FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9977, 557 aa 1>>>pF1KB9977 557 - 557 aa - 557 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1708+/-0.000433; mu= 13.7542+/- 0.027 mean_var=89.5971+/-18.604, 0's: 0 Z-trim(110.3): 81 B-trim: 168 in 2/53 Lambda= 0.135496 statistics sampled from 18595 (18662) to 18595 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.219), width: 16 Scan time: 9.600 The best scores are: opt bits E(85289) NP_000620 (OMIM: 107450) interferon alpha/beta rec ( 557) 3694 733.1 5.6e-211 XP_005261021 (OMIM: 107450) PREDICTED: interferon ( 488) 3251 646.4 5.9e-185 XP_011527854 (OMIM: 107450) PREDICTED: interferon ( 270) 1763 355.4 1.3e-97 NP_000619 (OMIM: 123889,610424,612567) interleukin ( 325) 298 69.1 2.5e-11 NP_055247 (OMIM: 605620) interleukin-20 receptor s ( 553) 239 57.7 1.1e-07 NP_005525 (OMIM: 147569,614889) interferon gamma r ( 337) 232 56.2 2e-07 XP_016866443 (OMIM: 605620) PREDICTED: interleukin ( 554) 234 56.7 2.3e-07 XP_011527856 (OMIM: 147569,614889) PREDICTED: inte ( 339) 226 55.0 4.4e-07 NP_001316057 (OMIM: 147569,614889) interferon gamm ( 356) 226 55.0 4.6e-07 XP_011527855 (OMIM: 147569,614889) PREDICTED: inte ( 362) 226 55.0 4.7e-07 NP_851826 (OMIM: 606648) interleukin-22 receptor s ( 231) 200 49.8 1.1e-05 NP_001265651 (OMIM: 605620) interleukin-20 recepto ( 504) 204 50.8 1.2e-05 XP_016866444 (OMIM: 605620) PREDICTED: interleukin ( 505) 199 49.8 2.4e-05 NP_443194 (OMIM: 606648) interleukin-22 receptor s ( 263) 190 47.9 4.7e-05 NP_067081 (OMIM: 605457) interleukin-22 receptor s ( 574) 194 48.9 5.3e-05 NP_000407 (OMIM: 107470,209950,600263,607948,61042 ( 489) 158 41.8 0.006 NP_734464 (OMIM: 607404) interferon lambda recepto ( 520) 156 41.4 0.0083 >>NP_000620 (OMIM: 107450) interferon alpha/beta recepto (557 aa) initn: 3694 init1: 3694 opt: 3694 Z-score: 3908.7 bits: 733.1 E(85289): 5.6e-211 Smith-Waterman score: 3694; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557) 10 20 30 40 50 60 pF1KB9 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN 490 500 510 520 530 540 550 pF1KB9 EDESESKTSEELQQDFV ::::::::::::::::: NP_000 EDESESKTSEELQQDFV 550 >>XP_005261021 (OMIM: 107450) PREDICTED: interferon alph (488 aa) initn: 3251 init1: 3251 opt: 3251 Z-score: 3441.5 bits: 646.4 E(85289): 5.9e-185 Smith-Waterman score: 3251; 100.0% identity (100.0% similar) in 488 aa overlap (70-557:1-488) 40 50 60 70 80 90 pF1KB9 IIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEE :::::::::::::::::::::::::::::: XP_005 MDNWIKLSGCQNITSTKCNFSSLKLNVYEE 10 20 30 100 110 120 130 140 150 pF1KB9 IKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALD 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB9 GLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVH 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB9 CIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB9 IPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNI 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB9 RSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPL 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB9 TVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKV 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB9 FLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQ 400 410 420 430 440 450 520 530 540 550 pF1KB9 TDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV :::::::::::::::::::::::::::::::::::::: XP_005 TDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV 460 470 480 >>XP_011527854 (OMIM: 107450) PREDICTED: interferon alph (270 aa) initn: 1763 init1: 1763 opt: 1763 Z-score: 1873.4 bits: 355.4 E(85289): 1.3e-97 Smith-Waterman score: 1763; 98.5% identity (99.6% similar) in 268 aa overlap (1-268:1-268) 10 20 30 40 50 60 pF1KB9 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK ::::::::::::::::::::::: ...: XP_011 NQNYVLKWDYTYANMTFQVQWLHLYFRRPR 250 260 270 >>NP_000619 (OMIM: 123889,610424,612567) interleukin-10 (325 aa) initn: 218 init1: 121 opt: 298 Z-score: 324.4 bits: 69.1 E(85289): 2.5e-11 Smith-Waterman score: 357; 25.0% identity (60.2% similar) in 324 aa overlap (209-521:2-308) 180 190 200 210 220 230 pF1KB9 RIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVS .:..: . :. ... . .:::::.... NP_000 MAWSLGSWLG-GCLLVSALGMVPPPENVRMN 10 20 30 240 250 260 270 280 290 pF1KB9 VQNQNYVLKWD---YTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQ : . .:.:. .. .:.:: .:.: :. : : :. :.: : . NP_000 SVNFKNILQWESPAFAKGNLTFTAQYLS-----------YRIFQ-DKCMNTTLTECDF-S 40 50 60 70 300 310 320 330 340 350 pF1KB9 NVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQ .. . : . :::.: ... : : . : : .... :: .... :.::.:. . ::: NP_000 SLSKYGDHTLRVRAEFADEHSDWVN-ITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKI 80 90 100 110 120 130 360 370 380 390 400 410 pF1KB9 SGN--TPVIQDY--PLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTM .. : .... :.. .:.: .. . .: . .. ::.: :.:::..:. NP_000 ENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLP 140 150 160 170 180 190 420 430 440 450 460 470 pF1KB9 DEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIA-LFALPFVIYAAKVFLRCINYVFFP :. ::.. .:. :::.: .: :... : .: .: . ... . ..: :. NP_000 DR--NKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKY 200 210 220 230 240 250 480 490 500 510 520 pF1KB9 SLKPSSSIDEYFSE---QPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKY ...: .:. ....: .: .: :: : .. .....:.:: :... . NP_000 AFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCS 260 270 280 290 300 310 530 540 550 pF1KB9 SSQTSQDSGNYSNEDESESKTSEELQQDFV NP_000 LGTPPGQGPQS 320 >>NP_055247 (OMIM: 605620) interleukin-20 receptor subun (553 aa) initn: 173 init1: 89 opt: 239 Z-score: 258.6 bits: 57.7 E(85289): 1.1e-07 Smith-Waterman score: 249; 26.3% identity (57.5% similar) in 228 aa overlap (11-223:18-239) 10 20 30 40 50 pF1KB9 MMVVLLGATTLVLVAVAPW--VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNR :.:. .::: .. ..:: : .: .. :. . .:.:. NP_055 MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGG--LPKPANITFLSINMKNVLQWTP 10 20 30 40 50 60 70 80 90 100 pF1KB9 SDESVG-NVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRA-EKE . : .::.. .: :. .:.. : :.::. : :..:. . .. ...: NP_055 PEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGT 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 NTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAI-VIHISP-----GTKD---SVMWALDG . :.: : : :: ..::::::: : ...:.: :. .: . .: :.. .. NP_055 KCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSN 120 130 140 150 160 170 170 180 190 200 210 pF1KB9 LSFTYSLVIWKNSSGVEERIENIYSRHKIYK--LSPETTYCLKVKAALLTSWKIGVYSPV :... :.. :.. . . : : . : :.: ::..:.. . . . : NP_055 LKYNVSVLNTKSNRTWSQCVTN----HTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEK 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 HCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWK .: .: NP_055 QCARTLKDQSSEFKAKIIFWYVLPISITVFLFSVMGYSIYRYIHVGKEKHPANLILIYGN 240 250 260 270 280 290 >>NP_005525 (OMIM: 147569,614889) interferon gamma recep (337 aa) initn: 157 init1: 81 opt: 232 Z-score: 254.5 bits: 56.2 E(85289): 2e-07 Smith-Waterman score: 232; 22.0% identity (51.8% similar) in 328 aa overlap (212-521:13-332) 190 200 210 220 230 240 pF1KB9 NIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQN .::.. . ..:: :.. .. . : NP_005 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYN 10 20 30 40 250 260 270 280 290 pF1KB9 QNYVLKWD-YTYANMTFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQ . ::.:. . .: : : . : . .: .: .. .:.: : . NP_005 AEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPS 50 60 70 80 90 100 300 310 320 330 340 350 pF1KB9 KGIYL-----LRVQASDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAP :. . ::..: : : : :. .. . :: ... :. : ...: NP_005 AGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP 110 120 130 140 150 160 360 370 380 390 400 410 pF1KB9 KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDE . ..: . . : . .::. . . : ....... :::: :::....:. . NP_005 FDIADTSTAF---FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL-- 170 180 190 200 210 420 430 440 450 460 pF1KB9 KLNKSSVF-----SDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC----- :::..: :. : .: .... .. : .. :.: :. .: :: NP_005 -WNKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGL 220 230 240 250 260 270 470 480 490 500 510 520 pF1KB9 INYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDED :.: : . .:.::... : . .: . .... : . ...: : . : .: : NP_005 IKYWFHTPPSIPLQIEEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVL 280 290 300 310 320 330 530 540 550 pF1KB9 HKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV NP_005 QTL >>XP_016866443 (OMIM: 605620) PREDICTED: interleukin-20 (554 aa) initn: 173 init1: 89 opt: 234 Z-score: 253.3 bits: 56.7 E(85289): 2.3e-07 Smith-Waterman score: 244; 26.2% identity (57.6% similar) in 229 aa overlap (11-223:18-240) 10 20 30 40 50 pF1KB9 MMVVLLGATTLVLVAVAPW--VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNR :.:. .::: .. ..:: : .: .. :. . .:.:. XP_016 MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGG--LPKPANITFLSINMKNVLQWTP 10 20 30 40 50 60 70 80 90 100 pF1KB9 SDESVG-NVTFSFDY-QKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRA-EK . : .::.. .: . :. .:.. : :.::. : :..:. . .. ...: XP_016 PEGLQGVKVTYTVQYFIRYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWG 60 70 80 90 100 110 110 120 130 140 150 pF1KB9 ENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAI-VIHISP-----GTKD---SVMWALD . :.: : : :: ..::::::: : ...:.: :. .: . .: :.. . XP_016 TKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 GLSFTYSLVIWKNSSGVEERIENIYSRHKIYK--LSPETTYCLKVKAALLTSWKIGVYSP .:... :.. :.. . . : : . : :.: ::..:.. . . . : XP_016 NLKYNVSVLNTKSNRTWSQCVTN----HTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSE 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 VHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKW .: .: XP_016 KQCARTLKDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLILIYG 240 250 260 270 280 290 >>XP_011527856 (OMIM: 147569,614889) PREDICTED: interfer (339 aa) initn: 157 init1: 81 opt: 226 Z-score: 248.1 bits: 55.0 E(85289): 4.4e-07 Smith-Waterman score: 226; 22.4% identity (52.4% similar) in 313 aa overlap (227-521:30-334) 200 210 220 230 240 250 pF1KB9 TYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANM ..:: :.. .. . : . ::.:. . .: XP_011 MSTPSSSESVNLGMCCLTYKRDSADVNPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNS 10 20 30 40 50 260 270 280 290 300 pF1KB9 TFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQKGIYL-----LRVQA : : . : . .: .: .. .:.: : . :. . ::..: XP_011 TRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRA 60 70 80 90 100 110 310 320 330 340 350 360 pF1KB9 SDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLI : : : :. .. . :: ... :. : ...: . ..: . . XP_011 ELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FC 120 130 140 150 160 170 370 380 390 400 410 420 pF1KB9 YEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SD : . .::. . . : ....... :::: :::....:. . :::..: :. XP_011 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSN 180 190 200 210 220 230 430 440 450 460 470 pF1KB9 AVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----INYVFFPSLKPSSSI : .: .... .. : .. :.: :. .: :: :.: : . .: XP_011 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI 240 250 260 270 280 290 480 490 500 510 520 530 pF1KB9 DEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNY .::... : . .: . .... : . ...: : . : .: : XP_011 EEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVLQTL 300 310 320 330 540 550 pF1KB9 SNEDESESKTSEELQQDFV >>NP_001316057 (OMIM: 147569,614889) interferon gamma re (356 aa) initn: 157 init1: 81 opt: 226 Z-score: 247.8 bits: 55.0 E(85289): 4.6e-07 Smith-Waterman score: 226; 22.4% identity (52.4% similar) in 313 aa overlap (227-521:47-351) 200 210 220 230 240 250 pF1KB9 TYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANM ..:: :.. .. . : . ::.:. . .: NP_001 AAAAAAPPAQLTLETYQEWCNDSAATHDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNS 20 30 40 50 60 70 260 270 280 290 300 pF1KB9 TFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQKGIYL-----LRVQA : : . : . .: .: .. .:.: : . :. . ::..: NP_001 TRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRA 80 90 100 110 120 130 310 320 330 340 350 360 pF1KB9 SDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLI : : : :. .. . :: ... :. : ...: . ..: . . NP_001 ELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FC 140 150 160 170 180 190 370 380 390 400 410 420 pF1KB9 YEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SD : . .::. . . : ....... :::: :::....:. . :::..: :. NP_001 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSN 200 210 220 230 240 250 430 440 450 460 470 pF1KB9 AVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----INYVFFPSLKPSSSI : .: .... .. : .. :.: :. .: :: :.: : . .: NP_001 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI 260 270 280 290 300 310 480 490 500 510 520 530 pF1KB9 DEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNY .::... : . .: . .... : . ...: : . : .: : NP_001 EEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVLQTL 320 330 340 350 540 550 pF1KB9 SNEDESESKTSEELQQDFV >>XP_011527855 (OMIM: 147569,614889) PREDICTED: interfer (362 aa) initn: 157 init1: 81 opt: 226 Z-score: 247.7 bits: 55.0 E(85289): 4.7e-07 Smith-Waterman score: 226; 22.4% identity (52.4% similar) in 313 aa overlap (227-521:53-357) 200 210 220 230 240 250 pF1KB9 TYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANM ..:: :.. .. . : . ::.:. . .: XP_011 PKDVHALILRVREPGNVLPDVQKGLRRYPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNS 30 40 50 60 70 80 260 270 280 290 300 pF1KB9 TFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQKGIYL-----LRVQA : : . : . .: .: .. .:.: : . :. . ::..: XP_011 TRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRA 90 100 110 120 130 140 310 320 330 340 350 360 pF1KB9 SDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLI : : : :. .. . :: ... :. : ...: . ..: . . XP_011 ELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FC 150 160 170 180 190 370 380 390 400 410 420 pF1KB9 YEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SD : . .::. . . : ....... :::: :::....:. . :::..: :. XP_011 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSN 200 210 220 230 240 250 430 440 450 460 470 pF1KB9 AVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----INYVFFPSLKPSSSI : .: .... .. : .. :.: :. .: :: :.: : . .: XP_011 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI 260 270 280 290 300 310 480 490 500 510 520 530 pF1KB9 DEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNY .::... : . .: . .... : . ...: : . : .: : XP_011 EEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVLQTL 320 330 340 350 360 540 550 pF1KB9 SNEDESESKTSEELQQDFV 557 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:56:00 2016 done: Fri Nov 4 08:56:02 2016 Total Scan time: 9.600 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]