FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9986, 712 aa 1>>>pF1KB9986 712 - 712 aa - 712 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3818+/-0.00107; mu= 14.5917+/- 0.064 mean_var=80.3737+/-16.226, 0's: 0 Z-trim(103.5): 22 B-trim: 0 in 0/50 Lambda= 0.143060 statistics sampled from 7445 (7450) to 7445 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.229), width: 16 Scan time: 2.540 The best scores are: opt bits E(32554) CCDS5012.1 ORC3 gene_id:23595|Hs108|chr6 ( 712) 4673 974.7 0 CCDS43486.1 ORC3 gene_id:23595|Hs108|chr6 ( 711) 4656 971.2 0 CCDS56440.1 ORC3 gene_id:23595|Hs108|chr6 ( 568) 3716 777.2 0 >>CCDS5012.1 ORC3 gene_id:23595|Hs108|chr6 (712 aa) initn: 4673 init1: 4673 opt: 4673 Z-score: 5210.9 bits: 974.7 E(32554): 0 Smith-Waterman score: 4673; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:1-712) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC 670 680 690 700 710 >>CCDS43486.1 ORC3 gene_id:23595|Hs108|chr6 (711 aa) initn: 3331 init1: 3331 opt: 4656 Z-score: 5191.9 bits: 971.2 E(32554): 0 Smith-Waterman score: 4656; 99.9% identity (99.9% similar) in 712 aa overlap (1-712:1-711) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: CCDS43 SYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 600 610 620 630 640 650 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC 660 670 680 690 700 710 >>CCDS56440.1 ORC3 gene_id:23595|Hs108|chr6 (568 aa) initn: 2391 init1: 2391 opt: 3716 Z-score: 4145.0 bits: 777.2 E(32554): 0 Smith-Waterman score: 3716; 99.8% identity (99.8% similar) in 569 aa overlap (144-712:1-568) 120 130 140 150 160 170 pF1KB9 HDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVT :::::::::::::::::::::::::::::: CCDS56 MKHFLQKLISQLMDCCVDIKSKEEESVHVT 10 20 30 180 190 200 210 220 230 pF1KB9 QRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 QRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDF 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB9 IIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 IIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLL 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB9 LTTQFPFKINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LTTQFPFKINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKR 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB9 RINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 RINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYF 220 230 240 250 260 270 420 430 440 450 460 470 pF1KB9 LVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILE 280 290 300 310 320 330 480 490 500 510 520 530 pF1KB9 KCFKVFKSYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKS :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: CCDS56 KCFKVFKSYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQPKGLQKTDLYHLQKS 340 350 360 370 380 540 550 560 570 580 590 pF1KB9 LLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLN 390 400 410 420 430 440 600 610 620 630 640 650 pF1KB9 AAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 AAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAF 450 460 470 480 490 500 660 670 680 690 700 710 pF1KB9 ATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC 510 520 530 540 550 560 712 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:04:53 2016 done: Sat Nov 5 16:04:53 2016 Total Scan time: 2.540 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]