FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0001, 497 aa 1>>>pF1KE0001 497 - 497 aa - 497 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5732+/-0.000357; mu= 17.8598+/- 0.022 mean_var=86.6234+/-17.261, 0's: 0 Z-trim(114.4): 73 B-trim: 0 in 0/55 Lambda= 0.137802 statistics sampled from 24197 (24270) to 24197 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.285), width: 16 Scan time: 9.500 The best scores are: opt bits E(85289) NP_113664 (OMIM: 612434) cysteine-rich secretory p ( 497) 3545 714.9 1.3e-205 XP_005256247 (OMIM: 612434) PREDICTED: cysteine-ri ( 497) 3545 714.9 1.3e-205 NP_056970 (OMIM: 607076) peptidase inhibitor 15 pr ( 258) 975 203.7 5.1e-52 NP_001311332 (OMIM: 607076) peptidase inhibitor 15 ( 258) 975 203.7 5.1e-52 NP_006842 (OMIM: 602692) glioma pathogenesis-relat ( 266) 454 100.2 7.9e-21 NP_689992 (OMIM: 610395) GLIPR1-like protein 1 iso ( 233) 361 81.6 2.6e-15 NP_001291893 (OMIM: 610395) GLIPR1-like protein 1 ( 242) 361 81.7 2.7e-15 XP_011536436 (OMIM: 610395) PREDICTED: GLIPR1-like ( 301) 361 81.7 3.2e-15 NP_689649 (OMIM: 610394) GLIPR1-like protein 2 iso ( 253) 355 80.5 6.4e-15 NP_001257325 (OMIM: 610394) GLIPR1-like protein 2 ( 344) 355 80.6 8e-15 XP_011521339 (OMIM: 616573) PREDICTED: C-type lect ( 329) 322 74.0 7.3e-13 XP_011521337 (OMIM: 616573) PREDICTED: C-type lect ( 396) 322 74.1 8.5e-13 XP_006721242 (OMIM: 616573) PREDICTED: C-type lect ( 451) 322 74.1 9.4e-13 XP_011521336 (OMIM: 616573) PREDICTED: C-type lect ( 451) 322 74.1 9.4e-13 NP_001122 (OMIM: 601193) cysteine-rich secretory p ( 249) 306 70.7 5.4e-12 NP_001192149 (OMIM: 601193) cysteine-rich secretor ( 249) 306 70.7 5.4e-12 XP_016878698 (OMIM: 616571) PREDICTED: C-type lect ( 324) 289 67.4 6.8e-11 XP_005255991 (OMIM: 616571) PREDICTED: C-type lect ( 446) 289 67.5 8.8e-11 NP_872425 (OMIM: 616571) C-type lectin domain fami ( 446) 289 67.5 8.8e-11 NP_001258126 (OMIM: 616571) C-type lectin domain f ( 446) 289 67.5 8.8e-11 NP_001129686 (OMIM: 616571) C-type lectin domain f ( 446) 289 67.5 8.8e-11 NP_775890 (OMIM: 616573) C-type lectin domain fami ( 446) 289 67.5 8.8e-11 XP_016878745 (OMIM: 616572) PREDICTED: C-type lect ( 324) 287 67.0 9e-11 XP_016878695 (OMIM: 616571) PREDICTED: C-type lect ( 476) 289 67.6 9.2e-11 XP_005256033 (OMIM: 616572) PREDICTED: C-type lect ( 446) 287 67.2 1.2e-10 XP_016878744 (OMIM: 616572) PREDICTED: C-type lect ( 446) 287 67.2 1.2e-10 NP_001011880 (OMIM: 616572) C-type lectin domain f ( 455) 287 67.2 1.2e-10 XP_016874337 (OMIM: 610394) PREDICTED: GLIPR1-like ( 267) 273 64.2 5.4e-10 NP_001135889 (OMIM: 187430) cysteine-rich secretor ( 243) 267 63.0 1.1e-09 NP_001135880 (OMIM: 187430) cysteine-rich secretor ( 243) 267 63.0 1.1e-09 NP_003287 (OMIM: 187430) cysteine-rich secretory p ( 243) 267 63.0 1.1e-09 NP_001135879 (OMIM: 187430) cysteine-rich secretor ( 243) 267 63.0 1.1e-09 NP_001248751 (OMIM: 187430) cysteine-rich secretor ( 243) 267 63.0 1.1e-09 NP_001135907 (OMIM: 187430) cysteine-rich secretor ( 243) 267 63.0 1.1e-09 XP_011513145 (OMIM: 187430) PREDICTED: cysteine-ri ( 252) 267 63.0 1.2e-09 XP_005249408 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_011513144 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_005249407 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_011513143 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_005249413 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_005249406 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_005249410 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_005249409 (OMIM: 187430) PREDICTED: cysteine-ri ( 278) 267 63.0 1.3e-09 XP_011536077 (OMIM: 602692) PREDICTED: glioma path ( 266) 243 58.2 3.3e-08 NP_733758 (OMIM: 601193) cysteine-rich secretory p ( 178) 225 54.5 2.9e-07 XP_011536252 (OMIM: 610394) PREDICTED: GLIPR1-like ( 237) 207 51.0 4.4e-06 XP_016874338 (OMIM: 610394) PREDICTED: GLIPR1-like ( 237) 207 51.0 4.4e-06 XP_011536251 (OMIM: 610394) PREDICTED: GLIPR1-like ( 237) 207 51.0 4.4e-06 XP_011513146 (OMIM: 187430) PREDICTED: cysteine-ri ( 145) 201 49.7 6.8e-06 XP_016865810 (OMIM: 601193) PREDICTED: cysteine-ri ( 147) 201 49.7 6.9e-06 >>NP_113664 (OMIM: 612434) cysteine-rich secretory prote (497 aa) initn: 3545 init1: 3545 opt: 3545 Z-score: 3812.3 bits: 714.9 E(85289): 1.3e-205 Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 497 aa overlap (1-497:1-497) 10 20 30 40 50 60 pF1KE0 MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 YRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 RKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 TPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 STCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 STCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 KSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 PSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSES 430 440 450 460 470 480 490 pF1KE0 LGTPRDGKAFRIFAVRQ ::::::::::::::::: NP_113 LGTPRDGKAFRIFAVRQ 490 >>XP_005256247 (OMIM: 612434) PREDICTED: cysteine-rich s (497 aa) initn: 3545 init1: 3545 opt: 3545 Z-score: 3812.3 bits: 714.9 E(85289): 1.3e-205 Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 497 aa overlap (1-497:1-497) 10 20 30 40 50 60 pF1KE0 MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 MLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 YRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 TPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 STCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 PSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSES 430 440 450 460 470 480 490 pF1KE0 LGTPRDGKAFRIFAVRQ ::::::::::::::::: XP_005 LGTPRDGKAFRIFAVRQ 490 >>NP_056970 (OMIM: 607076) peptidase inhibitor 15 prepro (258 aa) initn: 956 init1: 956 opt: 975 Z-score: 1054.9 bits: 203.7 E(85289): 5.1e-52 Smith-Waterman score: 975; 64.9% identity (83.8% similar) in 191 aa overlap (45-235:56-246) 20 30 40 50 60 70 pF1KE0 FLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQA .: .: : ..: :: ::..::.: : : NP_056 NSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPA 30 40 50 60 70 80 80 90 100 110 120 130 pF1KE0 SNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGRYRSPGFHVQSWYDE .:::::.::..: ::: :::. :::.:::. :: .::::... ::::: :. :::: NP_056 ANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDE 90 100 110 120 130 140 140 150 160 170 180 190 pF1KE0 VKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAV ::::..:::..::: :: :: :::::::::.::::.:.::::..::..:.::: ::. :: NP_056 VKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAV 150 160 170 180 190 200 200 210 220 230 240 250 pF1KE0 YFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVET :.::::.:::::::::::: : ::: ::::::::: .:::. NP_056 YLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK 210 220 230 240 250 260 270 280 290 300 310 pF1KE0 APIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLN >>NP_001311332 (OMIM: 607076) peptidase inhibitor 15 pre (258 aa) initn: 956 init1: 956 opt: 975 Z-score: 1054.9 bits: 203.7 E(85289): 5.1e-52 Smith-Waterman score: 975; 64.9% identity (83.8% similar) in 191 aa overlap (45-235:56-246) 20 30 40 50 60 70 pF1KE0 FLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQA .: .: : ..: :: ::..::.: : : NP_001 NSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPA 30 40 50 60 70 80 80 90 100 110 120 130 pF1KE0 SNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGRYRSPGFHVQSWYDE .:::::.::..: ::: :::. :::.:::. :: .::::... ::::: :. :::: NP_001 ANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDE 90 100 110 120 130 140 140 150 160 170 180 190 pF1KE0 VKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAV ::::..:::..::: :: :: :::::::::.::::.:.::::..::..:.::: ::. :: NP_001 VKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAV 150 160 170 180 190 200 200 210 220 230 240 250 pF1KE0 YFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVET :.::::.:::::::::::: : ::: ::::::::: .:::. NP_001 YLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK 210 220 230 240 250 260 270 280 290 300 310 pF1KE0 APIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLN >>NP_006842 (OMIM: 602692) glioma pathogenesis-related p (266 aa) initn: 406 init1: 163 opt: 454 Z-score: 495.0 bits: 100.2 E(85289): 7.9e-21 Smith-Waterman score: 454; 36.3% identity (60.1% similar) in 223 aa overlap (25-234:5-206) 10 20 30 40 50 pF1KE0 MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPRED-KEEI : ... . ..:.:.:. . . : :: .. NP_006 MRVTLATIAWMVSFVSNYSHTAN---ILPDIENEDFIKDC 10 20 30 60 70 80 90 100 110 pF1KE0 LMLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHG-----PTSL---LVSIG . .:::.:..:.: ::.: ::::: : . : ::::.: . :. : .: ..:.: NP_006 VRIHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLG 40 50 60 70 80 90 120 130 140 150 160 pF1KE0 QNLGAHWGRYRSPGFHVQS----WYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVW .:. : : : :.: ::::..:: . : .: ::::.:: NP_006 ENI---W-TGSVPIFSVSSAITNWYDEIQDYDFK----------TRICKKVCGHYTQVVW 100 110 120 130 140 170 180 190 200 210 220 pF1KE0 ATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGG : . :.::::. : :.. . .. :...:.:::.: ::. ::: : :: :: . NP_006 ADSYKVGCAVQFCPKVSGF-DALSNGAHFICNYGPGGNY-PTWPYKRGATCSACPNN--D 150 160 170 180 190 230 240 250 260 270 280 pF1KE0 SCRNNLCYREETYTPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQV .: .::: NP_006 KCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNRYTSLFLIVNSVILILSVIITILVQHKY 200 210 220 230 240 250 >>NP_689992 (OMIM: 610395) GLIPR1-like protein 1 isoform (233 aa) initn: 375 init1: 168 opt: 361 Z-score: 395.8 bits: 81.6 E(85289): 2.6e-15 Smith-Waterman score: 379; 36.1% identity (57.2% similar) in 180 aa overlap (63-234:41-203) 40 50 60 70 80 90 pF1KE0 ELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAA ::. ::.:.: :..:.:: :: : : : : NP_689 WILGLCLVATTSSKIPSITDPHFIDNCIEAHNEWRGKVNPPAADMKYMIWDKGLAKMAKA 20 30 40 50 60 70 100 110 120 130 140 pF1KE0 WASQCIWEHGPT--------SLLVSIGQNLGAHWGRYRSPGFHVQSWYDEVKDYTYPYPS ::.:: .::. . . .:.:. . .: . .::.:.. : . : NP_689 WANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLS 80 90 100 110 120 130 150 160 170 180 190 200 pF1KE0 ECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKG :: .: ::::.:::.. .:::: : .. : ... :::::.: : NP_689 ---------CSR-VCGHYTQLVWANSFYVGCAVAMCPNLG--GA---STAIFVCNYGPAG 140 150 160 170 210 220 230 240 250 260 pF1KE0 NWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVETAPIPEENHVW :. . :: :. :: : : .: .::: NP_689 NFANMPPYVRGESCSLC--SKEEKCVKNLCKNPFLKPTGRAPQQTAFNPFSLGFLLLRIF 180 190 200 210 220 230 >>NP_001291893 (OMIM: 610395) GLIPR1-like protein 1 isof (242 aa) initn: 375 init1: 168 opt: 361 Z-score: 395.6 bits: 81.7 E(85289): 2.7e-15 Smith-Waterman score: 385; 35.1% identity (56.4% similar) in 188 aa overlap (63-242:41-211) 40 50 60 70 80 90 pF1KE0 ELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAA ::. ::.:.: :..:.:: :: : : : : NP_001 WILGLCLVATTSSKIPSITDPHFIDNCIEAHNEWRGKVNPPAADMKYMIWDKGLAKMAKA 20 30 40 50 60 70 100 110 120 130 140 pF1KE0 WASQCIWEHGPT--------SLLVSIGQNLGAHWGRYRSPGFHVQSWYDEVKDYTYPYPS ::.:: .::. . . .:.:. . .: . .::.:.. : . : NP_001 WANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLS 80 90 100 110 120 130 150 160 170 180 190 200 pF1KE0 ECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKG :: .: ::::.:::.. .:::: : .. : . ... :::::.: : NP_001 ---------CSR-VCGHYTQLVWANSFYVGCAVAMCPNL---GGA--STAIFVCNYGPAG 140 150 160 170 210 220 230 240 250 260 pF1KE0 NWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVETAPIPEENHVW :. . :: :. :: : : .: .::: . : NP_001 NFANMPPYVRGESCSLC--SKEEKCVKNLCRTPQLIIPNQNPFLKPTGRAPQQTAFNPFS 180 190 200 210 220 230 270 280 290 300 310 320 pF1KE0 LQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLNHKAKIFGTLF NP_001 LGFLLLRIF 240 >>XP_011536436 (OMIM: 610395) PREDICTED: GLIPR1-like pro (301 aa) initn: 350 init1: 168 opt: 361 Z-score: 394.3 bits: 81.7 E(85289): 3.2e-15 Smith-Waterman score: 379; 36.1% identity (57.2% similar) in 180 aa overlap (63-234:126-288) 40 50 60 70 80 90 pF1KE0 ELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAA ::. ::.:.: :..:.:: :: : : : : XP_011 WILGLCLVATTSSKIPSITDPHFIDNCIEAHNEWRGKVNPPAADMKYMIWDKGLAKMAKA 100 110 120 130 140 150 100 110 120 130 140 pF1KE0 WASQCIWEHGPT--------SLLVSIGQNLGAHWGRYRSPGFHVQSWYDEVKDYTYPYPS ::.:: .::. . . .:.:. . .: . .::.:.. : . : XP_011 WANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLS 160 170 180 190 200 210 150 160 170 180 190 200 pF1KE0 ECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKG :: .: ::::.:::.. .:::: : .. : ... :::::.: : XP_011 ---------CSR-VCGHYTQLVWANSFYVGCAVAMCPNLG--GA---STAIFVCNYGPAG 220 230 240 250 260 210 220 230 240 250 260 pF1KE0 NWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVETAPIPEENHVW :. . :: :. :: : : .: .::: XP_011 NFANMPPYVRGESCSLC--SKEEKCVKNLCNYFLMKCWMLLEW 270 280 290 300 >>NP_689649 (OMIM: 610394) GLIPR1-like protein 2 isoform (253 aa) initn: 261 init1: 168 opt: 355 Z-score: 388.9 bits: 80.5 E(85289): 6.4e-15 Smith-Waterman score: 365; 32.5% identity (60.0% similar) in 200 aa overlap (49-236:43-225) 20 30 40 50 60 70 pF1KE0 GSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDK----EEILMLHNKLRGQVQPQA : .: :. .: . :::.:::.: :.. NP_689 AQSLPLAVGGVLKLRLCELWLLLLGSSLNARFLPDEEDVDFINEYVNLHNELRGDVIPRG 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNMEYMTWDDELEKSAAAWASQCIWEHG---PTSLLV-----SIGQNLGAHWGRYRSPGF ::...:::: : ..: ::...:.. :. .: .::.:. . . .. NP_689 SNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENMWVGPENEFTASI 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE0 HVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVW ..::. : : :.. : ::: :..: :.:: . :.::::. : :. NP_689 AIRSWHAEKKMYNFENGS---------CSGD-CSNYIQLVWDHSYKVGCAVTPCSKI--- 140 150 160 170 190 200 210 220 230 240 pF1KE0 GEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPET :.. . :. :.:::.: :. . . ::. : :..: . .: . :: . NP_689 GHIIHAAI-FICNYAPGGT-LTRRPYEPGIFCTRC--GRRDKCTDFLCSKIKKINMKKMH 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 DEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRY NP_689 NGLDKKNKRLNTSFLWSC 240 250 >>NP_001257325 (OMIM: 610394) GLIPR1-like protein 2 isof (344 aa) initn: 261 init1: 168 opt: 355 Z-score: 387.1 bits: 80.6 E(85289): 8e-15 Smith-Waterman score: 364; 32.8% identity (60.1% similar) in 198 aa overlap (49-234:43-223) 20 30 40 50 60 70 pF1KE0 GSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDK----EEILMLHNKLRGQVQPQA : .: :. .: . :::.:::.: :.. NP_001 AQSLPLAVGGVLKLRLCELWLLLLGSSLNARFLPDEEDVDFINEYVNLHNELRGDVIPRG 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 SNMEYMTWDDELEKSAAAWASQCIWEHG---PTSLLV-----SIGQNLGAHWGRYRSPGF ::...:::: : ..: ::...:.. :. .: .::.:. . . .. NP_001 SNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENMWVGPENEFTASI 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE0 HVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVW ..::. : : :.. : ::: :..: :.:: . :.::::. : :. NP_001 AIRSWHAEKKMYNFENGS---------CSGD-CSNYIQLVWDHSYKVGCAVTPCSKI--- 140 150 160 170 190 200 210 220 230 240 pF1KE0 GEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPET :.. . :. :.:::.: :. . . ::. : :..: . .: . :: NP_001 GHIIHAAI-FICNYAPGGT-LTRRPYEPGIFCTRC--GRRDKCTDFLCSNADRDQATYYR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 DEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRY NP_001 FWYPKWEMPRPVVCDPLCTFILLLRILCFILCVITVLIVQSQFPNILLEQQMIFTPEESE 240 250 260 270 280 290 497 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:53:31 2016 done: Sat Nov 5 21:53:33 2016 Total Scan time: 9.500 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]