FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0029, 530 aa 1>>>pF1KE0029 530 - 530 aa - 530 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3981+/-0.000993; mu= 13.5730+/- 0.060 mean_var=89.7108+/-17.507, 0's: 0 Z-trim(106.0): 22 B-trim: 0 in 0/50 Lambda= 0.135410 statistics sampled from 8709 (8718) to 8709 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.268), width: 16 Scan time: 3.360 The best scores are: opt bits E(32554) CCDS2335.1 FAM126B gene_id:285172|Hs108|chr2 ( 530) 3441 682.6 3.1e-196 CCDS5377.1 FAM126A gene_id:84668|Hs108|chr7 ( 521) 1719 346.2 5.6e-95 >>CCDS2335.1 FAM126B gene_id:285172|Hs108|chr2 (530 aa) initn: 3441 init1: 3441 opt: 3441 Z-score: 3636.5 bits: 682.6 E(32554): 3.1e-196 Smith-Waterman score: 3441; 100.0% identity (100.0% similar) in 530 aa overlap (1-530:1-530) 10 20 30 40 50 60 pF1KE0 MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PIGTKPSSSSQRGSLRKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPTDLSVDSV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 ELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNGSQASTSIGVGTEGGTNLA 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 ANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQV 490 500 510 520 530 >>CCDS5377.1 FAM126A gene_id:84668|Hs108|chr7 (521 aa) initn: 1617 init1: 1539 opt: 1719 Z-score: 1818.6 bits: 346.2 E(32554): 5.6e-95 Smith-Waterman score: 1719; 52.1% identity (78.2% similar) in 537 aa overlap (1-526:1-518) 10 20 30 40 50 60 pF1KE0 MLGTDRCVVEEWLSEFKALPDTQITSYAATLHRKKTLVPALYKVIQDSNNELLEPVCHQL :. ... ::::::::::.::.:.. .::..:. :..:: .::::::. ..:::::::::: CCDS53 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 FELYRSSEVRLKRFTLQFLPELMWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNN ::.:::.: .: .:::::::::.: :: ...::. .:.:::::::::.:::::.::.:.. CCDS53 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 KVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEV ::::::::::::::.:::::.::::::::.:: :: : .:::: ::::: .:::::::: CCDS53 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKHWKELCGRIVLDPEFMVQL :.::.::::.:..:::. : ::::.. ::.:: :.:::: ...: . .:: .. ::::. CCDS53 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 LTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSTQEGQKV :::.:.:.:::.:::.:..::::::::::::. .:::::::.: ::: :..:: . CCDS53 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 LKVEVTPTVPRISRTAITTASIRRHRWRREGAEGVNGGEESVNLNDADEGFSSGASLSSQ ..::.::: ::::.:.:. ::: :::.:.: ..: :: ......:::: : :. :.. CCDS53 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PIGTKPSSS--SQRGSL-----RKVATGRSAKDKETASAIKSSESPRDSVVRKQYVQQPT : . :: :.. :. :. .. ..:.::: ..:: .: .::: .:. CCDS53 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKET-----TGESCKDHFARKQ-TQRAQ 370 380 390 400 410 420 430 440 450 460 pF1KE0 DLSVDSVELTPMKKHLSLPAGQVVPKINSLSLIRTASASSSKSFDYVNG----SQASTSI . ...:: .:. :.: ..: .:: .: .: .::.. ::::. :.: . :... CCDS53 S---ENLELLSLKR-LTLTTSQSLPKPSSHGLAKTAATVFSKSFEQVSGVTVPHNPSSAV 420 430 440 450 460 470 470 480 490 500 510 520 pF1KE0 GVGTEGGTNLAANNANRYSTVSLQEDRLGQAGEGKELLSPGAPLTKQSRSPSFNMQLISQ : : :...:::.:. ::::..: ..: :: : . :.: ::... : CCDS53 GCG-------AGTDANRFSACSLQEEKLIYVSERTEL--PMKHQSGQQRPPSISITLSTD 480 490 500 510 520 530 pF1KE0 V 530 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 07:31:18 2016 done: Fri Nov 4 07:31:19 2016 Total Scan time: 3.360 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]