FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9957, 538 aa 1>>>pF1KB9957 538 - 538 aa - 538 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3287+/-0.000454; mu= 18.5388+/- 0.028 mean_var=74.1642+/-15.054, 0's: 0 Z-trim(109.2): 27 B-trim: 0 in 0/54 Lambda= 0.148928 statistics sampled from 17315 (17335) to 17315 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.203), width: 16 Scan time: 7.050 The best scores are: opt bits E(85289) XP_006711560 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 538) 3541 770.9 0 XP_016857671 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 538) 3541 770.9 0 NP_001166995 (OMIM: 600063) 60 kDa SS-A/Ro ribonuc ( 538) 3541 770.9 0 NP_004591 (OMIM: 600063) 60 kDa SS-A/Ro ribonucleo ( 538) 3541 770.9 0 XP_016857670 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 538) 3541 770.9 0 NP_001035829 (OMIM: 600063) 60 kDa SS-A/Ro ribonuc ( 534) 3479 757.6 2.2e-218 NP_001035828 (OMIM: 600063) 60 kDa SS-A/Ro ribonuc ( 525) 3379 736.1 6.3e-212 NP_001166996 (OMIM: 600063) 60 kDa SS-A/Ro ribonuc ( 518) 3376 735.4 9.7e-212 XP_016857669 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 560) 2241 491.6 2.6e-138 XP_006711558 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 560) 2241 491.6 2.6e-138 XP_006711559 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 560) 2241 491.6 2.6e-138 XP_011508224 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 263) 1731 381.8 1.4e-105 NP_001317949 (OMIM: 600063) 60 kDa SS-A/Ro ribonuc ( 263) 1731 381.8 1.4e-105 XP_016857672 (OMIM: 600063) PREDICTED: 60 kDa SS-A ( 263) 1731 381.8 1.4e-105 >>XP_006711560 (OMIM: 600063) PREDICTED: 60 kDa SS-A/Ro (538 aa) initn: 3541 init1: 3541 opt: 3541 Z-score: 4113.8 bits: 770.9 E(85289): 0 Smith-Waterman score: 3541; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI 490 500 510 520 530 >>XP_016857671 (OMIM: 600063) PREDICTED: 60 kDa SS-A/Ro (538 aa) initn: 3541 init1: 3541 opt: 3541 Z-score: 4113.8 bits: 770.9 E(85289): 0 Smith-Waterman score: 3541; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI 490 500 510 520 530 >>NP_001166995 (OMIM: 600063) 60 kDa SS-A/Ro ribonucleop (538 aa) initn: 3541 init1: 3541 opt: 3541 Z-score: 4113.8 bits: 770.9 E(85289): 0 Smith-Waterman score: 3541; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI 490 500 510 520 530 >>NP_004591 (OMIM: 600063) 60 kDa SS-A/Ro ribonucleoprot (538 aa) initn: 3541 init1: 3541 opt: 3541 Z-score: 4113.8 bits: 770.9 E(85289): 0 Smith-Waterman score: 3541; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI 490 500 510 520 530 >>XP_016857670 (OMIM: 600063) PREDICTED: 60 kDa SS-A/Ro (538 aa) initn: 3541 init1: 3541 opt: 3541 Z-score: 4113.8 bits: 770.9 E(85289): 0 Smith-Waterman score: 3541; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI 490 500 510 520 530 >>NP_001035829 (OMIM: 600063) 60 kDa SS-A/Ro ribonucleop (534 aa) initn: 3479 init1: 3479 opt: 3479 Z-score: 4041.8 bits: 757.6 E(85289): 2.2e-218 Smith-Waterman score: 3479; 100.0% identity (100.0% similar) in 528 aa overlap (1-528:1-528) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDPCKIPY 490 500 510 520 530 >>NP_001035828 (OMIM: 600063) 60 kDa SS-A/Ro ribonucleop (525 aa) initn: 3379 init1: 3379 opt: 3379 Z-score: 3925.8 bits: 736.1 E(85289): 6.3e-212 Smith-Waterman score: 3379; 99.6% identity (100.0% similar) in 516 aa overlap (1-516:1-516) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI ::::::::::::::::::::::::::::::::::.. NP_001 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRALQNTLLNKSF 490 500 510 520 >>NP_001166996 (OMIM: 600063) 60 kDa SS-A/Ro ribonucleop (518 aa) initn: 3376 init1: 3376 opt: 3376 Z-score: 3922.4 bits: 735.4 E(85289): 9.7e-212 Smith-Waterman score: 3376; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPA 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI :::::::::::::::::::::::::::::::::: NP_001 IALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRDTVK 490 500 510 >>XP_016857669 (OMIM: 600063) PREDICTED: 60 kDa SS-A/Ro (560 aa) initn: 3519 init1: 2234 opt: 2241 Z-score: 2604.0 bits: 491.6 E(85289): 2.6e-138 Smith-Waterman score: 3477; 96.1% identity (96.1% similar) in 560 aa overlap (1-538:1-560) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 pF1KB9 DLLRLSHLKPSSE----------G------------LAIVTKYITKGWKEVHELYKEKAL ::::::::::::: : :::::::::::::::::::::::: XP_016 DLLRLSHLKPSSEVKLEKTATQKGGFTFQFCGLKPRLAIVTKYITKGWKEVHELYKEKAL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 SVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 TALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 GKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAA 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 MCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTN 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB9 TPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLD 490 500 510 520 530 540 520 530 pF1KB9 MCGFDTGALDVIRNFTLDMI :::::::::::::::::::: XP_016 MCGFDTGALDVIRNFTLDMI 550 560 >>XP_006711558 (OMIM: 600063) PREDICTED: 60 kDa SS-A/Ro (560 aa) initn: 3519 init1: 2234 opt: 2241 Z-score: 2604.0 bits: 491.6 E(85289): 2.6e-138 Smith-Waterman score: 3477; 96.1% identity (96.1% similar) in 560 aa overlap (1-538:1-560) 10 20 30 40 50 60 pF1KB9 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHK 130 140 150 160 170 180 190 200 210 pF1KB9 DLLRLSHLKPSSE----------G------------LAIVTKYITKGWKEVHELYKEKAL ::::::::::::: : :::::::::::::::::::::::: XP_006 DLLRLSHLKPSSEVKLEKTATQKGGFTFQFCGLKPRLAIVTKYITKGWKEVHELYKEKAL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 SVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 TALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 GKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAA 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 MCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTN 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB9 TPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLD 490 500 510 520 530 540 520 530 pF1KB9 MCGFDTGALDVIRNFTLDMI :::::::::::::::::::: XP_006 MCGFDTGALDVIRNFTLDMI 550 560 538 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:17:47 2016 done: Sat Nov 5 08:17:48 2016 Total Scan time: 7.050 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]