FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0011, 813 aa 1>>>pF1KE0011 813 - 813 aa - 813 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4055+/-0.00133; mu= 2.5627+/- 0.080 mean_var=239.1727+/-49.244, 0's: 0 Z-trim(107.7): 66 B-trim: 56 in 1/51 Lambda= 0.082931 statistics sampled from 9718 (9762) to 9718 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.3), width: 16 Scan time: 4.060 The best scores are: opt bits E(32554) CCDS4111.1 MCC gene_id:4163|Hs108|chr5 ( 829) 5053 618.6 1.3e-176 CCDS43351.1 MCC gene_id:4163|Hs108|chr5 (1019) 5053 618.7 1.5e-176 >>CCDS4111.1 MCC gene_id:4163|Hs108|chr5 (829 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3284.2 bits: 618.6 E(32554): 1.3e-176 Smith-Waterman score: 5053; 99.6% identity (100.0% similar) in 810 aa overlap (4-813:20-829) 10 20 30 40 pF1KE0 MGLLHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQ ::::::::::::::::::::::::::::::::::::::::: CCDS41 MNSGVAMKYGNDSSAELSELHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE0 SHLMREHEDVRERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQS ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 QHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE0 CSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLRE :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 CSLSVAEVDKHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLRE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE0 ENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 TNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSV 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE0 AEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KE0 LEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAA 430 440 450 460 470 480 470 480 490 500 510 520 pF1KE0 GVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMRLDGSCGGAFAVAGCSVQPWES ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: CCDS41 GVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAVAGCSVQPWES 490 500 510 520 530 540 530 540 550 560 570 580 pF1KE0 LSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSY 550 560 570 580 590 600 590 600 610 620 630 640 pF1KE0 DVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAY 610 620 630 640 650 660 650 660 670 680 690 700 pF1KE0 LVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAELRTTCSENELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAELRTTCSENELA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KE0 AEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAK 730 740 750 760 770 780 770 780 790 800 810 pF1KE0 KKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL 790 800 810 820 >>CCDS43351.1 MCC gene_id:4163|Hs108|chr5 (1019 aa) initn: 5053 init1: 5053 opt: 5053 Z-score: 3282.9 bits: 618.7 E(32554): 1.5e-176 Smith-Waterman score: 5053; 99.6% identity (100.0% similar) in 810 aa overlap (4-813:210-1019) 10 20 30 pF1KE0 MGLLHSAALASLKGDIVELNKRLQQTERERDLL :::::::::::::::::::::::::::::: CCDS43 HQQAALHKLLTQSPHIGNSVGGSYLELANTLHSAALASLKGDIVELNKRLQQTERERDLL 180 190 200 210 220 230 40 50 60 70 80 90 pF1KE0 EKKLAKAQCEQSHLMREHEDVRERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDE :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS43 EKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDE 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE0 YSELRSELSQSQHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YSELRSELSQSQHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGL 300 310 320 330 340 350 160 170 180 190 200 210 pF1KE0 ENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERS ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS43 ENVVCGRKKSSCSLSVAEVDKHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERS 360 370 380 390 400 410 220 230 240 250 260 270 pF1KE0 RWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQA 420 430 440 450 460 470 280 290 300 310 320 330 pF1KE0 TGPSSPGRLTSTNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TGPSSPGRLTSTNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGS 480 490 500 510 520 530 340 350 360 370 380 390 pF1KE0 EISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEH 540 550 560 570 580 590 400 410 420 430 440 450 pF1KE0 LKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESE 600 610 620 630 640 650 460 470 480 490 500 510 pF1KE0 QSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMRLDGSCGGAFA :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: CCDS43 QSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFA 660 670 680 690 700 710 520 530 540 550 560 570 pF1KE0 VAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLE 720 730 740 750 760 770 580 590 600 610 620 630 pF1KE0 LESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELK 780 790 800 810 820 830 640 650 660 670 680 690 pF1KE0 LSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAE 840 850 860 870 880 890 700 710 720 730 740 750 pF1KE0 LRTTCSENELAAEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LRTTCSENELAAEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRAN 900 910 920 930 940 950 760 770 780 790 800 810 pF1KE0 SNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL 960 970 980 990 1000 1010 813 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 08:27:05 2016 done: Fri Nov 4 08:27:06 2016 Total Scan time: 4.060 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]