FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9987, 574 aa 1>>>pF1KB9987 574 - 574 aa - 574 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.3100+/-0.000387; mu= -8.6178+/- 0.024 mean_var=333.2613+/-68.266, 0's: 0 Z-trim(123.0): 7 B-trim: 121 in 1/56 Lambda= 0.070256 statistics sampled from 41982 (41992) to 41982 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.492), width: 16 Scan time: 12.770 The best scores are: opt bits E(85289) NP_671733 (OMIM: 607043,614070,615527) adapter pro ( 574) 4020 421.2 4.4e-117 XP_011533688 (OMIM: 607043,614070,615527) PREDICTE ( 574) 4020 421.2 4.4e-117 NP_679211 (OMIM: 607043,614070,615527) adapter pro ( 565) 3956 414.7 3.9e-115 NP_001157753 (OMIM: 607043,614070,615527) adapter ( 564) 3938 412.9 1.4e-114 NP_001157755 (OMIM: 607043,614070,615527) adapter ( 109) 743 88.6 1.1e-17 XP_006715382 (OMIM: 607043,614070,615527) PREDICTE ( 109) 743 88.6 1.1e-17 >>NP_671733 (OMIM: 607043,614070,615527) adapter protein (574 aa) initn: 4020 init1: 4020 opt: 4020 Z-score: 2223.0 bits: 421.2 E(85289): 4.4e-117 Smith-Waterman score: 4020; 99.8% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_671 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_671 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 490 500 510 520 530 540 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: NP_671 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 550 560 570 >>XP_011533688 (OMIM: 607043,614070,615527) PREDICTED: a (574 aa) initn: 4020 init1: 4020 opt: 4020 Z-score: 2223.0 bits: 421.2 E(85289): 4.4e-117 Smith-Waterman score: 4020; 99.8% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_011 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 490 500 510 520 530 540 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: XP_011 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 550 560 570 >>NP_679211 (OMIM: 607043,614070,615527) adapter protein (565 aa) initn: 3956 init1: 3956 opt: 3956 Z-score: 2188.0 bits: 414.7 E(85289): 3.9e-115 Smith-Waterman score: 3956; 99.8% identity (100.0% similar) in 565 aa overlap (10-574:1-565) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 MNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_679 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_679 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 480 490 500 510 520 530 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: NP_679 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 540 550 560 >>NP_001157753 (OMIM: 607043,614070,615527) adapter prot (564 aa) initn: 3208 init1: 3208 opt: 3938 Z-score: 2178.2 bits: 412.9 E(85289): 1.4e-114 Smith-Waterman score: 3938; 99.6% identity (99.8% similar) in 565 aa overlap (10-574:1-564) 10 20 30 40 50 60 pF1KB9 MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPT 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 PALPGQPLPGASVRGLHPVQKVILNYPSPWDQEERPAQRDCSFPGLPRHQDQPHHQPPNR :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_001 PALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVE :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: NP_001 AMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRD-TVMIIVAISPKYKQDVE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYS 480 490 500 510 520 530 550 560 570 pF1KB9 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL :::::::::::::::::::::::::::::::::: NP_001 WPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL 540 550 560 >>NP_001157755 (OMIM: 607043,614070,615527) adapter prot (109 aa) initn: 743 init1: 743 opt: 743 Z-score: 438.2 bits: 88.6 E(85289): 1.1e-17 Smith-Waterman score: 743; 100.0% identity (100.0% similar) in 109 aa overlap (466-574:1-109) 440 450 460 470 480 490 pF1KB9 FQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHT :::::::::::::::::::::::::::::: NP_001 MIIVAISPKYKQDVEGAESQLDEDEHGLHT 10 20 30 500 510 520 530 540 550 pF1KB9 KYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLRE 40 50 60 70 80 90 560 570 pF1KB9 EEYVAPPRGPLPTLQVVPL ::::::::::::::::::: NP_001 EEYVAPPRGPLPTLQVVPL 100 >>XP_006715382 (OMIM: 607043,614070,615527) PREDICTED: a (109 aa) initn: 743 init1: 743 opt: 743 Z-score: 438.2 bits: 88.6 E(85289): 1.1e-17 Smith-Waterman score: 743; 100.0% identity (100.0% similar) in 109 aa overlap (466-574:1-109) 440 450 460 470 480 490 pF1KB9 FQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHT :::::::::::::::::::::::::::::: XP_006 MIIVAISPKYKQDVEGAESQLDEDEHGLHT 10 20 30 500 510 520 530 540 550 pF1KB9 KYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLRE 40 50 60 70 80 90 560 570 pF1KB9 EEYVAPPRGPLPTLQVVPL ::::::::::::::::::: XP_006 EEYVAPPRGPLPTLQVVPL 100 574 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:05:34 2016 done: Sat Nov 5 16:05:35 2016 Total Scan time: 12.770 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]