Result of FASTA (omim) for
pF1KB9973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9973, 554 aa
1>>>pF1KB9973 554 - 554 aa - 554 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.6534+/-0.000411; mu= -21.7123+/- 0.025
mean_var=423.2969+/-87.746, 0's: 0 Z-trim(122.4): 8 B-trim: 0 in 0/58
Lambda= 0.062338
statistics sampled from 40466 (40474) to 40466 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.475), width: 16
Scan time: 10.380
The best scores are: opt bits E(85289)
NP_757351 (OMIM: 120420) macrophage colony-stimula ( 554) 3783 354.6 4.9e-97
NP_000748 (OMIM: 120420) macrophage colony-stimula ( 554) 3783 354.6 4.9e-97
XP_016855858 (OMIM: 120420) PREDICTED: macrophage ( 513) 3495 328.6 2.9e-89
NP_757349 (OMIM: 120420) macrophage colony-stimula ( 438) 2493 238.5 3.3e-62
NP_757350 (OMIM: 120420) macrophage colony-stimula ( 256) 1215 123.4 8.4e-28
>>NP_757351 (OMIM: 120420) macrophage colony-stimulating (554 aa)
initn: 3783 init1: 3783 opt: 3783 Z-score: 1863.2 bits: 354.6 E(85289): 4.9e-97
Smith-Waterman score: 3783; 100.0% identity (100.0% similar) in 554 aa overlap (1-554:1-554)
10 20 30 40 50 60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
490 500 510 520 530 540
550
pF1KB9 SPLTQDDRQVELPV
::::::::::::::
NP_757 SPLTQDDRQVELPV
550
>>NP_000748 (OMIM: 120420) macrophage colony-stimulating (554 aa)
initn: 3783 init1: 3783 opt: 3783 Z-score: 1863.2 bits: 354.6 E(85289): 4.9e-97
Smith-Waterman score: 3783; 100.0% identity (100.0% similar) in 554 aa overlap (1-554:1-554)
10 20 30 40 50 60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
490 500 510 520 530 540
550
pF1KB9 SPLTQDDRQVELPV
::::::::::::::
NP_000 SPLTQDDRQVELPV
550
>>XP_016855858 (OMIM: 120420) PREDICTED: macrophage colo (513 aa)
initn: 3495 init1: 3495 opt: 3495 Z-score: 1723.7 bits: 328.6 E(85289): 2.9e-89
Smith-Waterman score: 3495; 99.8% identity (99.8% similar) in 513 aa overlap (42-554:1-513)
20 30 40 50 60 70
pF1KB9 PTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVD
::::::::::::::::::::::::::::::
XP_016 MIGSGHLQSLQRLIDSQMETSCQITFEFVD
10 20 30
80 90 100 110 120 130
pF1KB9 QEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHD
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB9 KACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNC
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB9 LYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQ
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB9 RPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGE
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB9 ASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVG
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB9 PVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSS
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB9 GSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 GSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSFSP
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB9 QLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVE
460 470 480 490 500 510
pF1KB9 LPV
:::
XP_016 LPV
>>NP_757349 (OMIM: 120420) macrophage colony-stimulating (438 aa)
initn: 2493 init1: 2493 opt: 2493 Z-score: 1237.7 bits: 238.5 E(85289): 3.3e-62
Smith-Waterman score: 2741; 79.1% identity (79.1% similar) in 554 aa overlap (1-554:1-438)
10 20 30 40 50 60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
::::
NP_757 DVTG--------------------------------------------------------
430 440 450 460 470 480
pF1KB9 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
NP_757 ------------------------------------------------------------
490 500 510 520 530 540
pF1KB9 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
370 380 390 400 410 420
550
pF1KB9 SPLTQDDRQVELPV
::::::::::::::
NP_757 SPLTQDDRQVELPV
430
>>NP_757350 (OMIM: 120420) macrophage colony-stimulating (256 aa)
initn: 1243 init1: 1215 opt: 1215 Z-score: 620.1 bits: 123.4 E(85289): 8.4e-28
Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
:
NP_757 QGHERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQP
190 200 210 220 230 240
>--
initn: 505 init1: 505 opt: 505 Z-score: 275.0 bits: 59.6 E(85289): 1.4e-08
Smith-Waterman score: 505; 100.0% identity (100.0% similar) in 75 aa overlap (480-554:182-256)
450 460 470 480 490 500
pF1KB9 RSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSSSPQLQESVFHLLVPSVILVL
::::::::::::::::::::::::::::::
NP_757 VFNETKNLLDKDWNIFSKNCNNSFAECSSQGHERQSEGSSSPQLQESVFHLLVPSVILVL
160 170 180 190 200 210
510 520 530 540 550
pF1KB9 LAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVELPV
:::::::::::::::::::::::::::::::::::::::::::::
NP_757 LAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVELPV
220 230 240 250
554 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:01:16 2016 done: Sat Nov 5 15:01:17 2016
Total Scan time: 10.380 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]