Result of FASTA (omim) for pF1KB9972
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9972, 704 aa
  1>>>pF1KB9972 704 - 704 aa - 704 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7493+/-0.000469; mu= 18.3908+/- 0.029
 mean_var=87.3736+/-17.404, 0's: 0 Z-trim(110.7): 18  B-trim: 406 in 1/51
 Lambda= 0.137209
 statistics sampled from 19098 (19112) to 19098 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.224), width:  16
 Scan time: 10.590

The best scores are:                                      opt bits E(85289)
NP_057376 (OMIM: 606219) heat shock protein 75 kDa ( 704) 4538 909.1       0
NP_001258978 (OMIM: 606219) heat shock protein 75  ( 651) 3993 801.2       0
XP_011520647 (OMIM: 606219) PREDICTED: heat shock  ( 564) 3639 731.1 2.8e-210
XP_016878340 (OMIM: 606219) PREDICTED: heat shock  ( 405) 2625 530.3 5.8e-150
NP_001258900 (OMIM: 140572) heat shock protein HSP ( 676)  628 135.1 8.6e-31
NP_001258901 (OMIM: 140572) heat shock protein HSP ( 714)  628 135.1   9e-31
NP_031381 (OMIM: 140572) heat shock protein HSP 90 ( 724)  628 135.1 9.1e-31
NP_001258899 (OMIM: 140572) heat shock protein HSP ( 724)  628 135.1 9.1e-31
NP_001258898 (OMIM: 140572) heat shock protein HSP ( 724)  628 135.1 9.1e-31
NP_005339 (OMIM: 140571) heat shock protein HSP 90 ( 732)  626 134.7 1.2e-30
XP_011535020 (OMIM: 140571) PREDICTED: heat shock  ( 853)  626 134.8 1.4e-30
NP_001017963 (OMIM: 140571) heat shock protein HSP ( 854)  626 134.8 1.4e-30
NP_003290 (OMIM: 191175) endoplasmin precursor [Ho ( 803)  561 121.9 9.7e-27


>>NP_057376 (OMIM: 606219) heat shock protein 75 kDa, mi  (704 aa)
 initn: 4538 init1: 4538 opt: 4538  Z-score: 4856.5  bits: 909.1 E(85289):    0
Smith-Waterman score: 4538; 100.0% identity (100.0% similar) in 704 aa overlap (1-704:1-704)

               10        20        30        40        50        60
pF1KB9 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS
              610       620       630       640       650       660

              670       680       690       700    
pF1KB9 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH
       ::::::::::::::::::::::::::::::::::::::::::::
NP_057 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH
              670       680       690       700    

>>NP_001258978 (OMIM: 606219) heat shock protein 75 kDa,  (651 aa)
 initn: 3993 init1: 3993 opt: 3993  Z-score: 4273.9  bits: 801.2 E(85289):    0
Smith-Waterman score: 4068; 92.5% identity (92.5% similar) in 704 aa overlap (1-704:1-651)

               10        20        30        40        50        60
pF1KB9 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFS
       ::::::::::::::::::::::::::::::                              
NP_001 MARELRALLLWGRRLRPLLRAPALAAVPGG------------------------------
               10        20        30                              

               70        80        90       100       110       120
pF1KB9 TQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA
                              :::::::::::::::::::::::::::::::::::::
NP_001 -----------------------STSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA
                                      40        50        60       

              130       140       150       160       170       180
pF1KB9 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS
        70        80        90       100       110       120       

              190       200       210       220       230       240
pF1KB9 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE
       130       140       150       160       170       180       

              250       260       270       280       290       300
pF1KB9 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM
       190       200       210       220       230       240       

              310       320       330       340       350       360
pF1KB9 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG
       250       260       270       280       290       300       

              370       380       390       400       410       420
pF1KB9 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ
       310       320       330       340       350       360       

              430       440       450       460       470       480
pF1KB9 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL
       370       380       390       400       410       420       

              490       500       510       520       530       540
pF1KB9 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR
       430       440       450       460       470       480       

              550       560       570       580       590       600
pF1KB9 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT
       490       500       510       520       530       540       

              610       620       630       640       650       660
pF1KB9 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS
       550       560       570       580       590       600       

              670       680       690       700    
pF1KB9 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH
       610       620       630       640       650 

>>XP_011520647 (OMIM: 606219) PREDICTED: heat shock prot  (564 aa)
 initn: 3639 init1: 3639 opt: 3639  Z-score: 3896.1  bits: 731.1 E(85289): 2.8e-210
Smith-Waterman score: 3639; 100.0% identity (100.0% similar) in 564 aa overlap (141-704:1-564)

              120       130       140       150       160       170
pF1KB9 VFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVS
                                     ::::::::::::::::::::::::::::::
XP_011                               MEIHLQTNAEKGTITIQDTGIGMTQEELVS
                                             10        20        30

              180       190       200       210       220       230
pF1KB9 NLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQ
               40        50        60        70        80        90

              240       250       260       270       280       290
pF1KB9 WLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGR
              100       110       120       130       140       150

              300       310       320       330       340       350
pF1KB9 RMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKP
              160       170       180       190       200       210

              360       370       380       390       400       410
pF1KB9 SMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL
              220       230       240       250       260       270

              420       430       440       450       460       470
pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY
              280       290       300       310       320       330

              480       490       500       510       520       530
pF1KB9 ESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQ
              340       350       360       370       380       390

              540       550       560       570       580       590
pF1KB9 FDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVL
              400       410       420       430       440       450

              600       610       620       630       640       650
pF1KB9 GSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHAL
              460       470       480       490       500       510

              660       670       680       690       700    
pF1KB9 IKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH
              520       530       540       550       560    

>>XP_016878340 (OMIM: 606219) PREDICTED: heat shock prot  (405 aa)
 initn: 2625 init1: 2625 opt: 2625  Z-score: 2813.3  bits: 530.3 E(85289): 5.8e-150
Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 405 aa overlap (300-704:1-405)

     270       280       290       300       310       320         
pF1KB9 VRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTL
                                     ::::::::::::::::::::::::::::::
XP_016                               MMDPKDVREWQHEEFYRYVAQAHDKPRYTL
                                             10        20        30

     330       340       350       360       370       380         
pF1KB9 HYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRG
               40        50        60        70        80        90

     390       400       410       420       430       440         
pF1KB9 VVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMR
              100       110       120       130       140       150

     450       460       470       480       490       500         
pF1KB9 EGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAE
              160       170       180       190       200       210

     510       520       530       540       550       560         
pF1KB9 HSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSP
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KB9 AAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAK
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KB9 TQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAM
              340       350       360       370       380       390

     690       700    
pF1KB9 VGRLNELLVKALERH
       :::::::::::::::
XP_016 VGRLNELLVKALERH
              400     

>>NP_001258900 (OMIM: 140572) heat shock protein HSP 90-  (676 aa)
 initn: 884 init1: 289 opt: 628  Z-score: 673.8  bits: 135.1 E(85289): 8.6e-31
Smith-Waterman score: 867; 27.9% identity (57.9% similar) in 681 aa overlap (90-697:17-636)

      60        70        80        90       100       110         
pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
                                     ::::  .:....  ..::.::.:.::::::
NP_001               MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN
                             10        20        30        40      

     120       130       140       150       160       170         
pF1KB9 ASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSG
       :::::.:.:.. ..: . :                   :.:     .::  ...      
NP_001 ASDALDKIRYESLTDPSKL-------------------DSG-----KELKIDIS------
         50        60                                70            

     180       190       200       210       220       230         
pF1KB9 SKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVF
                        .:::::::::::..::..: : ..     .  : : :...: :
NP_001 -----------------MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAGGSF
                          80        90       100         110       

     240         250       260       270       280         290     
pF1KB9 EIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR----
        .    :  .  :::.:.::: :  :.  : ::..:: :.:.:...:  :::. .:    
NP_001 TVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEI
       120       130       140       150       160       170       

                                                                   
pF1KB9 --------------------------------------------------------MNTL
                                                               .:  
NP_001 SDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKT
       180       190       200       210       220       230       

         300       310       320       330       340       350     
pF1KB9 QAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDV
       . ::  .: :. . .. :::. ...  .    . :..... :..:.....:   :  ::.
NP_001 KPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP--FDL
       240       250       260       270       280       290       

           360       370       380       390       400       410   
pF1KB9 --SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRK
         ...  ... :: :.:.:. .  ...:..: ::::::::::.:::.:::.::.: ... 
NP_001 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV
         300       310       320       330       340       350     

           420       430       440       450       460       470   
pF1KB9 LRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESS
       .:  . .. ...: . .. : :.: ::.: ..  .. ::    ..  .. ...::::..:
NP_001 IRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRYHTS
         360       370        380       390         400       410  

            480       490       500       510       520       530  
pF1KB9 ALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFD
          :: ..::::::.:::.   ..:::. . ... . .: . : ..:.  ::..  : .:
NP_001 --QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPID
              420       430       440       450       460       470

            540       550       560       570       580       590  
pF1KB9 ELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGS
       :  . .:.::: :.:.::  . .  .  :.. :...   :  :. . :.:   :...: .
NP_001 EYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEILDK
              480       490          500         510       520     

            600       610          620       630       640         
pF1KB9 RVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINPRHA
       .: .: .. :: . :  ...  .:     ..... : :  ..    .. .  ::::: : 
NP_001 KVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHP
         530       540       550       560       570       580     

     650       660         670       680        690       700      
pF1KB9 LIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALERH  
       ... : :   .. .   .. ::  ..:.:....:. ..::..  .:. ...         
NP_001 IVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED
         590       600       610       620       630       640     

NP_001 EVAAEEPNAAVPDEIPPLEGDEDASRMEEVD
         650       660       670      

>>NP_001258901 (OMIM: 140572) heat shock protein HSP 90-  (714 aa)
 initn: 869 init1: 289 opt: 628  Z-score: 673.4  bits: 135.1 E(85289): 9e-31
Smith-Waterman score: 1072; 30.7% identity (61.8% similar) in 684 aa overlap (90-697:17-674)

      60        70        80        90       100       110         
pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
                                     ::::  .:....  ..::.::.:.::::::
NP_001               MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN
                             10        20        30        40      

     120       130          140       150       160       170      
pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA
       :::::.:.:.. ..: . :    :..: .  : .. :.:. :::::::. .:..::::::
NP_001 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA
         50        60        70        80        90       100      

        180       190       200       210       220       230      
pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS
       .::.:::..:::            ::::::::..::..: : ..     .  : : :...
NP_001 KSGTKAFMEALQ------------FGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG
        110                   120       130       140         150  

        240         250       260       270       280         290  
pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR-
       : : .    :  .  :::.:.::: :  :.  : ::..:: :.:.:...:  :::. .: 
NP_001 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE
            160       170       180       190       200       210  

                                                                   
pF1KB9 -----------------------------------------------------------M
                                                                  .
NP_001 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL
            220       230       240       250       260       270  

            300       310       320       330       340       350  
pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM
       :  . ::  .: :. . .. :::. ...  .    . :..... :..:.....:   :  
NP_001 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP--
            280       290       300       310       320       330  

              360       370       380       390       400       410
pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL
       ::.  ...  ... :: :.:.:. .  ...:..: ::::::::::.:::.:::.::.: .
NP_001 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI
              340       350       360       370       380       390

              420       430       440       450       460       470
pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY
       .. .:  . .. ...: . .. : :.: ::.: ..  .. ::    ..  .. ...::::
NP_001 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY
              400       410        420       430         440       

               480       490       500       510       520         
pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE
       ..:   :: ..::::::.:::.   ..:::. . ... . .: . : ..:.  ::..  :
NP_001 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE
       450         460       470       480       490       500     

     530       540       550       560       570       580         
pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV
        .::  . .:.::: :.:.::  . .  .  :.. :...   :  :. . :.:   :...
NP_001 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI
         510       520       530          540         550       560

     590       600       610          620       630       640      
pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP
       : ..: .: .. :: . :  ...  .:     ..... : :  ..    .. .  :::::
NP_001 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP
              570       580       590       600       610       620

        650       660         670       680        690       700   
pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER
        : ... : :   .. .   .. ::  ..:.:....:. ..::..  .:. ...      
NP_001 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI
              630       640       650       660       670       680

                                         
pF1KB9 H                                 
                                         
NP_001 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD
              690       700       710    

>>NP_031381 (OMIM: 140572) heat shock protein HSP 90-bet  (724 aa)
 initn: 895 init1: 289 opt: 628  Z-score: 673.3  bits: 135.1 E(85289): 9.1e-31
Smith-Waterman score: 1122; 31.4% identity (62.9% similar) in 684 aa overlap (90-697:17-684)

      60        70        80        90       100       110         
pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
                                     ::::  .:....  ..::.::.:.::::::
NP_031               MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN
                             10        20        30        40      

     120       130          140       150       160       170      
pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA
       :::::.:.:.. ..: . :    :..: .  : .. :.:. :::::::. .:..::::::
NP_031 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA
         50        60        70        80        90       100      

        180       190       200       210       220       230      
pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS
       .::.:::..:::  :. :  .:::::::::::..::..: : ..     .  : : :...
NP_031 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG
        110       120         130       140       150         160  

        240         250       260       270       280         290  
pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR-
       : : .    :  .  :::.:.::: :  :.  : ::..:: :.:.:...:  :::. .: 
NP_031 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE
            170       180       190       200       210       220  

                                                                   
pF1KB9 -----------------------------------------------------------M
                                                                  .
NP_031 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL
            230       240       250       260       270       280  

            300       310       320       330       340       350  
pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM
       :  . ::  .: :. . .. :::. ...  .    . :..... :..:.....:   :  
NP_031 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP--
            290       300       310       320       330       340  

              360       370       380       390       400       410
pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL
       ::.  ...  ... :: :.:.:. .  ...:..: ::::::::::.:::.:::.::.: .
NP_031 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI
              350       360       370       380       390       400

              420       430       440       450       460       470
pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY
       .. .:  . .. ...: . .. : :.: ::.: ..  .. ::    ..  .. ...::::
NP_031 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY
              410       420        430       440         450       

               480       490       500       510       520         
pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE
       ..:   :: ..::::::.:::.   ..:::. . ... . .: . : ..:.  ::..  :
NP_031 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE
       460         470       480       490       500       510     

     530       540       550       560       570       580         
pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV
        .::  . .:.::: :.:.::  . .  .  :.. :...   :  :. . :.:   :...
NP_031 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI
         520       530       540          550         560       570

     590       600       610          620       630       640      
pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP
       : ..: .: .. :: . :  ...  .:     ..... : :  ..    .. .  :::::
NP_031 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP
              580       590       600       610       620       630

        650       660         670       680        690       700   
pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER
        : ... : :   .. .   .. ::  ..:.:....:. ..::..  .:. ...      
NP_031 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI
              640       650       660       670       680       690

                                         
pF1KB9 H                                 
                                         
NP_031 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD
              700       710       720    

>>NP_001258899 (OMIM: 140572) heat shock protein HSP 90-  (724 aa)
 initn: 895 init1: 289 opt: 628  Z-score: 673.3  bits: 135.1 E(85289): 9.1e-31
Smith-Waterman score: 1122; 31.4% identity (62.9% similar) in 684 aa overlap (90-697:17-684)

      60        70        80        90       100       110         
pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
                                     ::::  .:....  ..::.::.:.::::::
NP_001               MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN
                             10        20        30        40      

     120       130          140       150       160       170      
pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA
       :::::.:.:.. ..: . :    :..: .  : .. :.:. :::::::. .:..::::::
NP_001 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA
         50        60        70        80        90       100      

        180       190       200       210       220       230      
pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS
       .::.:::..:::  :. :  .:::::::::::..::..: : ..     .  : : :...
NP_001 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG
        110       120         130       140       150         160  

        240         250       260       270       280         290  
pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR-
       : : .    :  .  :::.:.::: :  :.  : ::..:: :.:.:...:  :::. .: 
NP_001 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE
            170       180       190       200       210       220  

                                                                   
pF1KB9 -----------------------------------------------------------M
                                                                  .
NP_001 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL
            230       240       250       260       270       280  

            300       310       320       330       340       350  
pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM
       :  . ::  .: :. . .. :::. ...  .    . :..... :..:.....:   :  
NP_001 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP--
            290       300       310       320       330       340  

              360       370       380       390       400       410
pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL
       ::.  ...  ... :: :.:.:. .  ...:..: ::::::::::.:::.:::.::.: .
NP_001 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI
              350       360       370       380       390       400

              420       430       440       450       460       470
pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY
       .. .:  . .. ...: . .. : :.: ::.: ..  .. ::    ..  .. ...::::
NP_001 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY
              410       420        430       440         450       

               480       490       500       510       520         
pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE
       ..:   :: ..::::::.:::.   ..:::. . ... . .: . : ..:.  ::..  :
NP_001 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE
       460         470       480       490       500       510     

     530       540       550       560       570       580         
pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV
        .::  . .:.::: :.:.::  . .  .  :.. :...   :  :. . :.:   :...
NP_001 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI
         520       530       540          550         560       570

     590       600       610          620       630       640      
pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP
       : ..: .: .. :: . :  ...  .:     ..... : :  ..    .. .  :::::
NP_001 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP
              580       590       600       610       620       630

        650       660         670       680        690       700   
pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER
        : ... : :   .. .   .. ::  ..:.:....:. ..::..  .:. ...      
NP_001 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI
              640       650       660       670       680       690

                                         
pF1KB9 H                                 
                                         
NP_001 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD
              700       710       720    

>>NP_001258898 (OMIM: 140572) heat shock protein HSP 90-  (724 aa)
 initn: 895 init1: 289 opt: 628  Z-score: 673.3  bits: 135.1 E(85289): 9.1e-31
Smith-Waterman score: 1122; 31.4% identity (62.9% similar) in 684 aa overlap (90-697:17-684)

      60        70        80        90       100       110         
pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
                                     ::::  .:....  ..::.::.:.::::::
NP_001               MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN
                             10        20        30        40      

     120       130          140       150       160       170      
pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA
       :::::.:.:.. ..: . :    :..: .  : .. :.:. :::::::. .:..::::::
NP_001 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA
         50        60        70        80        90       100      

        180       190       200       210       220       230      
pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS
       .::.:::..:::  :. :  .:::::::::::..::..: : ..     .  : : :...
NP_001 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG
        110       120         130       140       150         160  

        240         250       260       270       280         290  
pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR-
       : : .    :  .  :::.:.::: :  :.  : ::..:: :.:.:...:  :::. .: 
NP_001 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE
            170       180       190       200       210       220  

                                                                   
pF1KB9 -----------------------------------------------------------M
                                                                  .
NP_001 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL
            230       240       250       260       270       280  

            300       310       320       330       340       350  
pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM
       :  . ::  .: :. . .. :::. ...  .    . :..... :..:.....:   :  
NP_001 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP--
            290       300       310       320       330       340  

              360       370       380       390       400       410
pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL
       ::.  ...  ... :: :.:.:. .  ...:..: ::::::::::.:::.:::.::.: .
NP_001 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI
              350       360       370       380       390       400

              420       430       440       450       460       470
pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY
       .. .:  . .. ...: . .. : :.: ::.: ..  .. ::    ..  .. ...::::
NP_001 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY
              410       420        430       440         450       

               480       490       500       510       520         
pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE
       ..:   :: ..::::::.:::.   ..:::. . ... . .: . : ..:.  ::..  :
NP_001 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE
       460         470       480       490       500       510     

     530       540       550       560       570       580         
pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV
        .::  . .:.::: :.:.::  . .  .  :.. :...   :  :. . :.:   :...
NP_001 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI
         520       530       540          550         560       570

     590       600       610          620       630       640      
pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP
       : ..: .: .. :: . :  ...  .:     ..... : :  ..    .. .  :::::
NP_001 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP
              580       590       600       610       620       630

        650       660         670       680        690       700   
pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER
        : ... : :   .. .   .. ::  ..:.:....:. ..::..  .:. ...      
NP_001 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI
              640       650       660       670       680       690

                                         
pF1KB9 H                                 
                                         
NP_001 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD
              700       710       720    

>>NP_005339 (OMIM: 140571) heat shock protein HSP 90-alp  (732 aa)
 initn: 993 init1: 306 opt: 626  Z-score: 671.1  bits: 134.7 E(85289): 1.2e-30
Smith-Waterman score: 1113; 31.3% identity (62.9% similar) in 690 aa overlap (90-697:22-692)

      60        70        80        90       100       110         
pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
                                     ::::  .:....  ..::.::.:.::::::
NP_005          MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN
                        10        20        30        40        50 

     120       130          140       150       160       170      
pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA
       .::::.:.:.. ..: . :    :..:.:  : .  :.:: :::::::. .:..::::::
NP_005 SSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIA
              60        70        80        90       100       110 

        180       190       200       210       220       230      
pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS
       .::.:::..:::  :. :  .:::::::::::..::..: : ..     .  : : :...
NP_005 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVTVITKHNDDEQ--YAWESSAG
             120         130       140       150         160       

        240         250       260       270       280              
pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPL---------
       : : .   .:  .  :::.:.::: :  :.  : :....: :.:.:...:.         
NP_005 GSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERD
       170       180       190       200       210       220       

                                                                   
pF1KB9 --------------------------------------------------------YLNG
                                                               :.. 
NP_005 KEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQ
       230       240       250       260       270       280       

     290       300       310       320       330       340         
pF1KB9 RRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMK
       ...:  . ::  .: :. . .. :::. ...  .    . :..... :..:....::   
NP_005 EELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRA
       290       300       310       320       330       340       

     350         360       370       380       390       400       
pF1KB9 PSMFDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQE
       :  ::.  .:.  ... :: :.:.:. .  ...:..: ::::::::::.:::.:::.::.
NP_005 P--FDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ
         350       360       370       380       390       400     

       410       420       430       440       450       460       
pF1KB9 SALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKL
       : ... .:  : .. ...: . .. : :.: ::.:...  .. ::    ... .. ...:
NP_005 SKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKLSEL
         410       420        430       440         450       460  

       470        480       490       500       510       520      
pF1KB9 LRYESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLF
       ::: .::  :: ...::..: .::. . ..:::. . ..  . .: . : ..:.  ::..
NP_005 LRYYTSA--SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIY
              470       480       490       500       510       520

        530       540       550        560       570         580   
pF1KB9 CFEQFDELTLLHLREFDKKKLISVETD-IVVDHYKEEKFEDRSPAAECLSEKET--EELM
        .: .::  . .:.::. : :.::  . . . . .::: ...        ::.:  :.: 
NP_005 MIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQE--------EKKTKFENLC
              530       540       550       560               570  

           590       600       610          620       630       640
pF1KB9 AWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQP
         :...: ..: .: :. :: : :  ...  .:     ..... : :  ..    .  . 
NP_005 KIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKK
            580       590       600       610       620       630  

              650       660         670       680        690       
pF1KB9 TLEINPRHALIKKLNQLRASEPGLAQL--LVDQIYENAMIAAGL-VDDPRAMVGRLNELL
        ::::: :..:. : :   .. .  ..  ::  .::.:....:. ..::.. ..:. ...
NP_005 HLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMI
            640       650       660       670       680       690  

       700                                     
pF1KB9 VKALERH                                 
                                               
NP_005 KLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD
            700       710       720       730  




704 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:02:54 2016 done: Fri Nov  4 09:02:56 2016
 Total Scan time: 10.590 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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