
170 180 190 200 210 220
pF1KB9 AALEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKF---FTGSLAEVEKSNSQVVEEQ
.: .. ...: .... :. . .: .. . :.. ...:: ... .... :
NP_060 TATWKIQ--VETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETM--Q
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 SYLLNIAEVQAVSRCDY-FLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKV
. :: .:. :. . ..:..:.
NP_060 KLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLEL
230 240 250 260 270 280
>>NP_003132 (OMIM: 109092) E3 ubiquitin-protein ligase T (475 aa)
initn: 178 init1: 70 opt: 256 Z-score: 215.2 bits: 49.6 E(85289): 3e-05
Smith-Waterman score: 270; 25.8% identity (55.2% similar) in 299 aa overlap (6-290:2-279)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
:: : . : . ::::.. :.: : ..:::..:..:. .. .. .:
NP_003 MASAARLTMMWEEVTCPICLDPFVE----PVSIECGHSFCQECISQV--GKGGGSV
10 20 30 40 50
70 80 90 100 110
pF1KB9 CPFCSKITRITSLT---QLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGL
:: : . . .: ::.. .. :: :. . :.. : :.:: . ::.. :
NP_003 CPVCRQRFLLKNLRPNRQLANMVNNLKEISQEA-REGTQGERCAVHGERL-HLFCEKDGK
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL
.:: : .. .. : .:..:::.: . ::: . .:::.:.. : . ..
NP_003 ALCWVCAQS-RKHRDHAMVPLEEAAQE----YQEKL---QVALGELRRKQELAEKLEVEI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 QARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVE----EQSYLLNIAEV
. . .. :.. :......: :.: :. . : .: :: .:. :.
NP_003 AIKRADWKKTVETQKSRIHAEFVQQKNF----LVEEEQRQLQELEKDEREQLRILGEKEA
170 180 190 200 210
240 250 260 270 280
pF1KB9 QAVSRCDYFLAKIKQAD-------VALLEETADEEEPELTASLPRELTLQDVELLKVGHV
. ... . . :.. : . ::.:. : . .: ..: . . :: .: ::
NP_003 KLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNL-KDLDITSPELRSVCHV
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB9 GPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGP
:.
NP_003 PGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQ
280 290 300 310 320 330
>>NP_001003818 (OMIM: 607564) tripartite motif-containin (516 aa)
initn: 139 init1: 88 opt: 256 Z-score: 214.8 bits: 49.7 E(85289): 3.2e-05
Smith-Waterman score: 256; 24.9% identity (56.9% similar) in 269 aa overlap (3-262:27-285)
10 20 30
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKL
:. .: . .: .:: . ::::.: .:: :
NP_001 MCGSERILQAGNILEIRVGQAGARRVATMTSPVLVD-IREEVTCPICLELLTE----PLS
10 20 30 40 50
40 50 60 70 80
pF1KB9 LHCGHTICRQCLEKLLASSINGVR----CPFCSKITRITSLT---QLTDNLTVLKIIDTA
. :::..:. :. :. : . :: :. . .: .:.. . :. . .
NP_001 IDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRPNRHLANIVRRLREV-VL
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB9 GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPC-READHQPPGHCTLPVKEAAEERRRD
: .. . ..: . :..: . ::. : :.: : : .:. :: :. :.:.:.: ..
NP_001 GPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLCERSQEHR--GHHTFLVEEVAQEYQEK
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB9 FGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTG
: :.: .:.. : .. : .. . . . ... . : .... : : ..
NP_001 FQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELK
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB9 SLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQAD-VALLEETADEEEPELTA
.: . ::.. ...:: : . ..:.. . : . :.. . ::....: :
NP_001 KLEQEEKKGLRIIEEAENDL-VHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFW
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB9 SLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDM
NP_001 TLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQ
300 310 320 330 340 350
>>NP_477514 (OMIM: 607564) tripartite motif-containing p (488 aa)
initn: 139 init1: 88 opt: 255 Z-score: 214.3 bits: 49.5 E(85289): 3.4e-05
Smith-Waterman score: 255; 24.8% identity (56.6% similar) in 258 aa overlap (14-262:9-257)
10 20 30 40 50 60
pF1KB9 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
.:: . ::::.: .:: : . :::..:. :. :. : .
NP_477 MTSPVLVDIREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQE
10 20 30 40 50
70 80 90 100 110
pF1KB9 ----CPFCSKITRITSLT---QLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCR
:: :. . .: .:.. . :. . . : .. . ..: . :..: . ::.
NP_477 GERSCPVCQTSYQPGNLRPNRHLANIVRRLREV-VLGPGKQLKAVLCADHGEKL-QLFCQ
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 SCGLVLCEPC-READHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEG
: :.: : : .:. :: :. :.:.:.: .. : :.: .:.. : .. : ..
NP_477 EDGKVICWLCERSQEHR--GHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIRE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 VSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAE
. . . ... . : .... : : .. .: . ::.. ...:: : . .
NP_477 KKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDL-VHQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 VQAVSRCDYFLAKIKQAD-VALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQI
.:.. . : . :.. . ::....: :
NP_477 TQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRM
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 GQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASN
NP_477 LRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLG
290 300 310 320 330 340
653 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:00:22 2016 done: Fri Nov 4 20:00:24 2016
Total Scan time: 11.660 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]