Result of FASTA (omim) for
pF1KB9950
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9950, 675 aa
1>>>pF1KB9950 675 - 675 aa - 675 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.2021+/-0.000644; mu= -31.2863+/- 0.038
mean_var=746.5959+/-167.149, 0's: 0 Z-trim(114.0): 1407 B-trim: 1387 in 1/55
Lambda= 0.046939
statistics sampled from 21799 (23681) to 21799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.278), width: 16
Scan time: 9.680
The best scores are: opt bits E(85289)
NP_975010 (OMIM: 300101) cytoplasmic tyrosine-prot ( 675) 4562 325.8 3.2e-88
NP_001712 (OMIM: 300101) cytoplasmic tyrosine-prot ( 675) 4562 325.8 3.2e-88
NP_001307795 (OMIM: 300101) cytoplasmic tyrosine-p ( 674) 4545 324.7 7.1e-88
XP_016885241 (OMIM: 300101) PREDICTED: cytoplasmic ( 477) 3101 226.7 1.5e-58
NP_000052 (OMIM: 300300,300755,307200) tyrosine-pr ( 659) 1722 133.5 2.5e-30
NP_001274273 (OMIM: 300300,300755,307200) tyrosine ( 693) 1722 133.5 2.6e-30
XP_016864058 (OMIM: 600583) PREDICTED: tyrosine-pr ( 515) 1575 123.4 2.1e-27
XP_011512039 (OMIM: 600583) PREDICTED: tyrosine-pr ( 595) 1575 123.5 2.3e-27
NP_003206 (OMIM: 600583) tyrosine-protein kinase T ( 631) 1575 123.5 2.4e-27
XP_016864070 (OMIM: 600058) PREDICTED: tyrosine-pr ( 502) 1568 123.0 2.8e-27
NP_003319 (OMIM: 600058) tyrosine-protein kinase T ( 527) 1568 123.0 2.9e-27
XP_016864069 (OMIM: 600058) PREDICTED: tyrosine-pr ( 530) 1568 123.0 2.9e-27
XP_011512049 (OMIM: 600058) PREDICTED: tyrosine-pr ( 508) 1530 120.4 1.7e-26
XP_016864932 (OMIM: 186973,613011) PREDICTED: tyro ( 495) 1493 117.9 9.4e-26
NP_005537 (OMIM: 186973,613011) tyrosine-protein k ( 620) 1493 118.0 1.1e-25
XP_016864071 (OMIM: 600058) PREDICTED: tyrosine-pr ( 338) 1362 108.8 3.4e-23
XP_011512050 (OMIM: 600058) PREDICTED: tyrosine-pr ( 289) 1210 98.5 3.8e-20
NP_005148 (OMIM: 189980) tyrosine-protein kinase A (1130) 1019 86.1 7.8e-16
NP_009297 (OMIM: 189980) tyrosine-protein kinase A (1149) 1019 86.1 7.9e-16
NP_001129473 (OMIM: 164690) Abelson tyrosine-prote ( 542) 991 83.9 1.7e-15
NP_001036236 (OMIM: 153390,615758) tyrosine-protei ( 509) 983 83.3 2.4e-15
NP_005347 (OMIM: 153390,615758) tyrosine-protein k ( 509) 983 83.3 2.4e-15
NP_001161711 (OMIM: 164690) Abelson tyrosine-prote (1043) 991 84.2 2.7e-15
NP_001161710 (OMIM: 164690) Abelson tyrosine-prote (1058) 991 84.2 2.8e-15
NP_001129472 (OMIM: 164690) Abelson tyrosine-prote (1064) 991 84.2 2.8e-15
NP_001161709 (OMIM: 164690) Abelson tyrosine-prote (1079) 991 84.2 2.8e-15
XP_005245145 (OMIM: 164690) PREDICTED: Abelson tyr (1146) 991 84.2 2.9e-15
NP_001161708 (OMIM: 164690) Abelson tyrosine-prote (1161) 991 84.2 3e-15
NP_005149 (OMIM: 164690) Abelson tyrosine-protein (1167) 991 84.2 3e-15
NP_009298 (OMIM: 164690) Abelson tyrosine-protein (1182) 991 84.2 3e-15
XP_016856524 (OMIM: 164690) PREDICTED: Abelson tyr (1182) 991 84.2 3e-15
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
XP_011533955 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505) 972 82.6 4e-15
XP_011533956 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
XP_011533957 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
XP_005266938 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
XP_005266937 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
XP_005266939 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 972 82.6 4e-15
XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 966 82.2 5.5e-15
XP_016866142 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 966 82.2 5.5e-15
XP_016866140 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 966 82.2 5.5e-15
XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 966 82.2 5.5e-15
NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537) 966 82.2 5.5e-15
XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 966 82.2 5.5e-15
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392) 956 81.4 7e-15
NP_938033 (OMIM: 114500,190090,616937) proto-oncog ( 536) 957 81.6 8.4e-15
NP_005408 (OMIM: 114500,190090,616937) proto-oncog ( 536) 957 81.6 8.4e-15
XP_011527315 (OMIM: 114500,190090,616937) PREDICTE ( 536) 957 81.6 8.4e-15
XP_016883515 (OMIM: 114500,190090,616937) PREDICTE ( 542) 956 81.5 8.9e-15
>>NP_975010 (OMIM: 300101) cytoplasmic tyrosine-protein (675 aa)
initn: 4562 init1: 4562 opt: 4562 Z-score: 1704.8 bits: 325.8 E(85289): 3.2e-88
Smith-Waterman score: 4562; 100.0% identity (100.0% similar) in 675 aa overlap (1-675:1-675)
10 20 30 40 50 60
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 NCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 NCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 LMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_975 LMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQ
610 620 630 640 650 660
670
pF1KB9 QLLSSIEPLREKDKH
:::::::::::::::
NP_975 QLLSSIEPLREKDKH
670
>>NP_001712 (OMIM: 300101) cytoplasmic tyrosine-protein (675 aa)
initn: 4562 init1: 4562 opt: 4562 Z-score: 1704.8 bits: 325.8 E(85289): 3.2e-88
Smith-Waterman score: 4562; 100.0% identity (100.0% similar) in 675 aa overlap (1-675:1-675)
10 20 30 40 50 60
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 NCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 LMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQ
610 620 630 640 650 660
670
pF1KB9 QLLSSIEPLREKDKH
:::::::::::::::
NP_001 QLLSSIEPLREKDKH
670
>>NP_001307795 (OMIM: 300101) cytoplasmic tyrosine-prote (674 aa)
initn: 2869 init1: 2869 opt: 4545 Z-score: 1698.6 bits: 324.7 E(85289): 7.1e-88
Smith-Waterman score: 4545; 99.9% identity (99.9% similar) in 675 aa overlap (1-675:1-674)
10 20 30 40 50 60
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDWWQVRKLKSSSS-EDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
250 260 270 280 290
310 320 330 340 350 360
pF1KB9 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB9 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB9 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB9 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB9 NCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGI
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB9 LMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQ
600 610 620 630 640 650
670
pF1KB9 QLLSSIEPLREKDKH
:::::::::::::::
NP_001 QLLSSIEPLREKDKH
660 670
>>XP_016885241 (OMIM: 300101) PREDICTED: cytoplasmic tyr (477 aa)
initn: 3205 init1: 3101 opt: 3101 Z-score: 1172.0 bits: 226.7 E(85289): 1.5e-58
Smith-Waterman score: 3101; 99.8% identity (99.8% similar) in 467 aa overlap (1-467:1-467)
10 20 30 40 50 60
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCS
::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 KELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMLLVTAWWTEISV
430 440 450 460 470
490 500 510 520 530 540
pF1KB9 KEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAAR
>>NP_000052 (OMIM: 300300,300755,307200) tyrosine-protei (659 aa)
initn: 2185 init1: 1667 opt: 1722 Z-score: 665.5 bits: 133.5 E(85289): 2.5e-30
Smith-Waterman score: 2189; 48.6% identity (74.5% similar) in 689 aa overlap (6-666:5-651)
10 20 30 40 50
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYD--KMKRGSRKGSIEIK
::: ..::::::::: :: :.:.:::.:: .::::::: . .:::.::::...
NP_000 MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVE
10 20 30 40 50
60 70 80 90
pF1KB9 KIRCVEKVNLEEQTPVERQ---------------------YPFQIVYKDGLLYVYASNEE
:: ::: : :.. : ::: ::::.:: .: :::.. .::
NP_000 KITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEE
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB9 SRSQWLKALQKEIRGNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY-ANLHTAV
:..:.. :.. :: : :. ::: :..::..:::.:. : : :: . : ..:. .
NP_000 LRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 NEEKHRVPTFP----DRVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTS
...: . : : :..:: : .: :: :.. : . : .:
NP_000 SHRKTKKPLPPTPEEDQILKKP--LPPEPAAAPVSTSELKKV----VALYDYMP------
180 190 200 210 220
220 230 240 250 260 270
pF1KB9 LAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTT
...:. .. .. : .. . ..: ::..: ..: .: .
NP_000 ---MNANDLQLRKGDEYFILE---ESNLP-WWRAR------------DKNGQEGYI----
230 240 250 260
280 290 300 310 320 330
pF1KB9 SKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTV
: . .: :.... :.:.. ...:::.::::.:.::::.:.::.::..: :::
NP_000 -------PSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTV
270 280 290 300 310
340 350 360 370 380 390
pF1KB9 SLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPV
:.:.:...: .:...:: : .. ... ::::.. :..::.::.::::::::.:.::..::
NP_000 SVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPV
320 330 340 350 360 370
400 410 420 430 440 450
pF1KB9 STKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSM
: . ...:....:: : ::. ...:.:::::.::::::. :::.::::::.::::::::
NP_000 SQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSM
380 390 400 410 420 430
460 470 480 490 500 510
pF1KB9 SEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQ
:::::..::..::.::: :::..::::.:. ::.:.:::..::::::::: . .. .:
NP_000 SEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ
440 450 460 470 480 490
520 530 540 550 560 570
pF1KB9 LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGT
::::: ::::.: .:::.::.:::::::::::. . :::::::..::::::.:.::::.
NP_000 LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGS
500 510 520 530 540 550
580 590 600 610 620 630
pF1KB9 KFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLY
::::.:: :::. : :.:::::.::::.::::..::::.::. . ::... ...:: :::
NP_000 KFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY
560 570 580 590 600 610
640 650 660 670
pF1KB9 RPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKDKH
::::::. .: :::::::: ..::::. :::.:
NP_000 RPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
620 630 640 650
>>NP_001274273 (OMIM: 300300,300755,307200) tyrosine-pro (693 aa)
initn: 2185 init1: 1667 opt: 1722 Z-score: 665.3 bits: 133.5 E(85289): 2.6e-30
Smith-Waterman score: 2189; 48.6% identity (74.5% similar) in 689 aa overlap (6-666:39-685)
10 20 30
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTK
::: ..::::::::: :: :.:.:::.::
NP_001 MVIGCPLCGRHCSGGEHTGELQKEEAMAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTV
10 20 30 40 50 60
40 50 60 70
pF1KB9 TNLSYYEYD--KMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQ----------------
.::::::: . .:::.::::...:: ::: : :.. : :::
NP_001 HKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISI
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB9 -----YPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKYHSGFFVDGKFLC
::::.:: .: :::.. .:: :..:.. :.. :: : :. ::: :..::..::
NP_001 IERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLC
130 140 150 160 170 180
140 150 160 170 180
pF1KB9 CQQSCKAAPGCTLWEAY-ANLHTAVNEEKHRVPTFP----DRVLKIPRAVPVLKMDAPSS
:.:. : : :: . : ..:. . ...: . : : :..:: : .: :: :
NP_001 CSQTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKP--LPPEPAAAPVS
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB9 STTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVR
.. : . : .: ...:. .. .. : .. . ..: ::..:
NP_001 TSELKKV----VALYDYMP---------MNANDLQLRKGDEYFILE---ESNLP-WWRAR
250 260 270 280
250 260 270 280 290 300
pF1KB9 KLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSE
..: .: . : . .: :.... :.:.. ...:::.:
NP_001 ------------DKNGQEGYI-----------PSNYVTEAEDSIEMYEWYSKHMTRSQAE
290 300 310 320
310 320 330 340 350 360
pF1KB9 QLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCF
:::.:.::::.:.::.::..: ::::.:.:...: .:...:: : .. ... ::::.. :
NP_001 QLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLF
330 340 350 360 370 380
370 380 390 400 410 420
pF1KB9 DSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQ
..::.::.::::::::.:.::..::: . ...:....:: : ::. ...:.:::::.::
NP_001 STIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQ
390 400 410 420 430 440
430 440 450 460 470 480
pF1KB9 FGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYI
::::. :::.::::::.:::::::::::::..::..::.::: :::..::::.:. ::.:
NP_001 FGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFI
450 460 470 480 490 500
490 500 510 520 530 540
pF1KB9 VTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRD
.:::..::::::::: . .. .:::::: ::::.: .:::.::.:::::::::::. .
NP_001 ITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQ
510 520 530 540 550 560
550 560 570 580 590 600
pF1KB9 LCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFS
:::::::..::::::.:.::::.::::.:: :::. : :.:::::.::::.::::..:
NP_001 GVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYS
570 580 590 600 610 620
610 620 630 640 650 660
pF1KB9 LGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIE
:::.::. . ::... ...:: :::::::::. .: :::::::: ..::::. :::.:
NP_001 LGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNIL
630 640 650 660 670 680
670
pF1KB9 PLREKDKH
NP_001 DVMDEES
690
>>XP_016864058 (OMIM: 600583) PREDICTED: tyrosine-protei (515 aa)
initn: 1701 init1: 1337 opt: 1575 Z-score: 613.1 bits: 123.4 E(85289): 2.1e-27
Smith-Waterman score: 1659; 45.3% identity (73.5% similar) in 558 aa overlap (117-671:1-508)
90 100 110 120 130 140
pF1KB9 GLLYVYASNEESRSQWLKALQKEIRGNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLW
..::: :..::.. ::.:. : ::::
XP_016 MIKYHPKFWTDGSYQCCRQTEKLAPGC---
10 20
150 160 170 180 190 200
pF1KB9 EAYANLHTAVNEEKHRVPTFPD-RVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQ
: : ..... .. .: :. . . : .:. . : : ..:.:: .. ...
XP_016 EKYNLFESSI---RKALPPAPETKKRRPPPPIPLEEEDN-SEEIVVAMYDFQAAEGH---
30 40 50 60 70 80
210 220 230 240 250 260
pF1KB9 PPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKE
. .. .: . .. ..: ::..: .. ..: ::
XP_016 --------------DLRLERGQEYLILE---KNDV-HWWRAR---DKYGNEGYIPSN---
90 100 110
270 280 290 300 310 320
pF1KB9 RNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSS
..:.: : .:::.:.:. :..::..:::::.. :::.::::.::
XP_016 ----YVTGKKS------------NNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSS
120 130 140 150 160
330 340 350 360 370 380
pF1KB9 QVGMYTVSLFSKAVNDKKGTVKHYHVH--TNAENKLYLAENYCFDSIPKLIHYHQHNSAG
: :.:::::..: .. .. .:::.. :.. .: ::::.. : :::..:.::.::.::
XP_016 QPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAG
170 180 190 200 210 220
390 400 410 420 430 440
pF1KB9 MITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVA
..::::.:::.:....: ..... ::.. :.:...::::: ::::.::::..:: ::
XP_016 LVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVA
230 240 250 260 270 280
450 460 470 480 490 500
pF1KB9 VKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRS
.: :.::.: :..:..::..::::.:::::..::::... :::::::.. :::::.::.
XP_016 IKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQ
290 300 310 320 330 340
510 520 530 540 550 560
pF1KB9 HGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLD
. . . :: :: :::::: .:: ..:::::::::::::.. ::::::::.:::::
XP_016 RQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLD
350 360 370 380 390 400
570 580 590 600 610 620
pF1KB9 DQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVL
:::.:: :.:::::: ::::.: ..:::::::.::.::::::. :..:.. : : .::
XP_016 DQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVT
410 420 430 440 450 460
630 640 650 660 670
pF1KB9 KVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKDKH
:..:::::.:.:::. .:..: ::.: :: ::.:..:: .:. : :
XP_016 MVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEETFGR
470 480 490 500 510
>>XP_011512039 (OMIM: 600583) PREDICTED: tyrosine-protei (595 aa)
initn: 1872 init1: 1337 opt: 1575 Z-score: 612.3 bits: 123.5 E(85289): 2.3e-27
Smith-Waterman score: 1855; 44.5% identity (73.8% similar) in 629 aa overlap (47-671:10-588)
20 30 40 50 60 70
pF1KB9 QKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQT-PVE
.. ::: :...::.::: :. .. . : .
XP_011 MKSGNSIHHQKKYRKGFIDVSKIKCVEIVKNDDGVIPCQ
10 20 30
80 90 100 110 120 130
pF1KB9 RQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKYHSGFFVDGKFLCCQQ
.::::.:. . ::..: . .::. :.: :..::..: ....::: :..::.. ::.:
XP_011 NKYPFQVVHDANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIKYHPKFWTDGSYQCCRQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB9 SCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPD-RVLKIPRAVPVLKMDAPSSSTTLAQY
. : :::: : : ..... .. .: :. . . : .:. . : : ..:.:
XP_011 TEKLAPGC---EKYNLFESSI---RKALPPAPETKKRRPPPPIPLEEEDN-SEEIVVAMY
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB9 DNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSS
: .. ... . .. .: . .. ..: ::..: .. .
XP_011 DFQAAEGH-----------------DLRLERGQEYLILE---KNDV-HWWRAR---DKYG
160 170 180
260 270 280 290 300 310
pF1KB9 SEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKG
.: :: ..:.: : .:::.:.:. :..::..:::::..
XP_011 NEGYIPSN-------YVTGKKS------------NNLDQYEWYCRNMNRSKAEQLLRSED
190 200 210 220
320 330 340 350 360 370
pF1KB9 KEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVH--TNAENKLYLAENYCFDSIPK
:::.::::.::: :.:::::..: .. .. .:::.. :.. .: ::::.. : :::.
XP_011 KEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKKYYLAEKHAFGSIPE
230 240 250 260 270 280
380 390 400 410 420 430
pF1KB9 LIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQ
.:.::.::.::..::::.:::.:....: ..... ::.. :.:...::::: ::::.
XP_011 IIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVR
290 300 310 320 330 340
440 450 460 470 480 490
pF1KB9 LGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYI
::::..:: ::.: :.::.: :..:..::..::::.:::::..::::... :::::::..
XP_011 LGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFM
350 360 370 380 390 400
500 510 520 530 540 550
pF1KB9 SNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKV
:::::.::.. . . :: :: :::::: .:: ..:::::::::::::.. :::
XP_011 ERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKV
410 420 430 440 450 460
560 570 580 590 600 610
pF1KB9 SDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQP
:::::.::::::::.:: :.:::::: ::::.: ..:::::::.::.::::::. :..:
XP_011 SDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMP
470 480 490 500 510 520
620 630 640 650 660 670
pF1KB9 YDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREK
.. : : .:: :..:::::.:.:::. .:..: ::.: :: ::.:..:: .:. : :
XP_011 FEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVEC
530 540 550 560 570 580
pF1KB9 DKH
XP_011 EETFGR
590
>>NP_003206 (OMIM: 600583) tyrosine-protein kinase Tec [ (631 aa)
initn: 1974 init1: 1337 opt: 1575 Z-score: 612.0 bits: 123.5 E(85289): 2.4e-27
Smith-Waterman score: 2040; 46.1% identity (74.5% similar) in 675 aa overlap (1-671:1-624)
10 20 30 40 50 60
pF1KB9 MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKI
:. ..::::.:.:::::::: :: :::::::::::. :.::: . .. ::: :...::
NP_003 MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYE-GRAEKKYRKGFIDVSKI
10 20 30 40 50
70 80 90 100 110
pF1KB9 RCVEKVNLEEQT-PVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVK
.::: :. .. . : . .::::.:. . ::..: . .::. :.: :..::..: ....:
NP_003 KCVEIVKNDDGVIPCQNKYPFQVVHDANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 YHSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPD-RVLKIPRAVP
:: :..::.. ::.:. : :::: : : ..... .. .: :. . . : .:
NP_003 YHPKFWTDGSYQCCRQTEKLAPGC---EKYNLFESSI---RKALPPAPETKKRRPPPPIP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 VLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPRE
. . : : ..:.:: .. ... . .. .: . .. ..
NP_003 LEEEDN-SEEIVVAMYDFQAAEGH-----------------DLRLERGQEYLILE---KN
180 190 200 210
240 250 260 270 280 290
pF1KB9 DFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFA
: ::..: .. ..: :: ..:.: : .:::.:.:.
NP_003 DV-HWWRAR---DKYGNEGYIPSN-------YVTGKKS------------NNLDQYEWYC
220 230 240
300 310 320 330 340 350
pF1KB9 GNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVH--TNAE
:..::..:::::.. :::.::::.::: :.:::::..: .. .. .:::.. :..
NP_003 RNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSP
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB9 NKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREE
.: ::::.. : :::..:.::.::.::..::::.:::.:....: ..... ::.. :
NP_003 KKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSE
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB9 ITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFY
.:...::::: ::::.::::..:: ::.: :.::.: :..:..::..::::.:::::..:
NP_003 LTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLY
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB9 GVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRD
:::... :::::::.. :::::.::.. . . :: :: :::::: .:: ..:::::
NP_003 GVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRD
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB9 LAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVW
::::::::.. ::::::::.::::::::.:: :.:::::: ::::.: ..:::::::
NP_003 LAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVW
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB9 AFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKR
.::.::::::. :..:.. : : .:: :..:::::.:.:::. .:..: ::.: :: :
NP_003 SFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGR
550 560 570 580 590 600
660 670
pF1KB9 PTFQQLLSSIEPLREKDKH
:.:..:: .:. : :
NP_003 PSFEDLLRTIDELVECEETFGR
610 620 630
>>XP_016864070 (OMIM: 600058) PREDICTED: tyrosine-protei (502 aa)
initn: 1573 init1: 1546 opt: 1568 Z-score: 610.7 bits: 123.0 E(85289): 2.8e-27
Smith-Waterman score: 1568; 48.8% identity (74.1% similar) in 482 aa overlap (191-671:25-500)
170 180 190 200 210 220
pF1KB9 HRVPTFPDRVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNS
:.: .:....: : ::. : .
XP_016 MRTQISLSTDEELPEKYTQRRRPWLSQLSNKKQSNTGRVQPSKRKPLPPLPPSE
10 20 30 40 50
230 240 250 260 270 280
pF1KB9 KKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFP
: . ....::: : .:. . : : :. . . : :
XP_016 VAEEKIQVKALYDFLPRE--PCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLI----P
60 70 80 90 100
290 300 310 320 330
pF1KB9 ESSSSEEE-ENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAV
. .:.. ::. :.:. ::.:.:.:.::::..:::::.::.: ..: ::.:.: :
XP_016 SNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGAR
110 120 130 140 150 160
340 350 360 370 380 390
pF1KB9 NDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKV
. ....:::... : .. :.:: . :.:::.:: :::::.::..::::.::. .. .
XP_016 RSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCL
170 180 190 200 210 220
400 410 420 430 440 450
pF1KB9 PDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQ
: ..... ::. :....::.::::::::.::.:... .::.: :.::::::..:..
XP_016 PATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIE
230 240 250 260 270 280
460 470 480 490 500 510
pF1KB9 EAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYD
::..:::::: :::..:::: .. :.:::::.. ::::::::: . :. .:: .: :
XP_016 EAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQD
290 300 310 320 330 340
520 530 540 550 560 570
pF1KB9 VCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWS
.:::: .:: . .::::::::::::. ::.::::::::::::.:::: :.:::.:::
XP_016 ICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWS
350 360 370 380 390 400
580 590 600 610 620 630
pF1KB9 APEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASD
:::: . :::::::::.::.::::::. ::.:.. .: ::: .:.: ::::::::
XP_016 PPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPM
410 420 430 440 450 460
640 650 660 670
pF1KB9 TIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKDKH
.::..::::::: :: :::: .:: .. . :
XP_016 SIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
470 480 490 500
675 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:54:17 2016 done: Sat Nov 5 07:54:19 2016
Total Scan time: 9.680 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]