FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9977, 557 aa
1>>>pF1KB9977 557 - 557 aa - 557 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1708+/-0.000433; mu= 13.7542+/- 0.027
mean_var=89.5971+/-18.604, 0's: 0 Z-trim(110.3): 81 B-trim: 168 in 2/53
Lambda= 0.135496
statistics sampled from 18595 (18662) to 18595 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.219), width: 16
Scan time: 9.600
The best scores are: opt bits E(85289)
NP_000620 (OMIM: 107450) interferon alpha/beta rec ( 557) 3694 733.1 5.6e-211
XP_005261021 (OMIM: 107450) PREDICTED: interferon ( 488) 3251 646.4 5.9e-185
XP_011527854 (OMIM: 107450) PREDICTED: interferon ( 270) 1763 355.4 1.3e-97
NP_000619 (OMIM: 123889,610424,612567) interleukin ( 325) 298 69.1 2.5e-11
NP_055247 (OMIM: 605620) interleukin-20 receptor s ( 553) 239 57.7 1.1e-07
NP_005525 (OMIM: 147569,614889) interferon gamma r ( 337) 232 56.2 2e-07
XP_016866443 (OMIM: 605620) PREDICTED: interleukin ( 554) 234 56.7 2.3e-07
XP_011527856 (OMIM: 147569,614889) PREDICTED: inte ( 339) 226 55.0 4.4e-07
NP_001316057 (OMIM: 147569,614889) interferon gamm ( 356) 226 55.0 4.6e-07
XP_011527855 (OMIM: 147569,614889) PREDICTED: inte ( 362) 226 55.0 4.7e-07
NP_851826 (OMIM: 606648) interleukin-22 receptor s ( 231) 200 49.8 1.1e-05
NP_001265651 (OMIM: 605620) interleukin-20 recepto ( 504) 204 50.8 1.2e-05
XP_016866444 (OMIM: 605620) PREDICTED: interleukin ( 505) 199 49.8 2.4e-05
NP_443194 (OMIM: 606648) interleukin-22 receptor s ( 263) 190 47.9 4.7e-05
NP_067081 (OMIM: 605457) interleukin-22 receptor s ( 574) 194 48.9 5.3e-05
NP_000407 (OMIM: 107470,209950,600263,607948,61042 ( 489) 158 41.8 0.006
NP_734464 (OMIM: 607404) interferon lambda recepto ( 520) 156 41.4 0.0083
>>NP_000620 (OMIM: 107450) interferon alpha/beta recepto (557 aa)
initn: 3694 init1: 3694 opt: 3694 Z-score: 3908.7 bits: 733.1 E(85289): 5.6e-211
Smith-Waterman score: 3694; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KB9 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN
490 500 510 520 530 540
550
pF1KB9 EDESESKTSEELQQDFV
:::::::::::::::::
NP_000 EDESESKTSEELQQDFV
550
>>XP_005261021 (OMIM: 107450) PREDICTED: interferon alph (488 aa)
initn: 3251 init1: 3251 opt: 3251 Z-score: 3441.5 bits: 646.4 E(85289): 5.9e-185
Smith-Waterman score: 3251; 100.0% identity (100.0% similar) in 488 aa overlap (70-557:1-488)
40 50 60 70 80 90
pF1KB9 IIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEE
::::::::::::::::::::::::::::::
XP_005 MDNWIKLSGCQNITSTKCNFSSLKLNVYEE
10 20 30
100 110 120 130 140 150
pF1KB9 IKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB9 GLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB9 CIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQ
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB9 IPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNI
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB9 RSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB9 TVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKV
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB9 FLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQ
400 410 420 430 440 450
520 530 540 550
pF1KB9 TDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
::::::::::::::::::::::::::::::::::::::
XP_005 TDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
460 470 480
>>XP_011527854 (OMIM: 107450) PREDICTED: interferon alph (270 aa)
initn: 1763 init1: 1763 opt: 1763 Z-score: 1873.4 bits: 355.4 E(85289): 1.3e-97
Smith-Waterman score: 1763; 98.5% identity (99.6% similar) in 268 aa overlap (1-268:1-268)
10 20 30 40 50 60
pF1KB9 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK
::::::::::::::::::::::: ...:
XP_011 NQNYVLKWDYTYANMTFQVQWLHLYFRRPR
250 260 270
>>NP_000619 (OMIM: 123889,610424,612567) interleukin-10 (325 aa)
initn: 218 init1: 121 opt: 298 Z-score: 324.4 bits: 69.1 E(85289): 2.5e-11
Smith-Waterman score: 357; 25.0% identity (60.2% similar) in 324 aa overlap (209-521:2-308)
180 190 200 210 220 230
pF1KB9 RIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVS
.:..: . :. ... . .:::::....
NP_000 MAWSLGSWLG-GCLLVSALGMVPPPENVRMN
10 20 30
240 250 260 270 280 290
pF1KB9 VQNQNYVLKWD---YTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQ
: . .:.:. .. .:.:: .:.: :. : : :. :.: : .
NP_000 SVNFKNILQWESPAFAKGNLTFTAQYLS-----------YRIFQ-DKCMNTTLTECDF-S
40 50 60 70
300 310 320 330 340 350
pF1KB9 NVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQ
.. . : . :::.: ... : : . : : .... :: .... :.::.:. . :::
NP_000 SLSKYGDHTLRVRAEFADEHSDWVN-ITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKI
80 90 100 110 120 130
360 370 380 390 400 410
pF1KB9 SGN--TPVIQDY--PLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTM
.. : .... :.. .:.: .. . .: . .. ::.: :.:::..:.
NP_000 ENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLP
140 150 160 170 180 190
420 430 440 450 460 470
pF1KB9 DEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIA-LFALPFVIYAAKVFLRCINYVFFP
:. ::.. .:. :::.: .: :... : .: .: . ... . ..: :.
NP_000 DR--NKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKY
200 210 220 230 240 250
480 490 500 510 520
pF1KB9 SLKPSSSIDEYFSE---QPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKY
...: .:. ....: .: .: :: : .. .....:.:: :... .
NP_000 AFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCS
260 270 280 290 300 310
530 540 550
pF1KB9 SSQTSQDSGNYSNEDESESKTSEELQQDFV
NP_000 LGTPPGQGPQS
320
>>NP_055247 (OMIM: 605620) interleukin-20 receptor subun (553 aa)
initn: 173 init1: 89 opt: 239 Z-score: 258.6 bits: 57.7 E(85289): 1.1e-07
Smith-Waterman score: 249; 26.3% identity (57.5% similar) in 228 aa overlap (11-223:18-239)
10 20 30 40 50
pF1KB9 MMVVLLGATTLVLVAVAPW--VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNR
:.:. .::: .. ..:: : .: .. :. . .:.:.
NP_055 MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGG--LPKPANITFLSINMKNVLQWTP
10 20 30 40 50
60 70 80 90 100
pF1KB9 SDESVG-NVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRA-EKE
. : .::.. .: :. .:.. : :.::. : :..:. . .. ...:
NP_055 PEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGT
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 NTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAI-VIHISP-----GTKD---SVMWALDG
. :.: : : :: ..::::::: : ...:.: :. .: . .: :.. ..
NP_055 KCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSN
120 130 140 150 160 170
170 180 190 200 210
pF1KB9 LSFTYSLVIWKNSSGVEERIENIYSRHKIYK--LSPETTYCLKVKAALLTSWKIGVYSPV
:... :.. :.. . . : : . : :.: ::..:.. . . . :
NP_055 LKYNVSVLNTKSNRTWSQCVTN----HTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB9 HCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWK
.: .:
NP_055 QCARTLKDQSSEFKAKIIFWYVLPISITVFLFSVMGYSIYRYIHVGKEKHPANLILIYGN
240 250 260 270 280 290
>>NP_005525 (OMIM: 147569,614889) interferon gamma recep (337 aa)
initn: 157 init1: 81 opt: 232 Z-score: 254.5 bits: 56.2 E(85289): 2e-07
Smith-Waterman score: 232; 22.0% identity (51.8% similar) in 328 aa overlap (212-521:13-332)
190 200 210 220 230 240
pF1KB9 NIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQN
.::.. . ..:: :.. .. . :
NP_005 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYN
10 20 30 40
250 260 270 280 290
pF1KB9 QNYVLKWD-YTYANMTFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQ
. ::.:. . .: : : . : . .: .: .. .:.: : .
NP_005 AEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPS
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB9 KGIYL-----LRVQASDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAP
:. . ::..: : : : :. .. . :: ... :. : ...:
NP_005 AGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP
110 120 130 140 150 160
360 370 380 390 400 410
pF1KB9 KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDE
. ..: . . : . .::. . . : ....... :::: :::....:. .
NP_005 FDIADTSTAF---FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL--
170 180 190 200 210
420 430 440 450 460
pF1KB9 KLNKSSVF-----SDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----
:::..: :. : .: .... .. : .. :.: :. .: ::
NP_005 -WNKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGL
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB9 INYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDED
:.: : . .:.::... : . .: . .... : . ...: : . : .: :
NP_005 IKYWFHTPPSIPLQIEEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVL
280 290 300 310 320 330
530 540 550
pF1KB9 HKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
NP_005 QTL
>>XP_016866443 (OMIM: 605620) PREDICTED: interleukin-20 (554 aa)
initn: 173 init1: 89 opt: 234 Z-score: 253.3 bits: 56.7 E(85289): 2.3e-07
Smith-Waterman score: 244; 26.2% identity (57.6% similar) in 229 aa overlap (11-223:18-240)
10 20 30 40 50
pF1KB9 MMVVLLGATTLVLVAVAPW--VLSAAAGGKNLKSPQKVEVDIIDDNFILRWNR
:.:. .::: .. ..:: : .: .. :. . .:.:.
XP_016 MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGG--LPKPANITFLSINMKNVLQWTP
10 20 30 40 50
60 70 80 90 100
pF1KB9 SDESVG-NVTFSFDY-QKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRA-EK
. : .::.. .: . :. .:.. : :.::. : :..:. . .. ...:
XP_016 PEGLQGVKVTYTVQYFIRYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWG
60 70 80 90 100 110
110 120 130 140 150
pF1KB9 ENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAI-VIHISP-----GTKD---SVMWALD
. :.: : : :: ..::::::: : ...:.: :. .: . .: :.. .
XP_016 TKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 GLSFTYSLVIWKNSSGVEERIENIYSRHKIYK--LSPETTYCLKVKAALLTSWKIGVYSP
.:... :.. :.. . . : : . : :.: ::..:.. . . . :
XP_016 NLKYNVSVLNTKSNRTWSQCVTN----HTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSE
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB9 VHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKW
.: .:
XP_016 KQCARTLKDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLILIYG
240 250 260 270 280 290
>>XP_011527856 (OMIM: 147569,614889) PREDICTED: interfer (339 aa)
initn: 157 init1: 81 opt: 226 Z-score: 248.1 bits: 55.0 E(85289): 4.4e-07
Smith-Waterman score: 226; 22.4% identity (52.4% similar) in 313 aa overlap (227-521:30-334)
200 210 220 230 240 250
pF1KB9 TYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANM
..:: :.. .. . : . ::.:. . .:
XP_011 MSTPSSSESVNLGMCCLTYKRDSADVNPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNS
10 20 30 40 50
260 270 280 290 300
pF1KB9 TFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQKGIYL-----LRVQA
: : . : . .: .: .. .:.: : . :. . ::..:
XP_011 TRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRA
60 70 80 90 100 110
310 320 330 340 350 360
pF1KB9 SDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLI
: : : :. .. . :: ... :. : ...: . ..: . .
XP_011 ELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FC
120 130 140 150 160 170
370 380 390 400 410 420
pF1KB9 YEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SD
: . .::. . . : ....... :::: :::....:. . :::..: :.
XP_011 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSN
180 190 200 210 220 230
430 440 450 460 470
pF1KB9 AVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----INYVFFPSLKPSSSI
: .: .... .. : .. :.: :. .: :: :.: : . .:
XP_011 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI
240 250 260 270 280 290
480 490 500 510 520 530
pF1KB9 DEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNY
.::... : . .: . .... : . ...: : . : .: :
XP_011 EEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVLQTL
300 310 320 330
540 550
pF1KB9 SNEDESESKTSEELQQDFV
>>NP_001316057 (OMIM: 147569,614889) interferon gamma re (356 aa)
initn: 157 init1: 81 opt: 226 Z-score: 247.8 bits: 55.0 E(85289): 4.6e-07
Smith-Waterman score: 226; 22.4% identity (52.4% similar) in 313 aa overlap (227-521:47-351)
200 210 220 230 240 250
pF1KB9 TYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANM
..:: :.. .. . : . ::.:. . .:
NP_001 AAAAAAPPAQLTLETYQEWCNDSAATHDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNS
20 30 40 50 60 70
260 270 280 290 300
pF1KB9 TFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQKGIYL-----LRVQA
: : . : . .: .: .. .:.: : . :. . ::..:
NP_001 TRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRA
80 90 100 110 120 130
310 320 330 340 350 360
pF1KB9 SDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLI
: : : :. .. . :: ... :. : ...: . ..: . .
NP_001 ELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FC
140 150 160 170 180 190
370 380 390 400 410 420
pF1KB9 YEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SD
: . .::. . . : ....... :::: :::....:. . :::..: :.
NP_001 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSN
200 210 220 230 240 250
430 440 450 460 470
pF1KB9 AVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----INYVFFPSLKPSSSI
: .: .... .. : .. :.: :. .: :: :.: : . .:
NP_001 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI
260 270 280 290 300 310
480 490 500 510 520 530
pF1KB9 DEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNY
.::... : . .: . .... : . ...: : . : .: :
NP_001 EEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVLQTL
320 330 340 350
540 550
pF1KB9 SNEDESESKTSEELQQDFV
>>XP_011527855 (OMIM: 147569,614889) PREDICTED: interfer (362 aa)
initn: 157 init1: 81 opt: 226 Z-score: 247.7 bits: 55.0 E(85289): 4.7e-07
Smith-Waterman score: 226; 22.4% identity (52.4% similar) in 313 aa overlap (227-521:53-357)
200 210 220 230 240 250
pF1KB9 TYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD-YTYANM
..:: :.. .. . : . ::.:. . .:
XP_011 PKDVHALILRVREPGNVLPDVQKGLRRYPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNS
30 40 50 60 70 80
260 270 280 290 300
pF1KB9 TFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVFPQNVFQKGIYL-----LRVQA
: : . : . .: .: .. .:.: : . :. . ::..:
XP_011 TRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRA
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB9 SDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLI
: : : :. .. . :: ... :. : ...: . ..: . .
XP_011 ELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF---FC
150 160 170 180 190
370 380 390 400 410 420
pF1KB9 YEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVF-----SD
: . .::. . . : ....... :::: :::....:. . :::..: :.
XP_011 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL---WNKSNIFRVGHLSN
200 210 220 230 240 250
430 440 450 460 470
pF1KB9 AVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----INYVFFPSLKPSSSI
: .: .... .. : .. :.: :. .: :: :.: : . .:
XP_011 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI
260 270 280 290 300 310
480 490 500 510 520 530
pF1KB9 DEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNY
.::... : . .: . .... : . ...: : . : .: :
XP_011 EEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVLQTL
320 330 340 350 360
540 550
pF1KB9 SNEDESESKTSEELQQDFV
557 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:56:00 2016 done: Fri Nov 4 08:56:02 2016
Total Scan time: 9.600 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]