Result of FASTA (omim) for
pF1KB9947
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9947, 531 aa
1>>>pF1KB9947 531 - 531 aa - 531 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0660+/-0.000433; mu= 19.5101+/- 0.027
mean_var=68.3804+/-13.737, 0's: 0 Z-trim(108.8): 36 B-trim: 713 in 1/52
Lambda= 0.155099
statistics sampled from 16851 (16880) to 16851 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.198), width: 16
Scan time: 9.240
The best scores are: opt bits E(85289)
NP_002645 (OMIM: 179050) pyruvate kinase PKM isofo ( 531) 3465 785.1 0
XP_005254502 (OMIM: 179050) PREDICTED: pyruvate ki ( 531) 3465 785.1 0
XP_011519972 (OMIM: 179050) PREDICTED: pyruvate ki ( 566) 3465 785.1 0
XP_005254500 (OMIM: 179050) PREDICTED: pyruvate ki ( 591) 3465 785.2 0
XP_006720633 (OMIM: 179050) PREDICTED: pyruvate ki ( 605) 3465 785.2 0
XP_016877802 (OMIM: 179050) PREDICTED: pyruvate ki ( 531) 3325 753.8 2.9e-217
NP_872271 (OMIM: 179050) pyruvate kinase PKM isofo ( 531) 3325 753.8 2.9e-217
NP_872270 (OMIM: 179050) pyruvate kinase PKM isofo ( 531) 3325 753.8 2.9e-217
NP_001193728 (OMIM: 179050) pyruvate kinase PKM is ( 536) 3325 753.8 2.9e-217
NP_001303247 (OMIM: 179050) pyruvate kinase PKM is ( 566) 3325 753.8 3.1e-217
NP_001193725 (OMIM: 179050) pyruvate kinase PKM is ( 605) 3325 753.8 3.2e-217
NP_001193727 (OMIM: 179050) pyruvate kinase PKM is ( 516) 2923 663.8 3.4e-190
NP_001193726 (OMIM: 179050) pyruvate kinase PKM is ( 457) 2633 598.9 1.1e-170
NP_870986 (OMIM: 102900,266200,609712) pyruvate ki ( 543) 2547 579.7 7.5e-165
NP_000289 (OMIM: 102900,266200,609712) pyruvate ki ( 574) 2547 579.7 7.9e-165
XP_006711449 (OMIM: 102900,266200,609712) PREDICTE ( 510) 2484 565.6 1.3e-160
XP_011507942 (OMIM: 102900,266200,609712) PREDICTE ( 510) 2484 565.6 1.3e-160
XP_016856982 (OMIM: 102900,266200,609712) PREDICTE ( 383) 1557 358.1 2.8e-98
>>NP_002645 (OMIM: 179050) pyruvate kinase PKM isoform a (531 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 4190.8 bits: 785.1 E(85289): 0
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:1-531)
10 20 30 40 50 60
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
490 500 510 520 530
>>XP_005254502 (OMIM: 179050) PREDICTED: pyruvate kinase (531 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 4190.8 bits: 785.1 E(85289): 0
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:1-531)
10 20 30 40 50 60
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
490 500 510 520 530
>>XP_011519972 (OMIM: 179050) PREDICTED: pyruvate kinase (566 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 4190.4 bits: 785.1 E(85289): 0
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:36-566)
10 20 30
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHM
::::::::::::::::::::::::::::::
XP_011 ERGERLLTPGACSSEVPSAVPSRSGGTSAAMSKPHSEAGTAFIQTQQLHAAMADTFLEHM
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB9 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB9 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
490 500 510 520 530 540
520 530
pF1KB9 VLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::
XP_011 VLTGWRPGSGFTNTMRVVPVP
550 560
>>XP_005254500 (OMIM: 179050) PREDICTED: pyruvate kinase (591 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 4190.2 bits: 785.2 E(85289): 0
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:61-591)
10 20 30
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHM
::::::::::::::::::::::::::::::
XP_005 LVRPRSHPEPKGEHYVTGSPTPENQRTSAAMSKPHSEAGTAFIQTQQLHAAMADTFLEHM
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB9 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB9 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB9 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB9 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB9 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB9 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
400 410 420 430 440 450
400 410 420 430 440 450
pF1KB9 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
460 470 480 490 500 510
460 470 480 490 500 510
pF1KB9 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
520 530 540 550 560 570
520 530
pF1KB9 VLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::
XP_005 VLTGWRPGSGFTNTMRVVPVP
580 590
>>XP_006720633 (OMIM: 179050) PREDICTED: pyruvate kinase (605 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 4190.0 bits: 785.2 E(85289): 0
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:75-605)
10 20 30
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHM
::::::::::::::::::::::::::::::
XP_006 LVRPRSHPEPKGEHYVTGSPTPENQRTSAAMSKPHSEAGTAFIQTQQLHAAMADTFLEHM
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB9 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB9 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB9 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB9 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
290 300 310 320 330 340
280 290 300 310 320 330
pF1KB9 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
350 360 370 380 390 400
340 350 360 370 380 390
pF1KB9 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
410 420 430 440 450 460
400 410 420 430 440 450
pF1KB9 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
470 480 490 500 510 520
460 470 480 490 500 510
pF1KB9 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
530 540 550 560 570 580
520 530
pF1KB9 VLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::
XP_006 VLTGWRPGSGFTNTMRVVPVP
590 600
>>XP_016877802 (OMIM: 179050) PREDICTED: pyruvate kinase (531 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 4021.5 bits: 753.8 E(85289): 2.9e-217
Smith-Waterman score: 3325; 95.9% identity (98.3% similar) in 531 aa overlap (1-531:1-531)
10 20 30 40 50 60
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
::::::::::::::::::::::::::::..: .::::: : . ..: :: :.:.::::
XP_016 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
.:: ..:.::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
490 500 510 520 530
>>NP_872271 (OMIM: 179050) pyruvate kinase PKM isoform b (531 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 4021.5 bits: 753.8 E(85289): 2.9e-217
Smith-Waterman score: 3325; 95.9% identity (98.3% similar) in 531 aa overlap (1-531:1-531)
10 20 30 40 50 60
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
::::::::::::::::::::::::::::..: .::::: : . ..: :: :.:.::::
NP_872 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
.:: ..:.::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_872 YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
490 500 510 520 530
>>NP_872270 (OMIM: 179050) pyruvate kinase PKM isoform b (531 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 4021.5 bits: 753.8 E(85289): 2.9e-217
Smith-Waterman score: 3325; 95.9% identity (98.3% similar) in 531 aa overlap (1-531:1-531)
10 20 30 40 50 60
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
::::::::::::::::::::::::::::..: .::::: : . ..: :: :.:.::::
NP_872 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
.:: ..:.::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_872 YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
490 500 510 520 530
>>NP_001193728 (OMIM: 179050) pyruvate kinase PKM isofor (536 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 4021.5 bits: 753.8 E(85289): 2.9e-217
Smith-Waterman score: 3325; 95.9% identity (98.3% similar) in 531 aa overlap (1-531:6-536)
10 20 30 40 50
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSAAMSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 RSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 GPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 VDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 DVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 DLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 ADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVG
:::::::::::::::::::::::::::::::::..: .::::: : . ..: :: :.:
NP_001 ADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 AVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCK
.::::.:: ..:.::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 SVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 DPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
490 500 510 520 530
>>NP_001303247 (OMIM: 179050) pyruvate kinase PKM isofor (566 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 4021.1 bits: 753.8 E(85289): 3.1e-217
Smith-Waterman score: 3325; 95.9% identity (98.3% similar) in 531 aa overlap (1-531:36-566)
10 20 30
pF1KB9 MSKPHSEAGTAFIQTQQLHAAMADTFLEHM
::::::::::::::::::::::::::::::
NP_001 ERGERLLTPGACSSEVPSAVPSRSGGTSAAMSKPHSEAGTAFIQTQQLHAAMADTFLEHM
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYME
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQM
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB9 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::..
NP_001 LESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMF
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB9 HLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPI
: .::::: : . ..: :: :.:.::::.:: ..:.::::.:::::::::::::::::
NP_001 HRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPI
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVI
490 500 510 520 530 540
520 530
pF1KB9 VLTGWRPGSGFTNTMRVVPVP
:::::::::::::::::::::
NP_001 VLTGWRPGSGFTNTMRVVPVP
550 560
531 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:58:06 2016 done: Sat Nov 5 14:58:08 2016
Total Scan time: 9.240 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]