FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9897, 510 aa 1>>>pF1KB9897 510 - 510 aa - 510 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3064+/-0.0014; mu= -1.5771+/- 0.080 mean_var=453.5750+/-102.858, 0's: 0 Z-trim(106.5): 466 B-trim: 0 in 0/53 Lambda= 0.060221 statistics sampled from 8471 (9024) to 8471 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.277), width: 16 Scan time: 3.460 The best scores are: opt bits E(32554) CCDS46259.1 EIF2AK2 gene_id:5610|Hs108|chr2 ( 510) 3303 302.7 6.2e-82 CCDS1786.1 EIF2AK2 gene_id:5610|Hs108|chr2 ( 551) 1664 160.4 4.8e-39 >>CCDS46259.1 EIF2AK2 gene_id:5610|Hs108|chr2 (510 aa) initn: 3303 init1: 3303 opt: 3303 Z-score: 1584.4 bits: 302.7 E(32554): 6.2e-82 Smith-Waterman score: 3303; 100.0% identity (100.0% similar) in 510 aa overlap (1-510:1-510) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RSLAPRFDLPDMKETKYTVDKRKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RSLAPRFDLPDMKETKYTVDKRKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 VDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSK 430 440 450 460 470 480 490 500 510 pF1KB9 KPEDRPNTSEILRTLTVWKKSPEKNERHTC :::::::::::::::::::::::::::::: CCDS46 KPEDRPNTSEILRTLTVWKKSPEKNERHTC 490 500 510 >>CCDS1786.1 EIF2AK2 gene_id:5610|Hs108|chr2 (551 aa) initn: 1703 init1: 1664 opt: 1664 Z-score: 814.5 bits: 160.4 E(32554): 4.8e-39 Smith-Waterman score: 3141; 92.4% identity (92.4% similar) in 542 aa overlap (1-501:1-542) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 pF1KB9 RSLAPRFDLPDMKETKYTVDKR-------------------------------------- :::::::::::::::::::::: CCDS17 RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY 250 260 270 280 290 300 270 280 290 300 310 pF1KB9 ---KAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB9 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI 370 380 390 400 410 420 380 390 400 410 420 430 pF1KB9 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE 430 440 450 460 470 480 440 450 460 470 480 490 pF1KB9 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK 490 500 510 520 530 540 500 510 pF1KB9 KSPEKNERHTC :: CCDS17 KSPEKNERHTC 550 510 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 18:32:24 2016 done: Sun Nov 6 18:32:25 2016 Total Scan time: 3.460 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]