FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9897, 510 aa 1>>>pF1KB9897 510 - 510 aa - 510 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.0088+/-0.000759; mu= -23.2357+/- 0.045 mean_var=1148.5217+/-261.513, 0's: 0 Z-trim(114.2): 194 B-trim: 0 in 0/55 Lambda= 0.037845 statistics sampled from 23785 (23913) to 23785 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.28), width: 16 Scan time: 10.580 The best scores are: opt bits E(85289) NP_001129124 (OMIM: 176871) interferon-induced, do ( 510) 3303 197.5 7.8e-50 XP_016859992 (OMIM: 176871) PREDICTED: interferon- ( 508) 2177 136.0 2.5e-31 NP_002750 (OMIM: 176871) interferon-induced, doubl ( 551) 1664 108.1 7.1e-23 XP_011531289 (OMIM: 176871) PREDICTED: interferon- ( 551) 1664 108.1 7.1e-23 NP_001129123 (OMIM: 176871) interferon-induced, do ( 551) 1664 108.1 7.1e-23 >>NP_001129124 (OMIM: 176871) interferon-induced, double (510 aa) initn: 3303 init1: 3303 opt: 3303 Z-score: 1015.6 bits: 197.5 E(85289): 7.8e-50 Smith-Waterman score: 3303; 100.0% identity (100.0% similar) in 510 aa overlap (1-510:1-510) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RSLAPRFDLPDMKETKYTVDKRKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSLAPRFDLPDMKETKYTVDKRKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 VDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSK 430 440 450 460 470 480 490 500 510 pF1KB9 KPEDRPNTSEILRTLTVWKKSPEKNERHTC :::::::::::::::::::::::::::::: NP_001 KPEDRPNTSEILRTLTVWKKSPEKNERHTC 490 500 510 >>XP_016859992 (OMIM: 176871) PREDICTED: interferon-indu (508 aa) initn: 2288 init1: 1664 opt: 2177 Z-score: 683.4 bits: 136.0 E(85289): 2.5e-31 Smith-Waterman score: 2838; 84.8% identity (84.8% similar) in 551 aa overlap (1-510:1-508) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 pF1KB9 RSLAPRFDLPDMKETKYTVDKR-------------------------------------- :::::::::::::::::::::: XP_016 RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY 250 260 270 280 290 300 270 280 290 300 310 pF1KB9 ---KAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB9 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLK---- 370 380 390 400 410 380 390 400 410 420 430 pF1KB9 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE ::::::::::::::::::::: XP_016 ---------------------------------------ISSQDYGKEVDLYALGLILAE 420 430 440 450 460 470 480 490 pF1KB9 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK 440 450 460 470 480 490 500 510 pF1KB9 KSPEKNERHTC ::::::::::: XP_016 KSPEKNERHTC 500 >>NP_002750 (OMIM: 176871) interferon-induced, double-st (551 aa) initn: 1703 init1: 1664 opt: 1664 Z-score: 531.7 bits: 108.1 E(85289): 7.1e-23 Smith-Waterman score: 3141; 92.4% identity (92.4% similar) in 542 aa overlap (1-501:1-542) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 pF1KB9 RSLAPRFDLPDMKETKYTVDKR-------------------------------------- :::::::::::::::::::::: NP_002 RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY 250 260 270 280 290 300 270 280 290 300 310 pF1KB9 ---KAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB9 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI 370 380 390 400 410 420 380 390 400 410 420 430 pF1KB9 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE 430 440 450 460 470 480 440 450 460 470 480 490 pF1KB9 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK 490 500 510 520 530 540 500 510 pF1KB9 KSPEKNERHTC :: NP_002 KSPEKNERHTC 550 >>XP_011531289 (OMIM: 176871) PREDICTED: interferon-indu (551 aa) initn: 1703 init1: 1664 opt: 1664 Z-score: 531.7 bits: 108.1 E(85289): 7.1e-23 Smith-Waterman score: 3141; 92.4% identity (92.4% similar) in 542 aa overlap (1-501:1-542) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 pF1KB9 RSLAPRFDLPDMKETKYTVDKR-------------------------------------- :::::::::::::::::::::: XP_011 RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY 250 260 270 280 290 300 270 280 290 300 310 pF1KB9 ---KAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB9 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI 370 380 390 400 410 420 380 390 400 410 420 430 pF1KB9 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE 430 440 450 460 470 480 440 450 460 470 480 490 pF1KB9 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK 490 500 510 520 530 540 500 510 pF1KB9 KSPEKNERHTC :: XP_011 KSPEKNERHTC 550 >>NP_001129123 (OMIM: 176871) interferon-induced, double (551 aa) initn: 1703 init1: 1664 opt: 1664 Z-score: 531.7 bits: 108.1 E(85289): 7.1e-23 Smith-Waterman score: 3141; 92.4% identity (92.4% similar) in 542 aa overlap (1-501:1-542) 10 20 30 40 50 60 pF1KB9 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK 190 200 210 220 230 240 250 260 pF1KB9 RSLAPRFDLPDMKETKYTVDKR-------------------------------------- :::::::::::::::::::::: NP_001 RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY 250 260 270 280 290 300 270 280 290 300 310 pF1KB9 ---KAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB9 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI 370 380 390 400 410 420 380 390 400 410 420 430 pF1KB9 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE 430 440 450 460 470 480 440 450 460 470 480 490 pF1KB9 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK 490 500 510 520 530 540 500 510 pF1KB9 KSPEKNERHTC :: NP_001 KSPEKNERHTC 550 510 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 18:32:25 2016 done: Sun Nov 6 18:32:27 2016 Total Scan time: 10.580 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]