FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9987, 574 aa 1>>>pF1KB9987 574 - 574 aa - 574 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3303+/-0.00095; mu= -2.7775+/- 0.057 mean_var=281.8081+/-57.183, 0's: 0 Z-trim(115.3): 12 B-trim: 226 in 2/50 Lambda= 0.076401 statistics sampled from 15853 (15862) to 15853 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.487), width: 16 Scan time: 4.210 The best scores are: opt bits E(32554) CCDS5092.1 TRAF3IP2 gene_id:10758|Hs108|chr6 ( 574) 4020 456.4 4.5e-128 CCDS5093.1 TRAF3IP2 gene_id:10758|Hs108|chr6 ( 565) 3956 449.3 5.9e-126 CCDS55050.1 TRAF3IP2 gene_id:10758|Hs108|chr6 ( 564) 3938 447.3 2.3e-125 CCDS55049.1 TRAF3IP2 gene_id:10758|Hs108|chr6 ( 109) 743 94.7 6.5e-20 >>CCDS5092.1 TRAF3IP2 gene_id:10758|Hs108|chr6 (574 aa) initn: 4020 init1: 4020 opt: 4020 Z-score: 2412.9 bits: 456.4 E(32554): 4.5e-128 Smith-Waterman score: 4020; 99.8% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS50 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 490 500 510 520 530 540 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: CCDS50 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 550 560 570 >>CCDS5093.1 TRAF3IP2 gene_id:10758|Hs108|chr6 (565 aa) initn: 3956 init1: 3956 opt: 3956 Z-score: 2374.8 bits: 449.3 E(32554): 5.9e-126 Smith-Waterman score: 3956; 99.8% identity (100.0% similar) in 565 aa overlap (10-574:1-565) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS50 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 480 490 500 510 520 530 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: CCDS50 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 540 550 560 >>CCDS55050.1 TRAF3IP2 gene_id:10758|Hs108|chr6 (564 aa) initn: 3208 init1: 3208 opt: 3938 Z-score: 2364.1 bits: 447.3 E(32554): 2.3e-125 Smith-Waterman score: 3938; 99.6% identity (99.8% similar) in 565 aa overlap (10-574:1-564) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS55 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS55 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRD-TVMIIVAISPKYKQDVE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 480 490 500 510 520 530 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: CCDS55 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 540 550 560 >>CCDS55049.1 TRAF3IP2 gene_id:10758|Hs108|chr6 (109 aa) initn: 743 init1: 743 opt: 743 Z-score: 471.0 bits: 94.7 E(32554): 6.5e-20 Smith-Waterman score: 743; 100.0% identity (100.0% similar) in 109 aa overlap (466-574:1-109) 440 450 460 470 480 490 pF1KB9 FQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHT :::::::::::::::::::::::::::::: CCDS55 MIIVAISPKYKQDVEGAESQLDEDEHGLHT 10 20 30 500 510 520 530 540 550 pF1KB9 KYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLRE 40 50 60 70 80 90 560 570 pF1KB9 EEYVAPPRGPLPTLQVVPL ::::::::::::::::::: CCDS55 EEYVAPPRGPLPTLQVVPL 100 574 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:05:33 2016 done: Sat Nov 5 16:05:33 2016 Total Scan time: 4.210 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]