Result of FASTA (omim) for
pF1KB9959
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9959, 538 aa
1>>>pF1KB9959 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9256+/-0.0003; mu= 7.9193+/- 0.019
mean_var=166.6388+/-32.917, 0's: 0 Z-trim(122.1): 140 B-trim: 77 in 1/60
Lambda= 0.099354
statistics sampled from 39485 (39645) to 39485 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.465), width: 16
Scan time: 10.100
The best scores are: opt bits E(85289)
NP_001036189 (OMIM: 600798) nectin-2 isoform delta ( 538) 3592 526.7 7.1e-149
NP_002847 (OMIM: 600798) nectin-2 isoform alpha pr ( 479) 2373 351.9 2.6e-96
XP_011525494 (OMIM: 600798) PREDICTED: nectin-2 is ( 369) 2324 344.8 2.7e-94
NP_001129242 (OMIM: 173850) poliovirus receptor is ( 392) 1006 155.9 2.1e-37
NP_006496 (OMIM: 173850) poliovirus receptor isofo ( 417) 1006 155.9 2.2e-37
NP_001129240 (OMIM: 173850) poliovirus receptor is ( 372) 998 154.7 4.5e-37
NP_001129241 (OMIM: 173850) poliovirus receptor is ( 364) 993 154.0 7.2e-37
NP_976030 (OMIM: 225060,600644) nectin-1 isoform 2 ( 458) 609 99.0 3.2e-20
XP_016861615 (OMIM: 607147) PREDICTED: nectin-3 is ( 510) 579 94.8 6.9e-19
NP_001230217 (OMIM: 607147) nectin-3 isoform 3 [Ho ( 487) 578 94.6 7.3e-19
XP_016861612 (OMIM: 607147) PREDICTED: nectin-3 is ( 541) 578 94.7 8e-19
NP_002846 (OMIM: 225060,600644) nectin-1 isoform 1 ( 517) 569 93.3 1.9e-18
NP_976031 (OMIM: 225060,600644) nectin-1 isoform 3 ( 352) 530 87.6 6.7e-17
NP_056295 (OMIM: 607147) nectin-3 isoform 1 precur ( 549) 483 81.0 1e-14
XP_016861614 (OMIM: 607147) PREDICTED: nectin-3 is ( 526) 482 80.9 1.1e-14
XP_016861613 (OMIM: 607147) PREDICTED: nectin-3 is ( 534) 482 80.9 1.1e-14
XP_011510965 (OMIM: 607147) PREDICTED: nectin-3 is ( 580) 482 80.9 1.2e-14
NP_001230215 (OMIM: 607147) nectin-3 isoform 2 pre ( 366) 468 78.8 3.3e-14
NP_112178 (OMIM: 609607,613573) nectin-4 precursor ( 510) 401 69.3 3.3e-11
XP_011508323 (OMIM: 609607,613573) PREDICTED: nect ( 511) 397 68.7 4.9e-11
XP_011508325 (OMIM: 609607,613573) PREDICTED: nect ( 460) 395 68.4 5.5e-11
XP_005245565 (OMIM: 609607,613573) PREDICTED: nect ( 485) 394 68.2 6.4e-11
XP_011508324 (OMIM: 609607,613573) PREDICTED: nect ( 486) 390 67.7 9.5e-11
XP_006713145 (OMIM: 609938) PREDICTED: cell adhesi ( 395) 346 61.3 6.4e-09
XP_016861552 (OMIM: 609938) PREDICTED: cell adhesi ( 397) 346 61.3 6.4e-09
NP_001161147 (OMIM: 609938) cell adhesion molecule ( 404) 346 61.3 6.5e-09
XP_016861616 (OMIM: 607147) PREDICTED: nectin-3 is ( 337) 337 60.0 1.4e-08
NP_001161146 (OMIM: 609938) cell adhesion molecule ( 435) 329 58.9 3.7e-08
XP_006713144 (OMIM: 609938) PREDICTED: cell adhesi ( 435) 329 58.9 3.7e-08
NP_694854 (OMIM: 609938) cell adhesion molecule 2 ( 437) 329 58.9 3.7e-08
XP_016861551 (OMIM: 609938) PREDICTED: cell adhesi ( 449) 329 58.9 3.8e-08
NP_001091987 (OMIM: 605686) cell adhesion molecule ( 414) 316 57.0 1.3e-07
XP_016872947 (OMIM: 605686) PREDICTED: cell adhesi ( 402) 305 55.4 3.8e-07
NP_055148 (OMIM: 605686) cell adhesion molecule 1 ( 442) 305 55.5 4.1e-07
NP_001287973 (OMIM: 605686) cell adhesion molecule ( 453) 305 55.5 4.2e-07
NP_001287972 (OMIM: 605686) cell adhesion molecule ( 471) 305 55.5 4.3e-07
XP_016872946 (OMIM: 605686) PREDICTED: cell adhesi ( 477) 305 55.5 4.3e-07
NP_001120645 (OMIM: 609743) cell adhesion molecule ( 398) 302 55.0 5.1e-07
NP_067012 (OMIM: 609743) cell adhesion molecule 3 ( 432) 302 55.0 5.4e-07
XP_005271551 (OMIM: 605686) PREDICTED: cell adhesi ( 425) 301 54.9 5.9e-07
NP_001287974 (OMIM: 605686) cell adhesion molecule ( 443) 301 54.9 6.1e-07
NP_001243434 (OMIM: 609938) cell adhesion molecule ( 287) 284 52.3 2.3e-06
NP_001243433 (OMIM: 609938) cell adhesion molecule ( 287) 284 52.3 2.3e-06
NP_001243432 (OMIM: 609938) cell adhesion molecule ( 327) 267 49.9 1.4e-05
NP_001243431 (OMIM: 609938) cell adhesion molecule ( 327) 267 49.9 1.4e-05
XP_016872950 (OMIM: 605686) PREDICTED: cell adhesi ( 267) 253 47.9 4.8e-05
XP_016872949 (OMIM: 605686) PREDICTED: cell adhesi ( 295) 242 46.3 0.00016
XP_016872948 (OMIM: 605686) PREDICTED: cell adhesi ( 324) 242 46.3 0.00017
XP_011524624 (OMIM: 114890) PREDICTED: carcinoembr ( 524) 242 46.5 0.00024
XP_016881635 (OMIM: 114890) PREDICTED: carcinoembr ( 617) 242 46.5 0.00028
>>NP_001036189 (OMIM: 600798) nectin-2 isoform delta pre (538 aa)
initn: 3592 init1: 3592 opt: 3592 Z-score: 2793.8 bits: 526.7 E(85289): 7.1e-149
Smith-Waterman score: 3592; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV
490 500 510 520 530
>>NP_002847 (OMIM: 600798) nectin-2 isoform alpha precur (479 aa)
initn: 2408 init1: 2340 opt: 2373 Z-score: 1850.2 bits: 351.9 E(85289): 2.6e-96
Smith-Waterman score: 2373; 90.4% identity (95.5% similar) in 397 aa overlap (1-394:1-397)
10 20 30 40 50 60
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTA--GAGA-
:::::::::::::::::::::::::::::::::::::::::::::::::: .. .:
NP_002 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 TGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEA
. : .:: . ... : .. .... : .:.... ::
NP_002 VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 QEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSP
NP_002 VFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV
430 440 450 460 470
>>XP_011525494 (OMIM: 600798) PREDICTED: nectin-2 isofor (369 aa)
initn: 2319 init1: 2319 opt: 2324 Z-score: 1813.9 bits: 344.8 E(85289): 2.7e-94
Smith-Waterman score: 2324; 96.4% identity (97.5% similar) in 362 aa overlap (1-362:1-362)
10 20 30 40 50 60
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
::::::::::::::::::::::::::::::::::::::::::::::: . . :.
XP_011 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRALEDDMESQLDGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
.:
XP_011 LISRRAVYV
>>NP_001129242 (OMIM: 173850) poliovirus receptor isofor (392 aa)
initn: 1128 init1: 964 opt: 1006 Z-score: 792.5 bits: 155.9 E(85289): 2.1e-37
Smith-Waterman score: 1133; 50.0% identity (72.8% similar) in 368 aa overlap (19-379:9-363)
10 20 30 40 50
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
:::::. :: :. :: ::. .: : :: .: :::.
NP_001 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
: .: . ..: .:: : .. .:.:: .:::. :.:: ::.:. .
NP_001 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
NP_001 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
NP_001 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :.: : .
NP_001 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 AGAT-GGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKA
.: . ..:: ... .. . . ::
NP_001 SGMSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSEHHQSCRN
340 350 360 370 380 390
>>NP_006496 (OMIM: 173850) poliovirus receptor isoform a (417 aa)
initn: 1128 init1: 964 opt: 1006 Z-score: 792.1 bits: 155.9 E(85289): 2.2e-37
Smith-Waterman score: 1133; 50.0% identity (72.8% similar) in 368 aa overlap (19-379:9-363)
10 20 30 40 50
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
:::::. :: :. :: ::. .: : :: .: :::.
NP_006 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
: .: . ..: .:: : .. .:.:: .:::. :.:: ::.:. .
NP_006 LQVPNMEVTHVSQLTWARHGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG---
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
NP_006 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
NP_006 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_006 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :.: : .
NP_006 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 AGAT-GGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKA
.: . ..:: ... .. . . ::
NP_006 SGMSRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVS
340 350 360 370 380 390
>>NP_001129240 (OMIM: 173850) poliovirus receptor isofor (372 aa)
initn: 1126 init1: 962 opt: 998 Z-score: 786.6 bits: 154.7 E(85289): 4.5e-37
Smith-Waterman score: 1125; 52.3% identity (74.1% similar) in 344 aa overlap (19-356:9-339)
10 20 30 40 50
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
:::::. :: :. :: ::. .: : :: .: :::.
NP_001 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
: .: . ..: .:: : .. ..:.:: .:::. :.:: ::.:. .
NP_001 LQVPNMEVTHVSQLTWAR---HGESGSMAVFHQTQGPSYSE----SKRLEFVAARLG---
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
NP_001 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
NP_001 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :.: : .
NP_001 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEH
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 AGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAK
.:
NP_001 SGTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
340 350 360 370
>>NP_001129241 (OMIM: 173850) poliovirus receptor isofor (364 aa)
initn: 1110 init1: 946 opt: 993 Z-score: 782.9 bits: 154.0 E(85289): 7.2e-37
Smith-Waterman score: 1120; 52.1% identity (74.5% similar) in 349 aa overlap (19-361:9-343)
10 20 30 40 50
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCH
:::::. :: :. :: ::. .: : :: .: :::.
NP_001 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCY
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 L-LPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQ
: .: . ..: .:: : .. ..:.:: .:::. :.:: ::.:. .
NP_001 LQVPNMEVTHVSQLTWAR---HGESGSMAVFHQTQGPSYSE----SKRLEFVAARLG---
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 DTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFS
:::..:.: . :: ::::::::: :.:::.:: ::::.:::.: ::.::: ..
NP_001 ---AELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLT
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV
.:. .: :.: :::::.:.: :.: . .:: : :.::::::: . ::::...::
NP_001 GEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGK
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGY
.:::::::::::.: :. :.:.: :::::::::::.:::::...:::.::.:::::::::
NP_001 NVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 DWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG
.:::: : .: :::::.::.:. ::. .:::..:.::::.: .:: .. :. : . :.
NP_001 NWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKGTEH-AS
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 AGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAK
:.:.: .
NP_001 ASANGHVSYSAVSRENSSSQDPQTEGTR
340 350 360
>>NP_976030 (OMIM: 225060,600644) nectin-1 isoform 2 pre (458 aa)
initn: 676 init1: 213 opt: 609 Z-score: 484.0 bits: 99.0 E(85289): 3.2e-20
Smith-Waterman score: 753; 33.6% identity (59.6% similar) in 470 aa overlap (19-463:14-454)
10 20 30 40 50
pF1KB9 MARAAALLPSRSPPTPLLWPLLLLL--LLETGAQDVRVQVLPEVRGQLGGTVELPCHLLP
: : : : .. :... ::: . : .: : : : .
NP_976 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFAN
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEA
:.:.. :. ::::. .. ...:::: ..:.:: : .: ::. :. .
NP_976 PLPSVKITQVTWQK-STNGSKQNVAIYNPSMGVSVLAPY--RERVEFLRPS---------
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 ELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF-----
. :.:. : : .:::: : ::::::: :. ... : :.::: : :. ....
NP_976 -FTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG
..: . :: : : .:.::. .:: . : ::. .. . ::::: ::. :::: .:
NP_976 QDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNP-NGTVTVISRYRLVPSREAHQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 VTVTCKVEH--ESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEP
...: :.. . :.: .::.:.: :::.: :.: :::: : :. :.: . .::
NP_976 QSLACIVNYHMDRFKES----LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPA
230 240 250 260 270
300 310 320 330 340
pF1KB9 TGYDWSTTSGTFPTSAVAQGSQLVIHA-VDSLFNTTFVCTVTNAVGMGRAEQV-IFVRET
: : :.: .:..: .. ::. : ... .. . :..: .:: .: :. :: . . :
NP_976 TEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGT-RSGQVEVNITEK
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB9 PNTA-GAGATGGIIGGIIAA-IIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYK
: : :... ...: .:. .: .:: .. .: :::.. .:: :. : : :
NP_976 PRPQRGLGSAARLLAGTVAVFLILVAVLTVFFLYNRQQKSPPETDGAGTDQ----PLSQK
340 350 360 370 380 390
410 420 430 440 450
pF1KB9 P-PTP--KAKLEAQEMPSQLFTLGASEHSP--------LKTPYFDAGASCTEQEMPRYHE
: :.: ...: ... . : .... :. ::.: :.: : ::
NP_976 PEPSPSRQSSLVPEDIQVVHLDPGRQQQQEEEDLQKLSLQPPYYDLGVS------PSYHP
400 410 420 430 440
460 470 480 490 500 510
pF1KB9 -LPTLEERSGPLHPGATSLGSPIPVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDA
. : : :
NP_976 SVRTTEPRGECP
450
>>XP_016861615 (OMIM: 607147) PREDICTED: nectin-3 isofor (510 aa)
initn: 490 init1: 325 opt: 579 Z-score: 460.1 bits: 94.8 E(85289): 6.9e-19
Smith-Waterman score: 662; 30.2% identity (60.4% similar) in 437 aa overlap (13-439:33-440)
10 20 30
pF1KB9 MARAAALLPSRSPPTP-----LLWPLLLLLLLETGAQDVRVQ
:::: ::.::::. : :: .
XP_016 RTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRL-CGALAGPII
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 VLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPK
: :.: . : .: : : : : . :. ..:.. . .. :.::. ::..: : .
XP_016 VEPHVTAVWGKNVSLKC--LIEV-NETITQISWEKIHGKSS-QTVAVHHPQYGFSVQGEY
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 PGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR
: :. : . :.:::..::.. : :.: :. .::: :.... : .
XP_016 QG--RVLF----------KNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVT
120 130 140 150 160
160 170 180 190 200 210
pF1KB9 VIAKPKNQ--AEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAG
:...: . ... . . :..:.::. :.: :.:.: ..: :. ...
XP_016 VLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLG--EMESTTTSFPNE
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB9 TVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLG
:.:. :.. : :. : : .:: :.: ..:. :...: ::::..::: ::..:
XP_016 TATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVG
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB9 RTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQL-VIHAVDSLFNTTFVCTVTNA
: ..:.:.. .:: : :: .: .: . .:. . : .: . .. ...: :::.
XP_016 RKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNS
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB9 VGMGRAEQVIFVRETP--NTAGAGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQ
.:. ..::.. ..: .:.. ...:..::...: .: :. .: .: :..:
XP_016 LGQRSDQKVIYISDVPFKQTSSIAVAGAVIGAVLALFII-AIFVTVLLTPRKKRPSYL--
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB9 GAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMP
:. .. ::..::: : . .. .:.. : :: ::.: .
XP_016 ----DKVIDLPPTHKPP-PLYEERSPPLPQK--DLFQPEHLPLQTQFKEREVGNLQHSNG
410 420 430 440 450
460 470 480 490 500 510
pF1KB9 RYHELPTLEERSGPLHPGATSLGSPIPVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPI
XP_016 LNSRSFDYEDENPVGEDGIQQMYPLYNQMCYQDRSPGKHHQNNDPKRVYIDPREHYV
460 470 480 490 500 510
>>NP_001230217 (OMIM: 607147) nectin-3 isoform 3 [Homo s (487 aa)
initn: 397 init1: 325 opt: 578 Z-score: 459.6 bits: 94.6 E(85289): 7.3e-19
Smith-Waterman score: 622; 29.3% identity (61.4% similar) in 409 aa overlap (36-439:37-417)
10 20 30 40 50 60
pF1KB9 ALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYI
. : :.: . : .: : : : : . :
NP_001 WCFVRRTPGLLRGPLLPRSFSGNPRALAGPIIVEPHVTAVWGKNVSLKC--LIEV-NETI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATL
. ..:.. . .. :.::. ::..: : . : :. : :. . :.:::.
NP_001 TQISWEKIHGKSS-QTVAVHHPQYGFSVQGEYQG--RVLF---KNYS-------LNDATI
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQ--AEAQKVTFSQDPTTVALC
.::.. : :.: :. .::: :.... : . :...: . ... . . :..:.:
NP_001 TLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAIC
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 ISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHE
:. :.: :.:.: ..: :. ... :.:. :.. : :. : : .:: :.:
NP_001 IAATGKPVAHIDWEGDLG--EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHP
180 190 200 210 220
250 260 270 280 290 300
pF1KB9 SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTF
..:. :...: ::::..::: ::..:: ..:.:.. .:: : :: .: .
NP_001 ALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQW
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 PTSAVAQGSQL-VIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP--NTAGAGATGG
: . .:. . : .: . .. ...: :::..:. ..::.. ..: .:.. ...:.
NP_001 PDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDVPFKQTSSIAVAGA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
.::...: .: :. .: .: :..: :. .. ::..::: : . .. .
NP_001 VIGAVLALFII-AIFVTVLLTPRKKRPSYL------DKVIDLPPTHKPP-PLYEERSPPL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB9 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
:.. : :: ::.: .
NP_001 PQK--DLFQPEHLPLQTQFKEREVGNLQHSNGLNSRSFDYEDENPVGEDGIQQMYPLYNQ
410 420 430 440 450
538 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:19:47 2016 done: Fri Nov 4 09:19:49 2016
Total Scan time: 10.100 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]