FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9951, 535 aa 1>>>pF1KB9951 535 - 535 aa - 535 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8158+/-0.000382; mu= 8.9589+/- 0.024 mean_var=288.7079+/-65.104, 0's: 0 Z-trim(119.7): 235 B-trim: 0 in 0/61 Lambda= 0.075482 statistics sampled from 33600 (33936) to 33600 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.398), width: 16 Scan time: 11.850 The best scores are: opt bits E(85289) NP_001308286 (OMIM: 606010) nuclear receptor-bindi ( 535) 3502 395.3 2.4e-109 NP_037524 (OMIM: 606010) nuclear receptor-binding ( 535) 3502 395.3 2.4e-109 NP_001308291 (OMIM: 606010) nuclear receptor-bindi ( 534) 3484 393.4 9.4e-109 NP_001308288 (OMIM: 606010) nuclear receptor-bindi ( 543) 3476 392.5 1.7e-108 NP_001308287 (OMIM: 606010) nuclear receptor-bindi ( 543) 3476 392.5 1.7e-108 NP_001308290 (OMIM: 606010) nuclear receptor-bindi ( 542) 3458 390.5 6.7e-108 NP_001308292 (OMIM: 606010) nuclear receptor-bindi ( 503) 2574 294.2 6.1e-79 NP_848659 (OMIM: 615563) nuclear receptor-binding ( 501) 1958 227.1 9.6e-59 XP_016868872 (OMIM: 615563) PREDICTED: nuclear rec ( 557) 1872 217.8 6.7e-56 XP_016868868 (OMIM: 615563) PREDICTED: nuclear rec ( 612) 1872 217.9 7.1e-56 XP_016868871 (OMIM: 615563) PREDICTED: nuclear rec ( 574) 1869 217.5 8.6e-56 XP_016868869 (OMIM: 615563) PREDICTED: nuclear rec ( 606) 1869 217.6 8.8e-56 XP_016868867 (OMIM: 615563) PREDICTED: nuclear rec ( 661) 1869 217.6 9.3e-56 XP_016868870 (OMIM: 615563) PREDICTED: nuclear rec ( 593) 1783 208.2 5.8e-53 XP_016875328 (OMIM: 201300,605232,614492) PREDICTE (2043) 502 69.4 1.2e-10 XP_011519311 (OMIM: 201300,605232,614492) PREDICTE (2107) 502 69.4 1.2e-10 XP_011519310 (OMIM: 201300,605232,614492) PREDICTE (2108) 502 69.4 1.2e-10 NP_055638 (OMIM: 201300,605232,614492) serine/thre (2134) 502 69.5 1.2e-10 XP_016875327 (OMIM: 201300,605232,614492) PREDICTE (2135) 502 69.5 1.2e-10 XP_016875326 (OMIM: 201300,605232,614492) PREDICTE (2136) 502 69.5 1.2e-10 XP_016875325 (OMIM: 201300,605232,614492) PREDICTE (2200) 502 69.5 1.2e-10 XP_016875324 (OMIM: 201300,605232,614492) PREDICTE (2201) 502 69.5 1.2e-10 XP_016875323 (OMIM: 201300,605232,614492) PREDICTE (2228) 502 69.5 1.2e-10 XP_011519309 (OMIM: 201300,605232,614492) PREDICTE (2353) 502 69.5 1.3e-10 XP_011519308 (OMIM: 201300,605232,614492) PREDICTE (2354) 502 69.5 1.3e-10 XP_006719066 (OMIM: 201300,605232,614492) PREDICTE (2381) 502 69.5 1.3e-10 NP_061852 (OMIM: 201300,605232,614492) serine/thre (2382) 502 69.5 1.3e-10 XP_011519306 (OMIM: 201300,605232,614492) PREDICTE (2548) 502 69.6 1.3e-10 XP_011519305 (OMIM: 201300,605232,614492) PREDICTE (2549) 502 69.6 1.3e-10 NP_998820 (OMIM: 201300,605232,614492) serine/thre (2634) 502 69.6 1.4e-10 XP_011519304 (OMIM: 201300,605232,614492) PREDICTE (2641) 502 69.6 1.4e-10 NP_001171914 (OMIM: 201300,605232,614492) serine/t (2642) 502 69.6 1.4e-10 XP_011519303 (OMIM: 201300,605232,614492) PREDICTE (2702) 502 69.6 1.4e-10 XP_011519302 (OMIM: 201300,605232,614492) PREDICTE (2730) 502 69.6 1.4e-10 XP_011519300 (OMIM: 201300,605232,614492) PREDICTE (2794) 502 69.6 1.4e-10 XP_011519301 (OMIM: 201300,605232,614492) PREDICTE (2794) 502 69.6 1.4e-10 XP_011519299 (OMIM: 201300,605232,614492) PREDICTE (2795) 502 69.6 1.4e-10 XP_006724656 (OMIM: 300358) PREDICTED: serine/thre (1743) 493 68.4 2.1e-10 NP_001002838 (OMIM: 300358) serine/threonine-prote (1743) 493 68.4 2.1e-10 XP_011529104 (OMIM: 300358) PREDICTED: serine/thre (1753) 493 68.4 2.1e-10 XP_016885234 (OMIM: 300358) PREDICTED: serine/thre (1790) 493 68.4 2.1e-10 XP_016885233 (OMIM: 300358) PREDICTED: serine/thre (1800) 493 68.4 2.2e-10 NP_065973 (OMIM: 300358) serine/threonine-protein (1800) 493 68.4 2.2e-10 XP_016885232 (OMIM: 300358) PREDICTED: serine/thre (1800) 493 68.4 2.2e-10 XP_016885231 (OMIM: 300358) PREDICTED: serine/thre (1800) 493 68.4 2.2e-10 XP_016885230 (OMIM: 300358) PREDICTED: serine/thre (1800) 493 68.4 2.2e-10 XP_016870544 (OMIM: 606249) PREDICTED: serine/thre (2162) 483 67.4 5.1e-10 XP_016870543 (OMIM: 606249) PREDICTED: serine/thre (2163) 483 67.4 5.1e-10 XP_005252201 (OMIM: 606249) PREDICTED: serine/thre (2185) 483 67.4 5.1e-10 XP_011517238 (OMIM: 606249) PREDICTED: serine/thre (2190) 483 67.4 5.1e-10 >>NP_001308286 (OMIM: 606010) nuclear receptor-binding p (535 aa) initn: 3502 init1: 3502 opt: 3502 Z-score: 2084.1 bits: 395.3 E(85289): 2.4e-109 Smith-Waterman score: 3502; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS 490 500 510 520 530 >>NP_037524 (OMIM: 606010) nuclear receptor-binding prot (535 aa) initn: 3502 init1: 3502 opt: 3502 Z-score: 2084.1 bits: 395.3 E(85289): 2.4e-109 Smith-Waterman score: 3502; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS 490 500 510 520 530 >>NP_001308291 (OMIM: 606010) nuclear receptor-binding p (534 aa) initn: 3482 init1: 1846 opt: 3484 Z-score: 2073.5 bits: 393.4 E(85289): 9.4e-109 Smith-Waterman score: 3484; 99.8% identity (99.8% similar) in 535 aa overlap (1-535:1-534) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFFAPEYG-VTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL 420 430 440 450 460 470 490 500 510 520 530 pF1KB9 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS 480 490 500 510 520 530 >>NP_001308288 (OMIM: 606010) nuclear receptor-binding p (543 aa) initn: 2051 init1: 2051 opt: 3476 Z-score: 2068.7 bits: 392.5 E(85289): 1.7e-108 Smith-Waterman score: 3476; 98.5% identity (98.5% similar) in 543 aa overlap (1-535:1-543) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSV--------APDTINNHVKT ::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 CREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 QLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 QQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 NRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVT 490 500 510 520 530 540 pF1KB9 VSS ::: NP_001 VSS >>NP_001308287 (OMIM: 606010) nuclear receptor-binding p (543 aa) initn: 2051 init1: 2051 opt: 3476 Z-score: 2068.7 bits: 392.5 E(85289): 1.7e-108 Smith-Waterman score: 3476; 98.5% identity (98.5% similar) in 543 aa overlap (1-535:1-543) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSV--------APDTINNHVKT ::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 CREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 QLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 QQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 NRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVT 490 500 510 520 530 540 pF1KB9 VSS ::: NP_001 VSS >>NP_001308290 (OMIM: 606010) nuclear receptor-binding p (542 aa) initn: 2959 init1: 1516 opt: 3458 Z-score: 2058.1 bits: 390.5 E(85289): 6.7e-108 Smith-Waterman score: 3458; 98.3% identity (98.3% similar) in 543 aa overlap (1-535:1-542) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSV--------APDTINNHVKT ::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVFHRIFANVAPDTINNHVKT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 CREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 QLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENA ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLEDPLQR-FIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENA 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 LEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRP 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 QQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKL 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 NRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVT 480 490 500 510 520 530 pF1KB9 VSS ::: NP_001 VSS 540 >>NP_001308292 (OMIM: 606010) nuclear receptor-binding p (503 aa) initn: 2570 init1: 2570 opt: 2574 Z-score: 1538.2 bits: 294.2 E(85289): 6.1e-79 Smith-Waterman score: 3215; 94.0% identity (94.0% similar) in 535 aa overlap (1-535:1-503) 10 20 30 40 50 60 pF1KB9 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDN :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKV------ 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW :::::::::::::::::::::::::::::::::: NP_001 --------------------------IFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRW 120 130 140 190 200 210 220 230 240 pF1KB9 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNL 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQ 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB9 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNM 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB9 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB9 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDL 390 400 410 420 430 440 490 500 510 520 530 pF1KB9 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS 450 460 470 480 490 500 >>NP_848659 (OMIM: 615563) nuclear receptor-binding prot (501 aa) initn: 1852 init1: 948 opt: 1958 Z-score: 1175.7 bits: 227.1 E(85289): 9.6e-59 Smith-Waterman score: 1964; 62.4% identity (80.4% similar) in 489 aa overlap (44-518:17-496) 20 30 40 50 60 70 pF1KB9 SDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQ :.:.::::::.:::::::::::::::.::: NP_848 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQ 10 20 30 40 80 90 100 110 120 130 pF1KB9 RNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFH :.::..:..:::::::::::::::..:..:: . .:::...::..:. ..: ::::.: NP_848 GNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLH 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB9 KYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHS ::: : .: :::::::::.:::::::::::::::::.:: .::::::::::::::.::. NP_848 KYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHA 110 120 130 140 150 160 200 210 220 230 240 pF1KB9 CDPPIIHGNLTCDTIFIQHNGLIKIGSV--------APDTINNHVKTCREEQKNLHFFAP :.::::::::: :::::::::::::::: :: . . ... ::: .::::: : NP_848 CSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 EYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQ :::::.. :::::.::::::::::::::: ::.. : .:::. : . : :: .:::: NP_848 EYGEVAD-GTAVDIFSFGMCALEMAVLEIQTNGDTR-VTEEAIARARHSLSDPNMREFIL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAV :: .:::::.:. :::: .:::: :::::::::.. ::...:::..:: :: :: :: NP_848 CCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAV 290 300 310 320 330 340 370 380 390 400 410 pF1KB9 LAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAF------GLPRPQQPQQEE :::.: : : :.: ::. .:::::::::::::::: : :::: : :: NP_848 LAELPR-PRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEE 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 VTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCD : . .::::::: . :::::. ::::.: :. .. :::::: :::.:.:.:. : NP_848 VQK------AKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYD 410 420 430 440 450 480 490 500 510 520 530 pF1KB9 LMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS :.:... .::.:::. ::. : :. .:...:: :. :. NP_848 LLPTDSAQDLASELVHYGFLHEDDRMKLAAFLESTFLKYRGTQA 460 470 480 490 500 >>XP_016868872 (OMIM: 615563) PREDICTED: nuclear recepto (557 aa) initn: 1762 init1: 948 opt: 1872 Z-score: 1124.6 bits: 217.8 E(85289): 6.7e-56 Smith-Waterman score: 1878; 63.4% identity (80.2% similar) in 464 aa overlap (44-493:17-469) 20 30 40 50 60 70 pF1KB9 SDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQ :.:.::::::.:::::::::::::::.::: XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQ 10 20 30 40 80 90 100 110 120 130 pF1KB9 RNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFH :.::..:..:::::::::::::::..:..:: . .:::...::..:. ..: ::::.: XP_016 GNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLH 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB9 KYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHS ::: : .: :::::::::.:::::::::::::::::.:: .::::::::::::::.::. XP_016 KYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHA 110 120 130 140 150 160 200 210 220 230 240 pF1KB9 CDPPIIHGNLTCDTIFIQHNGLIKIGSV--------APDTINNHVKTCREEQKNLHFFAP :.::::::::: :::::::::::::::: :: . . ... ::: .::::: : XP_016 CSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 EYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQ :::::.. :::::.::::::::::::::: ::.. : .:::. : . : :: .:::: XP_016 EYGEVAD-GTAVDIFSFGMCALEMAVLEIQTNGDTR-VTEEAIARARHSLSDPNMREFIL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAV :: .:::::.:. :::: .:::: :::::::::.. ::...:::..:: :: :: :: XP_016 CCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAV 290 300 310 320 330 340 370 380 390 400 410 pF1KB9 LAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAF------GLPRPQQPQQEE :::.: : : :.: ::. .:::::::::::::::: : :::: : :: XP_016 LAELPR-PRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEE 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 VTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCD : . .::::::: . :::::. ::::.: :. .. :::::: :::.:.:.:. : XP_016 VQK------AKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYD 410 420 430 440 450 480 490 500 510 520 530 pF1KB9 LMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS :.: . :. :..: XP_016 LLPRR--PDEAGRLPGEHLPQVPWDPGLTRSPSPRGPCRGAAWAGHVGETPAPWGCPPPC 460 470 480 490 500 510 >>XP_016868868 (OMIM: 615563) PREDICTED: nuclear recepto (612 aa) initn: 1762 init1: 948 opt: 1872 Z-score: 1124.1 bits: 217.9 E(85289): 7.1e-56 Smith-Waterman score: 1878; 63.4% identity (80.2% similar) in 464 aa overlap (44-493:17-469) 20 30 40 50 60 70 pF1KB9 SDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQ :.:.::::::.:::::::::::::::.::: XP_016 MAAPEPAPRRAREREREREDESEDESDILEESPCGRWQKRREQVNQ 10 20 30 40 80 90 100 110 120 130 pF1KB9 RNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFH :.::..:..:::::::::::::::..:..:: . .:::...::..:. ..: ::::.: XP_016 GNMPGLQSTFLAMDTEEGVEVVWNELHFGDRKAFAAHEEKIQTVFEQLVLVDHPNIVKLH 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB9 KYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHS ::: : .: :::::::::.:::::::::::::::::.:: .::::::::::::::.::. XP_016 KYWLDTSEACARVIFITEYVSSGSLKQFLKKTKKNHKAMNARAWKRWCTQILSALSFLHA 110 120 130 140 150 160 200 210 220 230 240 pF1KB9 CDPPIIHGNLTCDTIFIQHNGLIKIGSV--------APDTINNHVKTCREEQKNLHFFAP :.::::::::: :::::::::::::::: :: . . ... ::: .::::: : XP_016 CSPPIIHGNLTSDTIFIQHNGLIKIGSVWHRIFSNALPDDLRSPIRAEREELRNLHFFPP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 EYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQ :::::.. :::::.::::::::::::::: ::.. : .:::. : . : :: .:::: XP_016 EYGEVAD-GTAVDIFSFGMCALEMAVLEIQTNGDTR-VTEEAIARARHSLSDPNMREFIL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAV :: .:::::.:. :::: .:::: :::::::::.. ::...:::..:: :: :: :: XP_016 CCLARDPARRPSAHSLLFHRVLFEVHSLKLLAAHCFIQHQYLMPENVVEEKTKAMDLHAV 290 300 310 320 330 340 370 380 390 400 410 pF1KB9 LAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAF------GLPRPQQPQQEE :::.: : : :.: ::. .:::::::::::::::: : :::: : :: XP_016 LAELPR-PRRPPLQWRYSEVSFMELDKFLEDVRNGIYPLMNFAATRPLGLPRVLAPPPEE 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 VTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCD : . .::::::: . :::::. ::::.: :. .. :::::: :::.:.:.:. : XP_016 VQK------AKTPTPEPFDSETRKVIQMQCNLERSEDKARWHLTLLLVLEDRLHRQLTYD 410 420 430 440 450 480 490 500 510 520 530 pF1KB9 LMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS :.: . :. :..: XP_016 LLPRR--PDEAGRLPGEHLPQVPWDPGLTRSPSPRGPCRGAAWAGHVGETPAPWGCPPPC 460 470 480 490 500 510 535 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:59:42 2016 done: Sat Nov 5 14:59:44 2016 Total Scan time: 11.850 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]