FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0010, 770 aa 1>>>pF1KE0010 770 - 770 aa - 770 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.5083+/-0.00106; mu= -6.6664+/- 0.063 mean_var=365.7890+/-74.418, 0's: 0 Z-trim(114.5): 27 B-trim: 0 in 0/53 Lambda= 0.067059 statistics sampled from 15017 (15033) to 15017 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.462), width: 16 Scan time: 4.320 The best scores are: opt bits E(32554) CCDS44613.1 PATL1 gene_id:219988|Hs108|chr11 ( 770) 5188 516.3 7.4e-146 CCDS45253.1 PATL2 gene_id:197135|Hs108|chr15 ( 543) 655 77.6 5.8e-14 CCDS81873.1 PATL2 gene_id:197135|Hs108|chr15 ( 354) 575 69.7 9e-12 >>CCDS44613.1 PATL1 gene_id:219988|Hs108|chr11 (770 aa) initn: 5188 init1: 5188 opt: 5188 Z-score: 2732.1 bits: 516.3 E(32554): 7.4e-146 Smith-Waterman score: 5188; 99.9% identity (100.0% similar) in 770 aa overlap (1-770:1-770) 10 20 30 40 50 60 pF1KE0 MFRYESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MFRYESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 LNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 PNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 HRRLLHQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HRRLLHQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LQSTDPYLDDFYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LQSTDPYLDDFYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 SLGKLTVSSVNNPRKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SLGKLTVSSVNNPRKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 RRYLLSLEEERPALMDDRKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RRYLLSLEEERPALMDDRKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 LPFLSTEQAADILMTTARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPFLSTEQAADILMTTARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 NLPQSAATPALSNPHLTAVLQNKFGLSLLLILLSRGEDLQSSDPATESTQNNQWTEVMFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NLPQSAATPALSNPHLTAVLQNKFGLSLLLILLSRGEDLQSSDPATESTQNNQWTEVMFM 670 680 690 700 710 720 730 740 750 760 770 pF1KE0 ATRELLRIPQAALARPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR ::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS44 ATRELLRIPQAALAKPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR 730 740 750 760 770 >>CCDS45253.1 PATL2 gene_id:197135|Hs108|chr15 (543 aa) initn: 843 init1: 381 opt: 655 Z-score: 364.1 bits: 77.6 E(32554): 5.8e-14 Smith-Waterman score: 944; 34.0% identity (65.5% similar) in 527 aa overlap (246-765:46-539) 220 230 240 250 260 270 pF1KE0 VRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPG : . :.. . : .::... CCDS45 SEEELVSACQLEKEEENEGEEEEEEEDEEDLDPDLDPDLEEEENDLGDPAVLGAVHNTQR 20 30 40 50 60 70 280 290 300 310 320 330 pF1KE0 RMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQH-P- . : ...::..: ::... . .. ..: : : :. . ::.. : :. : CCDS45 ALLSSPGVKAPGMLGMSLASLH---FLWQTLDYLSPIP----FWPTFPSTSSPAQHFGPR 80 90 100 110 120 340 350 360 370 380 390 pF1KE0 -PGPGPHL--QNLRSQAPMFRPDTTHLHPQHRRLLHQRQQQNRSQHRNLNGAGDRGSHRS :.: : : . : : : : :.:::.:.:.: :::..:: : . CCDS45 LPSPDPTLFCSLLTSWPPRFS-HLTQLHPRHQRIL---QQQQHSQ---------TPSPPA 130 140 150 160 170 400 410 420 430 440 450 pF1KE0 SHQDHLRKDPYANLMLQREKDWVSKIQMMQLQSTDPYLDDFYYQNYFEKLEKLSAAEEIQ .. . ::::::: ..::::: :.::.::::. : :::.:::.:..:::: .: ::. CCDS45 KKPWSQQPDPYANLMTRKEKDWVIKVQMVQLQSAKPRLDDYYYQEYYQKLEKKQADEELL 180 190 200 210 220 230 460 470 480 490 500 510 pF1KE0 GDGPKKERTKLITPQVAKLEHAYKPVQFEGSLGKLTVSSVNNPRKMIDAVVTSRSEDDET : . : ::.:: . : : . :..:::::...::. .::. :::: . .:.: CCDS45 GRRNRVESLKLVTPYIPKAEAYESVVRIEGSLGQVAVSTCFSPRRAIDAVPHGTQEQDI- 240 250 260 270 280 290 520 530 540 550 560 570 pF1KE0 KEKQVRDKRRKTLVIIEKTYSLLLDVEDYERRYLLSLEEERPALMDDRKHKICSMYDNLR . . ..: ..: ::: . ::..:. . . : . ....... .....:. CCDS45 --EAASSQRLRVLYRIEKMFLQLLEIEEGWKY-----RPPPPCFSEQQSNQVEKLFQTLK 300 310 320 330 340 580 590 600 610 620 630 pF1KE0 GKLPGQERPSDDHFVQIMCIRKGKRMVARILPFLSTEQAADILMTTARNLPFLIKKDAQD . .. . . : :.:.. .:::: .:::.:::: .::. ::.. ...::.:...:. : CCDS45 TQEQNNLEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAITHHLPLLVRRDVAD 350 360 370 380 390 400 640 650 660 670 680 690 pF1KE0 EVLPCLLSPFSLLLYHLPSVSITSLLRQLMNLPQSAATPALSNPHLTAVLQNKFGLSLLL ..: :..:.. . :: .. ::. :..: . :. :. .:.::::.::.::: CCDS45 QALQMLFKPLGKCISHL---TLHELLQGLQGL--TLLPPGSSERPVTVVLQNQFGISLLY 410 420 430 440 450 460 700 710 720 730 740 pF1KE0 ILLSRGEDLQSSDPATE--STQNNQWTEVMFMATRELLRIPQAALARPISIPTNLVSLFS :::.::.: : . : ..... ::... . . :. ..: :.::.:...:.::. :: CCDS45 ALLSHGEQLVSLHSSLEEPNSDHTAWTDMVVLIAWEIAQMPTASLAEPLAFPSNLLPLFC 470 480 490 500 510 520 750 760 770 pF1KE0 RYVDRQKLNLLETKLQLVQGIR ..::.: .. ::..... CCDS45 HHVDKQLVQQLEARMEFAWIY 530 540 >>CCDS81873.1 PATL2 gene_id:197135|Hs108|chr15 (354 aa) initn: 744 init1: 338 opt: 575 Z-score: 324.8 bits: 69.7 E(32554): 9e-12 Smith-Waterman score: 794; 36.4% identity (71.3% similar) in 363 aa overlap (405-765:1-350) 380 390 400 410 420 430 pF1KE0 QHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQLQSTDPYLDDFYYQ : ..::::: :.::.::::. : :::.::: CCDS81 MTRKEKDWVIKVQMVQLQSAKPRLDDYYYQ 10 20 30 440 450 460 470 480 490 pF1KE0 NYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEGSLGKLTVSSVNNPR .:..:::: .: ::. : . : ::.:: . : : . :..:::::...::. .:: CCDS81 EYYQKLEKKQADEELLGRRNRVESLKLVTPYIPKAEAYESVVRIEGSLGQVAVSTCFSPR 40 50 60 70 80 90 500 510 520 530 540 550 pF1KE0 KMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYERRYLLSLEEERPAL . :::: . .:.: . . ..: ..: ::: . ::..:. . . : . CCDS81 RAIDAVPHGTQEQDI---EAASSQRLRVLYRIEKMFLQLLEIEEGWKY-----RPPPPCF 100 110 120 130 140 560 570 580 590 600 610 pF1KE0 MDDRKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARILPFLSTEQAADILM ....... .....:. . .. . . : :.:.. .:::: .:::.:::: .::. ::. CCDS81 SEQQSNQVEKLFQTLKTQEQNNLEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILL 150 160 170 180 190 200 620 630 640 650 660 670 pF1KE0 TTARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLMNLPQSAATPALSNP . ...::.:...:. :..: :..:.. . :: .. ::. :..: . :. :. CCDS81 AITHHLPLLVRRDVADQALQMLFKPLGKCISHL---TLHELLQGLQGL--TLLPPGSSER 210 220 230 240 250 680 690 700 710 720 730 pF1KE0 HLTAVLQNKFGLSLLLILLSRGEDLQSSDPATE--STQNNQWTEVMFMATRELLRIPQAA .:.::::.::.::: :::.::.: : . : ..... ::... . . :. ..: :. CCDS81 PVTVVLQNQFGISLLYALLSHGEQLVSLHSSLEEPNSDHTAWTDMVVLIAWEIAQMPTAS 260 270 280 290 300 310 740 750 760 770 pF1KE0 LARPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR ::.:...:.::. :: ..::.: .. ::..... CCDS81 LAEPLAFPSNLLPLFCHHVDKQLVQQLEARMEFAWIY 320 330 340 350 770 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:28:22 2016 done: Fri Nov 4 08:28:22 2016 Total Scan time: 4.320 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]