FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0013, 723 aa 1>>>pF1KE0013 723 - 723 aa - 723 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9667+/-0.000517; mu= 22.1352+/- 0.032 mean_var=71.4785+/-14.889, 0's: 0 Z-trim(106.7): 53 B-trim: 0 in 0/50 Lambda= 0.151700 statistics sampled from 14744 (14792) to 14744 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.504), E-opt: 0.2 (0.173), width: 16 Scan time: 10.300 The best scores are: opt bits E(85289) NP_861452 (OMIM: 613895) probable C-mannosyltransf ( 723) 4772 1054.7 0 XP_005250951 (OMIM: 613895) PREDICTED: probable C- ( 797) 4747 1049.3 0 XP_016868843 (OMIM: 613895) PREDICTED: probable C- ( 618) 4078 902.8 0 XP_005250952 (OMIM: 613895) PREDICTED: probable C- ( 618) 4078 902.8 0 XP_016868841 (OMIM: 613895) PREDICTED: probable C- ( 651) 4013 888.6 0 XP_016868844 (OMIM: 613895) PREDICTED: probable C- ( 587) 3885 860.5 0 XP_016868845 (OMIM: 613895) PREDICTED: probable C- ( 576) 3168 703.6 5.5e-202 XP_011515286 (OMIM: 613895) PREDICTED: probable C- ( 681) 3168 703.7 6.3e-202 XP_016868846 (OMIM: 613895) PREDICTED: probable C- ( 574) 2608 581.1 4.3e-165 XP_016868840 (OMIM: 613895) PREDICTED: probable C- ( 679) 2608 581.1 4.9e-165 XP_016868842 (OMIM: 613895) PREDICTED: probable C- ( 646) 2420 540.0 1.1e-152 XP_011515285 (OMIM: 613895) PREDICTED: probable C- ( 690) 2403 536.3 1.6e-151 XP_011524828 (OMIM: 613894) PREDICTED: probable C- ( 716) 2011 450.5 1.1e-125 NP_997208 (OMIM: 613894) probable C-mannosyltransf ( 716) 2011 450.5 1.1e-125 NP_001166245 (OMIM: 613894) probable C-mannosyltra ( 716) 2011 450.5 1.1e-125 XP_006723108 (OMIM: 613894) PREDICTED: probable C- ( 520) 1427 322.5 2.6e-87 XP_016881856 (OMIM: 613894) PREDICTED: probable C- ( 453) 1180 268.4 4.3e-71 XP_016881855 (OMIM: 613894) PREDICTED: probable C- ( 682) 976 223.9 1.6e-57 XP_016874679 (OMIM: 613893,613958) PREDICTED: prob ( 720) 349 86.7 3.4e-16 XP_016874685 (OMIM: 613893,613958) PREDICTED: prob ( 601) 346 86.0 4.7e-16 XP_016874687 (OMIM: 613893,613958) PREDICTED: prob ( 570) 345 85.8 5.3e-16 NP_056098 (OMIM: 613892) probable C-mannosyltransf ( 675) 326 81.7 1.1e-14 XP_011513547 (OMIM: 613892) PREDICTED: probable C- ( 748) 322 80.8 2.1e-14 XP_016874689 (OMIM: 613893,613958) PREDICTED: prob ( 449) 316 79.3 3.6e-14 NP_776173 (OMIM: 613893,613958) probable C-mannosy ( 758) 301 76.2 5.2e-13 XP_016874682 (OMIM: 613893,613958) PREDICTED: prob ( 657) 293 74.4 1.6e-12 XP_006719415 (OMIM: 613893,613958) PREDICTED: prob ( 615) 251 65.2 8.8e-10 XP_016874684 (OMIM: 613893,613958) PREDICTED: prob ( 615) 251 65.2 8.8e-10 XP_016874683 (OMIM: 613893,613958) PREDICTED: prob ( 637) 237 62.2 7.5e-09 XP_016874677 (OMIM: 613893,613958) PREDICTED: prob ( 762) 237 62.2 8.6e-09 XP_011536520 (OMIM: 613893,613958) PREDICTED: prob ( 421) 220 58.3 7.3e-08 XP_016874694 (OMIM: 613893,613958) PREDICTED: prob ( 423) 220 58.3 7.3e-08 XP_016874693 (OMIM: 613893,613958) PREDICTED: prob ( 423) 220 58.3 7.3e-08 XP_016874692 (OMIM: 613893,613958) PREDICTED: prob ( 423) 220 58.3 7.3e-08 XP_016874691 (OMIM: 613893,613958) PREDICTED: prob ( 443) 220 58.3 7.5e-08 XP_016874690 (OMIM: 613893,613958) PREDICTED: prob ( 443) 220 58.3 7.5e-08 XP_016874688 (OMIM: 613893,613958) PREDICTED: prob ( 517) 220 58.4 8.5e-08 XP_016874686 (OMIM: 613893,613958) PREDICTED: prob ( 587) 220 58.4 9.3e-08 XP_011536517 (OMIM: 613893,613958) PREDICTED: prob ( 587) 220 58.4 9.3e-08 XP_016874681 (OMIM: 613893,613958) PREDICTED: prob ( 708) 220 58.5 1.1e-07 XP_016874680 (OMIM: 613893,613958) PREDICTED: prob ( 712) 220 58.5 1.1e-07 XP_016874678 (OMIM: 613893,613958) PREDICTED: prob ( 742) 220 58.5 1.1e-07 XP_011513548 (OMIM: 613892) PREDICTED: probable C- ( 719) 217 57.8 1.7e-07 >>NP_861452 (OMIM: 613895) probable C-mannosyltransferas (723 aa) initn: 4772 init1: 4772 opt: 4772 Z-score: 5643.1 bits: 1054.7 E(85289): 0 Smith-Waterman score: 4772; 99.9% identity (100.0% similar) in 723 aa overlap (1-723:1-723) 10 20 30 40 50 60 pF1KE0 MADEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 MAEEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_861 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS 670 680 690 700 710 720 pF1KE0 FQS ::: NP_861 FQS >>XP_005250951 (OMIM: 613895) PREDICTED: probable C-mann (797 aa) initn: 4747 init1: 4747 opt: 4747 Z-score: 5613.0 bits: 1049.3 E(85289): 0 Smith-Waterman score: 4747; 99.9% identity (100.0% similar) in 719 aa overlap (5-723:79-797) 10 20 30 pF1KE0 MADEEGPPVELRQRKKPKSSENKESAKEEKISDI .::::::::::::::::::::::::::::: XP_005 GRSAAPRRGLRRNSGERSKWPEVLSAELGSKGPPVELRQRKKPKSSENKESAKEEKISDI 50 60 70 80 90 100 40 50 60 70 80 90 pF1KE0 PIPERAPKHVLFQRFAKIFIGCLAAVTSGMMYALYLSAYHERKFWFSNRQELEREITFQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIPERAPKHVLFQRFAKIFIGCLAAVTSGMMYALYLSAYHERKFWFSNRQELEREITFQG 110 120 130 140 150 160 100 110 120 130 140 150 pF1KE0 DSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASILYQATGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASILYQATGS 170 180 190 200 210 220 160 170 180 190 200 210 pF1KE0 NEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSI 230 240 250 260 270 280 220 230 240 250 260 270 pF1KE0 PLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQA 290 300 310 320 330 340 280 290 300 310 320 330 pF1KE0 ISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQ 350 360 370 380 390 400 340 350 360 370 380 390 pF1KE0 LNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNF 410 420 430 440 450 460 400 410 420 430 440 450 pF1KE0 TMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLSMLQVIFRRINGKSLKETVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLSMLQVIFRRINGKSLKETVT 470 480 490 500 510 520 460 470 480 490 500 510 pF1KE0 LEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKW 530 540 550 560 570 580 520 530 540 550 560 570 pF1KE0 LRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQ 590 600 610 620 630 640 580 590 600 610 620 630 pF1KE0 APVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILT 650 660 670 680 690 700 640 650 660 670 680 690 pF1KE0 SYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINY 710 720 730 740 750 760 700 710 720 pF1KE0 SPYVNYFTRVYWNRSYFVYKINTVISFQS ::::::::::::::::::::::::::::: XP_005 SPYVNYFTRVYWNRSYFVYKINTVISFQS 770 780 790 >>XP_016868843 (OMIM: 613895) PREDICTED: probable C-mann (618 aa) initn: 4078 init1: 4078 opt: 4078 Z-score: 4823.2 bits: 902.8 E(85289): 0 Smith-Waterman score: 4078; 100.0% identity (100.0% similar) in 618 aa overlap (106-723:1-618) 80 90 100 110 120 130 pF1KE0 RKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQ :::::::::::::::::::::::::::::: XP_016 MLKAPSFERGVYELTHNNKTVSLKTINAVQ 10 20 30 140 150 160 170 180 190 pF1KE0 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE0 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE0 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE0 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE0 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME 400 410 420 430 440 450 560 570 580 590 600 610 pF1KE0 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE 460 470 480 490 500 510 620 630 640 650 660 670 pF1KE0 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG 520 530 540 550 560 570 680 690 700 710 720 pF1KE0 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS 580 590 600 610 >>XP_005250952 (OMIM: 613895) PREDICTED: probable C-mann (618 aa) initn: 4078 init1: 4078 opt: 4078 Z-score: 4823.2 bits: 902.8 E(85289): 0 Smith-Waterman score: 4078; 100.0% identity (100.0% similar) in 618 aa overlap (106-723:1-618) 80 90 100 110 120 130 pF1KE0 RKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQ :::::::::::::::::::::::::::::: XP_005 MLKAPSFERGVYELTHNNKTVSLKTINAVQ 10 20 30 140 150 160 170 180 190 pF1KE0 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE0 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE0 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE0 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE0 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME 400 410 420 430 440 450 560 570 580 590 600 610 pF1KE0 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE 460 470 480 490 500 510 620 630 640 650 660 670 pF1KE0 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG 520 530 540 550 560 570 680 690 700 710 720 pF1KE0 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS 580 590 600 610 >>XP_016868841 (OMIM: 613895) PREDICTED: probable C-mann (651 aa) initn: 4011 init1: 4011 opt: 4013 Z-score: 4746.0 bits: 888.6 E(85289): 0 Smith-Waterman score: 4127; 89.8% identity (90.0% similar) in 723 aa overlap (1-723:1-651) 10 20 30 40 50 60 pF1KE0 MADEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV ::.:::::::::::::::::::::::::::::::::::::::.: XP_016 MAEEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKRV---------------- 10 20 30 40 70 80 90 100 110 120 pF1KE0 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT :::: XP_016 --------------------------------------------------------YELT 130 140 150 160 170 180 pF1KE0 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF 50 60 70 80 90 100 190 200 210 220 230 240 pF1KE0 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL 110 120 130 140 150 160 250 260 270 280 290 300 pF1KE0 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF 170 180 190 200 210 220 310 320 330 340 350 360 pF1KE0 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI 230 240 250 260 270 280 370 380 390 400 410 420 pF1KE0 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS 290 300 310 320 330 340 430 440 450 460 470 480 pF1KE0 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA 350 360 370 380 390 400 490 500 510 520 530 540 pF1KE0 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS 410 420 430 440 450 460 550 560 570 580 590 600 pF1KE0 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT 470 480 490 500 510 520 610 620 630 640 650 660 pF1KE0 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK 530 540 550 560 570 580 670 680 690 700 710 720 pF1KE0 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS 590 600 610 620 630 640 pF1KE0 FQS ::: XP_016 FQS 650 >>XP_016868844 (OMIM: 613895) PREDICTED: probable C-mann (587 aa) initn: 3885 init1: 3885 opt: 3885 Z-score: 4595.2 bits: 860.5 E(85289): 0 Smith-Waterman score: 3885; 100.0% identity (100.0% similar) in 587 aa overlap (137-723:1-587) 110 120 130 140 150 160 pF1KE0 LKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIG :::::::::::::::::::::::::::::: XP_016 MSLYPELIASILYQATGSNEIIEPVYFYIG 10 20 30 170 180 190 200 210 220 pF1KE0 IVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFA 40 50 60 70 80 90 230 240 250 260 270 280 pF1KE0 CQIAALTGYLKSNLNTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQIAALTGYLKSNLNTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVE 100 110 120 130 140 150 290 300 310 320 330 340 pF1KE0 QSDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKI 160 170 180 190 200 210 350 360 370 380 390 400 pF1KE0 IKVINFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKVINFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQ 220 230 240 250 260 270 410 420 430 440 450 460 pF1KE0 APSQDFFLRLTQSSLLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APSQDFFLRLTQSSLLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEI 280 290 300 310 320 330 470 480 490 500 510 520 pF1KE0 IYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLA 340 350 360 370 380 390 530 540 550 560 570 580 pF1KE0 LILSMAVPTIIGLSLWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LILSMAVPTIIGLSLWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQ 400 410 420 430 440 450 590 600 610 620 630 640 pF1KE0 LMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDA 460 470 480 490 500 510 650 660 670 680 690 700 pF1KE0 ICNEVGPMRGCRVKDLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICNEVGPMRGCRVKDLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYW 520 530 540 550 560 570 710 720 pF1KE0 NRSYFVYKINTVISFQS ::::::::::::::::: XP_016 NRSYFVYKINTVISFQS 580 >>XP_016868845 (OMIM: 613895) PREDICTED: probable C-mann (576 aa) initn: 3168 init1: 3168 opt: 3168 Z-score: 3747.3 bits: 703.6 E(85289): 5.5e-202 Smith-Waterman score: 3704; 93.2% identity (93.2% similar) in 618 aa overlap (106-723:1-576) 80 90 100 110 120 130 pF1KE0 RKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQ :::::::::::::::::::::::::::::: XP_016 MLKAPSFERGVYELTHNNKTVSLKTINAVQ 10 20 30 140 150 160 170 180 190 pF1KE0 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS ::::::::: ::::::::: XP_016 TVAWFVINR------------------------------------------FCYLLMSAS 100 260 270 280 290 300 310 pF1KE0 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL 110 120 130 140 150 160 320 330 340 350 360 370 pF1KE0 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN 170 180 190 200 210 220 380 390 400 410 420 430 pF1KE0 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS 230 240 250 260 270 280 440 450 460 470 480 490 pF1KE0 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC 290 300 310 320 330 340 500 510 520 530 540 550 pF1KE0 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME 350 360 370 380 390 400 560 570 580 590 600 610 pF1KE0 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE 410 420 430 440 450 460 620 630 640 650 660 670 pF1KE0 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG 470 480 490 500 510 520 680 690 700 710 720 pF1KE0 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS 530 540 550 560 570 >>XP_011515286 (OMIM: 613895) PREDICTED: probable C-mann (681 aa) initn: 3168 init1: 3168 opt: 3168 Z-score: 3746.3 bits: 703.7 E(85289): 6.3e-202 Smith-Waterman score: 4398; 94.1% identity (94.2% similar) in 723 aa overlap (1-723:1-681) 10 20 30 40 50 60 pF1KE0 MADEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL :::::::::::::::::::::::: XP_011 VTSWLMSGTWLAGMLTVAWFVINR------------------------------------ 190 200 250 260 270 280 290 300 pF1KE0 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ------FCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF 210 220 230 240 250 310 320 330 340 350 360 pF1KE0 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI 260 270 280 290 300 310 370 380 390 400 410 420 pF1KE0 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS 320 330 340 350 360 370 430 440 450 460 470 480 pF1KE0 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA 380 390 400 410 420 430 490 500 510 520 530 540 pF1KE0 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS 440 450 460 470 480 490 550 560 570 580 590 600 pF1KE0 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT 500 510 520 530 540 550 610 620 630 640 650 660 pF1KE0 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK 560 570 580 590 600 610 670 680 690 700 710 720 pF1KE0 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS 620 630 640 650 660 670 pF1KE0 FQS ::: XP_011 FQS 680 >>XP_016868846 (OMIM: 613895) PREDICTED: probable C-mann (574 aa) initn: 2598 init1: 2598 opt: 2608 Z-score: 3084.9 bits: 581.1 E(85289): 4.3e-165 Smith-Waterman score: 3706; 92.9% identity (92.9% similar) in 618 aa overlap (106-723:1-574) 80 90 100 110 120 130 pF1KE0 RKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQ :::::::::::::::::::::::::::::: XP_016 MLKAPSFERGVYELTHNNKTVSLKTINAVQ 10 20 30 140 150 160 170 180 190 pF1KE0 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGML 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE0 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNLNTYGERFCYLLMSAS 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE0 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPAL ::::::::::::::::::::::::::::::::::: XP_016 TYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDK------------------------- 160 170 180 320 330 340 350 360 370 pF1KE0 LVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN ::::::::::::::::::::::::::::::::::::::::: XP_016 -------------------LNVKKGSFVAKIIKVINFYLVCTLTITLNIIMKMFVPHKEN 190 200 210 220 380 390 400 410 420 430 pF1KE0 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICFLS 230 240 250 260 270 280 440 450 460 470 480 490 pF1KE0 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVC 290 300 310 320 330 340 500 510 520 530 540 550 pF1KE0 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLMTELME 350 360 370 380 390 400 560 570 580 590 600 610 pF1KE0 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE 410 420 430 440 450 460 620 630 640 650 660 670 pF1KE0 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEG 470 480 490 500 510 520 680 690 700 710 720 pF1KE0 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVISFQS 530 540 550 560 570 >>XP_016868840 (OMIM: 613895) PREDICTED: probable C-mann (679 aa) initn: 2598 init1: 2598 opt: 2608 Z-score: 3083.9 bits: 581.1 E(85289): 4.9e-165 Smith-Waterman score: 4400; 93.8% identity (93.9% similar) in 723 aa overlap (1-723:1-679) 10 20 30 40 50 60 pF1KE0 MADEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAEEEGPPVELRQRKKPKSSENKESAKEEKISDIPIPERAPKHVLFQRFAKIFIGCLAAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNNKTVSLKTINAVQQMSLYPELIASILYQATGSNEIIEPVYFYIGIVFGLQGIYVTALF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIF :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDK---------- 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 SLFLGYLLQFENPALLVSPLLSLVAALMLAKCLQLNVKKGSFVAKIIKVINFYLVCTLTI :::::::::::::::::::::::::: XP_016 ----------------------------------LNVKKGSFVAKIIKVINFYLVCTLTI 300 310 370 380 390 400 410 420 pF1KE0 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQAPSQDFFLRLTQSS 320 330 340 350 360 370 430 440 450 460 470 480 pF1KE0 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPFYILVLIICFLSMLQVIFRRINGKSLKETVTLEDGRIGERPEIIYHVIHTILLGSLA 380 390 400 410 420 430 490 500 510 520 530 540 pF1KE0 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWLRLRTVHPILLALILSMAVPTIIGLS 440 450 460 470 480 490 550 560 570 580 590 600 pF1KE0 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWKEFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVT 500 510 520 530 540 550 610 620 630 640 650 660 pF1KE0 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVK 560 570 580 590 600 610 670 680 690 700 710 720 pF1KE0 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLDIANGHMVCEEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKINTVIS 620 630 640 650 660 670 pF1KE0 FQS ::: XP_016 FQS 723 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 22:10:44 2016 done: Sat Nov 5 22:10:45 2016 Total Scan time: 10.300 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]