Result of FASTA (omim) for
pF1KE0028
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0028, 747 aa
1>>>pF1KE0028 747 - 747 aa - 747 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6467+/-0.00038; mu= 11.8463+/- 0.024
mean_var=182.1380+/-37.687, 0's: 0 Z-trim(118.6): 65 B-trim: 0 in 0/55
Lambda= 0.095033
statistics sampled from 31669 (31741) to 31669 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.372), width: 16
Scan time: 13.200
The best scores are: opt bits E(85289)
NP_054868 (OMIM: 616303) WD repeat-containing prot ( 747) 5014 700.2 7.7e-201
XP_016867561 (OMIM: 616303) PREDICTED: WD repeat-c ( 504) 3400 478.8 2.4e-134
XP_016867559 (OMIM: 616303) PREDICTED: WD repeat-c ( 773) 3334 469.9 1.7e-131
XP_011514388 (OMIM: 616303) PREDICTED: WD repeat-c ( 766) 3125 441.2 7.2e-123
XP_011514385 (OMIM: 616303) PREDICTED: WD repeat-c ( 792) 3125 441.3 7.4e-123
XP_016867560 (OMIM: 616303) PREDICTED: WD repeat-c ( 549) 1692 244.6 7.9e-64
>>NP_054868 (OMIM: 616303) WD repeat-containing protein (747 aa)
initn: 5014 init1: 5014 opt: 5014 Z-score: 3726.7 bits: 700.2 E(85289): 7.7e-201
Smith-Waterman score: 5014; 99.9% identity (100.0% similar) in 747 aa overlap (1-747:1-747)
10 20 30 40 50 60
pF1KE0 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNRVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_054 EAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNQVPG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 RLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 RAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 YKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVDWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVDWS
670 680 690 700 710 720
730 740
pF1KE0 TAMDCGTCLTASMDGKIKLTTLLAHKA
:::::::::::::::::::::::::::
NP_054 TAMDCGTCLTASMDGKIKLTTLLAHKA
730 740
>>XP_016867561 (OMIM: 616303) PREDICTED: WD repeat-conta (504 aa)
initn: 3400 init1: 3400 opt: 3400 Z-score: 2533.0 bits: 478.8 E(85289): 2.4e-134
Smith-Waterman score: 3400; 99.8% identity (100.0% similar) in 504 aa overlap (244-747:1-504)
220 230 240 250 260 270
pF1KE0 QQPEEEEALVQHKLPPYVSNMDRLGDSELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSP
::::::::::::::::::::::::::::::
XP_016 MVCSQRNASLSQSPRVGFLSSLLPQSKKSP
10 20 30
280 290 300 310 320 330
pF1KE0 SRLSPAQGPPQPQSSAKKESFGGQGTKGKDPTSGAKDGKSLLSGLATGESGWSQHRQRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLSPAQGPPQPQSSAKKESFGGQGTKGKDPTSGAKDGKSLLSGLATGESGWSQHRQRRL
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE0 QDHGKERKELFSTTTSQCAEKKPEASGPEAEPCPELHTEPVEPLTRASSAGPEGGGVRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDHGKERKELFSTTTSQCAEKKPEASGPEAEPCPELHTEPVEPLTRASSAGPEGGGVRPE
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE0 QPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPL
160 170 180 190 200 210
460 470 480 490 500 510
pF1KE0 LSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCS
220 230 240 250 260 270
520 530 540 550 560 570
pF1KE0 AAAPSLTSQVDFSAPDIGSKGMNRVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHN
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 AAAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHN
280 290 300 310 320 330
580 590 600 610 620 630
pF1KE0 GNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNI
340 350 360 370 380 390
640 650 660 670 680 690
pF1KE0 HKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYK
400 410 420 430 440 450
700 710 720 730 740
pF1KE0 LGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
460 470 480 490 500
>>XP_016867559 (OMIM: 616303) PREDICTED: WD repeat-conta (773 aa)
initn: 3334 init1: 3334 opt: 3334 Z-score: 2481.6 bits: 469.9 E(85289): 1.7e-131
Smith-Waterman score: 4952; 96.5% identity (96.6% similar) in 773 aa overlap (1-747:1-773)
10 20 30 40 50 60
pF1KE0 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDT
430 440 450 460 470 480
490 500 510
pF1KE0 EAKKNLCEININDNMPRI--------------------------LSLACSPNGASFVCSA
:::::::::::::::::: ::::::::::::::::
XP_016 EAKKNLCEININDNMPRIQPQDQSAPSLCGQAEGLTQAHVCCRILSLACSPNGASFVCSA
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 AAPSLTSQVDFSAPDIGSKGMNRVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNG
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 AAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNG
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 NLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIH
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE0 KSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKL
670 680 690 700 710 720
700 710 720 730 740
pF1KE0 GGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
730 740 750 760 770
>>XP_011514388 (OMIM: 616303) PREDICTED: WD repeat-conta (766 aa)
initn: 3125 init1: 3125 opt: 3125 Z-score: 2326.8 bits: 441.2 E(85289): 7.2e-123
Smith-Waterman score: 4966; 97.4% identity (97.5% similar) in 766 aa overlap (1-747:1-766)
10 20 30 40 50 60
pF1KE0 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
370 380 390 400 410 420
430 440 450 460
pF1KE0 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLL--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLQFQWAPSRARPHGK
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 -----LLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLPLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 QVDFSAPDIGSKGMNRVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGA
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE0 ADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVS
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE0 EYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVL
670 680 690 700 710 720
710 720 730 740
pF1KE0 ESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
730 740 750 760
>>XP_011514385 (OMIM: 616303) PREDICTED: WD repeat-conta (792 aa)
initn: 4803 init1: 3125 opt: 3125 Z-score: 2326.6 bits: 441.3 E(85289): 7.4e-123
Smith-Waterman score: 4828; 94.1% identity (94.2% similar) in 779 aa overlap (1-734:1-779)
10 20 30 40 50 60
pF1KE0 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKDPTSGAKDGKSLLSGLATGESGWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSG
370 380 390 400 410 420
430 440 450 460
pF1KE0 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLL--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLQFQWAPSRARPHGK
430 440 450 460 470 480
470 480 490
pF1KE0 -----LLGSGVGTVRLYDTEAKKNLCEININDNMPRI-----------------------
::::::::::::::::::::::::::::::::
XP_011 WLPLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRIQPQDQSAPSLCGQAEGLTQAHVC
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE0 ---LSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNRVPGRLLLWDTKTMKQQLQ
::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 CRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQQLQ
550 560 570 580 590 600
560 570 580 590 600 610
pF1KE0 FSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYD
610 620 630 640 650 660
620 630 640 650 660 670
pF1KE0 ENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSDATGPFVLSGYSGYKQVQVPRGRLFAFD
670 680 690 700 710 720
680 690 700 710 720 730
pF1KE0 SEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDG
730 740 750 760 770 780
740
pF1KE0 KIKLTTLLAHKA
XP_011 KIKLTTLLAHKA
790
>>XP_016867560 (OMIM: 616303) PREDICTED: WD repeat-conta (549 aa)
initn: 3189 init1: 1692 opt: 1692 Z-score: 1266.9 bits: 244.6 E(85289): 7.9e-64
Smith-Waterman score: 3290; 91.6% identity (91.8% similar) in 549 aa overlap (244-747:1-549)
220 230 240 250 260 270
pF1KE0 QQPEEEEALVQHKLPPYVSNMDRLGDSELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSP
::::::::::::::::::::::::::::::
XP_016 MVCSQRNASLSQSPRVGFLSSLLPQSKKSP
10 20 30
280 290 300 310 320 330
pF1KE0 SRLSPAQGPPQPQSSAKKESFGGQGTKGKDPTSGAKDGKSLLSGLATGESGWSQHRQRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLSPAQGPPQPQSSAKKESFGGQGTKGKDPTSGAKDGKSLLSGLATGESGWSQHRQRRL
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE0 QDHGKERKELFSTTTSQCAEKKPEASGPEAEPCPELHTEPVEPLTRASSAGPEGGGVRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDHGKERKELFSTTTSQCAEKKPEASGPEAEPCPELHTEPVEPLTRASSAGPEGGGVRPE
100 110 120 130 140 150
400 410 420 430 440 450
pF1KE0 QPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPL
160 170 180 190 200 210
460 470 480 490
pF1KE0 LSLEWATKRDRLL-------------------LLGSGVGTVRLYDTEAKKNLCEININDN
::::::::::::: ::::::::::::::::::::::::::::
XP_016 LSLEWATKRDRLLQFQWAPSRARPHGKWLPLLLLGSGVGTVRLYDTEAKKNLCEININDN
220 230 240 250 260 270
500 510 520
pF1KE0 MPRI--------------------------LSLACSPNGASFVCSAAAPSLTSQVDFSAP
:::: ::::::::::::::::::::::::::::::
XP_016 MPRIQPQDQSAPSLCGQAEGLTQAHVCCRILSLACSPNGASFVCSAAAPSLTSQVDFSAP
280 290 300 310 320 330
530 540 550 560 570 580
pF1KE0 DIGSKGMNRVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRL
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIGSKGMNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRL
340 350 360 370 380 390
590 600 610 620 630 640
pF1KE0 FDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVSEYSLPSD
400 410 420 430 440 450
650 660 670 680 690 700
pF1KE0 ATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLG
460 470 480 490 500 510
710 720 730 740
pF1KE0 GHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
:::::::::::::::::::::::::::::::::::::::
XP_016 GHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKA
520 530 540
747 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:47:02 2016 done: Fri Nov 4 07:47:04 2016
Total Scan time: 13.200 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]