Result of FASTA (omim) for
pF1KE0035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0035, 336 aa
1>>>pF1KE0035 336 - 336 aa - 336 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3218+/-0.000347; mu= 21.8465+/- 0.022
mean_var=70.2590+/-13.844, 0's: 0 Z-trim(114.0): 78 B-trim: 0 in 0/54
Lambda= 0.153011
statistics sampled from 23578 (23664) to 23578 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.277), width: 16
Scan time: 8.060
The best scores are: opt bits E(85289)
NP_065956 (OMIM: 616796) retinol dehydrogenase 14 ( 336) 2192 493.0 3.8e-139
NP_689656 (OMIM: 608830,612712) retinol dehydrogen ( 316) 744 173.3 6.1e-43
NP_057110 (OMIM: 607849,616108) retinol dehydrogen ( 318) 726 169.3 9.7e-42
NP_653284 (OMIM: 616157) dehydrogenase/reductase S ( 377) 615 144.9 2.6e-34
NP_001278926 (OMIM: 605131,614322,616211) WW domai ( 301) 517 123.2 7.2e-28
NP_057457 (OMIM: 605131,614322,616211) WW domain-c ( 414) 517 123.3 8.9e-28
XP_011521406 (OMIM: 605131,614322,616211) PREDICTE ( 353) 367 90.1 7.4e-18
XP_011521405 (OMIM: 605131,614322,616211) PREDICTE ( 367) 367 90.2 7.6e-18
XP_011521403 (OMIM: 605131,614322,616211) PREDICTE ( 414) 367 90.2 8.3e-18
XP_005266584 (OMIM: 616163) PREDICTED: dehydrogena ( 268) 257 65.7 1.3e-10
NP_001239579 (OMIM: 607849,616108) retinol dehydro ( 248) 256 65.5 1.4e-10
NP_078981 (OMIM: 616163) dehydrogenase/reductase S ( 242) 250 64.1 3.5e-10
XP_016876240 (OMIM: 616163) PREDICTED: dehydrogena ( 216) 217 56.8 5e-08
NP_001026889 (OMIM: 616163) dehydrogenase/reductas ( 271) 214 56.2 9.2e-08
XP_011533538 (OMIM: 616163) PREDICTED: dehydrogena ( 323) 213 56.1 1.2e-07
XP_011533540 (OMIM: 616163) PREDICTED: dehydrogena ( 274) 206 54.5 3.1e-07
XP_016876241 (OMIM: 616163) PREDICTED: dehydrogena ( 183) 201 53.2 5.2e-07
XP_016876239 (OMIM: 616163) PREDICTED: dehydrogena ( 225) 159 44.0 0.00037
XP_005266585 (OMIM: 616163) PREDICTED: dehydrogena ( 232) 159 44.0 0.00037
XP_016876238 (OMIM: 616163) PREDICTED: dehydrogena ( 255) 159 44.1 0.0004
NP_001257353 (OMIM: 616163) dehydrogenase/reductas ( 317) 159 44.2 0.00046
XP_011533537 (OMIM: 616163) PREDICTED: dehydrogena ( 346) 159 44.2 0.00049
NP_055049 (OMIM: 601417) estradiol 17-beta-dehydro ( 261) 157 43.6 0.00055
NP_570607 (OMIM: 605131,614322,616211) WW domain-c ( 189) 155 43.0 0.0006
XP_016878767 (OMIM: 605131,614322,616211) PREDICTE ( 250) 150 42.1 0.0016
XP_011521407 (OMIM: 605131,614322,616211) PREDICTE ( 248) 148 41.6 0.0021
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303) 147 41.5 0.0028
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 143 40.6 0.0051
NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine ( 332) 143 40.7 0.0055
XP_011533539 (OMIM: 616163) PREDICTED: dehydrogena ( 297) 141 40.2 0.0069
>>NP_065956 (OMIM: 616796) retinol dehydrogenase 14 [Hom (336 aa)
initn: 2192 init1: 2192 opt: 2192 Z-score: 2619.0 bits: 493.0 E(85289): 3.8e-139
Smith-Waterman score: 2192; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KE0 MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 TVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSG
250 260 270 280 290 300
310 320 330
pF1KE0 RYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
::::::::::::::::::::::::::::::::::::
NP_065 RYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
310 320 330
>>NP_689656 (OMIM: 608830,612712) retinol dehydrogenase (316 aa)
initn: 880 init1: 583 opt: 744 Z-score: 891.9 bits: 173.3 E(85289): 6.1e-43
Smith-Waterman score: 883; 46.3% identity (72.8% similar) in 313 aa overlap (25-334:18-313)
10 20 30 40 50
pF1KE0 MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGG---DPGLMHGKTVLITGANSGLGR
:.: .... :: . ::.:.:::::.:.:.
NP_689 MLVTLGLLTSFFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVITGANTGIGK
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 ATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLA
:: :: :::: ..::: ..: ::...: . ... ...::.:::.
NP_689 ETARELASRGARVYIACRDVLKGESAASEIRVDTKNS-------------QVLVRKLDLS
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 SLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLG
. .:.::: . .: :: .: .::::::...::: :: :::: ..::::::::::: :::
NP_689 DTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 LLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEG
:: :::.:.: ::: .. : : : ::.::. :...: : .:::::.:::::::.::.:
NP_689 RLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 TNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEG
:.::. ..:::.::..: :: . :. ::. : :: ::::::.. : . .:
NP_689 TGVTTYAVHPGVVRSELVRHSSLLCLLWRLFS----PFVKTAREGAQTSLHCALAEGLEP
230 240 250 260 270
300 310 320 330
pF1KE0 VSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
.::.::.:::. . :.: ....:..::..: ..:.
NP_689 LSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGIRWE
280 290 300 310
>>NP_057110 (OMIM: 607849,616108) retinol dehydrogenase (318 aa)
initn: 867 init1: 564 opt: 726 Z-score: 870.4 bits: 169.3 E(85289): 9.7e-42
Smith-Waterman score: 845; 45.7% identity (73.3% similar) in 311 aa overlap (27-334:22-315)
10 20 30 40 50
pF1KE0 MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGG---DPGLMHGKTVLITGANSGLGR
:..... .: . . ::.:..::::.:.:.
NP_057 MVELMFPLLLLLLPFLLYMAAPQIRKMLSSGVCTSTVQLPGKVVVVTGANTGIGK
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 ATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLA
:: :: . :::: ..::: ..: .: ... ..: ...::.:::.
NP_057 ETAKELAQRGARVYLACRDVEKGELVAKEIQT-------------TTGNQQVLVRKLDLS
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 SLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLG
. .:.::: . .: :: .: :::::::...::: :: :::::..:::::::::::.:::
NP_057 DTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 LLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEG
:: ::::::: ::: .. : :.: .:..:. :: .. : .:::::::::.::::::.:
NP_057 KLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELARRLKG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 TNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEG
..::. .::: :...: :: ... .. : :. :.::: .:::::.. : . .:
NP_057 SGVTTYSVHPGTVQSELVRH---SSFMRWMWWLFSF-FIKTPQQGAQTSLHCALTEGLEI
230 240 250 260 270
300 310 320 330
pF1KE0 VSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
.:: .:.::. . .: .:..::.:::.: ..::
NP_057 LSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID
280 290 300 310
>>NP_653284 (OMIM: 616157) dehydrogenase/reductase SDR f (377 aa)
initn: 591 init1: 225 opt: 615 Z-score: 737.1 bits: 144.9 E(85289): 2.6e-34
Smith-Waterman score: 782; 43.2% identity (69.4% similar) in 324 aa overlap (13-334:6-313)
10 20 30 40 50 60
pF1KE0 MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATA
::..: :.: .: . . : : ..:.:...::::::.:. ::
NP_653 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTA
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 AELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLR
:: : ::::...::.. :.: :: .::.: :: .:.: ::::::
NP_653 LELARRGARVVLACRSQERGEAAAFDLRQE-------------SGNNEVIFMALDLASLA
60 70 80 90 100
130 140 150 160 170 180
pF1KE0 SVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLK
::::: .:. :::::.::.:::: .: .:...:.. . :::.: ::::.::: ::
NP_653 SVRAFATAFLSSEPRLDILIHNAGISSCG--RTREAFNLLLRVNHIGPFLLTHLLLPCLK
110 120 130 140 150
190 200 210 220 230
pF1KE0 SSAPSRIVVVSSKLYKYGDINFDDLNSEQ-SYNKSF-CYSRSKLANILFTRELARRLEGT
. ::::.:::.: . : ..: :. .. . . :. .::::.::.:::: .::.:
NP_653 ACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEAT
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 NVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGV
.:: . ::: : ..: . :.: ..::. ..: ...: :::: .: : . .: .
NP_653 GVTCYAAHPGPVNSELFLR-HVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPL
220 230 240 250 260 270
300 310 320 330
pF1KE0 SGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
:::::..:. ::. : : :. .:..::. :. ..::
NP_653 SGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLS
280 290 300 310 320 330
NP_653 TPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEIQLS
340 350 360 370
>>NP_001278926 (OMIM: 605131,614322,616211) WW domain-co (301 aa)
initn: 666 init1: 259 opt: 517 Z-score: 621.3 bits: 123.2 E(85289): 7.2e-28
Smith-Waterman score: 632; 40.5% identity (65.9% similar) in 299 aa overlap (43-332:11-292)
20 30 40 50 60 70
pF1KE0 LGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIM
::.:..::::::.: :: . ::.::.
NP_001 MEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVIL
10 20 30 40
80 90 100 110 120 130
pF1KE0 GCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQE
.::. ::: ::.... .: ..: .. . :::: ::::. : . . .
NP_001 ACRNMARASEAVSRILEEWHKA-------------KVEAMTLDLALLRSVQHFAEAFKAK
50 60 70 80
140 150 160 170 180 190
pF1KE0 EPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSS
. : ::. ::. : :. :.::.: : ::::::: :..:: .: :::.:..::::
NP_001 NVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSS
90 100 110 120 130 140
200 210 220 230 240
pF1KE0 KLYKYGDIN-------FDDLN-SEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNV
. ... ::: :. :. ....: . :.:::: ::::. :: ::: .:: :.
NP_001 ESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 LHPG-IVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYF
.::: .. .:. : . : ::.:. : :. .:: :..: :. ::.::..: ::
NP_001 VHPGNMMYSNIHRSWWVYTL---LFTLAR-PFTKSMQQGAATTVYCAAVPELEGLGGMYF
210 220 230 240 250 260
310 320 330
pF1KE0 GDCKEEELLPKAMDESVARKLWDISEVMVGLLK
..: . :.:..: .:: :: .:: ..
NP_001 NNCCRCMPSPEAQSEETARTLWALSERLIQERLGSQSG
270 280 290 300
>>NP_057457 (OMIM: 605131,614322,616211) WW domain-conta (414 aa)
initn: 666 init1: 259 opt: 517 Z-score: 619.7 bits: 123.3 E(85289): 8.9e-28
Smith-Waterman score: 632; 40.5% identity (65.9% similar) in 299 aa overlap (43-332:124-405)
20 30 40 50 60 70
pF1KE0 LGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIM
::.:..::::::.: :: . ::.::.
NP_057 VDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVIL
100 110 120 130 140 150
80 90 100 110 120 130
pF1KE0 GCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQE
.::. ::: ::.... .: ..: .. . :::: ::::. : . . .
NP_057 ACRNMARASEAVSRILEEWHKA-------------KVEAMTLDLALLRSVQHFAEAFKAK
160 170 180 190 200
140 150 160 170 180 190
pF1KE0 EPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSS
. : ::. ::. : :. :.::.: : ::::::: :..:: .: :::.:..::::
NP_057 NVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSS
210 220 230 240 250 260
200 210 220 230 240
pF1KE0 KLYKYGDIN-------FDDLN-SEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNV
. ... ::: :. :. ....: . :.:::: ::::. :: ::: .:: :.
NP_057 ESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNA
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 LHPG-IVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYF
.::: .. .:. : . : ::.:. : :. .:: :..: :. ::.::..: ::
NP_057 VHPGNMMYSNIHRSWWVYTL---LFTLAR-PFTKSMQQGAATTVYCAAVPELEGLGGMYF
330 340 350 360 370
310 320 330
pF1KE0 GDCKEEELLPKAMDESVARKLWDISEVMVGLLK
..: . :.:..: .:: :: .:: ..
NP_057 NNCCRCMPSPEAQSEETARTLWALSERLIQERLGSQSG
380 390 400 410
>>XP_011521406 (OMIM: 605131,614322,616211) PREDICTED: W (353 aa)
initn: 509 init1: 259 opt: 367 Z-score: 441.5 bits: 90.1 E(85289): 7.4e-18
Smith-Waterman score: 482; 41.7% identity (66.4% similar) in 223 aa overlap (43-256:124-333)
20 30 40 50 60 70
pF1KE0 LGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIM
::.:..::::::.: :: . ::.::.
XP_011 VDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVIL
100 110 120 130 140 150
80 90 100 110 120 130
pF1KE0 GCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQE
.::. ::: ::.... .: ..: .. . :::: ::::. : . . .
XP_011 ACRNMARASEAVSRILEEWHKA-------------KVEAMTLDLALLRSVQHFAEAFKAK
160 170 180 190 200
140 150 160 170 180 190
pF1KE0 EPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSS
. : ::. ::. : :. :.::.: : ::::::: :..:: .: :::.:..::::
XP_011 NVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSS
210 220 230 240 250 260
200 210 220 230 240
pF1KE0 KLYKYGDIN-------FDDLN-SEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNV
. ... ::: :. :. ....: . :.:::: ::::. :: ::: .:: :.
XP_011 ESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNA
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 LHPG-IVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYF
.::: .. .:. :
XP_011 VHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMD
330 340 350
>>XP_011521405 (OMIM: 605131,614322,616211) PREDICTED: W (367 aa)
initn: 509 init1: 259 opt: 367 Z-score: 441.3 bits: 90.2 E(85289): 7.6e-18
Smith-Waterman score: 482; 41.7% identity (66.4% similar) in 223 aa overlap (43-256:124-333)
20 30 40 50 60 70
pF1KE0 LGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIM
::.:..::::::.: :: . ::.::.
XP_011 VDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVIL
100 110 120 130 140 150
80 90 100 110 120 130
pF1KE0 GCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQE
.::. ::: ::.... .: ..: .. . :::: ::::. : . . .
XP_011 ACRNMARASEAVSRILEEWHKA-------------KVEAMTLDLALLRSVQHFAEAFKAK
160 170 180 190 200
140 150 160 170 180 190
pF1KE0 EPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSS
. : ::. ::. : :. :.::.: : ::::::: :..:: .: :::.:..::::
XP_011 NVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSS
210 220 230 240 250 260
200 210 220 230 240
pF1KE0 KLYKYGDIN-------FDDLN-SEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNV
. ... ::: :. :. ....: . :.:::: ::::. :: ::: .:: :.
XP_011 ESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNA
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 LHPG-IVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYF
.::: .. .:. :
XP_011 VHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMEKPAAMLGGYSSIPV
330 340 350 360
>>XP_011521403 (OMIM: 605131,614322,616211) PREDICTED: W (414 aa)
initn: 509 init1: 259 opt: 367 Z-score: 440.7 bits: 90.2 E(85289): 8.3e-18
Smith-Waterman score: 482; 41.7% identity (66.4% similar) in 223 aa overlap (43-256:124-333)
20 30 40 50 60 70
pF1KE0 LGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIM
::.:..::::::.: :: . ::.::.
XP_011 VDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVIL
100 110 120 130 140 150
80 90 100 110 120 130
pF1KE0 GCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQE
.::. ::: ::.... .: ..: .. . :::: ::::. : . . .
XP_011 ACRNMARASEAVSRILEEWHKA-------------KVEAMTLDLALLRSVQHFAEAFKAK
160 170 180 190 200
140 150 160 170 180 190
pF1KE0 EPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSS
. : ::. ::. : :. :.::.: : ::::::: :..:: .: :::.:..::::
XP_011 NVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSS
210 220 230 240 250 260
200 210 220 230 240
pF1KE0 KLYKYGDIN-------FDDLN-SEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNV
. ... ::: :. :. ....: . :.:::: ::::. :: ::: .:: :.
XP_011 ESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNA
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 LHPG-IVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYF
.::: .. .:. :
XP_011 VHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMLFDSAWLLADCWLLAGGTPQLLEASTVP
330 340 350 360 370 380
>>XP_005266584 (OMIM: 616163) PREDICTED: dehydrogenase/r (268 aa)
initn: 201 init1: 154 opt: 257 Z-score: 311.7 bits: 65.7 E(85289): 1.3e-10
Smith-Waterman score: 257; 29.7% identity (58.5% similar) in 229 aa overlap (114-336:49-268)
90 100 110 120 130 140
pF1KE0 AGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNA
.::.. ... : : ...: .: ::::::
XP_005 EESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFV-ENFKQEHKLHVLINNA
20 30 40 50 60 70
150 160 170 180 190 200
pF1KE0 GIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFD
: . ::::.: .:..: :: ..::. :. .:.. :...::: . .: .
XP_005 GCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTN
80 90 100 110 120 130
210 220 230 240 250 260
pF1KE0 DLNSEQS-YNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPL
::.::.. .. .. :...: ....:.. :. . . .::: . : :.
XP_005 DLQSERTPFDGTMVYAQNKRQQVVLTERWAQG--HPAIHFSSMHPGWADTPGVRQAM---
140 150 160 170 180 190
270 280 290 300 310 320
pF1KE0 LVKPLFNLVSWAFFKTPVEGAQTSIYLA-SSPEVEGVSGRYFGDCKEEEL-LPKAMDESV
: :. ... ..::.: ..:: :: . :::.: : : :: : :
XP_005 ---PGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSS
200 210 220 230 240
330
pF1KE0 A---RKLWDISEVMVGLLK
.:: .: : .. .:
XP_005 PAEEEKLIEILEQLAQTFK
250 260
336 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:59:55 2016 done: Fri Nov 4 06:59:56 2016
Total Scan time: 8.060 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]