Result of FASTA (omim) for
pF1KE0019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0019, 592 aa
1>>>pF1KE0019 592 - 592 aa - 592 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5504+/-0.000425; mu= 20.1991+/- 0.027
mean_var=150.0248+/-32.155, 0's: 0 Z-trim(115.1): 114 B-trim: 1305 in 1/51
Lambda= 0.104711
statistics sampled from 25169 (25299) to 25169 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.297), width: 16
Scan time: 10.360
The best scores are: opt bits E(85289)
NP_001107033 (OMIM: 616015) E3 ubiquitin-protein l ( 592) 4112 633.8 4.9e-181
XP_016864878 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 598) 4090 630.5 4.9e-180
XP_016864877 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 598) 4090 630.5 4.9e-180
XP_016864872 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 598) 4090 630.5 4.9e-180
XP_016864874 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 666) 3819 589.6 1.1e-167
XP_016864873 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 672) 3797 586.3 1.1e-166
NP_001310221 (OMIM: 616015) E3 ubiquitin-protein l ( 530) 3614 558.5 2e-158
XP_016864875 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 543) 3584 554.0 4.7e-157
XP_016864876 (OMIM: 616015) PREDICTED: E3 ubiquiti ( 505) 3305 511.8 2.2e-144
NP_848627 (OMIM: 616015) E3 ubiquitin-protein liga ( 416) 2770 430.8 4.2e-120
NP_001310220 (OMIM: 616015) E3 ubiquitin-protein l ( 96) 549 94.4 1.8e-19
>>NP_001107033 (OMIM: 616015) E3 ubiquitin-protein ligas (592 aa)
initn: 4112 init1: 4112 opt: 4112 Z-score: 3371.2 bits: 633.8 E(85289): 4.9e-181
Smith-Waterman score: 4112; 99.8% identity (99.8% similar) in 592 aa overlap (1-592:1-592)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMTLNNEMSTDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMTLNNEMSTDED
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCRTIISRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCRTIISRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 FFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAPVTRRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAPVTRRQF
490 500 510 520 530 540
550 560 570 580 590
pF1KE0 PHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
550 560 570 580 590
>>XP_016864878 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (598 aa)
initn: 4098 init1: 2770 opt: 4090 Z-score: 3353.2 bits: 630.5 E(85289): 4.9e-180
Smith-Waterman score: 4090; 98.8% identity (98.8% similar) in 598 aa overlap (1-592:1-598)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHM------TLNNE
::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMFSYVLQTLNNE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE0 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
550 560 570 580 590
>>XP_016864877 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (598 aa)
initn: 4098 init1: 2770 opt: 4090 Z-score: 3353.2 bits: 630.5 E(85289): 4.9e-180
Smith-Waterman score: 4090; 98.8% identity (98.8% similar) in 598 aa overlap (1-592:1-598)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHM------TLNNE
::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMFSYVLQTLNNE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE0 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
550 560 570 580 590
>>XP_016864872 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (598 aa)
initn: 4098 init1: 2770 opt: 4090 Z-score: 3353.2 bits: 630.5 E(85289): 4.9e-180
Smith-Waterman score: 4090; 98.8% identity (98.8% similar) in 598 aa overlap (1-592:1-598)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHM------TLNNE
::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMFSYVLQTLNNE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE0 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
550 560 570 580 590
>>XP_016864874 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (666 aa)
initn: 3818 init1: 3818 opt: 3819 Z-score: 3131.5 bits: 589.6 E(85289): 1.1e-167
Smith-Waterman score: 3819; 96.3% identity (97.2% similar) in 574 aa overlap (19-592:94-666)
10 20 30 40
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKD
.:: : :..: . :.:::
XP_016 QAQLERFPRGLAPVASRLAEPASPPPEPQRVLRAWLLAAGSAGTG-REAGGSGTWIQDKD
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE0 DSVDAQNICHVWHMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSVDAQNICHVWHMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCG
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE0 QLAAVHLSKSRTDYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLAAVHLSKSRTDYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNM
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE0 ARNNNDPGRLTEALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARNNNDPGRLTEALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKS
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE0 HSLDLNISEKLTLLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSLDLNISEKLTLLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDP
310 320 330 340 350 360
290 300 310 320 330 340
pF1KE0 SMLLQRFSVAPHETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMLLQRFSVAPHETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQ
370 380 390 400 410 420
350 360 370 380 390 400
pF1KE0 EEHLSPLDFLHSANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEHLSPLDFLHSANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDH
430 440 450 460 470 480
410 420 430 440 450 460
pF1KE0 MTLNNEMSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTLNNEMSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSST
490 500 510 520 530 540
470 480 490 500 510 520
pF1KE0 PCPLCRTIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCPLCRTIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGF
550 560 570 580 590 600
530 540 550 560 570 580
pF1KE0 RRHAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRHAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYF
610 620 630 640 650 660
590
pF1KE0 FFPF
::::
XP_016 FFPF
>>XP_016864873 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (672 aa)
initn: 3804 init1: 2476 opt: 3797 Z-score: 3113.5 bits: 586.3 E(85289): 1.1e-166
Smith-Waterman score: 3797; 95.3% identity (96.2% similar) in 580 aa overlap (19-592:94-672)
10 20 30 40
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKD
.:: : :..: . :.:::
XP_016 QAQLERFPRGLAPVASRLAEPASPPPEPQRVLRAWLLAAGSAGTG-REAGGSGTWIQDKD
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE0 DSVDAQNICHVWHMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSVDAQNICHVWHMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCG
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE0 QLAAVHLSKSRTDYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLAAVHLSKSRTDYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNM
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE0 ARNNNDPGRLTEALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARNNNDPGRLTEALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKS
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE0 HSLDLNISEKLTLLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSLDLNISEKLTLLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDP
310 320 330 340 350 360
290 300 310 320 330 340
pF1KE0 SMLLQRFSVAPHETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMLLQRFSVAPHETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQ
370 380 390 400 410 420
350 360 370 380 390 400
pF1KE0 EEHLSPLDFLHSANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEHLSPLDFLHSANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDH
430 440 450 460 470 480
410 420 430 440 450 460
pF1KE0 M------TLNNEMSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAK
: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFSYVLQTLNNEMSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAK
490 500 510 520 530 540
470 480 490 500 510 520
pF1KE0 DNPSSTPCPLCRTIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNPSSTPCPLCRTIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAF
550 560 570 580 590 600
530 540 550 560 570 580
pF1KE0 HLFGGFRRHAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLFGGFRRHAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVF
610 620 630 640 650 660
590
pF1KE0 CFLCYFFFPF
::::::::::
XP_016 CFLCYFFFPF
670
>>NP_001310221 (OMIM: 616015) E3 ubiquitin-protein ligas (530 aa)
initn: 3614 init1: 3614 opt: 3614 Z-score: 2965.1 bits: 558.5 E(85289): 2e-158
Smith-Waterman score: 3614; 99.8% identity (99.8% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMTLNNEMSTDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMTLNNEMSTDED
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCRTIISRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCRTIISRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 FFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAPVTRRQF
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGKEI
490 500 510 520 530
550 560 570 580 590
pF1KE0 PHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
>>XP_016864875 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (543 aa)
initn: 3592 init1: 2770 opt: 3584 Z-score: 2940.5 bits: 554.0 E(85289): 4.7e-157
Smith-Waterman score: 3584; 98.7% identity (98.7% similar) in 532 aa overlap (1-526:1-532)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHM------TLNNE
::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMFSYVLQTLNNE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGDVQMKKMK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE0 VTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
XP_016 TIQ
>>XP_016864876 (OMIM: 616015) PREDICTED: E3 ubiquitin-pr (505 aa)
initn: 3313 init1: 2770 opt: 3305 Z-score: 2713.1 bits: 511.8 E(85289): 2.2e-144
Smith-Waterman score: 3305; 98.6% identity (98.6% similar) in 491 aa overlap (1-485:1-491)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHM------TLNNE
::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMFSYVLQTLNNE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 TIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAP
:::::::::::
XP_016 TIISRVFFQTEGGGRGRGKGREGKE
490 500
>>NP_848627 (OMIM: 616015) E3 ubiquitin-protein ligase R (416 aa)
initn: 2770 init1: 2770 opt: 2770 Z-score: 2277.2 bits: 430.8 E(85289): 4.2e-120
Smith-Waterman score: 2770; 99.8% identity (99.8% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KE0 MKRSKELITKNHSQGETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_848 MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 HMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 DYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 LLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMTLNNEMSTDED
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMVSIYLLI
370 380 390 400 410
430 440 450 460 470 480
pF1KE0 NEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCRTIISRV
592 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:18:24 2016 done: Fri Nov 4 08:18:25 2016
Total Scan time: 10.360 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]