FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9970, 703 aa 1>>>pF1KB9970 703 - 703 aa - 703 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4157+/-0.00122; mu= 15.7730+/- 0.073 mean_var=180.8841+/-35.528, 0's: 0 Z-trim(108.0): 206 B-trim: 48 in 2/50 Lambda= 0.095362 statistics sampled from 9679 (9913) to 9679 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.305), width: 16 Scan time: 3.890 The best scores are: opt bits E(32554) CCDS14067.1 FBLN1 gene_id:2192|Hs108|chr22 ( 703) 5092 714.1 1.8e-205 CCDS14068.1 FBLN1 gene_id:2192|Hs108|chr22 ( 601) 4173 587.5 1.9e-167 CCDS43028.1 FBLN1 gene_id:2192|Hs108|chr22 ( 566) 4166 586.5 3.5e-167 CCDS14069.1 FBLN1 gene_id:2192|Hs108|chr22 ( 683) 4166 586.6 4e-167 CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3 (1184) 1858 269.4 2.1e-71 CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3 (1231) 1729 251.7 4.8e-66 CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5 (2912) 738 115.8 9e-25 CCDS30956.1 HMCN1 gene_id:83872|Hs108|chr1 (5635) 692 109.9 1.1e-22 CCDS9831.1 LTBP2 gene_id:4053|Hs108|chr14 (1821) 682 107.9 1.4e-22 CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557) 658 104.5 1.3e-21 CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19 (1587) 658 104.5 1.3e-21 CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19 (1624) 658 104.5 1.3e-21 CCDS55265.1 MATN2 gene_id:4147|Hs108|chr8 ( 937) 637 101.3 6.8e-21 CCDS55264.1 MATN2 gene_id:4147|Hs108|chr8 ( 956) 637 101.3 6.9e-21 CCDS83309.1 MATN2 gene_id:4147|Hs108|chr8 ( 915) 623 99.4 2.6e-20 CCDS41237.1 MEGF6 gene_id:1953|Hs108|chr1 (1541) 566 91.8 8.1e-18 CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2 (1353) 557 90.5 1.8e-17 CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11 ( 443) 545 88.2 2.8e-17 CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256) 549 89.4 3.6e-17 CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303) 549 89.4 3.7e-17 CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2 ( 493) 523 85.3 2.4e-16 CCDS12196.1 FBN3 gene_id:84467|Hs108|chr19 (2809) 522 86.1 7.8e-16 CCDS4800.1 SCUBE3 gene_id:222663|Hs108|chr6 ( 993) 515 84.6 8e-16 CCDS53599.1 SCUBE2 gene_id:57758|Hs108|chr11 ( 807) 508 83.5 1.4e-15 CCDS7797.2 SCUBE2 gene_id:57758|Hs108|chr11 ( 971) 508 83.6 1.5e-15 CCDS81553.1 SCUBE2 gene_id:57758|Hs108|chr11 ( 999) 508 83.6 1.6e-15 CCDS13149.1 CD93 gene_id:22918|Hs108|chr20 ( 652) 504 82.8 1.8e-15 CCDS54787.1 NPNT gene_id:255743|Hs108|chr4 ( 536) 498 81.9 2.8e-15 CCDS34046.1 NPNT gene_id:255743|Hs108|chr4 ( 565) 498 81.9 2.9e-15 CCDS58645.1 ADGRE1 gene_id:2015|Hs108|chr19 ( 867) 493 81.5 6e-15 CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2 (1342) 494 81.8 7.1e-15 CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2 (1395) 494 81.9 7.3e-15 CCDS14048.1 SCUBE1 gene_id:80274|Hs108|chr22 ( 988) 491 81.2 7.9e-15 CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2 (1721) 494 82.0 8.3e-15 CCDS58644.1 ADGRE1 gene_id:2015|Hs108|chr19 ( 821) 483 80.0 1.5e-14 CCDS12175.1 ADGRE1 gene_id:2015|Hs108|chr19 ( 886) 483 80.1 1.6e-14 CCDS54784.1 NPNT gene_id:255743|Hs108|chr4 ( 582) 478 79.2 2e-14 CCDS54786.1 NPNT gene_id:255743|Hs108|chr4 ( 566) 446 74.7 4.1e-13 CCDS54785.1 NPNT gene_id:255743|Hs108|chr4 ( 595) 446 74.8 4.2e-13 CCDS2923.1 PROS1 gene_id:5627|Hs108|chr3 ( 676) 446 74.8 4.6e-13 CCDS44864.1 NELL2 gene_id:4753|Hs108|chr12 ( 815) 447 75.1 4.6e-13 CCDS8746.1 NELL2 gene_id:4753|Hs108|chr12 ( 816) 447 75.1 4.7e-13 CCDS53781.1 NELL2 gene_id:4753|Hs108|chr12 ( 839) 447 75.1 4.7e-13 CCDS44863.1 NELL2 gene_id:4753|Hs108|chr12 ( 866) 447 75.1 4.8e-13 CCDS8002.1 VWCE gene_id:220001|Hs108|chr11 ( 955) 436 73.7 1.5e-12 CCDS32232.1 FBN1 gene_id:2200|Hs108|chr15 (2871) 443 75.2 1.5e-12 CCDS7113.1 CUBN gene_id:8029|Hs108|chr10 (3623) 436 74.4 3.3e-12 CCDS43905.1 NOTCH1 gene_id:4851|Hs108|chr9 (2555) 425 72.7 7.6e-12 CCDS908.1 NOTCH2 gene_id:4853|Hs108|chr1 (2471) 423 72.4 9e-12 CCDS12326.1 NOTCH3 gene_id:4854|Hs108|chr19 (2321) 420 72.0 1.2e-11 >>CCDS14067.1 FBLN1 gene_id:2192|Hs108|chr22 (703 aa) initn: 5092 init1: 5092 opt: 5092 Z-score: 3802.3 bits: 714.1 E(32554): 1.8e-205 Smith-Waterman score: 5092; 99.9% identity (100.0% similar) in 703 aa overlap (1-703:1-703) 10 20 30 40 50 60 pF1KB9 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS14 AQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVV 610 620 630 640 650 660 670 680 690 700 pF1KB9 RQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF ::::::::::::::::::::::::::::::::::::::::::: CCDS14 RQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF 670 680 690 700 >>CCDS14068.1 FBLN1 gene_id:2192|Hs108|chr22 (601 aa) initn: 4535 init1: 4173 opt: 4173 Z-score: 3119.8 bits: 587.5 E(32554): 1.9e-167 Smith-Waterman score: 4173; 99.1% identity (99.8% similar) in 571 aa overlap (1-571:1-571) 10 20 30 40 50 60 pF1KB9 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS14 AQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTV :::::::::::::::::::::::::: ...: CCDS14 TCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSKEDCRVLPWKQGLEDTHLD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 ISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVV CCDS14 A >>CCDS43028.1 FBLN1 gene_id:2192|Hs108|chr22 (566 aa) initn: 4166 init1: 4166 opt: 4166 Z-score: 3114.9 bits: 586.5 E(32554): 3.5e-167 Smith-Waterman score: 4166; 99.8% identity (100.0% similar) in 566 aa overlap (1-566:1-566) 10 20 30 40 50 60 pF1KB9 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS43 AQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTV :::::::::::::::::::::::::: CCDS43 TCFNIQGGFRCLAFECPENYRRSAAT 550 560 >>CCDS14069.1 FBLN1 gene_id:2192|Hs108|chr22 (683 aa) initn: 4166 init1: 4166 opt: 4166 Z-score: 3114.0 bits: 586.6 E(32554): 4e-167 Smith-Waterman score: 4224; 85.6% identity (90.3% similar) in 700 aa overlap (1-699:1-680) 10 20 30 40 50 60 pF1KB9 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 CRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS14 AQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 TCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIK-SCRPNDVTCVFDPVHTISHT :::::::::::::::::::::::::: :: . :. : : :.. :.. CCDS14 TCFNIQGGFRCLAFECPENYRRSAAT---------RCERLPCHENR-ECSKLPLR-ITYY 550 560 570 580 600 610 620 630 640 650 pF1KB9 VISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGV .:.:: .. : ..: . : . .. . :: :: . : : .. . :: CCDS14 HLSFPT--NIQAPA-VVF--RMGPSSAVPGDSMQLAITGGNEEGFFTT--RKVSPHS-GV 590 600 610 620 630 640 660 670 680 690 700 pF1KB9 VRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF : ..:. : .: ..:. :.:: :... :::: CCDS14 VALTKPVPEPRDLLLTVKMDLSRHGTVSSF-VAKLFIFVSAEL 650 660 670 680 >>CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3 (1184 aa) initn: 2130 init1: 1039 opt: 1858 Z-score: 1395.3 bits: 269.4 E(32554): 2.1e-71 Smith-Waterman score: 1996; 41.4% identity (61.4% similar) in 736 aa overlap (61-701:472-1182) 40 50 60 70 80 90 pF1KB9 VLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDR :: .:..:: : :.: : .:. :.: . CCDS46 IETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGET 450 460 470 480 490 500 100 110 120 130 140 pF1KB9 CATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACC------ :.. :: : .. :.:: :: :: ..:.::::: . .:: :..:. .:: CCDS46 CGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPL 510 520 530 540 550 150 pF1KB9 -----------------VKSQETG--------------------DLD------------- :. : . : : CCDS46 IVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHL 560 570 580 590 600 610 160 170 pF1KB9 ----VGG----------LQETDKIIEVE------EEQEDPYLN----------------- ::. ::. . . : : ..: :. CCDS46 CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQ 620 630 640 650 660 670 180 190 200 210 220 230 pF1KB9 -DRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT . :. .::::: : .: ..:::: :: ...:::::::.:::.: :.: :: :.:: CCDS46 PNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNT 680 690 700 710 720 730 240 250 260 270 280 290 pF1KB9 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS .:::.: . .: :: : .:. :.:.::: : :.: : :.:::: ::: :. . .: . CCDS46 LGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 740 750 760 770 780 790 300 310 320 330 340 350 pF1KB9 GFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVD ::.:: :::.::::: :.: :: : .:::: ::::::.: :.:::: ...::.::: CCDS46 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD 800 810 820 830 840 850 360 370 380 390 400 410 pF1KB9 VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCE :.:: .. ::.:. : : :::.::.::.:. :...: :.::::: ::::: : :: CCDS46 VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 860 870 880 890 900 910 420 430 440 450 460 470 pF1KB9 NTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDG :::::: :::. :: :..::. :::.::: .. :::::::.:::::::::.::::.. :: CCDS46 NTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DG 920 930 940 950 960 970 480 490 500 510 520 530 pF1KB9 VTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNC :: :::::: .: .:..::.:.:::.::.:: .:: .. :::.:.:.:::. : ::: CCDS46 HTCTDIDECA-QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNC 980 990 1000 1010 1020 1030 540 550 560 570 580 590 pF1KB9 SINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTI : ::: ::::.:::: :::: :: .: :: .: .. . . : .:.. : CCDS46 SEAETCHNIQGSFRCLRFECPPNY------VQVSKT---KCERTTCHDFLECQNSPAR-I 1040 1050 1060 1070 1080 600 610 620 630 640 650 pF1KB9 SHTVISLPTFREFTRPEEIIFLRAITPPHPASQANII-FDITEGNLRDSFDIIKRYMDGM .: ... : . : .:. . : :: .. : ..: .:: . : : .... CCDS46 THYQLNFQT--GLLVPAHIFRI----GPAPAFTGDTIALNIIKGNEEGYFG--TRRLNAY 1090 1100 1110 1120 1130 660 670 680 690 700 pF1KB9 TVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF : ::: : .. : .: .::. : :. ....::: . . CCDS46 T-GVVYLQRAVLEPRDFALDVEMKLWRQGSVT-TFLAKMHIFFTTFAL 1140 1150 1160 1170 1180 >>CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3 (1231 aa) initn: 2090 init1: 1039 opt: 1729 Z-score: 1299.2 bits: 251.7 E(32554): 4.8e-66 Smith-Waterman score: 1826; 39.5% identity (59.3% similar) in 740 aa overlap (36-701:521-1229) 10 20 30 40 50 60 pF1KB9 PSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDC-SLPYATESKECRMV ::. : :. .. ..: : : . . : : CCDS46 AGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP--NLGYPCNHV 500 510 520 530 540 70 80 90 100 110 pF1KB9 QEQCCHSQL-----------EELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCC . .::... : .: :. : : : .: : .. : CCDS46 MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDEC 550 560 570 580 590 600 120 130 140 150 pF1KB9 LLGRAAQAQGQSCEYSLM--VG-YQC-----------GQVFRACCVKSQETGDLDVGGLQ :: :. :.. . :: :.: :.. : : . . . . CCDS46 LL-----LPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 610 620 630 640 650 660 160 170 180 190 200 210 pF1KB9 ETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCED--- : ... : : :. .::::: : .: ..:::: :: ...::::::: CCDS46 EFSQVASNTIPLPLPQPNT-CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDE 670 680 690 700 710 720 220 230 pF1KB9 --------------------------------------------VNECITGSHSCRLGES .:::.: :.: :: CCDS46 CLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEH 730 740 750 760 770 780 240 250 260 270 280 290 pF1KB9 CINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL :.::.:::.: . .: :: : .:. :.:.::: : :.: : :.:::: ::: :. . CCDS46 CVNTLGSFHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 790 800 810 820 830 840 300 310 320 330 340 350 pF1KB9 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT .: .::.:: :::.::::: :.: :: : .:::: ::::::.: :.:::: ...:: CCDS46 RCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT 850 860 870 880 890 900 360 370 380 390 400 410 pF1KB9 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG .::::.:: .. ::.:. : : :::.::.::.:. :...: :.::::: ::::: CCDS46 KCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQ 910 920 930 940 950 960 420 430 440 450 460 470 pF1KB9 HKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLS : :::::::: :::. :: :..::. :::.::: .. :::::::.:::::::::.::::. CCDS46 HTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLA 970 980 990 1000 1010 1020 480 490 500 510 520 530 pF1KB9 DVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTG . :: :: :::::: .: .:..::.:.:::.::.:: .:: .. :::.:.:.:::. : CCDS46 E-DGHTCTDIDECA-QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALG 1030 1040 1050 1060 1070 540 550 560 570 580 590 pF1KB9 IHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDP :::: ::: ::::.:::: :::: :: .: :: .: .. . . : .: CCDS46 THNCSEAETCHNIQGSFRCLRFECPPNY------VQVSKT---KCERTTCHDFLECQNSP 1080 1090 1100 1110 1120 1130 600 610 620 630 640 650 pF1KB9 VHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANII-FDITEGNLRDSFDIIKRY .. :.: ... : . : .:. . : :: .. : ..: .:: . : : CCDS46 AR-ITHYQLNFQT--GLLVPAHIFRI----GPAPAFTGDTIALNIIKGNEEGYFG--TRR 1140 1150 1160 1170 1180 660 670 680 690 700 pF1KB9 MDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF ....: ::: : .. : .: .::. : :. ....::: . . CCDS46 LNAYT-GVVYLQRAVLEPRDFALDVEMKLWRQGSVT-TFLAKMHIFFTTFAL 1190 1200 1210 1220 1230 >>CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5 (2912 aa) initn: 342 init1: 272 opt: 738 Z-score: 558.2 bits: 115.8 E(32554): 9e-25 Smith-Waterman score: 957; 30.0% identity (55.4% similar) in 594 aa overlap (36-599:980-1526) 10 20 30 40 50 60 pF1KB9 PSRRVPLPLLLLGGLALLAAGVDADVLLEAC-CADGHRMATHQKDCSLPYATESKECRMV : : .: . . : : :. . CCDS34 GVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC-LDIRMEQCYLKWD 950 960 970 980 990 1000 70 80 90 100 110 pF1KB9 QEQCCHS-----QLEELHCATGISLANEQDRCATPHG-DNASLE---ATFVKRCCHCCLL ...: : ... ::.: . ..: ..: : . .: : :..: : CCDS34 EDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANR--GDVLT 1010 1020 1030 1040 1050 1060 120 130 140 150 160 170 pF1KB9 GRAAQAQGQSCE-YSLMVGY-QCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQED :: . . :. . : : .: ... . . . ::. : . ...: . . CCDS34 GRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDM----EERNCTDIDECRIS 1070 1080 1090 1100 1110 1120 180 190 200 210 220 230 pF1KB9 PYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGES : : : :.: : .: : :: ::. . .: :..:: . :: : . CCDS34 P---DLC-GSGI----CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR-GGT 1130 1140 1150 1160 1170 240 250 260 270 280 290 pF1KB9 CINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK :.:: :::.:. : :.::. . ..: ::.:: . . : . : : .:...: CCDS34 CVNTEGSFQCD----CPLGHELSPSREDCVDINECSLSDNLCR-NGKCVNMIGTYQC--- 1180 1190 1200 1210 1220 300 310 320 330 340 pF1KB9 LQCKSGF--IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE .:. :. : : : ::.::. ... : : :.:::: : .:..:: : CCDS34 -SCNPGYQATPDRQG-CTDIDECMIMNGGCDT--QCTNSEGSYEC-----SCSEGYALMP 1230 1240 1250 1260 1270 350 360 370 380 390 400 pF1KB9 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR .: :.:.::: . : : .:.: :: .:: : :.. . . :.:::::. . CCDS34 DGRSCADIDECENNPDICD-GGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECD-LNSN 1280 1290 1300 1310 1320 1330 410 420 430 440 450 460 pF1KB9 LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSSPCSQE--CANVYGSYQCY .: .:::: ::..: :..:. .. .: :..:: .. :... : :. ::..: CCDS34 ICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS 1340 1350 1360 1370 1380 1390 470 480 490 500 510 520 pF1KB9 CRRGYQLSDVDGVTCEDIDECALPTGGHICSY--RCINIPGSFQCSCPSSGYRLAPNGRN ::.:. .:. : :.:::. .: : :: .:.: :::..:.: : :. . .: . CCDS34 CREGWIG---NGIKCIDLDECS--NGTHQCSINAQCVNTPGSYRCAC-SEGF--TGDGFT 1400 1410 1420 1430 1440 530 540 550 560 570 pF1KB9 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFEC-----PENYRRSAATLQQEKTDTVRC :.:.:::. .:. : : :.:. :..:: :: : . :: ... . ... CCDS34 CSDVDECAENINLCE-NGQCLNVPGAYRC---ECEMGFTPASDSRSCQDIDECSFQNICV 1450 1460 1470 1480 1490 1500 580 590 600 610 620 630 pF1KB9 IKSCR--PNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFD . .: :. :. : . ...: CCDS34 FGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDF 1510 1520 1530 1540 1550 1560 >-- initn: 523 init1: 258 opt: 595 Z-score: 451.9 bits: 96.2 E(32554): 7.5e-19 Smith-Waterman score: 780; 34.7% identity (54.7% similar) in 450 aa overlap (155-567:485-888) 130 140 150 160 170 180 pF1KB9 SCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGG . :: .. :.. ... . :: :: CCDS34 GTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCI--- 460 470 480 490 500 510 190 200 210 220 230 240 pF1KB9 PCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR : .. : : : .::. ..: .: ::.:: :. : :. :.:: ::. :. CCDS34 PTVSSYR-------CECNMGYKQDANG-DCIDVDECT--SNPCTNGD-CVNTPGSYYCK- 520 530 540 550 250 260 270 280 290 300 pF1KB9 DSSCGTGYELTEDN-SCKDIDEC-ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA : .:.. : . .: ::::: ..:. : . : :: :::.: :..:: . CCDS34 ---CHAGFQRTPTKQACIDIDECIQNGVL-C-KNGRCVNTDGSFQC----ICNAGFELTT 560 570 580 590 600 610 310 320 330 340 350 360 pF1KB9 LG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECA : ::.: .:: . . : : ::: .::. : : :. : .: :.::::: CCDS34 DGKNCVDHDECTTTNM-CLNGM-CINEDGSFKCI-----CKPGFVLAPNGRYCTDVDECQ 620 630 640 650 660 370 380 390 400 pF1KB9 PPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNE------------CQR-YPG :. : .:: :.:: :::::.: : .:.:::.. : : .:: CCDS34 TPG-ICMNGH-CINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPG 670 680 690 700 710 720 410 420 430 440 pF1KB9 RLCGHKCENTLGSYL----CS-------------CSVGFRLSVDGRSCEDINECSSSP-- . .: . .: :. :: : ..:::: :::::. .: CCDS34 AVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALDPDI 730 740 750 760 770 450 460 470 480 490 500 pF1KB9 CSQE-CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYR-CINIPGSFQC :.. : :. :::.: : ::. :..: .: ::::: . .:. : : :::..: CCDS34 CANGICENLRGSYRCNCNSGYE-PDASGRNCIDIDECLVNR--LLCDNGLCRNTPGSYSC 780 790 800 810 820 830 510 520 530 540 550 560 pF1KB9 SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATL .:: :: . . ..:.::.:: . : .: .: : :.: : :: . . :.. : CCDS34 TCPP-GYVFRTETETCEDINECES---NPCVNGACRNNLGSFNC---ECSPGSKLSSTGL 840 850 860 870 880 570 580 590 600 610 620 pF1KB9 QQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPA CCDS34 ICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARI 890 900 910 920 930 940 >>CCDS30956.1 HMCN1 gene_id:83872|Hs108|chr1 (5635 aa) initn: 761 init1: 310 opt: 692 Z-score: 520.9 bits: 109.9 E(32554): 1.1e-22 Smith-Waterman score: 1016; 35.9% identity (59.2% similar) in 446 aa overlap (178-586:5109-5525) 150 160 170 180 190 200 pF1KB9 QETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQL :.: .:.::...:... ::: : . CCDS30 IHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTI 5080 5090 5100 5110 5120 5130 210 220 230 240 250 260 pF1KB9 LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDIDEC .:: .:.:..:: : :.:. :..: ::.::.:: ::.:.. : :. ::.::.:: CCDS30 AADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCV--VRCGSGFRRTSDGLSCQDINEC 5140 5150 5160 5170 5180 5190 270 280 290 300 310 320 pF1KB9 ESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI . . : : :..:::.: :. :. : .:.:.::: . : . : CCDS30 QES-SPCHQR--CFNAIGSFHC----GCEPGY-QLKGRKCMDVNECR--QNVCRPDQHCK 5200 5210 5220 5230 5240 330 340 350 360 370 380 pF1KB9 NTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT ::.:.: : . : :. :.:: :.:.::: .. : .. : :. ::.:: : CCDS30 NTRGGYKC---IDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPR 5250 5260 5270 5280 5290 5300 390 400 410 420 430 440 pF1KB9 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN--- :: .:..: :.:.:::.. : . :.:.: :: ::. : : : .: ::.:: .. CCDS30 GYRSQGVGRPCMDINECEQVP-KPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLP 5310 5320 5330 5340 5350 5360 450 460 470 pF1KB9 ----ECSS------SPCS---------QECANVYGSYQCY---------CRRGYQLSDVD . :: :: .. ...:.::. : :: . . . CCDS30 NYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPE 5370 5380 5390 5400 5410 5420 480 490 500 510 520 530 pF1KB9 GV-----TCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECV : :: ::::: . :...: : ::.:: :: ::.:. ::..:::::::. CCDS30 GSEASHDTCVDIDECE---NTDACQHECKNTFGSYQCICPP-GYQLTHNGKTCQDIDECL 5430 5440 5450 5460 5470 540 550 560 570 580 590 pF1KB9 TGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVF .:. :. :::..:...:. :: ::.:. . . :.:.: :::. CCDS30 EQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPV--------SGFCLKNCPPNDLECAL 5480 5490 5500 5510 5520 600 610 620 630 640 650 pF1KB9 DPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKR CCDS30 SPYALEYKLVSLPFGIATNQDLIRLVAYTQDGVMHPRTTFLMVDEEQTVPFALRDENLKG 5530 5540 5550 5560 5570 5580 >>CCDS9831.1 LTBP2 gene_id:4053|Hs108|chr14 (1821 aa) initn: 342 init1: 223 opt: 682 Z-score: 518.8 bits: 107.9 E(32554): 1.4e-22 Smith-Waterman score: 938; 35.0% identity (57.0% similar) in 505 aa overlap (78-563:872-1337) 50 60 70 80 90 100 pF1KB9 KDCSLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVK :. : .: : :. :: :. CCDS98 TPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCT---DDNECLRDPCKG 850 860 870 880 890 110 120 130 140 150 pF1KB9 --RCCH------C-CLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGL :: . : : : . ..: . : . . .: : . : .: :. :. CCDS98 KGRCINRVGSYSCFCYPGYTLATSGATQECQDI--NECEQ--PGVCSGGQCTNTE--GSY 900 910 920 930 940 950 160 170 180 190 200 210 pF1KB9 Q-ETDKIIEVEEEQEDPYLNDRCRGGGPCKQ-QCRDTGDEVVC-SCFVGYQLLSDGVSCE . : :. . .. . .:. :: : : . .: .. .: .: ::. : :: CCDS98 HCECDQGYIMVRKGHCQDINE-CRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSG--SCV 960 970 980 990 1000 220 230 240 250 260 270 pF1KB9 DVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCL :::::.: . : :. : : ::::: :: :::.: :.. :.:.::: : .: CCDS98 DVNECLTPG-VCAHGK-CTNLEGSFRC----SCEQGYEVTSDEKGCQDVDECASRA-SC- 1010 1020 1030 1040 1050 1060 280 290 300 310 320 330 pF1KB9 PDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYT : .: :: ::: : :..:. . :. : :..:: .. . :: : .: :: ::.. CCDS98 PTGLCLNTEGSFACS---ACENGYWVNEDGTACEDLDEC-AFPGVCPSG-VCTNTAGSFS 1070 1080 1090 1100 1110 340 350 360 370 380 390 pF1KB9 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI :. .: ::. . : : ::::: : : : .: :. ::..: : :. . . CCDS98 CK----DCDGGYRPSPLGDSCEDVDECEDPQSSC-LGGECKNTVGSYQCLCPQGFQLAN- 1120 1130 1140 1150 1160 1170 400 410 420 430 440 450 pF1KB9 SRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSS-PC-S . .: :::::. .: :. ::..: :. :: . : ::.:..::... :: . CCDS98 GTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVG 1180 1190 1200 1210 1220 1230 460 470 480 490 500 pF1KB9 QECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQC--S .:.:. ::..: :. :.: : .: : ::::: : .: ...: : :::..: . CCDS98 GHCVNTEGSFNCLCETGFQPSPESG-ECVDIDECE-DYGDPVCGTWKCENSPGSYRCVLG 1240 1250 1260 1270 1280 510 520 530 540 550 560 pF1KB9 CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQ : . :...:::: .: :::::.. :. . : : .:.:::: : .... : CCDS98 C-QPGFHMAPNG-DCIDIDECANDTM-CGSHGFCDNTDGSFRCL---CDQGFEISPSGWD 1290 1300 1310 1320 1330 1340 570 580 590 600 610 620 pF1KB9 QEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPAS CCDS98 CVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTG 1350 1360 1370 1380 1390 1400 >>CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557 aa) initn: 1053 init1: 368 opt: 658 Z-score: 501.7 bits: 104.5 E(32554): 1.3e-21 Smith-Waterman score: 924; 33.9% identity (53.5% similar) in 557 aa overlap (36-560:503-1013) 10 20 30 40 50 60 pF1KB9 PSRRVPLPLLLLGGLALLAAGVDADVLLEAC-CADGHRMATHQKDCSLPYATESKECRMV : : .: :.. . : . ::: : CCDS74 PESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-----IDVDECRRV 480 490 500 510 520 70 80 90 100 110 pF1KB9 QEQC----CHSQLEELHCATGISL-----ANEQ---DRC--ATPHGDNASLEATFVKRCC : :... ..:. : .. : : :.: . : : . : : . : CCDS74 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLC 530 540 550 560 570 580 120 130 140 150 160 pF1KB9 HCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDV---GGLQETDKIIEV : : : .: ::. . : :. : .. :.. .:.. . .: CCDS74 -VCPAGYQAAPHGASCQDVDECTQSPGLCGRGAC--KNLPGSFRCVCPAGFRGSACEEDV 590 600 610 620 630 640 170 180 190 200 210 220 pF1KB9 EEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC .: ..: : :: . : .:. :.: .:.. . :. :.::.:: . : CCDS74 DECAQEP---PPC---GPGR--CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 650 660 670 680 690 230 240 250 260 270 280 pF1KB9 RLGESCINTVGSFRCQRDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSF :. : :: :::.: : :.. : . :.:.::::. : : : :. ::: CCDS74 TYGR-CENTEGSFQC----VCPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGSF 700 710 720 730 740 290 300 310 320 330 340 pF1KB9 RCRPKLQCKSGFIQDALGNCIDINECLSISAPC-PIGHTCINTEGSYTCQKNVPNCGRGY .:: : :: . : : :..:: : . :: : :: : :::::. : .:. :: CCDS74 QCR---TCPSGH-HLHRGRCTDVDECSSGAPPCGPHGH-CTNTEGSFRC-----SCAPGY 750 760 770 780 790 350 360 370 380 390 400 pF1KB9 HL--NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNEC . .. : :.::.:: .. : .:.:. ::: : : :: . :.::.:: CCDS74 RAPSGRPGP-CADVNECLE-GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC 800 810 820 830 840 850 410 420 430 440 450 pF1KB9 QRYPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSS-SP--C-SQECANVY .. :: : :: ::. : : : : . : :: :..:: .: : ::.: : CCDS74 SEED--LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 860 870 880 890 900 910 460 470 480 490 500 510 pF1KB9 GSYQCY--CRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCS--CPSSG :::.: : ::. . .: ::.:.::: : .:: . :: : :::..:. : . : CCDS74 GSYRCVRDCDPGYHAGP-EG-TCDDVDECQ-EYGPEICGAQRCENTPGSYRCTPAC-DPG 920 930 940 950 960 970 520 530 540 550 560 570 pF1KB9 YRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTD :. .:.: .:::.::: . :. . .: :. :.:.:: : ..: CCDS74 YQPTPGG-GCQDVDEC-RNRSFCGAHAVCQNLPGSFQCL---CDQGYEGARDGRHCVDVN 980 990 1000 1010 1020 580 590 600 610 620 630 pF1KB9 TVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANII CCDS74 ECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASP 1030 1040 1050 1060 1070 1080 703 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:06:15 2016 done: Fri Nov 4 09:06:15 2016 Total Scan time: 3.890 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]