FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9908, 589 aa 1>>>pF1KB9908 589 - 589 aa - 589 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4861+/-0.000452; mu= 4.6920+/- 0.027 mean_var=485.2688+/-111.857, 0's: 0 Z-trim(119.7): 1600 B-trim: 644 in 1/54 Lambda= 0.058221 statistics sampled from 31634 (33964) to 31634 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.398), width: 16 Scan time: 11.940 The best scores are: opt bits E(85289) NP_002073 (OMIM: 600869) G protein-coupled recepto ( 589) 4049 355.7 2.4e-97 NP_001004105 (OMIM: 600869) G protein-coupled rece ( 560) 3860 339.8 1.4e-92 NP_001004106 (OMIM: 600869) G protein-coupled rece ( 576) 3853 339.2 2.2e-92 XP_006714922 (OMIM: 600869) PREDICTED: G protein-c ( 557) 3840 338.1 4.6e-92 XP_006714921 (OMIM: 600869) PREDICTED: G protein-c ( 559) 3727 328.6 3.3e-89 XP_011532839 (OMIM: 600869) PREDICTED: G protein-c ( 550) 3453 305.6 2.8e-82 NP_005299 (OMIM: 600870) G protein-coupled recepto ( 590) 2836 253.8 1.1e-66 NP_892027 (OMIM: 137026) G protein-coupled recepto ( 578) 2632 236.7 1.6e-61 XP_005269765 (OMIM: 600870) PREDICTED: G protein-c ( 558) 2557 230.4 1.3e-59 NP_001004057 (OMIM: 137026) G protein-coupled rece ( 532) 2529 228.0 6.3e-59 NP_001004056 (OMIM: 137026) G protein-coupled rece ( 546) 2412 218.2 5.8e-56 NP_005298 (OMIM: 137026) G protein-coupled recepto ( 500) 2309 209.5 2.2e-53 XP_011532840 (OMIM: 600869) PREDICTED: G protein-c ( 324) 2252 204.3 5e-52 XP_016863543 (OMIM: 137026) PREDICTED: G protein-c ( 486) 2077 189.9 1.6e-47 XP_016863545 (OMIM: 137026) PREDICTED: G protein-c ( 440) 2070 189.3 2.3e-47 XP_016863544 (OMIM: 137026) PREDICTED: G protein-c ( 454) 1857 171.4 5.7e-42 XP_011511751 (OMIM: 137026) PREDICTED: G protein-c ( 585) 1854 171.3 7.7e-42 XP_016863549 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1815 167.8 6.1e-41 XP_016863548 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1815 167.8 6.1e-41 XP_016863546 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1815 167.8 6.1e-41 XP_016863547 (OMIM: 137026) PREDICTED: G protein-c ( 384) 1815 167.8 6.1e-41 XP_016863541 (OMIM: 137026) PREDICTED: G protein-c ( 591) 1811 167.7 9.5e-41 XP_011511750 (OMIM: 137026) PREDICTED: G protein-c ( 611) 1809 167.6 1.1e-40 XP_011511749 (OMIM: 137026) PREDICTED: G protein-c ( 617) 1806 167.4 1.3e-40 NP_002920 (OMIM: 180381,613411) rhodopsin kinase [ ( 563) 1759 163.3 1.9e-39 XP_016863550 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1727 160.3 1e-38 XP_005248019 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1727 160.3 1e-38 XP_006713943 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1727 160.3 1e-38 XP_016863551 (OMIM: 137026) PREDICTED: G protein-c ( 367) 1727 160.3 1e-38 XP_016863552 (OMIM: 137026) PREDICTED: G protein-c ( 338) 1712 159.0 2.3e-38 XP_011511752 (OMIM: 137026) PREDICTED: G protein-c ( 571) 1703 158.6 5e-38 NP_631948 (OMIM: 606987) rhodopsin kinase [Homo sa ( 553) 1652 154.3 9.6e-37 XP_016861206 (OMIM: 606987) PREDICTED: rhodopsin k ( 553) 1652 154.3 9.6e-37 XP_005269764 (OMIM: 600870) PREDICTED: G protein-c ( 560) 1642 153.5 1.7e-36 XP_011511755 (OMIM: 137026) PREDICTED: G protein-c ( 525) 1456 137.8 8.5e-32 XP_016863553 (OMIM: 137026) PREDICTED: G protein-c ( 338) 1262 121.2 5.5e-27 XP_016863555 (OMIM: 137026) PREDICTED: G protein-c ( 292) 1260 120.9 5.7e-27 XP_011511754 (OMIM: 137026) PREDICTED: G protein-c ( 565) 1253 120.8 1.2e-26 XP_011511753 (OMIM: 137026) PREDICTED: G protein-c ( 571) 1253 120.8 1.2e-26 XP_011511756 (OMIM: 137026) PREDICTED: G protein-c ( 525) 1251 120.6 1.3e-26 XP_011511757 (OMIM: 137026) PREDICTED: G protein-c ( 479) 1244 120.0 1.9e-26 XP_016876173 (OMIM: 180381,613411) PREDICTED: rhod ( 328) 1179 114.2 6.8e-25 NP_005151 (OMIM: 109636) beta-adrenergic receptor ( 688) 1128 110.5 1.9e-23 NP_001610 (OMIM: 109635) beta-adrenergic receptor ( 689) 1108 108.8 6.1e-23 XP_011543075 (OMIM: 109635) PREDICTED: beta-adrene ( 659) 1092 107.4 1.5e-22 XP_011528277 (OMIM: 109636) PREDICTED: beta-adrene ( 523) 1013 100.6 1.3e-20 XP_016863542 (OMIM: 137026) PREDICTED: G protein-c ( 587) 895 90.8 1.4e-17 XP_016863554 (OMIM: 137026) PREDICTED: G protein-c ( 290) 828 84.7 4.8e-16 XP_011511759 (OMIM: 137026) PREDICTED: G protein-c ( 306) 828 84.7 4.9e-16 XP_011511758 (OMIM: 137026) PREDICTED: G protein-c ( 370) 746 77.9 6.4e-14 >>NP_002073 (OMIM: 600869) G protein-coupled receptor ki (589 aa) initn: 4049 init1: 4049 opt: 4049 Z-score: 1868.5 bits: 355.7 E(85289): 2.4e-97 Smith-Waterman score: 4049; 100.0% identity (100.0% similar) in 589 aa overlap (1-589:1-589) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 490 500 510 520 530 540 550 560 570 580 pF1KB9 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR ::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 550 560 570 580 >>NP_001004105 (OMIM: 600869) G protein-coupled receptor (560 aa) initn: 3860 init1: 3860 opt: 3860 Z-score: 1782.9 bits: 339.8 E(85289): 1.4e-92 Smith-Waterman score: 3860; 100.0% identity (100.0% similar) in 560 aa overlap (1-560:1-560) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 490 500 510 520 530 540 550 560 570 580 pF1KB9 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR :::::::::::::::::::: NP_001 GQPPAPPKKGLLQRLFSRQR 550 560 >>NP_001004106 (OMIM: 600869) G protein-coupled receptor (576 aa) initn: 3853 init1: 3853 opt: 3853 Z-score: 1779.6 bits: 339.2 E(85289): 2.2e-92 Smith-Waterman score: 3853; 100.0% identity (100.0% similar) in 559 aa overlap (1-559:1-559) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 490 500 510 520 530 540 550 560 570 580 pF1KB9 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR ::::::::::::::::::: NP_001 GQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL 550 560 570 >>XP_006714922 (OMIM: 600869) PREDICTED: G protein-coupl (557 aa) initn: 3840 init1: 3840 opt: 3840 Z-score: 1773.9 bits: 338.1 E(85289): 4.6e-92 Smith-Waterman score: 3840; 100.0% identity (100.0% similar) in 557 aa overlap (33-589:1-557) 10 20 30 40 50 60 pF1KB9 LENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPI :::::::::::::::::::::::::::::: XP_006 MLQFPHISQCEELRLSLERDYHSLCERQPI 10 20 30 70 80 90 100 110 120 pF1KB9 GRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVP 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB9 RQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVT 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 KNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB9 SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDL 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 HRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERY 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 TFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQ 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 LLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQ 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB9 FSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQ 460 470 480 490 500 510 550 560 570 580 pF1KB9 PPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 520 530 540 550 >>XP_006714921 (OMIM: 600869) PREDICTED: G protein-coupl (559 aa) initn: 3727 init1: 3727 opt: 3727 Z-score: 1722.6 bits: 328.6 E(85289): 3.3e-89 Smith-Waterman score: 3727; 99.6% identity (99.6% similar) in 543 aa overlap (47-589:17-559) 20 30 40 50 60 70 pF1KB9 EGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPE : ::::::::::::::::::::::::::: XP_006 MPHPCALGLWTQQLPSLPTERDYHSLCERQPIGRLLFREFCATRPE 10 20 30 40 80 90 100 110 120 130 pF1KB9 LSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQG 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB9 PCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGG 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB9 FGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETK 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB9 DALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPEN 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB9 ILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLY 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB9 EMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRG 350 360 370 380 390 400 440 450 460 470 480 490 pF1KB9 GSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQ 410 420 430 440 450 460 500 510 520 530 540 550 pF1KB9 DFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLF 470 480 490 500 510 520 560 570 580 pF1KB9 SRQRIAVETAATARKSSPPASSPQPEAPTSSWR ::::::::::::::::::::::::::::::::: XP_006 SRQRIAVETAATARKSSPPASSPQPEAPTSSWR 530 540 550 >>XP_011532839 (OMIM: 600869) PREDICTED: G protein-coupl (550 aa) initn: 3453 init1: 3453 opt: 3453 Z-score: 1598.2 bits: 305.6 E(85289): 2.8e-82 Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 502 aa overlap (88-589:49-550) 60 70 80 90 100 110 pF1KB9 ERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDL :::::::::::::::::::::::::::::: XP_011 VEIAKAKARNGGRCSSSLTSASAKSCGSASAEYEVTPDDKRKACGRQLTQNFLSHTGPDL 20 30 40 50 60 70 120 130 140 150 160 170 pF1KB9 IPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLE 80 90 100 110 120 130 180 190 200 210 220 230 pF1KB9 RQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQI 140 150 160 170 180 190 240 250 260 270 280 290 pF1KB9 LEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICC 200 210 220 230 240 250 300 310 320 330 340 350 pF1KB9 GLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVV 260 270 280 290 300 310 360 370 380 390 400 410 pF1KB9 KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQAR 320 330 340 350 360 370 420 430 440 450 460 470 pF1KB9 SLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDV 380 390 400 410 420 430 480 490 500 510 520 530 pF1KB9 LDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDL 440 450 460 470 480 490 540 550 560 570 580 pF1KB9 DWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 500 510 520 530 540 550 >>NP_005299 (OMIM: 600870) G protein-coupled receptor ki (590 aa) initn: 2866 init1: 2729 opt: 2836 Z-score: 1317.9 bits: 253.8 E(85289): 1.1e-66 Smith-Waterman score: 2836; 70.9% identity (88.7% similar) in 573 aa overlap (1-573:1-572) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ :::::::::::::::::::::.::::::::...:.::::::::.:: ...::: :::..: NP_005 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE ::::::::.:: ::: : . :::.:::::::::.: :... ..:. .: .: . NP_005 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP : ..::.. ..: : :::.::. .. .:::: :: .::::..:.:::::::::::: NP_005 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK :::::::::::::::::::::::::::::::::::.::::::::::::.::::::::::: NP_005 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE :::.:::.::::::::::::::::.:::::::::::.::. :: : ::.:::::: :::: NP_005 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE ::::: ::::::::::::::.::::::::::::..:::. :.:::::::::::::..:. NP_005 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC :: .:::.:.::::.:::: :::::. ::.:.:::::.: : :. : ::..:: .:.:.: NP_005 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI ..:: :: .::::. .: :::.::.:...::::: ::::.::: :::.:.:::::::: NP_005 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK :::::::::.:. ::.:::.::.:::: :::::::.:::::.:::::: .:..::::. . NP_005 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-R 490 500 510 520 530 550 560 570 580 pF1KB9 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR ..:: :::::::::::.::. .. . :.: NP_005 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS 540 550 560 570 580 590 >>NP_892027 (OMIM: 137026) G protein-coupled receptor ki (578 aa) initn: 2593 init1: 2091 opt: 2632 Z-score: 1225.3 bits: 236.7 E(85289): 1.6e-61 Smith-Waterman score: 2632; 66.8% identity (86.4% similar) in 560 aa overlap (1-558:1-560) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ :::::::::..:::::.:: :...:.::::...: .: .::: ::: :.:.:: :::..: NP_892 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE :::: :::.:: :.: :.: . :::.::::::. :. :. :: .. . :.. .:: NP_892 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 VPRQLVTNCTQRL-EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ .: ..::.: : :..: : :.: ::..:.:: :: .: .: ::..:::::::::: NP_892 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE ::::::::.:::::::::::::::::::::::::::::.:::::::::::::::::.::: NP_892 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 KVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGL ::.::::::::::::::::::::::.:::::::::::..:. :: : ::::::::.:::: NP_892 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKN :::.::::::::::::::::::.:::::::::::...:::: ..::::::::::::::.: NP_892 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 ERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSL :.::::::::.::::.:::: :.:::.. :.:.: :::.. .:. :::::.:: .:.:. NP_892 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 CSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD : .:: :.:..:::::: .: ::.::.:: .::.:: :.:::::: :::.:.::::::: NP_892 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 IEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDW :::::.:::. :. .:.::: .:::: : :::::::.:. ::...: . ..: ::: NP_892 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK 490 500 510 520 530 540 540 550 560 570 580 pF1KB9 KGQPPAP-PKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR . . :. :..:.. ::: : NP_892 NIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC 550 560 570 >>XP_005269765 (OMIM: 600870) PREDICTED: G protein-coupl (558 aa) initn: 2666 init1: 2446 opt: 2557 Z-score: 1191.4 bits: 230.4 E(85289): 1.3e-59 Smith-Waterman score: 2578; 66.8% identity (83.2% similar) in 573 aa overlap (1-573:1-540) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ ::::::::::::::::: .::: :::..: XP_005 MELENIVANTVLLKARE--------------------------------DRDYCSLCDKQ 10 20 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE ::::::::.:: ::: : . :::.:::::::::.: :... ..:. .: .: . XP_005 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB9 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP : ..::.. ..: : :::.::. .. .:::: :: .::::..:.:::::::::::: XP_005 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB9 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK :::::::::::::::::::::::::::::::::::.::::::::::::.::::::::::: XP_005 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE :::.:::.::::::::::::::::.:::::::::::.::. :: : ::.:::::: :::: XP_005 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB9 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE ::::: ::::::::::::::.::::::::::::..:::. :.:::::::::::::..:. XP_005 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB9 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC :: .:::.:.::::.:::: :::::. ::.:.:::::.: : :. : ::..:: .:.:.: XP_005 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB9 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI ..:: :: .::::. .: :::.::.:...::::: ::::.::: :::.:.:::::::: XP_005 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB9 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK :::::::::.:. ::.:::.::.:::: :::::::.:::::.:::::: .:..::::. . XP_005 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-R 450 460 470 480 490 500 550 560 570 580 pF1KB9 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR ..:: :::::::::::.::. .. . :.: XP_005 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS 510 520 530 540 550 >>NP_001004057 (OMIM: 137026) G protein-coupled receptor (532 aa) initn: 2527 init1: 2025 opt: 2529 Z-score: 1178.9 bits: 228.0 E(85289): 6.3e-59 Smith-Waterman score: 2529; 68.9% identity (87.2% similar) in 524 aa overlap (1-519:1-524) 10 20 30 40 50 60 pF1KB9 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ :::::::::..:::::.:: :...:.::::...: .: .::: ::: :.:.:: :::..: NP_001 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE :::: :::.:: :.: :.: . :::.::::::. :. :. :: .. . :.. .:: NP_001 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 VPRQLVTNCTQRL-EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ .: ..::.: : :..: : :.: ::..:.:: :: .: .: ::..:::::::::: NP_001 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE ::::::::.:::::::::::::::::::::::::::::.:::::::::::::::::.::: NP_001 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 KVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGL ::.::::::::::::::::::::::.:::::::::::..:. :: : ::::::::.:::: NP_001 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKN :::.::::::::::::::::::.:::::::::::...:::: ..::::::::::::::.: NP_001 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 ERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSL :.::::::::.::::.:::: :.:::.. :.:.: :::.. .:. :::::.:: .:.:. NP_001 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 CSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD : .:: :.:..:::::: .: ::.::.:: .::.:: :.:::::: :::.:.::::::: NP_001 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 IEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNE----MVETECFQELNVFGLDGSVPP :::::.:::. :. .:.::: .:::: : :::::: :: .: NP_001 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEGCLTMVPSEKEVEPKQC 490 500 510 520 530 540 550 560 570 580 pF1KB9 DLDWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 589 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:58:19 2016 done: Sat Nov 5 11:58:21 2016 Total Scan time: 11.940 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]