FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9913, 285 aa 1>>>pF1KB9913 285 - 285 aa - 285 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9697+/-0.000309; mu= 13.7759+/- 0.019 mean_var=103.2426+/-20.178, 0's: 0 Z-trim(119.0): 4 B-trim: 24 in 1/57 Lambda= 0.126225 statistics sampled from 32481 (32485) to 32481 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.381), width: 16 Scan time: 5.710 The best scores are: opt bits E(85289) NP_060923 (OMIM: 609486) E2F-associated phosphopro ( 285) 1918 359.2 5.3e-99 XP_011535260 (OMIM: 609486) PREDICTED: E2F-associa ( 221) 1493 281.7 8.7e-76 XP_016876949 (OMIM: 609486) PREDICTED: E2F-associa ( 243) 1316 249.5 4.7e-66 NP_001305845 (OMIM: 609486) E2F-associated phospho ( 139) 767 149.3 3.8e-36 >>NP_060923 (OMIM: 609486) E2F-associated phosphoprotein (285 aa) initn: 1918 init1: 1918 opt: 1918 Z-score: 1898.4 bits: 359.2 E(85289): 5.3e-99 Smith-Waterman score: 1918; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285) 10 20 30 40 50 60 pF1KB9 MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQRRGYHGLGPQRSRQQQPVPNSDAVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQRRGYHGLGPQRSRQQQPVPNSDAVLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 CPACMTTLCLDCQRHESYKTQYRAMFVMNCSINKEEVLRYKASENRKKRRVHKKMRSNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 CPACMTTLCLDCQRHESYKTQYRAMFVMNCSINKEEVLRYKASENRKKRRVHKKMRSNRE 190 200 210 220 230 240 250 260 270 280 pF1KB9 DAAEKAETDVEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS ::::::::::::::::::::::::::::::::::::::::::::: NP_060 DAAEKAETDVEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS 250 260 270 280 >>XP_011535260 (OMIM: 609486) PREDICTED: E2F-associated (221 aa) initn: 1493 init1: 1493 opt: 1493 Z-score: 1481.6 bits: 281.7 E(85289): 8.7e-76 Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 221 aa overlap (65-285:1-221) 40 50 60 70 80 90 pF1KB9 HGTPDQKRKLIRECLTGESESSSEDEFEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKV :::::::::::::::::::::::::::::: XP_011 MEAELNSTMKTMEDKLSSLGTGSSSGNGKV 10 20 30 100 110 120 130 140 150 pF1KB9 ATAPTRYYDDIYFDSDSEDEDRAVQVTKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATAPTRYYDDIYFDSDSEDEDRAVQVTKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB9 RRGYHGLGPQRSRQQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRGYHGLGPQRSRQQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSINK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB9 EEVLRYKASENRKKRRVHKKMRSNREDAAEKAETDVEEIYHPVMCTECSTEVAVYDKDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEVLRYKASENRKKRRVHKKMRSNREDAAEKAETDVEEIYHPVMCTECSTEVAVYDKDEV 160 170 180 190 200 210 280 pF1KB9 FHFFNVLASHS ::::::::::: XP_011 FHFFNVLASHS 220 >>XP_016876949 (OMIM: 609486) PREDICTED: E2F-associated (243 aa) initn: 1460 init1: 1316 opt: 1316 Z-score: 1306.9 bits: 249.5 E(85289): 4.7e-66 Smith-Waterman score: 1316; 99.5% identity (100.0% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KB9 MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQRRGYHGLGPQRSRQQQPVPNSDAVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQRRGYHGLGPQRSRQQQPVPNSDAVLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 CPACMTTLCLDCQRHESYKTQYRAMFVMNCSINKEEVLRYKASENRKKRRVHKKMRSNRE ::::::::::::::. XP_016 CPACMTTLCLDCQRQTVAEWINKQDSTICCLEETCFTCKDTWTEHEWEKIFHAAGNQYRN 190 200 210 220 230 240 >>NP_001305845 (OMIM: 609486) E2F-associated phosphoprot (139 aa) initn: 767 init1: 767 opt: 767 Z-score: 769.8 bits: 149.3 E(85289): 3.8e-36 Smith-Waterman score: 767; 100.0% identity (100.0% similar) in 118 aa overlap (1-118:1-118) 10 20 30 40 50 60 pF1KB9 MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVTM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQRRGYHGLGPQRSRQQQPVPNSDAVLN NP_001 VWDHRDHVNNSLFQIVMLS 130 285 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:49:06 2016 done: Fri Nov 4 09:49:07 2016 Total Scan time: 5.710 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]