FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9923, 342 aa 1>>>pF1KB9923 342 - 342 aa - 342 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8461+/-0.000303; mu= 0.5898+/- 0.019 mean_var=186.3539+/-38.001, 0's: 0 Z-trim(123.4): 23 B-trim: 38 in 1/52 Lambda= 0.093952 statistics sampled from 43081 (43104) to 43081 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.505), width: 16 Scan time: 8.470 The best scores are: opt bits E(85289) NP_037438 (OMIM: 605964) sorting nexin-15 isoform ( 342) 2297 322.9 6.2e-88 NP_680086 (OMIM: 605964) sorting nexin-15 isoform ( 256) 1504 215.4 1.1e-55 >>NP_037438 (OMIM: 605964) sorting nexin-15 isoform A [H (342 aa) initn: 2297 init1: 2297 opt: 2297 Z-score: 1699.7 bits: 322.9 E(85289): 6.2e-88 Smith-Waterman score: 2297; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB9 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVH 250 260 270 280 290 300 310 320 330 340 pF1KB9 VLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP :::::::::::::::::::::::::::::::::::::::::: NP_037 VLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP 310 320 330 340 >>NP_680086 (OMIM: 605964) sorting nexin-15 isoform B [H (256 aa) initn: 1708 init1: 1500 opt: 1504 Z-score: 1120.7 bits: 215.4 E(85289): 1.1e-55 Smith-Waterman score: 1540; 74.6% identity (74.9% similar) in 342 aa overlap (1-342:1-256) 10 20 30 40 50 60 pF1KB9 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVE ::::::::::::::::::::::::::::::::::::::::: NP_680 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE------------------- 190 200 210 220 250 260 270 280 290 300 pF1KB9 SARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVH NP_680 ------------------------------------------------------------ 310 320 330 340 pF1KB9 VLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP .:::::::::::::::::::::::::::::::::: NP_680 -------GDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP 230 240 250 342 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:50:07 2016 done: Sat Nov 5 14:50:08 2016 Total Scan time: 8.470 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]