Result of FASTA (omim) for pF1KB9981
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9981, 561 aa
  1>>>pF1KB9981 561 - 561 aa - 561 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.4495+/-0.000427; mu= -22.3175+/- 0.027
 mean_var=613.2024+/-127.483, 0's: 0 Z-trim(125.6): 93  B-trim: 63 in 1/59
 Lambda= 0.051793
 statistics sampled from 49635 (49743) to 49635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.583), width:  16
 Scan time: 13.320

The best scores are:                                      opt bits E(85289)
NP_005855 (OMIM: 609906) embryonal Fyn-associated  ( 561) 3901 306.2 1.8e-82
NP_115835 (OMIM: 609906) embryonal Fyn-associated  ( 468) 3218 255.1 3.6e-67
XP_005267313 (OMIM: 609906) PREDICTED: embryonal F ( 531) 2778 222.3 3.1e-57
NP_001264103 (OMIM: 609906) embryonal Fyn-associat ( 392) 2090 170.7 7.5e-42
NP_001164192 (OMIM: 602941) breast cancer anti-est ( 660)  465 49.5 3.9e-05
NP_001164191 (OMIM: 602941) breast cancer anti-est ( 722)  465 49.5 4.2e-05
XP_016879388 (OMIM: 602941) PREDICTED: breast canc ( 823)  465 49.6 4.6e-05
XP_011521777 (OMIM: 602941) PREDICTED: breast canc ( 841)  465 49.6 4.7e-05
XP_005256317 (OMIM: 602941) PREDICTED: breast canc ( 841)  465 49.6 4.7e-05
NP_001164190 (OMIM: 602941) breast cancer anti-est ( 868)  465 49.6 4.8e-05
XP_005256316 (OMIM: 602941) PREDICTED: breast canc ( 870)  465 49.6 4.8e-05
NP_001164189 (OMIM: 602941) breast cancer anti-est ( 870)  465 49.6 4.8e-05
NP_055382 (OMIM: 602941) breast cancer anti-estrog ( 870)  465 49.6 4.8e-05
NP_001164187 (OMIM: 602941) breast cancer anti-est ( 888)  465 49.6 4.9e-05
NP_001164188 (OMIM: 602941) breast cancer anti-est ( 888)  465 49.6 4.9e-05
NP_001164186 (OMIM: 602941) breast cancer anti-est ( 888)  465 49.6 4.9e-05
XP_005256315 (OMIM: 602941) PREDICTED: breast canc ( 896)  465 49.6 4.9e-05
NP_001164185 (OMIM: 602941) breast cancer anti-est ( 916)  465 49.6   5e-05
XP_016879386 (OMIM: 602941) PREDICTED: breast canc ( 916)  465 49.6   5e-05
XP_016879387 (OMIM: 602941) PREDICTED: breast canc ( 886)  437 47.5 0.00021
NP_001257962 (OMIM: 602265) enhancer of filamentat ( 685)  383 43.4  0.0028
NP_006394 (OMIM: 602265) enhancer of filamentation ( 834)  383 43.5  0.0033
NP_001135865 (OMIM: 602265) enhancer of filamentat ( 834)  383 43.5  0.0033


>>NP_005855 (OMIM: 609906) embryonal Fyn-associated subs  (561 aa)
 initn: 3901 init1: 3901 opt: 3901  Z-score: 1601.6  bits: 306.2 E(85289): 1.8e-82
Smith-Waterman score: 3901; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561)

               10        20        30        40        50        60
pF1KB9 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEAL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ
              490       500       510       520       530       540

              550       560 
pF1KB9 CVTELAGQALQFTTLLTSLAP
       :::::::::::::::::::::
NP_005 CVTELAGQALQFTTLLTSLAP
              550       560 

>>NP_115835 (OMIM: 609906) embryonal Fyn-associated subs  (468 aa)
 initn: 3218 init1: 3218 opt: 3218  Z-score: 1326.9  bits: 255.1 E(85289): 3.6e-67
Smith-Waterman score: 3218; 100.0% identity (100.0% similar) in 462 aa overlap (100-561:7-468)

      70        80        90       100       110       120         
pF1KB9 PAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYK
                                     ::::::::::::::::::::::::::::::
NP_115                         MAIATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYK
                                       10        20        30      

     130       140       150       160       170       180         
pF1KB9 IPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 IPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYD
         40        50        60        70        80        90      

     190       200       210       220       230       240         
pF1KB9 VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTD
        100       110       120       130       140       150      

     250       260       270       280       290       300         
pF1KB9 EGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPA
        160       170       180       190       200       210      

     310       320       330       340       350       360         
pF1KB9 LPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHH
        220       230       240       250       260       270      

     370       380       390       400       410       420         
pF1KB9 NEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVS
        280       290       300       310       320       330      

     430       440       450       460       470       480         
pF1KB9 TGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGD
        340       350       360       370       380       390      

     490       500       510       520       530       540         
pF1KB9 TLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQA
        400       410       420       430       440       450      

     550       560 
pF1KB9 LQFTTLLTSLAP
       ::::::::::::
NP_115 LQFTTLLTSLAP
        460        

>>XP_005267313 (OMIM: 609906) PREDICTED: embryonal Fyn-a  (531 aa)
 initn: 2769 init1: 2769 opt: 2778  Z-score: 1148.4  bits: 222.3 E(85289): 3.1e-57
Smith-Waterman score: 3605; 94.7% identity (94.7% similar) in 561 aa overlap (1-561:1-531)

               10        20        30        40        50        60
pF1KB9 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEAL
       :::::::::::::::::::::::::::                              :::
XP_005 MEDDPAGHHNEYEGIPMAEEYDYVHLK------------------------------EAL
              370       380                                     390

              430       440       450       460       470       480
pF1KB9 SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVA
              400       410       420       430       440       450

              490       500       510       520       530       540
pF1KB9 AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQ
              460       470       480       490       500       510

              550       560 
pF1KB9 CVTELAGQALQFTTLLTSLAP
       :::::::::::::::::::::
XP_005 CVTELAGQALQFTTLLTSLAP
              520       530 

>>NP_001264103 (OMIM: 609906) embryonal Fyn-associated s  (392 aa)
 initn: 2115 init1: 2056 opt: 2090  Z-score: 872.4  bits: 170.7 E(85289): 7.5e-42
Smith-Waterman score: 2526; 83.5% identity (83.5% similar) in 462 aa overlap (100-561:7-392)

      70        80        90       100       110       120         
pF1KB9 PAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYK
                                     ::::::::::::::::::::::::::::::
NP_001                         MAIATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYK
                                       10        20        30      

     130       140       150       160       170       180         
pF1KB9 IPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
NP_001 IPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAP--
         40        50        60        70        80        90      

     190       200       210       220       230       240         
pF1KB9 VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTD
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

     250       260       270       280       290       300         
pF1KB9 EGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPA
                     ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------PSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPA
                        100       110       120       130       140

     310       320       330       340       350       360         
pF1KB9 LPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHH
              150       160       170       180       190       200

     370       380       390       400       410       420         
pF1KB9 NEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVS
              210       220       230       240       250       260

     430       440       450       460       470       480         
pF1KB9 TGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGD
              270       280       290       300       310       320

     490       500       510       520       530       540         
pF1KB9 TLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQA
              330       340       350       360       370       380

     550       560 
pF1KB9 LQFTTLLTSLAP
       ::::::::::::
NP_001 LQFTTLLTSLAP
              390  

>>NP_001164192 (OMIM: 602941) breast cancer anti-estroge  (660 aa)
 initn: 529 init1: 390 opt: 465  Z-score: 213.1  bits: 49.5 E(85289): 3.9e-05
Smith-Waterman score: 551; 30.5% identity (51.8% similar) in 587 aa overlap (58-560:98-658)

        30        40        50        60        70               80
pF1KB9 RGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPK-------PSLSPAS
                                     :: .  : .: ::  .       :... :.
NP_001 NGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAK
        70        80        90       100       110       120       

                    90       100       110       120       130     
pF1KB9 PAQPG-SPY----PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASG
       : .:. .:     : :: :   ..:: ::::: :   . :: :   :.:  .: .::   
NP_001 PFDPARTPLVLAAPPPD-SPPAEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPRERV
       130       140        150        160        170       180    

          140         150        160            170       180      
pF1KB9 TQ-LAAPRDALE--VYDVPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDA
           .:   ...  :: ::: : : .:. :     .:      :.  . .    ::..  
NP_001 LPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--
          190       200       210       220       230       240    

        190       200                      210       220       230 
pF1KB9 PYDVPLTPKPPAELEP----------DLEWEGG-----REPGPPIYAAPSNLKRASALLN
       : .. .. .  :.:.           ::   .:     : :. :     ..:. : : ..
NP_001 PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ
            250       260       270       280       290       300  

             240        250          260       270                 
pF1KB9 LYEAPEELLADGEGG-GTDEGIYDVPL---LGPEAPPSPEPPGALASHDQ----------
          : .:::  .... :.     :  :   :. .     .   .:..: :          
NP_001 --SAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSG
              310       320       330       340       350       360

          280       290             300       310       320        
pF1KB9 ---DTLAQLLARSPPPPHRPR-LPS-----AESLSRRPLPALPVPEAPSPSPVPSPAPGR
          . : .:.: :   :.  . : :     :  : ::   . : ::. . .  :.:.  .
NP_001 ATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGG-TLHPNPTD-K
              370       380       390       400        410         

      330       340       350       360       370       380        
pF1KB9 KGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG
        .:::.:::: ::                    .:.: :.... ::  : :.::::::.:
NP_001 TSSIQSRPLPSPPKFTS----------------QDSPDGQYENSEGGWM-EDYDYVHLQG
      420       430                       440       450        460 

         390       400                410                    420   
pF1KB9 ---MDKAQGSRPPDQACT--GDPELP-------ER-----GMP--------APQEALSPG
          ..:.:       . :  :  .:        ::     . :        .: . :.::
NP_001 KEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPG
             470       480       490       500       510       520 

           430       440       450       460       470       480   
pF1KB9 EPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHR
       .   .. .: ::: ::  ::... ..:  :: :..... .::::..:: ::: :...::.
NP_001 RTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHK
             530       540       550       560       570       580 

           490       500       510       520       530       540   
pF1KB9 LVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVT
       :::.::::.: : .: .:.::   .. : . ::. : ..:.::: :::  : :.::. : 
NP_001 LVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVK
             590       600       610       620       630       640 

           550       560  
pF1KB9 ELAGQALQFTTLLTSLAP 
       ::. .. ::  .: .::  
NP_001 ELGHSTQQFRRVLGQLAAA
             650       660

>>NP_001164191 (OMIM: 602941) breast cancer anti-estroge  (722 aa)
 initn: 668 init1: 390 opt: 465  Z-score: 212.6  bits: 49.5 E(85289): 4.2e-05
Smith-Waterman score: 551; 30.5% identity (51.8% similar) in 587 aa overlap (58-560:160-720)

        30        40        50        60        70               80
pF1KB9 RGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPK-------PSLSPAS
                                     :: .  : .: ::  .       :... :.
NP_001 NGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAK
     130       140       150       160       170       180         

                    90       100       110       120       130     
pF1KB9 PAQPG-SPY----PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASG
       : .:. .:     : :: :   ..:: ::::: :   . :: :   :.:  .: .::   
NP_001 PFDPARTPLVLAAPPPD-SPPAEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPRERV
     190       200        210       220         230       240      

          140         150        160            170       180      
pF1KB9 TQ-LAAPRDALE--VYDVPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDA
           .:   ...  :: ::: : : .:. :     .:      :.  . .    ::..  
NP_001 LPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--
        250       260       270       280       290       300      

        190       200                      210       220       230 
pF1KB9 PYDVPLTPKPPAELEP----------DLEWEGG-----REPGPPIYAAPSNLKRASALLN
       : .. .. .  :.:.           ::   .:     : :. :     ..:. : : ..
NP_001 PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ
          310       320       330       340       350       360    

             240        250          260       270                 
pF1KB9 LYEAPEELLADGEGG-GTDEGIYDVPL---LGPEAPPSPEPPGALASHDQ----------
          : .:::  .... :.     :  :   :. .     .   .:..: :          
NP_001 --SAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSG
            370       380       390       400       410       420  

          280       290             300       310       320        
pF1KB9 ---DTLAQLLARSPPPPHRPR-LPS-----AESLSRRPLPALPVPEAPSPSPVPSPAPGR
          . : .:.: :   :.  . : :     :  : ::   . : ::. . .  :.:.  .
NP_001 ATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGG-TLHPNPTD-K
            430       440       450       460       470         480

      330       340       350       360       370       380        
pF1KB9 KGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG
        .:::.:::: ::                    .:.: :.... ::  : :.::::::.:
NP_001 TSSIQSRPLPSPPKFTS----------------QDSPDGQYENSEGGWM-EDYDYVHLQG
              490                       500       510        520   

         390       400                410                    420   
pF1KB9 ---MDKAQGSRPPDQACT--GDPELP-------ER-----GMP--------APQEALSPG
          ..:.:       . :  :  .:        ::     . :        .: . :.::
NP_001 KEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPG
           530       540       550       560       570       580   

           430       440       450       460       470       480   
pF1KB9 EPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHR
       .   .. .: ::: ::  ::... ..:  :: :..... .::::..:: ::: :...::.
NP_001 RTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHK
           590       600       610       620       630       640   

           490       500       510       520       530       540   
pF1KB9 LVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVT
       :::.::::.: : .: .:.::   .. : . ::. : ..:.::: :::  : :.::. : 
NP_001 LVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVK
           650       660       670       680       690       700   

           550       560  
pF1KB9 ELAGQALQFTTLLTSLAP 
       ::. .. ::  .: .::  
NP_001 ELGHSTQQFRRVLGQLAAA
           710       720  

>>XP_016879388 (OMIM: 602941) PREDICTED: breast cancer a  (823 aa)
 initn: 650 init1: 390 opt: 465  Z-score: 211.8  bits: 49.6 E(85289): 4.6e-05
Smith-Waterman score: 551; 30.5% identity (51.8% similar) in 587 aa overlap (58-560:261-821)

        30        40        50        60        70               80
pF1KB9 RGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPK-------PSLSPAS
                                     :: .  : .: ::  .       :... :.
XP_016 AGMGHDIYQVPPSMDTRSWEGTKPPAKVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAK
              240       250       260       270       280       290

                    90       100       110       120       130     
pF1KB9 PAQPG-SPY----PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASG
       : .:. .:     : :: :   ..:: ::::: :   . :: :   :.:  .: .::   
XP_016 PFDPARTPLVLAAPPPD-SPPAEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPRERV
              300        310       320         330       340       

          140         150        160            170       180      
pF1KB9 TQ-LAAPRDALE--VYDVPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDA
           .:   ...  :: ::: : : .:. :     .:      :.  . .    ::..  
XP_016 LPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--
       350       360       370       380       390       400       

        190       200                      210       220       230 
pF1KB9 PYDVPLTPKPPAELEP----------DLEWEGG-----REPGPPIYAAPSNLKRASALLN
       : .. .. .  :.:.           ::   .:     : :. :     ..:. : : ..
XP_016 PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ
         410       420       430       440       450       460     

             240        250          260       270                 
pF1KB9 LYEAPEELLADGEGG-GTDEGIYDVPL---LGPEAPPSPEPPGALASHDQ----------
          : .:::  .... :.     :  :   :. .     .   .:..: :          
XP_016 --SAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSG
           470       480       490       500       510       520   

          280       290             300       310       320        
pF1KB9 ---DTLAQLLARSPPPPHRPR-LPS-----AESLSRRPLPALPVPEAPSPSPVPSPAPGR
          . : .:.: :   :.  . : :     :  : ::   . : ::. . .  :.:.  .
XP_016 ATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGG-TLHPNPTD-K
           530       540       550       560       570        580  

      330       340       350       360       370       380        
pF1KB9 KGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG
        .:::.:::: ::                    .:.: :.... ::  : :.::::::.:
XP_016 TSSIQSRPLPSPPKFTS----------------QDSPDGQYENSEGGWM-EDYDYVHLQG
             590                       600       610        620    

         390       400                410                    420   
pF1KB9 ---MDKAQGSRPPDQACT--GDPELP-------ER-----GMP--------APQEALSPG
          ..:.:       . :  :  .:        ::     . :        .: . :.::
XP_016 KEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPG
          630       640       650       660       670       680    

           430       440       450       460       470       480   
pF1KB9 EPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHR
       .   .. .: ::: ::  ::... ..:  :: :..... .::::..:: ::: :...::.
XP_016 RTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHK
          690       700       710       720       730       740    

           490       500       510       520       530       540   
pF1KB9 LVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVT
       :::.::::.: : .: .:.::   .. : . ::. : ..:.::: :::  : :.::. : 
XP_016 LVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVK
          750       760       770       780       790       800    

           550       560  
pF1KB9 ELAGQALQFTTLLTSLAP 
       ::. .. ::  .: .::  
XP_016 ELGHSTQQFRRVLGQLAAA
          810       820   

>--
 initn: 231 init1: 167 opt: 433  Z-score: 198.9  bits: 47.2 E(85289): 0.00024
Smith-Waterman score: 433; 39.0% identity (61.0% similar) in 218 aa overlap (9-212:53-255)

                                     10        20        30        
pF1KB9                       MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQRE
                                     ::.:::::.::::.:::::.::.. ::...
XP_016 GPQGTGQPCSCGHWAEGQGGPPEPAGGPNVLAKALYDNVAESPDELSFRKGDIMTVLEQD
             30        40        50        60        70        80  

       40        50        60               70        80        90 
pF1KB9 GAGGLDGWCLCSLHGQQGIVPANRVKLL-------PAGPAPKPSLSPASPAQPGSPYPAP
        . ::::: ::::::.:::::.::.:.:       ::::.: :  .::.: :::   :::
XP_016 -TQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQP-QPGLHAPAP
              90       100       110       120       130        140

             100       110       120        130       140       150
pF1KB9 DHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDL-IYKIPRASGTQLAAPRDALEVYDV
         :   : . ..:   .: : :   . : : . .  .:..:  :  :. .:     . ..
XP_016 PAS---QYTPMLPNTYQPQPDSVYLV-PTPSKAQQGLYQVPGPS-PQFQSP----PAKQT
                 150       160        170       180            190 

              160       170       180       190          200       
pF1KB9 PPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTP---KPPAELEPDLE--
          . ..:   :.  ::.    : .: : : :  .  :.:: .    .   .. :...  
XP_016 STFSKQTPHH-PFPSPAT---DLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTR
             200           210       220       230       240       

          210       220       230       240       250       260    
pF1KB9 -WEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPP
        ::: . :                                                    
XP_016 SWEGTKPPAKVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPD
       250       260       270       280       290       300       

>>XP_011521777 (OMIM: 602941) PREDICTED: breast cancer a  (841 aa)
 initn: 693 init1: 390 opt: 465  Z-score: 211.7  bits: 49.6 E(85289): 4.7e-05
Smith-Waterman score: 551; 30.5% identity (51.8% similar) in 587 aa overlap (58-560:279-839)

        30        40        50        60        70               80
pF1KB9 RGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPK-------PSLSPAS
                                     :: .  : .: ::  .       :... :.
XP_011 NGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAK
      250       260       270       280       290       300        

                    90       100       110       120       130     
pF1KB9 PAQPG-SPY----PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASG
       : .:. .:     : :: :   ..:: ::::: :   . :: :   :.:  .: .::   
XP_011 PFDPARTPLVLAAPPPD-SPPAEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPRERV
      310       320        330        340        350       360     

          140         150        160            170       180      
pF1KB9 TQ-LAAPRDALE--VYDVPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDA
           .:   ...  :: ::: : : .:. :     .:      :.  . .    ::..  
XP_011 LPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--
         370       380       390       400       410       420     

        190       200                      210       220       230 
pF1KB9 PYDVPLTPKPPAELEP----------DLEWEGG-----REPGPPIYAAPSNLKRASALLN
       : .. .. .  :.:.           ::   .:     : :. :     ..:. : : ..
XP_011 PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ
           430       440       450       460       470       480   

             240        250          260       270                 
pF1KB9 LYEAPEELLADGEGG-GTDEGIYDVPL---LGPEAPPSPEPPGALASHDQ----------
          : .:::  .... :.     :  :   :. .     .   .:..: :          
XP_011 --SAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSG
             490       500       510       520       530       540 

          280       290             300       310       320        
pF1KB9 ---DTLAQLLARSPPPPHRPR-LPS-----AESLSRRPLPALPVPEAPSPSPVPSPAPGR
          . : .:.: :   :.  . : :     :  : ::   . : ::. . .  :.:.  .
XP_011 ATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGG-TLHPNPTD-K
             550       560       570       580       590           

      330       340       350       360       370       380        
pF1KB9 KGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG
        .:::.:::: ::                    .:.: :.... ::  : :.::::::.:
XP_011 TSSIQSRPLPSPPKFTS----------------QDSPDGQYENSEGGWM-EDYDYVHLQG
     600       610                       620       630        640  

         390       400                410                    420   
pF1KB9 ---MDKAQGSRPPDQACT--GDPELP-------ER-----GMP--------APQEALSPG
          ..:.:       . :  :  .:        ::     . :        .: . :.::
XP_011 KEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPG
            650       660       670       680       690       700  

           430       440       450       460       470       480   
pF1KB9 EPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHR
       .   .. .: ::: ::  ::... ..:  :: :..... .::::..:: ::: :...::.
XP_011 RTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHK
            710       720       730       740       750       760  

           490       500       510       520       530       540   
pF1KB9 LVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVT
       :::.::::.: : .: .:.::   .. : . ::. : ..:.::: :::  : :.::. : 
XP_011 LVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVK
            770       780       790       800       810       820  

           550       560  
pF1KB9 ELAGQALQFTTLLTSLAP 
       ::. .. ::  .: .::  
XP_011 ELGHSTQQFRRVLGQLAAA
            830       840 

>>XP_005256317 (OMIM: 602941) PREDICTED: breast cancer a  (841 aa)
 initn: 693 init1: 390 opt: 465  Z-score: 211.7  bits: 49.6 E(85289): 4.7e-05
Smith-Waterman score: 551; 30.5% identity (51.8% similar) in 587 aa overlap (58-560:279-839)

        30        40        50        60        70               80
pF1KB9 RGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPK-------PSLSPAS
                                     :: .  : .: ::  .       :... :.
XP_005 NGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAK
      250       260       270       280       290       300        

                    90       100       110       120       130     
pF1KB9 PAQPG-SPY----PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASG
       : .:. .:     : :: :   ..:: ::::: :   . :: :   :.:  .: .::   
XP_005 PFDPARTPLVLAAPPPD-SPPAEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPRERV
      310       320        330        340        350       360     

          140         150        160            170       180      
pF1KB9 TQ-LAAPRDALE--VYDVPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDA
           .:   ...  :: ::: : : .:. :     .:      :.  . .    ::..  
XP_005 LPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--
         370       380       390       400       410       420     

        190       200                      210       220       230 
pF1KB9 PYDVPLTPKPPAELEP----------DLEWEGG-----REPGPPIYAAPSNLKRASALLN
       : .. .. .  :.:.           ::   .:     : :. :     ..:. : : ..
XP_005 PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ
           430       440       450       460       470       480   

             240        250          260       270                 
pF1KB9 LYEAPEELLADGEGG-GTDEGIYDVPL---LGPEAPPSPEPPGALASHDQ----------
          : .:::  .... :.     :  :   :. .     .   .:..: :          
XP_005 --SAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSG
             490       500       510       520       530       540 

          280       290             300       310       320        
pF1KB9 ---DTLAQLLARSPPPPHRPR-LPS-----AESLSRRPLPALPVPEAPSPSPVPSPAPGR
          . : .:.: :   :.  . : :     :  : ::   . : ::. . .  :.:.  .
XP_005 ATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGG-TLHPNPTD-K
             550       560       570       580       590           

      330       340       350       360       370       380        
pF1KB9 KGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG
        .:::.:::: ::                    .:.: :.... ::  : :.::::::.:
XP_005 TSSIQSRPLPSPPKFTS----------------QDSPDGQYENSEGGWM-EDYDYVHLQG
     600       610                       620       630        640  

         390       400                410                    420   
pF1KB9 ---MDKAQGSRPPDQACT--GDPELP-------ER-----GMP--------APQEALSPG
          ..:.:       . :  :  .:        ::     . :        .: . :.::
XP_005 KEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPG
            650       660       670       680       690       700  

           430       440       450       460       470       480   
pF1KB9 EPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHR
       .   .. .: ::: ::  ::... ..:  :: :..... .::::..:: ::: :...::.
XP_005 RTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHK
            710       720       730       740       750       760  

           490       500       510       520       530       540   
pF1KB9 LVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVT
       :::.::::.: : .: .:.::   .. : . ::. : ..:.::: :::  : :.::. : 
XP_005 LVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVK
            770       780       790       800       810       820  

           550       560  
pF1KB9 ELAGQALQFTTLLTSLAP 
       ::. .. ::  .: .::  
XP_005 ELGHSTQQFRRVLGQLAAA
            830       840 

>>NP_001164190 (OMIM: 602941) breast cancer anti-estroge  (868 aa)
 initn: 704 init1: 390 opt: 465  Z-score: 211.5  bits: 49.6 E(85289): 4.8e-05
Smith-Waterman score: 551; 30.5% identity (51.8% similar) in 587 aa overlap (58-560:306-866)

        30        40        50        60        70               80
pF1KB9 RGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPK-------PSLSPAS
                                     :: .  : .: ::  .       :... :.
NP_001 NGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAK
         280       290       300       310       320       330     

                    90       100       110       120       130     
pF1KB9 PAQPG-SPY----PAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASG
       : .:. .:     : :: :   ..:: ::::: :   . :: :   :.:  .: .::   
NP_001 PFDPARTPLVLAAPPPD-SPPAEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPRERV
         340       350        360        370        380       390  

          140         150        160            170       180      
pF1KB9 TQ-LAAPRDALE--VYDVPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDA
           .:   ...  :: ::: : : .:. :     .:      :.  . .    ::..  
NP_001 LPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--
            400       410       420       430       440       450  

        190       200                      210       220       230 
pF1KB9 PYDVPLTPKPPAELEP----------DLEWEGG-----REPGPPIYAAPSNLKRASALLN
       : .. .. .  :.:.           ::   .:     : :. :     ..:. : : ..
NP_001 PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ
              460       470       480       490       500       510

             240        250          260       270                 
pF1KB9 LYEAPEELLADGEGG-GTDEGIYDVPL---LGPEAPPSPEPPGALASHDQ----------
          : .:::  .... :.     :  :   :. .     .   .:..: :          
NP_001 --SAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSG
                520       530       540       550       560        

          280       290             300       310       320        
pF1KB9 ---DTLAQLLARSPPPPHRPR-LPS-----AESLSRRPLPALPVPEAPSPSPVPSPAPGR
          . : .:.: :   :.  . : :     :  : ::   . : ::. . .  :.:.  .
NP_001 ATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGG-TLHPNPTD-K
      570       580       590       600       610        620       

      330       340       350       360       370       380        
pF1KB9 KGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG
        .:::.:::: ::                    .:.: :.... ::  : :.::::::.:
NP_001 TSSIQSRPLPSPPKFTS----------------QDSPDGQYENSEGGWM-EDYDYVHLQG
        630       640                       650        660         

         390       400                410                    420   
pF1KB9 ---MDKAQGSRPPDQACT--GDPELP-------ER-----GMP--------APQEALSPG
          ..:.:       . :  :  .:        ::     . :        .: . :.::
NP_001 KEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPG
     670       680       690       700       710       720         

           430       440       450       460       470       480   
pF1KB9 EPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHR
       .   .. .: ::: ::  ::... ..:  :: :..... .::::..:: ::: :...::.
NP_001 RTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHK
     730       740       750       760       770       780         

           490       500       510       520       530       540   
pF1KB9 LVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVT
       :::.::::.: : .: .:.::   .. : . ::. : ..:.::: :::  : :.::. : 
NP_001 LVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVK
     790       800       810       820       830       840         

           550       560  
pF1KB9 ELAGQALQFTTLLTSLAP 
       ::. .. ::  .: .::  
NP_001 ELGHSTQQFRRVLGQLAAA
     850       860        

>--
 initn: 246 init1: 167 opt: 473  Z-score: 214.7  bits: 50.2 E(85289): 3.2e-05
Smith-Waterman score: 473; 35.2% identity (57.5% similar) in 315 aa overlap (9-297:5-296)

               10        20        30        40        50        60
pF1KB9 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA
               ::.:::::.::::.:::::.::.. ::... . ::::: ::::::.:::::.
NP_001     MENVLAKALYDNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPG
                   10        20        30         40        50     

                      70        80        90       100       110   
pF1KB9 NRVKLL-------PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTS
       ::.:.:       ::::.: :  .::.: :::   :::  :   : . ..:   .: : :
NP_001 NRLKILVGMYDKKPAGPGPGPPATPAQP-QPGLHAPAPPAS---QYTPMLPNTYQPQPDS
          60        70        80         90          100       110 

           120        130       140       150       160       170  
pF1KB9 GPPAGPCPPSPDL-IYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHP
          . : : . .  .:..:  :  :. .:     . ..   . ..:   :.  ::.    
NP_001 VYLV-PTPSKAQQGLYQVPGPS-PQFQSP----PAKQTSTFSKQTPHH-PFPSPAT---D
              120       130            140       150        160    

            180       190          200          210          220   
pF1KB9 LTRVAPQPPGEDDAPYDVPLTP---KPPAELEPDLE---WEGGREPGP---PIYAAPSNL
       : .: : : :  .  :.:: .    .   .. :...   ::: . :.    :  .. . .
NP_001 LYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYV
             170       180       190       200       210       220 

            230       240       250               260       270    
pF1KB9 KRASA-LLNLYEAPEELLADGEGGGTDEGIYDVP----LL----GPEAPPSPEPPGALAS
        .:.    . :. :..::: :      . :::::    ::    : :.  .: : .. . 
NP_001 YEAAQPEQDEYDIPRHLLAPGP-----QDIYDVPPVRGLLPSQYGQEVYDTP-PMAVKGP
             230       240            250       260        270     

          280       290       300       310       320       330    
pF1KB9 HDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD
       . .: :  : . . ::  .  ::                                     
NP_001 NGRDPL--LEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAK
         280         290       300       310       320       330   




561 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:03:34 2016 done: Sat Nov  5 15:03:36 2016
 Total Scan time: 13.320 Total Display time:  0.110

Function used was FASTA [36.3.4 Apr, 2011]
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