FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0015, 651 aa 1>>>pF1KE0015 651 - 651 aa - 651 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6974+/-0.000377; mu= 8.0198+/- 0.023 mean_var=137.2972+/-27.365, 0's: 0 Z-trim(117.0): 39 B-trim: 35 in 1/50 Lambda= 0.109457 statistics sampled from 28587 (28626) to 28587 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.336), width: 16 Scan time: 8.840 The best scores are: opt bits E(85289) NP_001139543 (OMIM: 614392) tudor domain-containin ( 651) 4389 705.0 2.1e-202 NP_110421 (OMIM: 614392) tudor domain-containing p ( 651) 4389 705.0 2.1e-202 XP_016876266 (OMIM: 614392) PREDICTED: tudor domai ( 744) 4389 705.1 2.3e-202 NP_001139542 (OMIM: 614392) tudor domain-containin ( 744) 4389 705.1 2.3e-202 XP_011533549 (OMIM: 614392) PREDICTED: tudor domai ( 715) 4134 664.8 3e-190 XP_005266617 (OMIM: 614392) PREDICTED: tudor domai ( 716) 4134 664.8 3e-190 XP_005266613 (OMIM: 614392) PREDICTED: tudor domai ( 809) 4134 664.8 3.3e-190 XP_011533551 (OMIM: 614392) PREDICTED: tudor domai ( 341) 1870 307.1 6.7e-83 >>NP_001139543 (OMIM: 614392) tudor domain-containing pr (651 aa) initn: 4389 init1: 4389 opt: 4389 Z-score: 3754.8 bits: 705.0 E(85289): 2.1e-202 Smith-Waterman score: 4389; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:1-651) 10 20 30 40 50 60 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 LLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN 610 620 630 640 650 >>NP_110421 (OMIM: 614392) tudor domain-containing prote (651 aa) initn: 4389 init1: 4389 opt: 4389 Z-score: 3754.8 bits: 705.0 E(85289): 2.1e-202 Smith-Waterman score: 4389; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:1-651) 10 20 30 40 50 60 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 LLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 LLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN 610 620 630 640 650 >>XP_016876266 (OMIM: 614392) PREDICTED: tudor domain-co (744 aa) initn: 4389 init1: 4389 opt: 4389 Z-score: 3753.9 bits: 705.1 E(85289): 2.3e-202 Smith-Waterman score: 4389; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:94-744) 10 20 30 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPP :::::::::::::::::::::::::::::: XP_016 KLEGPCVLQIQKIRNVAAPKDNEESQAAPRMLRLQMTDGHISCTAVEFSYMSKISLNTPP 70 80 90 100 110 120 40 50 60 70 80 90 pF1KE0 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP 130 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF 190 200 210 220 230 240 160 170 180 190 200 210 pF1KE0 GGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKE 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 ASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAP 310 320 330 340 350 360 280 290 300 310 320 330 pF1KE0 STLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRN 370 380 390 400 410 420 340 350 360 370 380 390 pF1KE0 EKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDT 430 440 450 460 470 480 400 410 420 430 440 450 pF1KE0 SYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIP 490 500 510 520 530 540 460 470 480 490 500 510 pF1KE0 DYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPI 550 560 570 580 590 600 520 530 540 550 560 570 pF1KE0 KPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDN 610 620 630 640 650 660 580 590 600 610 620 630 pF1KE0 KFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWEEEGTYDQTLEFRRGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWEEEGTYDQTLEFRRGGD 670 680 690 700 710 720 640 650 pF1KE0 GQPRRSTRPTQQFYQPPRARN ::::::::::::::::::::: XP_016 GQPRRSTRPTQQFYQPPRARN 730 740 >>NP_001139542 (OMIM: 614392) tudor domain-containing pr (744 aa) initn: 4389 init1: 4389 opt: 4389 Z-score: 3753.9 bits: 705.1 E(85289): 2.3e-202 Smith-Waterman score: 4389; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:94-744) 10 20 30 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPP :::::::::::::::::::::::::::::: NP_001 KLEGPCVLQIQKIRNVAAPKDNEESQAAPRMLRLQMTDGHISCTAVEFSYMSKISLNTPP 70 80 90 100 110 120 40 50 60 70 80 90 pF1KE0 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP 130 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF 190 200 210 220 230 240 160 170 180 190 200 210 pF1KE0 GGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKE 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 ASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAP 310 320 330 340 350 360 280 290 300 310 320 330 pF1KE0 STLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRN 370 380 390 400 410 420 340 350 360 370 380 390 pF1KE0 EKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDT 430 440 450 460 470 480 400 410 420 430 440 450 pF1KE0 SYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIP 490 500 510 520 530 540 460 470 480 490 500 510 pF1KE0 DYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPI 550 560 570 580 590 600 520 530 540 550 560 570 pF1KE0 KPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDN 610 620 630 640 650 660 580 590 600 610 620 630 pF1KE0 KFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWEEEGTYDQTLEFRRGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWEEEGTYDQTLEFRRGGD 670 680 690 700 710 720 640 650 pF1KE0 GQPRRSTRPTQQFYQPPRARN ::::::::::::::::::::: NP_001 GQPRRSTRPTQQFYQPPRARN 730 740 >>XP_011533549 (OMIM: 614392) PREDICTED: tudor domain-co (715 aa) initn: 4119 init1: 4119 opt: 4134 Z-score: 3536.6 bits: 664.8 E(85289): 3e-190 Smith-Waterman score: 4134; 98.1% identity (98.4% similar) in 632 aa overlap (1-632:1-630) 10 20 30 40 50 60 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 LLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN ::::::::::::: : . ::: : : :. XP_011 LLSNIKPIQTEAWA--GKHFQTLCFILKGFGEKGSLSSRGAGNAQEESEDLGSSPGSATY 610 620 630 640 650 XP_011 YLCDFGRKKAPTIKLWSSVGEVMASQDDPLGQPNSFTNHPGLGTNRKRLFVKKRASD 660 670 680 690 700 710 >>XP_005266617 (OMIM: 614392) PREDICTED: tudor domain-co (716 aa) initn: 4119 init1: 4119 opt: 4134 Z-score: 3536.6 bits: 664.8 E(85289): 3e-190 Smith-Waterman score: 4134; 98.1% identity (98.4% similar) in 632 aa overlap (1-632:1-630) 10 20 30 40 50 60 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEV 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 LLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN ::::::::::::: : . ::: : : :. XP_005 LLSNIKPIQTEAWA--GKHFQTLCFILKGFGEKGSLSSRGAGNAQEESEDLGSSPGSATY 610 620 630 640 650 XP_005 YLCDFGRKKAPTIKLWSSVGEVMASQDDPLGQPNSFTNHPGLGTNRKSRLFVKKRASD 660 670 680 690 700 710 >>XP_005266613 (OMIM: 614392) PREDICTED: tudor domain-co (809 aa) initn: 4119 init1: 4119 opt: 4134 Z-score: 3535.8 bits: 664.8 E(85289): 3.3e-190 Smith-Waterman score: 4134; 98.1% identity (98.4% similar) in 632 aa overlap (1-632:94-723) 10 20 30 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPP :::::::::::::::::::::::::::::: XP_005 KLEGPCVLQIQKIRNVAAPKDNEESQAAPRMLRLQMTDGHISCTAVEFSYMSKISLNTPP 70 80 90 100 110 120 40 50 60 70 80 90 pF1KE0 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP 130 140 150 160 170 180 100 110 120 130 140 150 pF1KE0 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF 190 200 210 220 230 240 160 170 180 190 200 210 pF1KE0 GGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKE 250 260 270 280 290 300 220 230 240 250 260 270 pF1KE0 ASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAP 310 320 330 340 350 360 280 290 300 310 320 330 pF1KE0 STLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRN 370 380 390 400 410 420 340 350 360 370 380 390 pF1KE0 EKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDT 430 440 450 460 470 480 400 410 420 430 440 450 pF1KE0 SYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIP 490 500 510 520 530 540 460 470 480 490 500 510 pF1KE0 DYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPI 550 560 570 580 590 600 520 530 540 550 560 570 pF1KE0 KPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDN 610 620 630 640 650 660 580 590 600 610 620 630 pF1KE0 KFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWEEEGTYDQTLEFRRGGD ::::::::::::::::::::::::::::::::::::::::::: : . ::: : : XP_005 KFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWA--GKHFQTLCFILKGF 670 680 690 700 710 720 640 650 pF1KE0 GQPRRSTRPTQQFYQPPRARN :. XP_005 GEKGSLSSRGAGNAQEESEDLGSSPGSATYYLCDFGRKKAPTIKLWSSVGEVMASQDDPL 730 740 750 760 770 780 >>XP_011533551 (OMIM: 614392) PREDICTED: tudor domain-co (341 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 1609.3 bits: 307.1 E(85289): 6.7e-83 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KE0 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQ ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEVNFLATEGTVSPK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSER XP_011 MSVEALFGSVTLGKYKNNYSCMLIMMYDKGNKTHTPKTNET 310 320 330 340 651 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 22:06:06 2016 done: Sat Nov 5 22:06:07 2016 Total Scan time: 8.840 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]