Result of FASTA (omim) for
pF1KB9967
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9967, 551 aa
1>>>pF1KB9967 551 - 551 aa - 551 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3563+/-0.00055; mu= 18.9759+/- 0.033
mean_var=82.8067+/-18.313, 0's: 0 Z-trim(108.1): 230 B-trim: 714 in 1/50
Lambda= 0.140942
statistics sampled from 15905 (16177) to 15905 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.53), E-opt: 0.2 (0.19), width: 16
Scan time: 9.430
The best scores are: opt bits E(85289)
NP_003050 (OMIM: 180300,604190) solute carrier fam ( 551) 3640 750.9 2.4e-216
NP_003051 (OMIM: 212140,603377) solute carrier fam ( 557) 2873 594.9 2.2e-169
XP_016865265 (OMIM: 180300,604190) PREDICTED: solu ( 375) 2438 506.3 6.8e-143
XP_006714738 (OMIM: 180300,604190) PREDICTED: solu ( 375) 2438 506.3 6.8e-143
NP_001295051 (OMIM: 212140,603377) solute carrier ( 581) 2035 424.5 4.4e-118
XP_011541891 (OMIM: 180300,604190) PREDICTED: solu ( 459) 1776 371.8 2.6e-102
XP_016865267 (OMIM: 212140,603377) PREDICTED: solu ( 381) 1747 365.8 1.4e-100
XP_011541892 (OMIM: 212140,603377) PREDICTED: solu ( 351) 1536 322.9 1.1e-87
NP_003049 (OMIM: 602608) solute carrier family 22 ( 555) 967 207.3 1e-52
XP_011534506 (OMIM: 608276) PREDICTED: solute carr ( 534) 939 201.6 5e-51
NP_149116 (OMIM: 608276) solute carrier family 22 ( 577) 939 201.7 5.3e-51
NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 918 197.4 1e-49
NP_006663 (OMIM: 604995) solute carrier family 22 ( 546) 881 189.8 1.8e-47
XP_006715034 (OMIM: 604995) PREDICTED: solute carr ( 549) 864 186.4 2e-46
NP_696961 (OMIM: 604995) solute carrier family 22 ( 548) 855 184.6 7.1e-46
XP_005267160 (OMIM: 602607) PREDICTED: solute carr ( 573) 855 184.6 7.4e-46
NP_060890 (OMIM: 608275) solute carrier family 22 ( 547) 854 184.4 8.2e-46
XP_011534507 (OMIM: 608276) PREDICTED: solute carr ( 515) 849 183.3 1.6e-45
XP_005267159 (OMIM: 602607) PREDICTED: solute carr ( 610) 845 182.6 3.2e-45
NP_004247 (OMIM: 604047) solute carrier family 22 ( 551) 834 180.3 1.4e-44
XP_016874051 (OMIM: 607582) PREDICTED: solute carr ( 551) 807 174.8 6.2e-43
NP_695008 (OMIM: 607582) solute carrier family 22 ( 550) 798 173.0 2.2e-42
NP_653186 (OMIM: 220150,607096) solute carrier fam ( 553) 787 170.7 1e-41
NP_004781 (OMIM: 607582) solute carrier family 22 ( 563) 784 170.1 1.6e-41
NP_004245 (OMIM: 607581) solute carrier family 22 ( 542) 782 169.7 2.1e-41
NP_001171661 (OMIM: 607581) solute carrier family ( 542) 782 169.7 2.1e-41
NP_001171662 (OMIM: 607581) solute carrier family ( 451) 779 169.0 2.8e-41
XP_006715615 (OMIM: 602607) PREDICTED: solute carr ( 483) 778 168.9 3.3e-41
NP_694857 (OMIM: 602607) solute carrier family 22 ( 506) 776 168.5 4.6e-41
NP_068812 (OMIM: 604842) solute carrier family 22 ( 556) 767 166.7 1.8e-40
NP_060954 (OMIM: 607097) solute carrier family 22 ( 550) 744 162.0 4.4e-39
XP_006715033 (OMIM: 604995) PREDICTED: solute carr ( 551) 738 160.8 1e-38
XP_011534508 (OMIM: 608276) PREDICTED: solute carr ( 483) 721 157.3 1e-37
XP_005267241 (OMIM: 608276) PREDICTED: solute carr ( 407) 717 156.4 1.6e-37
XP_011534511 (OMIM: 608276) PREDICTED: solute carr ( 442) 717 156.4 1.7e-37
XP_011534510 (OMIM: 608276) PREDICTED: solute carr ( 447) 717 156.4 1.7e-37
XP_011534509 (OMIM: 608276) PREDICTED: solute carr ( 459) 717 156.4 1.7e-37
XP_005267163 (OMIM: 604842) PREDICTED: solute carr ( 425) 708 154.6 5.8e-37
XP_016865687 (OMIM: 604995) PREDICTED: solute carr ( 602) 705 154.1 1.2e-36
XP_011512559 (OMIM: 604995) PREDICTED: solute carr ( 607) 704 153.9 1.3e-36
XP_016865689 (OMIM: 604995) PREDICTED: solute carr ( 543) 699 152.8 2.5e-36
XP_011512558 (OMIM: 604995) PREDICTED: solute carr ( 610) 699 152.9 2.7e-36
XP_016865690 (OMIM: 604995) PREDICTED: solute carr ( 420) 691 151.1 6.4e-36
XP_011512563 (OMIM: 604995) PREDICTED: solute carr ( 420) 691 151.1 6.4e-36
XP_011534513 (OMIM: 608276) PREDICTED: solute carr ( 417) 682 149.3 2.3e-35
XP_011543666 (OMIM: 607581) PREDICTED: solute carr ( 419) 682 149.3 2.3e-35
NP_001171665 (OMIM: 607581) solute carrier family ( 419) 682 149.3 2.3e-35
XP_011534378 (OMIM: 604842) PREDICTED: solute carr ( 404) 671 147.0 1e-34
XP_011534377 (OMIM: 604842) PREDICTED: solute carr ( 404) 671 147.0 1e-34
XP_016866692 (OMIM: 604842) PREDICTED: solute carr ( 404) 671 147.0 1e-34
>>NP_003050 (OMIM: 180300,604190) solute carrier family (551 aa)
initn: 3640 init1: 3640 opt: 3640 Z-score: 4005.0 bits: 750.9 E(85289): 2.4e-216
Smith-Waterman score: 3640; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551)
10 20 30 40 50 60
pF1KB9 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 DYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMET
490 500 510 520 530 540
550
pF1KB9 EENPKVLITAF
:::::::::::
NP_003 EENPKVLITAF
550
>>NP_003051 (OMIM: 212140,603377) solute carrier family (557 aa)
initn: 2854 init1: 1897 opt: 2873 Z-score: 3162.1 bits: 594.9 E(85289): 2.2e-169
Smith-Waterman score: 2873; 76.5% identity (90.8% similar) in 557 aa overlap (1-551:1-557)
10 20 30 40 50 60
pF1KB9 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
::::::: ::::::::::::::::::::::::::.:.: ::: .::::::::::::::::
NP_003 MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
::::..::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_003 AWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQ
:::::::.::::::::::.::.::: ::::::::::::.:::::::::::::::.::..:
NP_003 QDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFA
:::::::::: ..:::.::::.::::::::::.::.:::::::::::::::::::: :.:
NP_003 TGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA
:::.:::::::::::::::.:::.:::::: ::::::::::::::: ::.::: ::.::
NP_003 FGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKA
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 AKMNNIAVPAVIFDSVE--ELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFA
:: :.:.::..::: : .:. :::. ::::.:: :: ..::::..::: :::::.
NP_003 AKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 LSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLV
::::.:::::: ..::::::..:.:::. :::::. ::::: .:..:: ::.::::.:::
NP_003 LSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 PVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYF
: : :.:. :::.::::.:.::::.::.:::::::.::::.:::.:::::.:::..:::
NP_003 PPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 VYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGK---KTR
::::::.:.::::.:::::.: .:::::.:::.: ::.:..:: .:: .. : .::
NP_003 VYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTR
490 500 510 520 530 540
540 550
pF1KB9 DSMETEENPKVLI-TAF
. .: : .: :::
NP_003 MLKDGQERPTILKSTAF
550
>>XP_016865265 (OMIM: 180300,604190) PREDICTED: solute c (375 aa)
initn: 2438 init1: 2438 opt: 2438 Z-score: 2686.4 bits: 506.3 E(85289): 6.8e-143
Smith-Waterman score: 2438; 100.0% identity (100.0% similar) in 375 aa overlap (177-551:1-375)
150 160 170 180 190 200
pF1KB9 SLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMG
::::::::::::::::::::::::::::::
XP_016 MAVQTGFSFLQIFSISWEMFTVLFVIVGMG
10 20 30
210 220 230 240 250 260
pF1KB9 QISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB9 GVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQK
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB9 AFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYI
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB9 TAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYV
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB9 FTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF
280 290 300 310 320 330
510 520 530 540 550
pF1KB9 FPESLGMTLPETLEQMQKVKWFRSGKKTRDSMETEENPKVLITAF
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPESLGMTLPETLEQMQKVKWFRSGKKTRDSMETEENPKVLITAF
340 350 360 370
>>XP_006714738 (OMIM: 180300,604190) PREDICTED: solute c (375 aa)
initn: 2438 init1: 2438 opt: 2438 Z-score: 2686.4 bits: 506.3 E(85289): 6.8e-143
Smith-Waterman score: 2438; 100.0% identity (100.0% similar) in 375 aa overlap (177-551:1-375)
150 160 170 180 190 200
pF1KB9 SLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMG
::::::::::::::::::::::::::::::
XP_006 MAVQTGFSFLQIFSISWEMFTVLFVIVGMG
10 20 30
210 220 230 240 250 260
pF1KB9 QISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB9 GVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQK
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB9 AFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYI
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB9 TAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYV
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB9 FTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF
280 290 300 310 320 330
510 520 530 540 550
pF1KB9 FPESLGMTLPETLEQMQKVKWFRSGKKTRDSMETEENPKVLITAF
:::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPESLGMTLPETLEQMQKVKWFRSGKKTRDSMETEENPKVLITAF
340 350 360 370
>>NP_001295051 (OMIM: 212140,603377) solute carrier fami (581 aa)
initn: 2014 init1: 1057 opt: 2035 Z-score: 2241.0 bits: 424.5 E(85289): 4.4e-118
Smith-Waterman score: 2815; 73.3% identity (87.1% similar) in 581 aa overlap (1-551:1-581)
10 20 30 40 50 60
pF1KB9 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
::::::: ::::::::::::::::::::::::::.:.: ::: .::::::::::::::::
NP_001 MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
::::..::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 AWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
70 80 90 100 110 120
130 140 150
pF1KB9 QDVYLSTVVTE------------------------WNLVCEDNWKVPLTTSLFFVGVLLG
:::::::.::: :::::::.::.::: ::::::::::
NP_001 QDVYLSTIVTEQDSGAYNAMKNRMGKKPALCLPAQWNLVCEDDWKAPLTISLFFVGVLLG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 SFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFI
::.:::::::::::::::.::..::::::::::: ..:::.::::.::::::::::.::.
NP_001 SFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 LGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWF
:::::::::::::::::::: :.: :::.:::::::::::::::.:::.:::::: ::::
NP_001 LGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWF
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 IPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVE--ELNPLKQQKAFILDLFR
::::::::::: ::.::: ::.:::: :.:.::..::: : .:. :::. ::::.:
NP_001 IPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLR
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB9 TRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRT
: :: ..::::..::: :::::.::::.:::::: ..::::::..:.:::. :::::.
NP_001 TWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB9 LPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPT
::::: .:..:: ::.::::.:::: : :.:. :::.::::.:.::::.::.:::::::
NP_001 LPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 LVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMT
.::::.:::.:::::.:::..:::::::::.:.::::.:::::.: .:::::.:::.:
NP_001 VVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTP
490 500 510 520 530 540
520 530 540 550
pF1KB9 LPETLEQMQKVKWFRSGK---KTRDSMETEENPKVLI-TAF
::.:..:: .:: .. : .:: . .: : .: :::
NP_001 LPDTIDQMLRVKGMKHRKTPSHTRMLKDGQERPTILKSTAF
550 560 570 580
>>XP_011541891 (OMIM: 180300,604190) PREDICTED: solute c (459 aa)
initn: 2658 init1: 1776 opt: 1776 Z-score: 1957.7 bits: 371.8 E(85289): 2.6e-102
Smith-Waterman score: 2485; 76.8% identity (79.1% similar) in 551 aa overlap (1-551:1-459)
10 20 30 40 50 60
pF1KB9 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQ
::::::::::: :. .: :.. : .:
XP_011 QDVYLSTVVTEV-------WQ----------------------EERSLRNHG--CTDWLQ
130 140
190 200 210 220 230 240
pF1KB9 TGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFA
.::. .. : :: :. : . : .:
XP_011 LPADFLH------QLGDVHCVICHRGH----------GPD------------LQLC----
150 160 170
250 260 270 280 290 300
pF1KB9 VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA
: : . :::::::::::::::::::::::::
XP_011 --------------------------GSLHTR---FIPESPRWLISQRRFREAEDIIQKA
180 190 200
310 320 330 340 350 360
pF1KB9 AKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALS
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB9 LDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPV
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB9 DYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVY
330 340 350 360 370 380
490 500 510 520 530 540
pF1KB9 LGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMET
390 400 410 420 430 440
550
pF1KB9 EENPKVLITAF
:::::::::::
XP_011 EENPKVLITAF
450
>>XP_016865267 (OMIM: 212140,603377) PREDICTED: solute c (381 aa)
initn: 1728 init1: 971 opt: 1747 Z-score: 1926.9 bits: 365.8 E(85289): 1.4e-100
Smith-Waterman score: 1747; 69.6% identity (87.9% similar) in 381 aa overlap (177-551:1-381)
150 160 170 180 190 200
pF1KB9 SLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMG
:..::::::::::: ..:::.::::.::::
XP_016 MGMQTGFSFLQIFSKNFEMFVVLFVLVGMG
10 20 30
210 220 230 240 250 260
pF1KB9 QISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVP
::::::.::.:::::::::::::::::::: :.: :::.:::::::::::::::.:::.:
XP_016 QISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB9 GVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVE--ELNPLKQ
::::: ::::::::::::::: ::.::: ::.:::: :.:.::..::: : .:. ::
XP_016 GVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQ
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB9 QKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPA
:. ::::.:: :: ..::::..::: :::::.::::.:::::: ..::::::..:.::
XP_016 QSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPA
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB9 YITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSML
:. :::::. ::::: .:..:: ::.::::.:::: : :.:. :::.::::.:.::::.
XP_016 YVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMV
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB9 YVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILT
::.:::::::.::::.:::.:::::.:::..:::::::::.:.::::.:::::.: .:::
XP_016 YVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT
280 290 300 310 320 330
510 520 530 540 550
pF1KB9 LFFPESLGMTLPETLEQMQKVKWFRSGK---KTRDSMETEENPKVLI-TAF
::.:::.: ::.:..:: .:: .. : .:: . .: : .: :::
XP_016 LFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTRMLKDGQERPTILKSTAF
340 350 360 370 380
>>XP_011541892 (OMIM: 212140,603377) PREDICTED: solute c (351 aa)
initn: 1517 init1: 971 opt: 1536 Z-score: 1695.6 bits: 322.9 E(85289): 1.1e-87
Smith-Waterman score: 1536; 68.5% identity (86.8% similar) in 340 aa overlap (218-551:12-351)
190 200 210 220 230 240
pF1KB9 IFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLP
::::::::::::::::::: :.: :::.::
XP_011 MWQHLSWVWPSGTEILGKSVRIIFSTLGVCIFYAFGYMVLP
10 20 30 40
250 260 270 280 290 300
pF1KB9 LFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIA
:::::::::::::.:::.:::::: ::::::::::::::: ::.::: ::.:::: :.:.
XP_011 LFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIV
50 60 70 80 90 100
310 320 330 340 350 360
pF1KB9 VPAVIFDSVE--ELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPN
::..::: : .:. :::. ::::.:: :: ..::::..::: :::::.::::.::
XP_011 VPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPN
110 120 130 140 150 160
370 380 390 400 410 420
pF1KB9 LHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYYFL
:::: ..::::::..:.:::. :::::. ::::: .:..:: ::.::::.:::: : :.:
XP_011 LHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYL
170 180 190 200 210 220
430 440 450 460 470 480
pF1KB9 SIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYN
. :::.::::.:.::::.::.:::::::.::::.:::.:::::.:::..:::::::::.
XP_011 ATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYD
230 240 250 260 270 280
490 500 510 520 530 540
pF1KB9 RMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGK---KTRDSMETEE
:.::::.:::::.: .:::::.:::.: ::.:..:: .:: .. : .:: . .:
XP_011 RFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTRMLKDGQE
290 300 310 320 330 340
550
pF1KB9 NPKVLI-TAF
: .: :::
XP_011 RPTILKSTAF
350
>>NP_003049 (OMIM: 602608) solute carrier family 22 memb (555 aa)
initn: 896 init1: 489 opt: 967 Z-score: 1067.6 bits: 207.3 E(85289): 1e-52
Smith-Waterman score: 967; 34.9% identity (64.2% similar) in 545 aa overlap (5-533:6-540)
10 20 30 40 50
pF1KB9 MRDYDEVIAFLGEWGPFQRLIFFLL---SASIIPNGFNGMSVVFLAGTPEHRCRVPDAA
:.:. ::. ::. .:::: ::.. : . : .:::. ::.:::: : .:
NP_003 MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPI-YVG--IVFLGFTPDHRCRSPGVA
10 20 30 40 50
60 70 80 90 100
pF1KB9 NLS--SAWR-----NNSVPLRLRDGREVPHSCSRYRLA-TIANFSALGLEPGRDVDLGQL
.:: .: : .:: :. :..: ::.. . ..:. . . :.. ..:
NP_003 ELSLRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 EQESCLDGWEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFG
: ::: . .. :..:::.:::: ..: . : : :: ..::. : ..::::
NP_003 PLGPCRDGWVY--ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 RKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRI
:: :..:. .... . :. .: .. . .. .: :. . .......:: ::..:. :
NP_003 RKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYR-
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB9 IFSTLGVC--TFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLIS
:.:. . ..:: ..: :: . :: : .....:. . . .: ::::::::::
NP_003 --RTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLIS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB9 QRRFREAEDIIQKAAKMNNIAVPAVIFD-SVEELNPLKQQKAFILDLFRTRNIAIMTIMS
: . :: ::.. :: :. ..:: . .:: . : . .: ::: :: .: :..
NP_003 QNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSF-LDLVRTPQIRKHTMIL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB9 LLLWMLTSVGYFALSLDAPNLHGDA-YLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAV
. :. .:: : .: . .: :: ::. : :::.:.:: . : . . ::: ::
NP_003 MYNWFTSSVLYQGLIMHM-GLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAAS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB9 LFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVT
. .:.. : ..: : .:.: . ::..::: :. .. . .::::::..::..: .
NP_003 NMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHIC
420 430 440 450 460 470
470 480 490 500 510 520
pF1KB9 STASRVGSIIAPYFVY-LGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQ
:. .:.::.:..:: : :: .:.: : .. : :.:..::. : .::::.:. .
NP_003 SSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAE
480 490 500 510 520 530
530 540 550
pF1KB9 KVKWFRSGKKTRDSMETEENPKVLITAF
... :..:.
NP_003 NMQRPRKNKEKMIYLQVQKLDIPLN
540 550
>>XP_011534506 (OMIM: 608276) PREDICTED: solute carrier (534 aa)
initn: 969 init1: 470 opt: 939 Z-score: 1037.0 bits: 201.6 E(85289): 5e-51
Smith-Waterman score: 944; 33.3% identity (64.3% similar) in 526 aa overlap (45-543:4-517)
20 30 40 50
pF1KB9 GPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVP-----------------DAAN
::.: :: : :..
XP_011 MGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGA
10 20 30
60 70 80 90 100 110
pF1KB9 LSSAWRNNSVPLRLRDGREVPHS-CSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDG
: :. ... : ..:..:. : ::: . : :.:: : :. .. :.::
XP_011 LLSSGQKDYVTVQLQNGEIWELSRCSRNKRE---NTSSLGYEY-----TGSKKEFPCVDG
40 50 60 70 80
120 130 140 150 160 170
pF1KB9 WEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFAT
. ..:... ::.::.:::::. .: . : ::. :::::: . : .:::.::. ::.::
XP_011 YIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWAT
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 MAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVC
. . :.. :.... : . ...: . ::.:. :..: . : .... .
XP_011 SSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRT-WASVHLH
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB9 TFFAVGYMLLPLFAYFIRDW---RMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREA
.::::: .:. : .:..: : .:.: ..::: .:: : .::.: ::.:. :..::
XP_011 SFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCC---WVLPETPFWLLSEGRYEEA
210 220 230 240 250 260
300 310 320 330 340
pF1KB9 EDIIQKAAKMNNIA------VPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLL
. :.. :: : . . .. ... .: . :: . :: . .:. :. :
XP_011 QKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWL
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB9 LWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFW
.:. :.:....::.. :: :. ::: :: ...::::: . . . . :: ..: ::
XP_011 IWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFC
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB9 GGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTA
.. . ....: .:.:.. .:.:::.: .::...:..:::::::.::..::: : .
XP_011 SALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMV
390 400 410 420 430 440
470 480 490 500 510 520
pF1KB9 SRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKW
:..::.::. : :.. ..: . .:....: :.::: .::.:: : : :. :..
XP_011 CRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLES
450 460 470 480 490 500
530 540 550
pF1KB9 FRSGKKTRDSMETEENPKVLITAF
.:... . :...
XP_011 ENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE
510 520 530
551 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:59:36 2016 done: Sat Nov 5 07:59:38 2016
Total Scan time: 9.430 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]