Result of FASTA (omim) for
pF1KB9971
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9971, 554 aa
1>>>pF1KB9971 554 - 554 aa - 554 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0279+/-0.000435; mu= 20.4470+/- 0.027
mean_var=78.8517+/-16.256, 0's: 0 Z-trim(111.8): 257 B-trim: 0 in 0/50
Lambda= 0.144434
statistics sampled from 20286 (20565) to 20286 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.241), width: 16
Scan time: 9.570
The best scores are: opt bits E(85289)
NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 3725 786.4 0
XP_005267160 (OMIM: 602607) PREDICTED: solute carr ( 573) 3388 716.2 6.8e-206
XP_005267159 (OMIM: 602607) PREDICTED: solute carr ( 610) 3388 716.2 7.1e-206
NP_694857 (OMIM: 602607) solute carrier family 22 ( 506) 3136 663.7 4e-190
XP_006715615 (OMIM: 602607) PREDICTED: solute carr ( 483) 3135 663.4 4.4e-190
NP_003049 (OMIM: 602608) solute carrier family 22 ( 555) 2714 575.8 1.3e-163
XP_005267162 (OMIM: 602607) PREDICTED: solute carr ( 418) 2046 436.5 8.1e-122
XP_005267161 (OMIM: 602607) PREDICTED: solute carr ( 418) 2046 436.5 8.1e-122
XP_011534376 (OMIM: 602607) PREDICTED: solute carr ( 418) 2046 436.5 8.1e-122
NP_068812 (OMIM: 604842) solute carrier family 22 ( 556) 1884 402.8 1.4e-111
XP_005267163 (OMIM: 604842) PREDICTED: solute carr ( 425) 1452 312.7 1.5e-84
XP_016866692 (OMIM: 604842) PREDICTED: solute carr ( 404) 1403 302.5 1.7e-81
XP_011534378 (OMIM: 604842) PREDICTED: solute carr ( 404) 1403 302.5 1.7e-81
XP_011534377 (OMIM: 604842) PREDICTED: solute carr ( 404) 1403 302.5 1.7e-81
XP_005267164 (OMIM: 604842) PREDICTED: solute carr ( 337) 1089 237.0 7.4e-62
NP_003051 (OMIM: 212140,603377) solute carrier fam ( 557) 993 217.2 1.1e-55
NP_003050 (OMIM: 180300,604190) solute carrier fam ( 551) 918 201.5 5.7e-51
NP_001171661 (OMIM: 607581) solute carrier family ( 542) 910 199.8 1.8e-50
NP_004245 (OMIM: 607581) solute carrier family 22 ( 542) 910 199.8 1.8e-50
NP_001171662 (OMIM: 607581) solute carrier family ( 451) 898 197.3 8.8e-50
NP_004247 (OMIM: 604047) solute carrier family 22 ( 551) 878 193.2 1.8e-48
NP_149116 (OMIM: 608276) solute carrier family 22 ( 577) 864 190.3 1.4e-47
NP_695008 (OMIM: 607582) solute carrier family 22 ( 550) 841 185.5 3.8e-46
XP_016874051 (OMIM: 607582) PREDICTED: solute carr ( 551) 839 185.1 5.1e-46
NP_004781 (OMIM: 607582) solute carrier family 22 ( 563) 839 185.1 5.2e-46
NP_653186 (OMIM: 220150,607096) solute carrier fam ( 553) 828 182.8 2.5e-45
XP_011534506 (OMIM: 608276) PREDICTED: solute carr ( 534) 822 181.5 5.8e-45
NP_001295051 (OMIM: 212140,603377) solute carrier ( 581) 822 181.5 6.2e-45
XP_011534507 (OMIM: 608276) PREDICTED: solute carr ( 515) 795 175.9 2.8e-43
XP_011543666 (OMIM: 607581) PREDICTED: solute carr ( 419) 787 174.1 7.6e-43
NP_001171665 (OMIM: 607581) solute carrier family ( 419) 787 174.1 7.6e-43
NP_060954 (OMIM: 607097) solute carrier family 22 ( 550) 788 174.4 8.1e-43
NP_006663 (OMIM: 604995) solute carrier family 22 ( 546) 785 173.8 1.2e-42
NP_696961 (OMIM: 604995) solute carrier family 22 ( 548) 771 170.9 9.4e-42
NP_001129978 (OMIM: 611698) solute carrier family ( 552) 747 165.9 3e-40
NP_060890 (OMIM: 608275) solute carrier family 22 ( 547) 724 161.1 8.3e-39
NP_001034841 (OMIM: 607580) solute carrier family ( 541) 711 158.4 5.4e-38
XP_011543318 (OMIM: 607580) PREDICTED: solute carr ( 541) 711 158.4 5.4e-38
XP_016873188 (OMIM: 607580) PREDICTED: solute carr ( 489) 702 156.5 1.8e-37
NP_695010 (OMIM: 607582) solute carrier family 22 ( 519) 698 155.7 3.4e-37
NP_695009 (OMIM: 607582) solute carrier family 22 ( 506) 696 155.2 4.5e-37
XP_006715034 (OMIM: 604995) PREDICTED: solute carr ( 549) 696 155.3 4.7e-37
XP_016865267 (OMIM: 212140,603377) PREDICTED: solu ( 381) 686 153.0 1.5e-36
XP_006715033 (OMIM: 604995) PREDICTED: solute carr ( 551) 683 152.6 3.1e-36
XP_011512559 (OMIM: 604995) PREDICTED: solute carr ( 607) 674 150.7 1.2e-35
XP_016865689 (OMIM: 604995) PREDICTED: solute carr ( 543) 653 146.3 2.3e-34
XP_011512558 (OMIM: 604995) PREDICTED: solute carr ( 610) 653 146.3 2.6e-34
XP_016865687 (OMIM: 604995) PREDICTED: solute carr ( 602) 648 145.3 5.2e-34
XP_011534508 (OMIM: 608276) PREDICTED: solute carr ( 483) 644 144.4 7.9e-34
XP_011512563 (OMIM: 604995) PREDICTED: solute carr ( 420) 643 144.1 8.3e-34
>>NP_003048 (OMIM: 602607) solute carrier family 22 memb (554 aa)
initn: 3725 init1: 3725 opt: 3725 Z-score: 4197.2 bits: 786.4 E(85289): 0
Smith-Waterman score: 3725; 99.8% identity (99.8% similar) in 554 aa overlap (1-554:1-554)
10 20 30 40 50 60
pF1KB9 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
490 500 510 520 530 540
550
pF1KB9 TIYLKVQTSEPSGT
::::::::::::::
NP_003 TIYLKVQTSEPSGT
550
>>XP_005267160 (OMIM: 602607) PREDICTED: solute carrier (573 aa)
initn: 3388 init1: 3388 opt: 3388 Z-score: 3817.5 bits: 716.2 E(85289): 6.8e-206
Smith-Waterman score: 3388; 99.8% identity (99.8% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KB9 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
:::::::::::::::::::
XP_005 PFIVFRLREVWQALPLILFGQRTSKTLLTHLIEDNSCWLFAEPAMPGHSGVGPACRGSDA
490 500 510 520 530 540
>>XP_005267159 (OMIM: 602607) PREDICTED: solute carrier (610 aa)
initn: 3388 init1: 3388 opt: 3388 Z-score: 3817.1 bits: 716.2 E(85289): 7.1e-206
Smith-Waterman score: 3388; 99.8% identity (99.8% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KB9 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
:::::::::::::::::::
XP_005 PFIVFRLREVWQALPLILFEKQSPKKTRFTLRSKPQNPRAPERDVLRRCRVGGMKMELSS
490 500 510 520 530 540
>>NP_694857 (OMIM: 602607) solute carrier family 22 memb (506 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 3534.4 bits: 663.7 E(85289): 4e-190
Smith-Waterman score: 3136; 99.1% identity (99.6% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KB9 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
::::::::::::::::::::::::::::::::::::::::: ..:
NP_694 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPACRGSDATSSRDQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
NP_694 GRFARDHEGRREPWEKSKAQRKHDLP
490 500
>>XP_006715615 (OMIM: 602607) PREDICTED: solute carrier (483 aa)
initn: 3135 init1: 3135 opt: 3135 Z-score: 3533.5 bits: 663.4 E(85289): 4.4e-190
Smith-Waterman score: 3135; 99.8% identity (99.8% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KB9 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
::::::::::::::::::::::::::::::::::::::::::
XP_006 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRKAKPKENTIYLKVQTSEP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
XP_006 SGT
>>NP_003049 (OMIM: 602608) solute carrier family 22 memb (555 aa)
initn: 2709 init1: 2709 opt: 2714 Z-score: 3058.6 bits: 575.8 E(85289): 1.3e-163
Smith-Waterman score: 2714; 70.6% identity (90.1% similar) in 548 aa overlap (1-547:1-548)
10 20 30 40 50
pF1KB9 MPT-VDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELS
::: :::.::. :: .:::: :..: ::::.:::: ::::::::::::.:.::::::::
NP_003 MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 QCCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLG
::::::::::::::: :::::: ::::::::::::...:::::::: ::::.::::
NP_003 LRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PCQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCL
::.:::::.:::::::::::::::.:: :::::: .:.::..::...::.::::::::::
NP_003 PCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 LGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIM
: :::.::..:::::.::.: ::.:::.::::::..:. :: ::::::: ::::.:.
NP_003 LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 YQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI
::.:.::::..:.:.:::::::::::..::::.:.:::::::.:::::::.::..:.::.
NP_003 YQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 KIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSV
.:. :::.:::: ::.:. : :::.. .::.::: :: :::..::.:.:::: :::.::
NP_003 RIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 LYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLV
::::::.::: .. :.::::.::::::.:.::. ..::::.:: :: : ::..::::::.
NP_003 LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 MIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGII
.:: ::.::.::: :.::::::.: ...:::::::::::.::::: .:::.:::::::
NP_003 SVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGII
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 TPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKE
:::.:.:: ..: :::..:.::::.:.:..:::::::: :::::...:::. : : ::
NP_003 TPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKE
490 500 510 520 530 540
540 550
pF1KB9 NTIYLKVQTSEPSGT
. :::.::
NP_003 KMIYLQVQKLDIPLN
550
>>XP_005267162 (OMIM: 602607) PREDICTED: solute carrier (418 aa)
initn: 2046 init1: 2046 opt: 2046 Z-score: 2308.0 bits: 436.5 E(85289): 8.1e-122
Smith-Waterman score: 2046; 100.0% identity (100.0% similar) in 307 aa overlap (193-499:1-307)
170 180 190 200 210 220
pF1KB9 SLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYT
::::::::::::::::::::::::::::::
XP_005 MAFSPNYMSMLLFRLLQGLVSKGNWMAGYT
10 20 30
230 240 250 260 270 280
pF1KB9 LITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCV
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB9 PESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPR
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB9 LRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGR
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB9 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVR
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB9 NLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALP
:::::::::::::::::::::::::::::::::::::
XP_005 NLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFEKQSPKKTRFTLRSKPQNPRAPE
280 290 300 310 320 330
530 540 550
pF1KB9 ETMKDAENLGRKAKPKENTIYLKVQTSEPSGT
XP_005 RDVLRRCRVGGMKMELSSAEIPRRLHFSVFFLILAYPQINISPKEWFVWALSYFVFFLLS
340 350 360 370 380 390
>>XP_005267161 (OMIM: 602607) PREDICTED: solute carrier (418 aa)
initn: 2046 init1: 2046 opt: 2046 Z-score: 2308.0 bits: 436.5 E(85289): 8.1e-122
Smith-Waterman score: 2046; 100.0% identity (100.0% similar) in 307 aa overlap (193-499:1-307)
170 180 190 200 210 220
pF1KB9 SLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYT
::::::::::::::::::::::::::::::
XP_005 MAFSPNYMSMLLFRLLQGLVSKGNWMAGYT
10 20 30
230 240 250 260 270 280
pF1KB9 LITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCV
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB9 PESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPR
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB9 LRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGR
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB9 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVR
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB9 NLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALP
:::::::::::::::::::::::::::::::::::::
XP_005 NLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFEKQSPKKTRFTLRSKPQNPRAPE
280 290 300 310 320 330
530 540 550
pF1KB9 ETMKDAENLGRKAKPKENTIYLKVQTSEPSGT
XP_005 RDVLRRCRVGGMKMELSSAEIPRRLHFSVFFLILAYPQINISPKEWFVWALSYFVFFLLS
340 350 360 370 380 390
>>XP_011534376 (OMIM: 602607) PREDICTED: solute carrier (418 aa)
initn: 2046 init1: 2046 opt: 2046 Z-score: 2308.0 bits: 436.5 E(85289): 8.1e-122
Smith-Waterman score: 2046; 100.0% identity (100.0% similar) in 307 aa overlap (193-499:1-307)
170 180 190 200 210 220
pF1KB9 SLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYT
::::::::::::::::::::::::::::::
XP_011 MAFSPNYMSMLLFRLLQGLVSKGNWMAGYT
10 20 30
230 240 250 260 270 280
pF1KB9 LITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCV
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB9 PESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPR
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB9 LRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGR
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB9 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVR
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB9 NLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALP
:::::::::::::::::::::::::::::::::::::
XP_011 NLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFEKQSPKKTRFTLRSKPQNPRAPE
280 290 300 310 320 330
530 540 550
pF1KB9 ETMKDAENLGRKAKPKENTIYLKVQTSEPSGT
XP_011 RDVLRRCRVGGMKMELSSAEIPRRLHFSVFFLILAYPQINISPKEWFVWALSYFVFFLLS
340 350 360 370 380 390
>>NP_068812 (OMIM: 604842) solute carrier family 22 memb (556 aa)
initn: 1775 init1: 807 opt: 1884 Z-score: 2123.9 bits: 402.8 E(85289): 1.4e-111
Smith-Waterman score: 1884; 50.2% identity (78.7% similar) in 540 aa overlap (1-532:1-536)
10 20 30 40 50
pF1KB9 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHH-CQSPGVAELS
::. :. :..::: : ::...::.::: ...:: . ::.:::: :::. :..:..: :.
NP_068 MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 QCCGWSPAEELNYTVPGL-GPAGEAFLGQCRRYEVDWNQ------SALSCVDPLASLATN
. ::::: :: : :.:. :: :.:.:: .. . :::::.::::.. :
NP_068 ERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFP-N
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 RSHLPLGPCQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADR
:: :: ::. :: : :.::.::.:::...: ::: :. :: ::: :.. .:: :::
NP_068 RSA-PLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 FGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGS
.:: . : . : .:.::..::.::. ...::.:::. .::.::. :...::.::: .
NP_068 YGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 RRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQ
:: :.:. :: ::.:.. : :.:: .:.:. .:::..::.:::::::: ::::::::...
NP_068 RRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 KRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMY
:.. .:..:. .::. ::: .. . ... .. : .::: :: :::..:: :.:::.
NP_068 KKGDKALQILRRIAKCNGKYLSSNYSEITVTDE--EVSNPSFLDLVRTPQMRKCTLILMF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 LWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL
:::..:.::::....: .::::.::. :..::.:::.. :.::.:.:: :.: ::..
NP_068 AWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSL
::.:::: :. . :: . .::.:::.:.... :::.::::: .::.:: .::.:
NP_068 AGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB9 CDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLG
::.::::.::..::: :: ::::.:..:. . .:...:::::::.:::::. :.:.::
NP_068 CDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLG
480 490 500 510 520 530
540 550
pF1KB9 RKAKPKENTIYLKVQTSEPSGT
NP_068 SPHSCKCGRNKKTPVSRSHL
540 550
554 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:46:49 2016 done: Sat Nov 5 17:46:50 2016
Total Scan time: 9.570 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]