FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9972, 704 aa 1>>>pF1KB9972 704 - 704 aa - 704 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7493+/-0.000469; mu= 18.3908+/- 0.029 mean_var=87.3736+/-17.404, 0's: 0 Z-trim(110.7): 18 B-trim: 406 in 1/51 Lambda= 0.137209 statistics sampled from 19098 (19112) to 19098 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.224), width: 16 Scan time: 10.590 The best scores are: opt bits E(85289) NP_057376 (OMIM: 606219) heat shock protein 75 kDa ( 704) 4538 909.1 0 NP_001258978 (OMIM: 606219) heat shock protein 75 ( 651) 3993 801.2 0 XP_011520647 (OMIM: 606219) PREDICTED: heat shock ( 564) 3639 731.1 2.8e-210 XP_016878340 (OMIM: 606219) PREDICTED: heat shock ( 405) 2625 530.3 5.8e-150 NP_001258900 (OMIM: 140572) heat shock protein HSP ( 676) 628 135.1 8.6e-31 NP_001258901 (OMIM: 140572) heat shock protein HSP ( 714) 628 135.1 9e-31 NP_031381 (OMIM: 140572) heat shock protein HSP 90 ( 724) 628 135.1 9.1e-31 NP_001258899 (OMIM: 140572) heat shock protein HSP ( 724) 628 135.1 9.1e-31 NP_001258898 (OMIM: 140572) heat shock protein HSP ( 724) 628 135.1 9.1e-31 NP_005339 (OMIM: 140571) heat shock protein HSP 90 ( 732) 626 134.7 1.2e-30 XP_011535020 (OMIM: 140571) PREDICTED: heat shock ( 853) 626 134.8 1.4e-30 NP_001017963 (OMIM: 140571) heat shock protein HSP ( 854) 626 134.8 1.4e-30 NP_003290 (OMIM: 191175) endoplasmin precursor [Ho ( 803) 561 121.9 9.7e-27 >>NP_057376 (OMIM: 606219) heat shock protein 75 kDa, mi (704 aa) initn: 4538 init1: 4538 opt: 4538 Z-score: 4856.5 bits: 909.1 E(85289): 0 Smith-Waterman score: 4538; 100.0% identity (100.0% similar) in 704 aa overlap (1-704:1-704) 10 20 30 40 50 60 pF1KB9 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 TQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS 610 620 630 640 650 660 670 680 690 700 pF1KB9 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH :::::::::::::::::::::::::::::::::::::::::::: NP_057 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 670 680 690 700 >>NP_001258978 (OMIM: 606219) heat shock protein 75 kDa, (651 aa) initn: 3993 init1: 3993 opt: 3993 Z-score: 4273.9 bits: 801.2 E(85289): 0 Smith-Waterman score: 4068; 92.5% identity (92.5% similar) in 704 aa overlap (1-704:1-651) 10 20 30 40 50 60 pF1KB9 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFS :::::::::::::::::::::::::::::: NP_001 MARELRALLLWGRRLRPLLRAPALAAVPGG------------------------------ 10 20 30 70 80 90 100 110 120 pF1KB9 TQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA ::::::::::::::::::::::::::::::::::::: NP_001 -----------------------STSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNA 40 50 60 130 140 150 160 170 180 pF1KB9 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGS 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB9 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFE 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB9 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWM 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB9 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELG 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB9 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQ 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB9 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL 370 380 390 400 410 420 490 500 510 520 530 540 pF1KB9 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLR 430 440 450 460 470 480 550 560 570 580 590 600 pF1KB9 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVT 490 500 510 520 530 540 610 620 630 640 650 660 pF1KB9 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRAS 550 560 570 580 590 600 670 680 690 700 pF1KB9 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH :::::::::::::::::::::::::::::::::::::::::::: NP_001 EPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 610 620 630 640 650 >>XP_011520647 (OMIM: 606219) PREDICTED: heat shock prot (564 aa) initn: 3639 init1: 3639 opt: 3639 Z-score: 3896.1 bits: 731.1 E(85289): 2.8e-210 Smith-Waterman score: 3639; 100.0% identity (100.0% similar) in 564 aa overlap (141-704:1-564) 120 130 140 150 160 170 pF1KB9 VFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVS :::::::::::::::::::::::::::::: XP_011 MEIHLQTNAEKGTITIQDTGIGMTQEELVS 10 20 30 180 190 200 210 220 230 pF1KB9 NLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQ 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB9 WLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGR 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB9 RMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKP 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB9 SMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL 220 230 240 250 260 270 420 430 440 450 460 470 pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY 280 290 300 310 320 330 480 490 500 510 520 530 pF1KB9 ESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQ 340 350 360 370 380 390 540 550 560 570 580 590 pF1KB9 FDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVL 400 410 420 430 440 450 600 610 620 630 640 650 pF1KB9 GSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHAL 460 470 480 490 500 510 660 670 680 690 700 pF1KB9 IKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 520 530 540 550 560 >>XP_016878340 (OMIM: 606219) PREDICTED: heat shock prot (405 aa) initn: 2625 init1: 2625 opt: 2625 Z-score: 2813.3 bits: 530.3 E(85289): 5.8e-150 Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 405 aa overlap (300-704:1-405) 270 280 290 300 310 320 pF1KB9 VRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTL :::::::::::::::::::::::::::::: XP_016 MMDPKDVREWQHEEFYRYVAQAHDKPRYTL 10 20 30 330 340 350 360 370 380 pF1KB9 HYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRG 40 50 60 70 80 90 390 400 410 420 430 440 pF1KB9 VVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMR 100 110 120 130 140 150 450 460 470 480 490 500 pF1KB9 EGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAE 160 170 180 190 200 210 510 520 530 540 550 560 pF1KB9 HSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSP 220 230 240 250 260 270 570 580 590 600 610 620 pF1KB9 AAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAK 280 290 300 310 320 330 630 640 650 660 670 680 pF1KB9 TQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAM 340 350 360 370 380 390 690 700 pF1KB9 VGRLNELLVKALERH ::::::::::::::: XP_016 VGRLNELLVKALERH 400 >>NP_001258900 (OMIM: 140572) heat shock protein HSP 90- (676 aa) initn: 884 init1: 289 opt: 628 Z-score: 673.8 bits: 135.1 E(85289): 8.6e-31 Smith-Waterman score: 867; 27.9% identity (57.9% similar) in 681 aa overlap (90-697:17-636) 60 70 80 90 100 110 pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN :::: .:.... ..::.::.:.:::::: NP_001 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN 10 20 30 40 120 130 140 150 160 170 pF1KB9 ASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSG :::::.:.:.. ..: . : :.: .:: ... NP_001 ASDALDKIRYESLTDPSKL-------------------DSG-----KELKIDIS------ 50 60 70 180 190 200 210 220 230 pF1KB9 SKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVF .:::::::::::..::..: : .. . : : :...: : NP_001 -----------------MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAGGSF 80 90 100 110 240 250 260 270 280 290 pF1KB9 EIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR---- . : . :::.:.::: : :. : ::..:: :.:.:...: :::. .: NP_001 TVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEI 120 130 140 150 160 170 pF1KB9 --------------------------------------------------------MNTL .: NP_001 SDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKT 180 190 200 210 220 230 300 310 320 330 340 350 pF1KB9 QAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDV . :: .: :. . .. :::. ... . . :..... :..:.....: : ::. NP_001 KPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP--FDL 240 250 260 270 280 290 360 370 380 390 400 410 pF1KB9 --SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRK ... ... :: :.:.:. . ...:..: ::::::::::.:::.:::.::.: ... NP_001 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 300 310 320 330 340 350 420 430 440 450 460 470 pF1KB9 LRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESS .: . .. ...: . .. : :.: ::.: .. .. :: .. .. ...::::..: NP_001 IRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRYHTS 360 370 380 390 400 410 480 490 500 510 520 530 pF1KB9 ALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFD :: ..::::::.:::. ..:::. . ... . .: . : ..:. ::.. : .: NP_001 --QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPID 420 430 440 450 460 470 540 550 560 570 580 590 pF1KB9 ELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGS : . .:.::: :.:.:: . . . :.. :... : :. . :.: :...: . NP_001 EYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEILDK 480 490 500 510 520 600 610 620 630 640 pF1KB9 RVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINPRHA .: .: .. :: . : ... .: ..... : : .. .. . ::::: : NP_001 KVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHP 530 540 550 560 570 580 650 660 670 680 690 700 pF1KB9 LIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALERH ... : : .. . .. :: ..:.:....:. ..::.. .:. ... NP_001 IVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED 590 600 610 620 630 640 NP_001 EVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 650 660 670 >>NP_001258901 (OMIM: 140572) heat shock protein HSP 90- (714 aa) initn: 869 init1: 289 opt: 628 Z-score: 673.4 bits: 135.1 E(85289): 9e-31 Smith-Waterman score: 1072; 30.7% identity (61.8% similar) in 684 aa overlap (90-697:17-674) 60 70 80 90 100 110 pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN :::: .:.... ..::.::.:.:::::: NP_001 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN 10 20 30 40 120 130 140 150 160 170 pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA :::::.:.:.. ..: . : :..: . : .. :.:. :::::::. .:..:::::: NP_001 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS .::.:::..::: ::::::::..::..: : .. . : : :... NP_001 KSGTKAFMEALQ------------FGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG 110 120 130 140 150 240 250 260 270 280 290 pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR- : : . : . :::.:.::: : :. : ::..:: :.:.:...: :::. .: NP_001 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 160 170 180 190 200 210 pF1KB9 -----------------------------------------------------------M . NP_001 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM : . :: .: :. . .. :::. ... . . :..... :..:.....: : NP_001 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP-- 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL ::. ... ... :: :.:.:. . ...:..: ::::::::::.:::.:::.::.: . NP_001 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY .. .: . .. ...: . .. : :.: ::.: .. .. :: .. .. ...:::: NP_001 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY 400 410 420 430 440 480 490 500 510 520 pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE ..: :: ..::::::.:::. ..:::. . ... . .: . : ..:. ::.. : NP_001 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE 450 460 470 480 490 500 530 540 550 560 570 580 pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV .:: . .:.::: :.:.:: . . . :.. :... : :. . :.: :... NP_001 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI 510 520 530 540 550 560 590 600 610 620 630 640 pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP : ..: .: .. :: . : ... .: ..... : : .. .. . ::::: NP_001 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP 570 580 590 600 610 620 650 660 670 680 690 700 pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER : ... : : .. . .. :: ..:.:....:. ..::.. .:. ... NP_001 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI 630 640 650 660 670 680 pF1KB9 H NP_001 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 690 700 710 >>NP_031381 (OMIM: 140572) heat shock protein HSP 90-bet (724 aa) initn: 895 init1: 289 opt: 628 Z-score: 673.3 bits: 135.1 E(85289): 9.1e-31 Smith-Waterman score: 1122; 31.4% identity (62.9% similar) in 684 aa overlap (90-697:17-684) 60 70 80 90 100 110 pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN :::: .:.... ..::.::.:.:::::: NP_031 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN 10 20 30 40 120 130 140 150 160 170 pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA :::::.:.:.. ..: . : :..: . : .. :.:. :::::::. .:..:::::: NP_031 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS .::.:::..::: :. : .:::::::::::..::..: : .. . : : :... NP_031 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR- : : . : . :::.:.::: : :. : ::..:: :.:.:...: :::. .: NP_031 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 170 180 190 200 210 220 pF1KB9 -----------------------------------------------------------M . NP_031 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM : . :: .: :. . .. :::. ... . . :..... :..:.....: : NP_031 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP-- 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL ::. ... ... :: :.:.:. . ...:..: ::::::::::.:::.:::.::.: . NP_031 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY .. .: . .. ...: . .. : :.: ::.: .. .. :: .. .. ...:::: NP_031 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY 410 420 430 440 450 480 490 500 510 520 pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE ..: :: ..::::::.:::. ..:::. . ... . .: . : ..:. ::.. : NP_031 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE 460 470 480 490 500 510 530 540 550 560 570 580 pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV .:: . .:.::: :.:.:: . . . :.. :... : :. . :.: :... NP_031 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP : ..: .: .. :: . : ... .: ..... : : .. .. . ::::: NP_031 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER : ... : : .. . .. :: ..:.:....:. ..::.. .:. ... NP_031 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI 640 650 660 670 680 690 pF1KB9 H NP_031 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 700 710 720 >>NP_001258899 (OMIM: 140572) heat shock protein HSP 90- (724 aa) initn: 895 init1: 289 opt: 628 Z-score: 673.3 bits: 135.1 E(85289): 9.1e-31 Smith-Waterman score: 1122; 31.4% identity (62.9% similar) in 684 aa overlap (90-697:17-684) 60 70 80 90 100 110 pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN :::: .:.... ..::.::.:.:::::: NP_001 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN 10 20 30 40 120 130 140 150 160 170 pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA :::::.:.:.. ..: . : :..: . : .. :.:. :::::::. .:..:::::: NP_001 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS .::.:::..::: :. : .:::::::::::..::..: : .. . : : :... NP_001 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR- : : . : . :::.:.::: : :. : ::..:: :.:.:...: :::. .: NP_001 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 170 180 190 200 210 220 pF1KB9 -----------------------------------------------------------M . NP_001 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM : . :: .: :. . .. :::. ... . . :..... :..:.....: : NP_001 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP-- 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL ::. ... ... :: :.:.:. . ...:..: ::::::::::.:::.:::.::.: . NP_001 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY .. .: . .. ...: . .. : :.: ::.: .. .. :: .. .. ...:::: NP_001 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY 410 420 430 440 450 480 490 500 510 520 pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE ..: :: ..::::::.:::. ..:::. . ... . .: . : ..:. ::.. : NP_001 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE 460 470 480 490 500 510 530 540 550 560 570 580 pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV .:: . .:.::: :.:.:: . . . :.. :... : :. . :.: :... NP_001 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP : ..: .: .. :: . : ... .: ..... : : .. .. . ::::: NP_001 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER : ... : : .. . .. :: ..:.:....:. ..::.. .:. ... NP_001 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI 640 650 660 670 680 690 pF1KB9 H NP_001 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 700 710 720 >>NP_001258898 (OMIM: 140572) heat shock protein HSP 90- (724 aa) initn: 895 init1: 289 opt: 628 Z-score: 673.3 bits: 135.1 E(85289): 9.1e-31 Smith-Waterman score: 1122; 31.4% identity (62.9% similar) in 684 aa overlap (90-697:17-684) 60 70 80 90 100 110 pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN :::: .:.... ..::.::.:.:::::: NP_001 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN 10 20 30 40 120 130 140 150 160 170 pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA :::::.:.:.. ..: . : :..: . : .. :.:. :::::::. .:..:::::: NP_001 ASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS .::.:::..::: :. : .:::::::::::..::..: : .. . : : :... NP_001 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVVVITKHNDDEQ--YAWESSAG 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFP--LYLNGRR- : : . : . :::.:.::: : :. : ::..:: :.:.:...: :::. .: NP_001 GSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 170 180 190 200 210 220 pF1KB9 -----------------------------------------------------------M . NP_001 KEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB9 NTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSM : . :: .: :. . .. :::. ... . . :..... :..:.....: : NP_001 NKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAP-- 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 FDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESAL ::. ... ... :: :.:.:. . ...:..: ::::::::::.:::.:::.::.: . NP_001 FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKI 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 IRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRY .. .: . .. ...: . .. : :.: ::.: .. .. :: .. .. ...:::: NP_001 LKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRY 410 420 430 440 450 480 490 500 510 520 pF1KB9 ESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFE ..: :: ..::::::.:::. ..:::. . ... . .: . : ..:. ::.. : NP_001 HTS--QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE 460 470 480 490 500 510 530 540 550 560 570 580 pF1KB9 QFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNV .:: . .:.::: :.:.:: . . . :.. :... : :. . :.: :... NP_001 PIDEYCVQQLKEFDGKSLVSVTKEGL--ELPEDE-EEKKKMEE--SKAKFENLCKLMKEI 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 LGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQPTLEINP : ..: .: .. :: . : ... .: ..... : : .. .. . ::::: NP_001 LDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINP 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 RHALIKKLNQLRASEPG--LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELLVKALER : ... : : .. . .. :: ..:.:....:. ..::.. .:. ... NP_001 DHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGI 640 650 660 670 680 690 pF1KB9 H NP_001 DEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 700 710 720 >>NP_005339 (OMIM: 140571) heat shock protein HSP 90-alp (732 aa) initn: 993 init1: 306 opt: 626 Z-score: 671.1 bits: 134.7 E(85289): 1.2e-30 Smith-Waterman score: 1113; 31.3% identity (62.9% similar) in 690 aa overlap (90-697:22-692) 60 70 80 90 100 110 pF1KB9 STQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN :::: .:.... ..::.::.:.:::::: NP_005 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN 10 20 30 40 50 120 130 140 150 160 170 pF1KB9 ASDALEKLRHKLVSDGQALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIA .::::.:.:.. ..: . : :..:.: : . :.:: :::::::. .:..:::::: NP_005 SSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIA 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB9 RSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGS .::.:::..::: :. : .:::::::::::..::..: : .. . : : :... NP_005 KSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVAEKVTVITKHNDDEQ--YAWESSAG 120 130 140 150 160 240 250 260 270 280 pF1KB9 GVFEIAEASG--VRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPL--------- : : . .: . :::.:.::: : :. : :....: :.:.:...:. NP_005 GSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERD 170 180 190 200 210 220 pF1KB9 --------------------------------------------------------YLNG :.. NP_005 KEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQ 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 RRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMK ...: . :: .: :. . .. :::. ... . . :..... :..:....:: NP_005 EELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRA 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 PSMFDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQE : ::. .:. ... :: :.:.:. . ...:..: ::::::::::.:::.:::.::. NP_005 P--FDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB9 SALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKL : ... .: : .. ...: . .. : :.: ::.:... .. :: ... .. ...: NP_005 SKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKLSEL 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB9 LRYESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLF ::: .:: :: ...::..: .::. . ..:::. . .. . .: . : ..:. ::.. NP_005 LRYYTSA--SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIY 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB9 CFEQFDELTLLHLREFDKKKLISVETD-IVVDHYKEEKFEDRSPAAECLSEKET--EELM .: .:: . .:.::. : :.:: . . . . .::: ... ::.: :.: NP_005 MIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQE--------EKKTKFENLC 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 AWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQP :...: ..: .: :. :: : : ... .: ..... : : .. . . NP_005 KIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKK 580 590 600 610 620 630 650 660 670 680 690 pF1KB9 TLEINPRHALIKKLNQLRASEPGLAQL--LVDQIYENAMIAAGL-VDDPRAMVGRLNELL ::::: :..:. : : .. . .. :: .::.:....:. ..::.. ..:. ... NP_005 HLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMI 640 650 660 670 680 690 700 pF1KB9 VKALERH NP_005 KLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 700 710 720 730 704 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:02:54 2016 done: Fri Nov 4 09:02:56 2016 Total Scan time: 10.590 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]