FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0031, 494 aa 1>>>pF1KE0031 494 - 494 aa - 494 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5901+/-0.000459; mu= 12.7168+/- 0.029 mean_var=124.5956+/-25.871, 0's: 0 Z-trim(112.5): 178 B-trim: 1087 in 1/53 Lambda= 0.114901 statistics sampled from 21267 (21479) to 21267 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.252), width: 16 Scan time: 8.740 The best scores are: opt bits E(85289) NP_003306 (OMIM: 601964) dnaJ homolog subfamily C ( 494) 3291 557.4 3.4e-158 XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 2930 497.5 3.2e-140 XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 2930 497.5 3.2e-140 XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 2930 497.5 3.2e-140 XP_016880483 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 2930 497.5 3.2e-140 NP_001138238 (OMIM: 601964) dnaJ homolog subfamily ( 438) 2930 497.5 3.2e-140 NP_006251 (OMIM: 601184,616192) dnaJ homolog subfa ( 504) 635 117.1 1.2e-25 XP_016876163 (OMIM: 601184,616192) PREDICTED: dnaJ ( 421) 578 107.6 7.3e-23 XP_016876164 (OMIM: 601184,616192) PREDICTED: dnaJ ( 383) 528 99.3 2.1e-20 XP_011519407 (OMIM: 601184,616192) PREDICTED: dnaJ ( 450) 528 99.3 2.4e-20 XP_011519406 (OMIM: 601184,616192) PREDICTED: dnaJ ( 533) 529 99.6 2.4e-20 XP_005251485 (OMIM: 611328) PREDICTED: dnaJ homolo ( 348) 291 60.0 1.3e-08 XP_006716814 (OMIM: 611328) PREDICTED: dnaJ homolo ( 348) 291 60.0 1.3e-08 NP_036398 (OMIM: 611328) dnaJ homolog subfamily B ( 348) 291 60.0 1.3e-08 NP_001128477 (OMIM: 611328) dnaJ homolog subfamily ( 420) 291 60.0 1.5e-08 XP_011516144 (OMIM: 611328) PREDICTED: dnaJ homolo ( 420) 291 60.0 1.5e-08 NP_001128476 (OMIM: 611328) dnaJ homolog subfamily ( 462) 291 60.0 1.6e-08 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 289 59.7 2.1e-08 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 289 59.7 2.2e-08 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 289 59.8 2.3e-08 NP_001304028 (OMIM: 611327) dnaJ homolog subfamily ( 337) 281 58.3 4.1e-08 NP_008965 (OMIM: 611327) dnaJ homolog subfamily B ( 337) 281 58.3 4.1e-08 NP_001530 (OMIM: 602837) dnaJ homolog subfamily A ( 397) 273 57.0 1.2e-07 NP_001304032 (OMIM: 611327) dnaJ homolog subfamily ( 77) 248 52.3 5.9e-07 NP_001002762 (OMIM: 608376) dnaJ homolog subfamily ( 409) 259 54.7 5.9e-07 XP_005269989 (OMIM: 608376) PREDICTED: dnaJ homolo ( 409) 259 54.7 5.9e-07 NP_060096 (OMIM: 608376) dnaJ homolog subfamily B ( 409) 259 54.7 5.9e-07 XP_005269988 (OMIM: 608376) PREDICTED: dnaJ homolo ( 411) 259 54.7 5.9e-07 XP_016867122 (OMIM: 603511,611332) PREDICTED: dnaJ ( 211) 249 52.8 1.1e-06 NP_005485 (OMIM: 603511,611332) dnaJ homolog subfa ( 241) 249 52.9 1.2e-06 XP_006715886 (OMIM: 603511,611332) PREDICTED: dnaJ ( 257) 249 52.9 1.3e-06 NP_490647 (OMIM: 603511,611332) dnaJ homolog subfa ( 326) 249 53.0 1.6e-06 XP_005249573 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 249 53.0 1.6e-06 XP_005249572 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 249 53.0 1.6e-06 XP_011514006 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 249 53.0 1.6e-06 NP_001269429 (OMIM: 601963) tetratricopeptide repe ( 292) 245 52.3 2.3e-06 NP_003305 (OMIM: 601963) tetratricopeptide repeat ( 292) 245 52.3 2.3e-06 NP_057390 (OMIM: 611341) dnaJ homolog subfamily B ( 358) 243 52.0 3.3e-06 NP_660157 (OMIM: 611336) dnaJ homolog subfamily B ( 309) 237 51.0 6e-06 NP_001034639 (OMIM: 604139,614881,617017) dnaJ hom ( 277) 236 50.8 6.1e-06 NP_006136 (OMIM: 604572) dnaJ homolog subfamily B ( 340) 237 51.0 6.4e-06 NP_006727 (OMIM: 604139,614881,617017) dnaJ homolo ( 324) 236 50.8 6.9e-06 NP_055635 (OMIM: 606081) mitochondrial import rece ( 608) 236 51.0 1.1e-05 NP_003012 (OMIM: 603419) small glutamine-rich tetr ( 313) 223 48.6 3e-05 XP_011526480 (OMIM: 603419) PREDICTED: small gluta ( 313) 223 48.6 3e-05 NP_001269582 (OMIM: 605063) stress-induced-phospho ( 519) 226 49.3 3.1e-05 NP_006810 (OMIM: 605063) stress-induced-phosphopro ( 543) 226 49.3 3.2e-05 XP_006713582 (OMIM: 611337) PREDICTED: dnaJ homolo ( 232) 220 48.0 3.4e-05 NP_699161 (OMIM: 611337) dnaJ homolog subfamily B ( 232) 220 48.0 3.4e-05 NP_001269581 (OMIM: 605063) stress-induced-phospho ( 590) 226 49.4 3.4e-05 >>NP_003306 (OMIM: 601964) dnaJ homolog subfamily C memb (494 aa) initn: 3291 init1: 3291 opt: 3291 Z-score: 2961.1 bits: 557.4 E(85289): 3.4e-158 Smith-Waterman score: 3291; 99.8% identity (100.0% similar) in 494 aa overlap (1-494:1-494) 10 20 30 40 50 60 pF1KE0 MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 RALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEV ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: NP_003 KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 QKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFS 430 440 450 460 470 480 490 pF1KE0 FEASGPGNFFFQFG :::::::::::::: NP_003 FEASGPGNFFFQFG 490 >>XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2638.4 bits: 497.5 E(85289): 3.2e-140 Smith-Waterman score: 2930; 99.8% identity (100.0% similar) in 438 aa overlap (57-494:1-438) 30 40 50 60 70 80 pF1KE0 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ :::::::::::::::::::::::::::::: XP_011 MCPKNASYYGNRAATLMMLGRFREALGDAQ 10 20 30 90 100 110 120 130 140 pF1KE0 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE0 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKIL ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: XP_011 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKIL 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE0 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR 340 350 360 370 380 390 450 460 470 480 490 pF1KE0 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG 400 410 420 430 >>XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2638.4 bits: 497.5 E(85289): 3.2e-140 Smith-Waterman score: 2930; 99.8% identity (100.0% similar) in 438 aa overlap (57-494:1-438) 30 40 50 60 70 80 pF1KE0 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ :::::::::::::::::::::::::::::: XP_011 MCPKNASYYGNRAATLMMLGRFREALGDAQ 10 20 30 90 100 110 120 130 140 pF1KE0 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE0 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKIL ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: XP_011 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKIL 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE0 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR 340 350 360 370 380 390 450 460 470 480 490 pF1KE0 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG 400 410 420 430 >>XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2638.4 bits: 497.5 E(85289): 3.2e-140 Smith-Waterman score: 2930; 99.8% identity (100.0% similar) in 438 aa overlap (57-494:1-438) 30 40 50 60 70 80 pF1KE0 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ :::::::::::::::::::::::::::::: XP_011 MCPKNASYYGNRAATLMMLGRFREALGDAQ 10 20 30 90 100 110 120 130 140 pF1KE0 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE0 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKIL ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: XP_011 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKIL 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE0 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR 340 350 360 370 380 390 450 460 470 480 490 pF1KE0 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG 400 410 420 430 >>XP_016880483 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2638.4 bits: 497.5 E(85289): 3.2e-140 Smith-Waterman score: 2930; 99.8% identity (100.0% similar) in 438 aa overlap (57-494:1-438) 30 40 50 60 70 80 pF1KE0 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ :::::::::::::::::::::::::::::: XP_016 MCPKNASYYGNRAATLMMLGRFREALGDAQ 10 20 30 90 100 110 120 130 140 pF1KE0 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE0 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKIL ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: XP_016 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKIL 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE0 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR 340 350 360 370 380 390 450 460 470 480 490 pF1KE0 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG 400 410 420 430 >>NP_001138238 (OMIM: 601964) dnaJ homolog subfamily C m (438 aa) initn: 2930 init1: 2930 opt: 2930 Z-score: 2638.4 bits: 497.5 E(85289): 3.2e-140 Smith-Waterman score: 2930; 99.8% identity (100.0% similar) in 438 aa overlap (57-494:1-438) 30 40 50 60 70 80 pF1KE0 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ :::::::::::::::::::::::::::::: NP_001 MCPKNASYYGNRAATLMMLGRFREALGDAQ 10 20 30 90 100 110 120 130 140 pF1KE0 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE0 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE0 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKA 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE0 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDT 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE0 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKIL ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: NP_001 YIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKIL 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE0 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTR 340 350 360 370 380 390 450 460 470 480 490 pF1KE0 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG 400 410 420 430 >>NP_006251 (OMIM: 601184,616192) dnaJ homolog subfamily (504 aa) initn: 320 init1: 184 opt: 635 Z-score: 581.5 bits: 117.1 E(85289): 1.2e-25 Smith-Waterman score: 635; 28.3% identity (62.7% similar) in 480 aa overlap (27-493:36-503) 10 20 30 40 50 pF1KE0 MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAID ..: : :. : . .: . . :.: NP_006 SVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC : : : ::.... .:. . :: : . ..: .:. ..:..:. :. :. : NP_006 GDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE0 RSFQRALELD---HKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAP .:...:. . ... .::... ... ... .. : . : . :. .. .:. :: NP_006 DDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE0 ACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYE--DCIEKAVQ ... :.:::. :. .: : . .. . :..:.: . :::. : : ... NP_006 WDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFY-KISTLYYQLGDH-ELSLS 190 200 210 220 230 240 240 250 260 270 280 pF1KE0 FFVQALRMAPDHEKACIAC-RNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN-- . :.. :: : :.: ...: :. :.... ...: : : : .. .:. NP_006 EVRECLKLDQDH-KRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIA 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE0 --NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEE ..... .. :. :: .: .::. :....... ..: ::. :. :.:.: NP_006 EYTVRSKERI-CH---CFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDE 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 AVRDYEKVYQ-TEKTKEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRA :..::: . . .:. .. .. :..:: :..:...:::::::: .::...:: ::::: : NP_006 AIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLA 360 370 380 390 400 410 410 420 430 440 450 460 pF1KE0 LMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEEGMNMGDFD :. ::: . . : .:. :::: ... : .::::. . ..:.:.: :: :... : . NP_006 LQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGN 420 430 440 450 460 470 470 480 490 pF1KE0 PNNIFKAFFGGPGGFS-FEASGPGNFFFQFG : :. ... ::. : ..:: : :.: NP_006 P---FHRSWNSWQGFNPFSSGGPFRFKFHFN 480 490 500 >>XP_016876163 (OMIM: 601184,616192) PREDICTED: dnaJ hom (421 aa) initn: 294 init1: 184 opt: 578 Z-score: 531.5 bits: 107.6 E(85289): 7.3e-23 Smith-Waterman score: 578; 28.5% identity (64.0% similar) in 431 aa overlap (75-493:1-420) 50 60 70 80 90 100 pF1KE0 NEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGK .:. . :: : . ..: .:. ..:..:. XP_016 MGKSKAALPDLTKVIQLKMDFTAARLQRGH 10 20 30 110 120 130 140 150 160 pF1KE0 CHLSLGNAMAACRSFQRALELD---HKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKV :. :. : .:...:. . ... .::... ... ... .. : . : . :. . XP_016 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAA 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE0 VFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLY . .:. :: ... :.:::. :. .: : . .. . :..:.: . :: XP_016 IAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFY-KISTLY 100 110 120 130 140 230 240 250 260 270 pF1KE0 YE-DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKEDGNKAFKEGNYKLAYELY :. : ... . :.. :: : :.: ...: :. :.... ...: : : : XP_016 YQLGDHELSLSEVRECLKLDQDH-KRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKY 150 160 170 180 190 200 280 290 300 310 320 330 pF1KE0 TEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRA .. .:. ..... .. :. :: .: .::. :....... ..: :: XP_016 ESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRA 210 220 230 240 250 260 340 350 360 370 380 390 pF1KE0 QCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELRKSKRKDYYKILGVDKNASE . :. :.:.::..::: . . .:. .. .. :..:: :..:...:::::::: .::.. XP_016 EAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKK 270 280 290 300 310 320 400 410 420 430 440 450 pF1KE0 DEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-L .:: ::::: ::. ::: . . : .:. :::: ... : .::::. . ..:.:.: : XP_016 QEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPL 330 340 350 360 370 380 460 470 480 490 pF1KE0 DEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG : :... : .: :. ... ::. : ..:: : :.: XP_016 DAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN 390 400 410 420 >>XP_016876164 (OMIM: 601184,616192) PREDICTED: dnaJ hom (383 aa) initn: 264 init1: 184 opt: 528 Z-score: 487.3 bits: 99.3 E(85289): 2.1e-20 Smith-Waterman score: 528; 29.1% identity (64.8% similar) in 378 aa overlap (126-493:17-382) 100 110 120 130 140 150 pF1KE0 VRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEK .... .::... ... ... .. : . : . XP_016 MCFLHFFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGS 10 20 30 40 160 170 180 190 200 210 pF1KE0 RDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYV :. .. .:. :: ... :.:::. :. .: : . .. . :..:.: XP_016 GDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFY- 50 60 70 80 90 100 220 230 240 250 260 270 pF1KE0 RGLCLYYE--DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKEDGNKAFKEGNY . :::. : : ... . :.. ::.. :.: ...: :. :.... ...: : XP_016 KISTLYYQLGDH-ELSLSEVRECLKLDQDHKR-CFAHYKQVKKLNKLIESAEELIRDGRY 110 120 130 140 150 160 280 290 300 310 320 pF1KE0 KLAYELYTEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYI : : .. .:. ..... .. :. :: .: .::. :....... . XP_016 TDATSKYESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCSEVLQMEPDNV 170 180 190 200 210 330 340 350 360 370 380 pF1KE0 KAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELRKSKRKDYYKILG .: ::. :. :.:.::..::: . . .:. .. .. :..:: :..:...::::::: XP_016 NALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILG 220 230 240 250 260 270 390 400 410 420 430 440 pF1KE0 VDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRY : .::...:: ::::: ::. ::: . . : .:. :::: ... : .::::. . .. XP_016 VKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEVLSDPEMRKKF 280 290 300 310 320 330 450 460 470 480 490 pF1KE0 DSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG :.:.: :: :... : .: :. ... ::. : ..:: : :.: XP_016 DDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN 340 350 360 370 380 >>XP_011519407 (OMIM: 601184,616192) PREDICTED: dnaJ hom (450 aa) initn: 318 init1: 184 opt: 528 Z-score: 486.3 bits: 99.3 E(85289): 2.4e-20 Smith-Waterman score: 528; 29.1% identity (64.8% similar) in 378 aa overlap (126-493:84-449) 100 110 120 130 140 150 pF1KE0 VRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEK .... .::... ... ... .. : . : . XP_011 SLLGLQRSLLDDLYLLFWFFLMKKLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGS 60 70 80 90 100 110 160 170 180 190 200 210 pF1KE0 RDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYV :. .. .:. :: ... :.:::. :. .: : . .. . :..:.: XP_011 GDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFY- 120 130 140 150 160 170 220 230 240 250 260 270 pF1KE0 RGLCLYYE--DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKEDGNKAFKEGNY . :::. : : ... . :.. ::.. :.: ...: :. :.... ...: : XP_011 KISTLYYQLGDH-ELSLSEVRECLKLDQDHKR-CFAHYKQVKKLNKLIESAEELIRDGRY 180 190 200 210 220 230 280 290 300 310 320 pF1KE0 KLAYELYTEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYI : : .. .:. ..... .. :. :: .: .::. :....... . XP_011 TDATSKYESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCSEVLQMEPDNV 240 250 260 270 280 330 340 350 360 370 380 pF1KE0 KAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELRKSKRKDYYKILG .: ::. :. :.:.::..::: . . .:. .. .. :..:: :..:...::::::: XP_011 NALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILG 290 300 310 320 330 340 390 400 410 420 430 440 pF1KE0 VDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRY : .::...:: ::::: ::. ::: . . : .:. :::: ... : .::::. . .. XP_011 VKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEVLSDPEMRKKF 350 360 370 380 390 400 450 460 470 480 490 pF1KE0 DSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG :.:.: :: :... : .: :. ... ::. : ..:: : :.: XP_011 DDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN 410 420 430 440 450 494 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:52:13 2016 done: Sat Nov 5 21:52:14 2016 Total Scan time: 8.740 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]