FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9986, 712 aa 1>>>pF1KB9986 712 - 712 aa - 712 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2136+/-0.000472; mu= 15.7550+/- 0.029 mean_var=88.2067+/-18.883, 0's: 0 Z-trim(110.8): 26 B-trim: 903 in 2/48 Lambda= 0.136560 statistics sampled from 19165 (19182) to 19165 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.225), width: 16 Scan time: 9.570 The best scores are: opt bits E(85289) NP_862820 (OMIM: 604972) origin recognition comple ( 712) 4673 931.4 0 NP_036513 (OMIM: 604972) origin recognition comple ( 711) 4656 928.1 0 XP_005248761 (OMIM: 604972) PREDICTED: origin reco ( 684) 4444 886.3 0 XP_016866121 (OMIM: 604972) PREDICTED: origin reco ( 687) 4435 884.5 0 XP_016866123 (OMIM: 604972) PREDICTED: origin reco ( 683) 4427 883.0 0 XP_016866122 (OMIM: 604972) PREDICTED: origin reco ( 686) 4418 881.2 0 XP_005248762 (OMIM: 604972) PREDICTED: origin reco ( 659) 4313 860.5 0 XP_005248763 (OMIM: 604972) PREDICTED: origin reco ( 659) 4313 860.5 0 XP_016866125 (OMIM: 604972) PREDICTED: origin reco ( 658) 4296 857.1 0 XP_016866126 (OMIM: 604972) PREDICTED: origin reco ( 658) 4296 857.1 0 XP_016866127 (OMIM: 604972) PREDICTED: origin reco ( 630) 4067 812.0 0 XP_016866128 (OMIM: 604972) PREDICTED: origin reco ( 630) 4067 812.0 0 NP_001184188 (OMIM: 604972) origin recognition com ( 568) 3716 742.8 8.3e-214 XP_011533954 (OMIM: 604972) PREDICTED: origin reco ( 479) 3035 608.6 1.8e-173 XP_011533953 (OMIM: 604972) PREDICTED: origin reco ( 674) 2533 509.8 1.4e-143 XP_016866124 (OMIM: 604972) PREDICTED: origin reco ( 673) 1920 389.0 3.1e-107 XP_016866129 (OMIM: 604972) PREDICTED: origin reco ( 620) 1560 318.1 6.6e-86 >>NP_862820 (OMIM: 604972) origin recognition complex su (712 aa) initn: 4673 init1: 4673 opt: 4673 Z-score: 4977.0 bits: 931.4 E(85289): 0 Smith-Waterman score: 4673; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:1-712) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC 670 680 690 700 710 >>NP_036513 (OMIM: 604972) origin recognition complex su (711 aa) initn: 3331 init1: 3331 opt: 4656 Z-score: 4958.9 bits: 928.1 E(85289): 0 Smith-Waterman score: 4656; 99.9% identity (99.9% similar) in 712 aa overlap (1-712:1-711) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: NP_036 SYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 600 610 620 630 640 650 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC 660 670 680 690 700 710 >>XP_005248761 (OMIM: 604972) PREDICTED: origin recognit (684 aa) initn: 4444 init1: 4444 opt: 4444 Z-score: 4733.4 bits: 886.3 E(85289): 0 Smith-Waterman score: 4444; 100.0% identity (100.0% similar) in 678 aa overlap (1-678:1-678) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::: XP_005 EKMDANSATSEEMNEIIHLQCSVY 670 680 >>XP_016866121 (OMIM: 604972) PREDICTED: origin recognit (687 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 4723.8 bits: 884.5 E(85289): 0 Smith-Waterman score: 4435; 99.9% identity (100.0% similar) in 678 aa overlap (1-678:1-678) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::. XP_016 EKMDANSATSEEMNEIIQEYTAPVYRK 670 680 >>XP_016866123 (OMIM: 604972) PREDICTED: origin recognit (683 aa) initn: 3331 init1: 3331 opt: 4427 Z-score: 4715.3 bits: 883.0 E(85289): 0 Smith-Waterman score: 4427; 99.9% identity (99.9% similar) in 678 aa overlap (1-678:1-677) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: XP_016 SYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 600 610 620 630 640 650 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::: XP_016 EKMDANSATSEEMNEIIHLQCSVY 660 670 680 >>XP_016866122 (OMIM: 604972) PREDICTED: origin recognit (686 aa) initn: 4428 init1: 3331 opt: 4418 Z-score: 4705.7 bits: 881.2 E(85289): 0 Smith-Waterman score: 4418; 99.7% identity (99.9% similar) in 678 aa overlap (1-678:1-677) 10 20 30 40 50 60 pF1KB9 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSSMSKGCFVFKPNSKKRKISLPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEELNKNLFDNLIEFLQKSHSGFQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINEKVLQVLTNIFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 SYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: XP_016 SYCENHLGSTAKRIEEFLAQFQSLD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKEL 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIAL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAA 600 610 620 630 640 650 670 680 690 700 710 pF1KB9 EKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC :::::::::::::::::. XP_016 EKMDANSATSEEMNEIIQEYTAPVYRK 660 670 680 >>XP_005248762 (OMIM: 604972) PREDICTED: origin recognit (659 aa) initn: 4313 init1: 4313 opt: 4313 Z-score: 4594.2 bits: 860.5 E(85289): 0 Smith-Waterman score: 4313; 100.0% identity (100.0% similar) in 659 aa overlap (54-712:1-659) 30 40 50 60 70 80 pF1KB9 LPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG :::::::::::::::::::::::::::::: XP_005 MKSENERLQEELNKNLFDNLIEFLQKSHSG 10 20 30 90 100 110 120 130 140 pF1KB9 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB9 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB9 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB9 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB9 LDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB9 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB9 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR 580 590 600 610 620 630 690 700 710 pF1KB9 AVSELELLGFIKPTKQKTDHVARLTWGGC ::::::::::::::::::::::::::::: XP_005 AVSELELLGFIKPTKQKTDHVARLTWGGC 640 650 >>XP_005248763 (OMIM: 604972) PREDICTED: origin recognit (659 aa) initn: 4313 init1: 4313 opt: 4313 Z-score: 4594.2 bits: 860.5 E(85289): 0 Smith-Waterman score: 4313; 100.0% identity (100.0% similar) in 659 aa overlap (54-712:1-659) 30 40 50 60 70 80 pF1KB9 LPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG :::::::::::::::::::::::::::::: XP_005 MKSENERLQEELNKNLFDNLIEFLQKSHSG 10 20 30 90 100 110 120 130 140 pF1KB9 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB9 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB9 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB9 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB9 LDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB9 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB9 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR 580 590 600 610 620 630 690 700 710 pF1KB9 AVSELELLGFIKPTKQKTDHVARLTWGGC ::::::::::::::::::::::::::::: XP_005 AVSELELLGFIKPTKQKTDHVARLTWGGC 640 650 >>XP_016866125 (OMIM: 604972) PREDICTED: origin recognit (658 aa) initn: 2971 init1: 2971 opt: 4296 Z-score: 4576.1 bits: 857.1 E(85289): 0 Smith-Waterman score: 4296; 99.8% identity (99.8% similar) in 659 aa overlap (54-712:1-658) 30 40 50 60 70 80 pF1KB9 LPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG :::::::::::::::::::::::::::::: XP_016 MKSENERLQEELNKNLFDNLIEFLQKSHSG 10 20 30 90 100 110 120 130 140 pF1KB9 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB9 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB9 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB9 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB9 LDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL 460 470 480 490 500 570 580 590 600 610 620 pF1KB9 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI 510 520 530 540 550 560 630 640 650 660 670 680 pF1KB9 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR 570 580 590 600 610 620 690 700 710 pF1KB9 AVSELELLGFIKPTKQKTDHVARLTWGGC ::::::::::::::::::::::::::::: XP_016 AVSELELLGFIKPTKQKTDHVARLTWGGC 630 640 650 >>XP_016866126 (OMIM: 604972) PREDICTED: origin recognit (658 aa) initn: 2971 init1: 2971 opt: 4296 Z-score: 4576.1 bits: 857.1 E(85289): 0 Smith-Waterman score: 4296; 99.8% identity (99.8% similar) in 659 aa overlap (54-712:1-658) 30 40 50 60 70 80 pF1KB9 LPIEDYFNKGKNEPEDSKLRFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG :::::::::::::::::::::::::::::: XP_016 MKSENERLQEELNKNLFDNLIEFLQKSHSG 10 20 30 90 100 110 120 130 140 pF1KB9 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQKNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKK 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNIFLYHDFSVQN 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB9 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEK 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB9 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCL 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB9 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQS 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB9 LDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LD-ETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCL 460 470 480 490 500 570 580 590 600 610 620 pF1KB9 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREYLLPPETQPLHEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCI 510 520 530 540 550 560 630 640 650 660 670 680 pF1KB9 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIR 570 580 590 600 610 620 690 700 710 pF1KB9 AVSELELLGFIKPTKQKTDHVARLTWGGC ::::::::::::::::::::::::::::: XP_016 AVSELELLGFIKPTKQKTDHVARLTWGGC 630 640 650 712 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:04:54 2016 done: Sat Nov 5 16:04:55 2016 Total Scan time: 9.570 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]