Result of FASTA (omim) for pF1KE0037
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0037, 740 aa
  1>>>pF1KE0037 740 - 740 aa - 740 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6536+/-0.000378; mu= 19.0992+/- 0.024
 mean_var=90.5745+/-18.398, 0's: 0 Z-trim(113.7): 91  B-trim: 0 in 0/54
 Lambda= 0.134763
 statistics sampled from 23148 (23239) to 23148 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.272), width:  16
 Scan time: 12.920

The best scores are:                                      opt bits E(85289)
NP_005459 (OMIM: 602640) N-acetylated-alpha-linked ( 740) 4911 965.6       0
XP_011543009 (OMIM: 602640) PREDICTED: N-acetylate ( 692) 4606 906.3       0
XP_011543008 (OMIM: 602640) PREDICTED: N-acetylate ( 737) 4497 885.1       0
XP_011543011 (OMIM: 602640) PREDICTED: N-acetylate ( 547) 3605 711.6 2.1e-204
XP_011543012 (OMIM: 602640) PREDICTED: N-acetylate ( 522) 3387 669.2 1.2e-191
XP_011543014 (OMIM: 602640) PREDICTED: N-acetylate ( 508) 3035 600.7 4.6e-171
XP_011543013 (OMIM: 602640) PREDICTED: N-acetylate ( 508) 3035 600.7 4.6e-171
XP_011543010 (OMIM: 602640) PREDICTED: N-acetylate ( 687) 3024 598.7 2.6e-170
NP_004467 (OMIM: 600934) glutamate carboxypeptidas ( 750) 1737 348.5 5.8e-95
XP_016872923 (OMIM: 600934) PREDICTED: glutamate c ( 735) 1726 346.4 2.5e-94
NP_001180400 (OMIM: 600934) glutamate carboxypepti ( 735) 1726 346.4 2.5e-94
XP_016872921 (OMIM: 600934) PREDICTED: glutamate c ( 805) 1726 346.4 2.7e-94
XP_016872926 (OMIM: 600934) PREDICTED: glutamate c ( 693) 1723 345.8 3.6e-94
XP_016872931 (OMIM: 600934) PREDICTED: glutamate c ( 693) 1723 345.8 3.6e-94
XP_016872932 (OMIM: 600934) PREDICTED: glutamate c ( 693) 1723 345.8 3.6e-94
XP_016872925 (OMIM: 600934) PREDICTED: glutamate c ( 693) 1723 345.8 3.6e-94
NP_005458 (OMIM: 611636) N-acetylated-alpha-linked ( 740) 1721 345.4 4.9e-94
XP_016872532 (OMIM: 611636) PREDICTED: N-acetylate ( 775) 1721 345.4 5.1e-94
XP_016872534 (OMIM: 611636) PREDICTED: N-acetylate ( 686) 1697 340.7 1.2e-92
XP_016872808 (OMIM: 609020) PREDICTED: putative N- ( 693) 1697 340.7 1.2e-92
NP_001014986 (OMIM: 600934) glutamate carboxypepti ( 719) 1506 303.6 1.9e-81
XP_016872924 (OMIM: 600934) PREDICTED: glutamate c ( 704) 1495 301.4   8e-81
NP_001180401 (OMIM: 600934) glutamate carboxypepti ( 704) 1495 301.4   8e-81
XP_016872922 (OMIM: 600934) PREDICTED: glutamate c ( 774) 1495 301.5 8.6e-81
XP_016872929 (OMIM: 600934) PREDICTED: glutamate c ( 662) 1492 300.8 1.1e-80
XP_016872930 (OMIM: 600934) PREDICTED: glutamate c ( 662) 1492 300.8 1.1e-80
XP_016872927 (OMIM: 600934) PREDICTED: glutamate c ( 662) 1492 300.8 1.1e-80
XP_016872928 (OMIM: 600934) PREDICTED: glutamate c ( 662) 1492 300.8 1.1e-80
XP_011518260 (OMIM: 600934) PREDICTED: glutamate c ( 543) 1181 240.3 1.6e-62
XP_016872937 (OMIM: 600934) PREDICTED: glutamate c ( 442) 1135 231.3 6.6e-60
XP_016872935 (OMIM: 600934) PREDICTED: glutamate c ( 442) 1135 231.3 6.6e-60
XP_016872936 (OMIM: 600934) PREDICTED: glutamate c ( 442) 1135 231.3 6.6e-60
XP_016872934 (OMIM: 600934) PREDICTED: glutamate c ( 442) 1135 231.3 6.6e-60
XP_016872933 (OMIM: 600934) PREDICTED: glutamate c ( 442) 1135 231.3 6.6e-60
NP_001180402 (OMIM: 600934) glutamate carboxypepti ( 442) 1135 231.3 6.6e-60
NP_710163 (OMIM: 609020) putative N-acetylated-alp ( 442) 1134 231.1 7.6e-60
NP_001287859 (OMIM: 611636) N-acetylated-alpha-lin ( 707) 1099 224.5 1.2e-57
XP_016872533 (OMIM: 611636) PREDICTED: N-acetylate ( 742) 1099 224.5 1.3e-57
XP_016872938 (OMIM: 600934) PREDICTED: glutamate c ( 411)  904 186.4 2.1e-46
XP_016872940 (OMIM: 600934) PREDICTED: glutamate c ( 411)  904 186.4 2.1e-46
XP_016872939 (OMIM: 600934) PREDICTED: glutamate c ( 411)  904 186.4 2.1e-46
XP_016872535 (OMIM: 611636) PREDICTED: N-acetylate ( 428)  698 146.3 2.4e-34
NP_001193784 (OMIM: 604250,604720) transferrin rec ( 630)  413 91.0 1.6e-17
XP_016868062 (OMIM: 604250,604720) PREDICTED: tran ( 801)  413 91.1 1.9e-17
XP_005250610 (OMIM: 604250,604720) PREDICTED: tran ( 801)  413 91.1 1.9e-17
NP_003218 (OMIM: 604250,604720) transferrin recept ( 801)  413 91.1 1.9e-17
NP_001300895 (OMIM: 190010,616740) transferrin rec ( 478)  381 84.7 9.5e-16
NP_001300894 (OMIM: 190010,616740) transferrin rec ( 679)  381 84.8 1.2e-15
NP_001121620 (OMIM: 190010,616740) transferrin rec ( 760)  381 84.9 1.3e-15
NP_003225 (OMIM: 190010,616740) transferrin recept ( 760)  381 84.9 1.3e-15


>>NP_005459 (OMIM: 602640) N-acetylated-alpha-linked aci  (740 aa)
 initn: 4911 init1: 4911 opt: 4911  Z-score: 5161.0  bits: 965.6 E(85289):    0
Smith-Waterman score: 4911; 100.0% identity (100.0% similar) in 740 aa overlap (1-740:1-740)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 LSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 YPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE0 QAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLM
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE0 LLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQL
              670       680       690       700       710       720

              730       740
pF1KE0 SIVVTALEGAAATLRPVADL
       ::::::::::::::::::::
NP_005 SIVVTALEGAAATLRPVADL
              730       740

>>XP_011543009 (OMIM: 602640) PREDICTED: N-acetylated-al  (692 aa)
 initn: 4606 init1: 4606 opt: 4606  Z-score: 4841.0  bits: 906.3 E(85289):    0
Smith-Waterman score: 4606; 100.0% identity (100.0% similar) in 692 aa overlap (49-740:1-692)

       20        30        40        50        60        70        
pF1KE0 LGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIRENLRELSREPHLASSPRDED
                                     ::::::::::::::::::::::::::::::
XP_011                               MGQLDAHRIRENLRELSREPHLASSPRDED
                                             10        20        30

       80        90       100       110       120       130        
pF1KE0 LVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIVGPTGGIIHSCHRTEENVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIVGPTGGIIHSCHRTEENVT
               40        50        60        70        80        90

      140       150       160       170       180       190        
pF1KE0 GEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQGIKLEGTIALTRYGGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQGIKLEGTIALTRYGGVGR
              100       110       120       130       140       150

      200       210       220       230       240       250        
pF1KE0 GAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPSGVERGSYYEYFGDPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPSGVERGSYYEYFGDPLT
              160       170       180       190       200       210

      260       270       280       290       300       310        
pF1KE0 PYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAPATWQGALGCHYRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAPATWQGALGCHYRLG
              220       230       240       250       260       270

      320       330       340       350       360       370        
pF1KE0 PGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDRYVLYGNHRDSWVHGAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDRYVLYGNHRDSWVHGAVD
              280       290       300       310       320       330

      380       390       400       410       420       430        
pF1KE0 PSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERT
              340       350       360       370       380       390

      440       450       460       470       480       490        
pF1KE0 VAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGDLSIYDNWIRYFNRSSPVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGDLSIYDNWIRYFNRSSPVY
              400       410       420       430       440       450

      500       510       520       530       540       550        
pF1KE0 GLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFL
              460       470       480       490       500       510

      560       570       580       590       600       610        
pF1KE0 DPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFLQAAQQDLGALLEQHSISL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFLQAAQQDLGALLEQHSISL
              520       530       540       550       560       570

      620       630       640       650       660       670        
pF1KE0 GPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLMLLERTFLNPRAFPEERYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLMLLERTFLNPRAFPEERYY
              580       590       600       610       620       630

      680       690       700       710       720       730        
pF1KE0 SHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEGAAATLRPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEGAAATLRPVA
              640       650       660       670       680       690

      740
pF1KE0 DL
       ::
XP_011 DL
         

>>XP_011543008 (OMIM: 602640) PREDICTED: N-acetylated-al  (737 aa)
 initn: 4510 init1: 3378 opt: 4497  Z-score: 4726.0  bits: 885.1 E(85289):    0
Smith-Waterman score: 4497; 93.7% identity (95.3% similar) in 741 aa overlap (1-740:1-737)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
              430       440       450       460       470       480

              490       500       510       520        530         
pF1KE0 LSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAY-TYDRSKTSAR
       ::::::::::::::::::::::  . :  ::   : .. :   .:  .. :  : .: . 
XP_011 LSIYDNWIRYFNRSSPVYGLVPR-ARLQPGST-PPTTQPLTPLTMWTSFWTRVRRETRGI
              490       500        510        520       530        

     540       550       560       570       580       590         
pF1KE0 IYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSF
       . :  .  . :  .    :  :::::::::::::::::::::::::::::::::::::::
XP_011 LRPGQER-LKTEPW-PCHLAAGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSF
      540        550        560       570       580       590      

     600       610       620       630       640       650         
pF1KE0 LQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQL
        600       610       620       630       640       650      

     660       670       680       690       700       710         
pF1KE0 MLLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQ
        660       670       680       690       700       710      

     720       730       740
pF1KE0 LSIVVTALEGAAATLRPVADL
       :::::::::::::::::::::
XP_011 LSIVVTALEGAAATLRPVADL
        720       730       

>>XP_011543011 (OMIM: 602640) PREDICTED: N-acetylated-al  (547 aa)
 initn: 3605 init1: 3605 opt: 3605  Z-score: 3790.6  bits: 711.6 E(85289): 2.1e-204
Smith-Waterman score: 3605; 98.7% identity (99.8% similar) in 542 aa overlap (1-542:1-542)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 LSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::.... :.
XP_011 LSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRASAAIRL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 YPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFL
       .:                                                          
XP_011 WPGQRGV                                                     
                                                                   

>>XP_011543012 (OMIM: 602640) PREDICTED: N-acetylated-al  (522 aa)
 initn: 3382 init1: 3382 opt: 3387  Z-score: 3561.8  bits: 669.2 E(85289): 1.2e-191
Smith-Waterman score: 3387; 98.6% identity (98.8% similar) in 513 aa overlap (1-512:1-513)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
              430       440       450       460       470       480

              490       500        510       520       530         
pF1KE0 LSIYDNWIRYFNRSSPVYGLVPSLGS-LGAGSDYAPFVHFLGISSMDIAYTYDRSKTSAR
       :::::::::::::::::::::: : .  : : :                           
XP_011 LSIYDNWIRYFNRSSPVYGLVPRLQQPSGCGPDSGECDSPAQ                  
              490       500       510       520                    

     540       550       560       570       580       590         
pF1KE0 IYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSF

>>XP_011543014 (OMIM: 602640) PREDICTED: N-acetylated-al  (508 aa)
 initn: 3020 init1: 3020 opt: 3035  Z-score: 3192.1  bits: 600.7 E(85289): 4.6e-171
Smith-Waterman score: 3035; 92.6% identity (94.4% similar) in 499 aa overlap (1-496:1-497)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450         460       470        
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANAT--LRVQGTPPVQSVVFSATKEIRSPGP
       :::::::::::::::::::::::::::::   :   : .    .. :.      .: :::
XP_011 IGSTEFTEEFFNKLQERTVAYINVDISVFDPLTRPWRPEHLRQLDPVLQPQQPGVR-PGP
              430       440       450       460       470          

      480       490        500       510       520       530       
pF1KE0 GDLSIYDNWIRYFN-RSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTS
        .:..   : :  . :: :                                         
XP_011 -QLGFSGCWQRLCTLRSLPGHLLHGHCLYL                              
      480       490       500                                      

>>XP_011543013 (OMIM: 602640) PREDICTED: N-acetylated-al  (508 aa)
 initn: 3020 init1: 3020 opt: 3035  Z-score: 3192.1  bits: 600.7 E(85289): 4.6e-171
Smith-Waterman score: 3035; 92.6% identity (94.4% similar) in 499 aa overlap (1-496:1-497)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450         460       470        
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANAT--LRVQGTPPVQSVVFSATKEIRSPGP
       :::::::::::::::::::::::::::::   :   : .    .. :.      .: :::
XP_011 IGSTEFTEEFFNKLQERTVAYINVDISVFDPLTRPWRPEHLRQLDPVLQPQQPGVR-PGP
              430       440       450       460       470          

      480       490        500       510       520       530       
pF1KE0 GDLSIYDNWIRYFN-RSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTS
        .:..   : :  . :: :                                         
XP_011 -QLGFSGCWQRLCTLRSLPGHLLHGHCLYL                              
      480       490       500                                      

>>XP_011543010 (OMIM: 602640) PREDICTED: N-acetylated-al  (687 aa)
 initn: 4335 init1: 3020 opt: 3024  Z-score: 3178.7  bits: 598.7 E(85289): 2.6e-170
Smith-Waterman score: 4246; 90.3% identity (91.1% similar) in 740 aa overlap (1-740:1-687)

               10        20        30        40        50        60
pF1KE0 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIREN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 IGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGD
       :::::::::::::::::::::::::::::           :.       :.  :   :  
XP_011 IGSTEFTEEFFNKLQERTVAYINVDISVF----------DPL-------TRPWR---PEH
              430       440                 450                 460

              490       500       510       520       530       540
pF1KE0 LSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARI
       :   :          ::  : :.  ..  :    :                 .:::::::
XP_011 LRQLD----------PV--LQPQQPGVRPG----P-----------------QSKTSARI
                          470                            480       

              550       560       570       580       590       600
pF1KE0 YPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFL
       490       500       510       520       530       540       

              610       620       630       640       650       660
pF1KE0 QAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQLM
       550       560       570       580       590       600       

              670       680       690       700       710       720
pF1KE0 LLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQL
       610       620       630       640       650       660       

              730       740
pF1KE0 SIVVTALEGAAATLRPVADL
       ::::::::::::::::::::
XP_011 SIVVTALEGAAATLRPVADL
       670       680       

>>NP_004467 (OMIM: 600934) glutamate carboxypeptidase 2   (750 aa)
 initn: 952 init1: 535 opt: 1737  Z-score: 1825.9  bits: 348.5 E(85289): 5.8e-95
Smith-Waterman score: 1740; 38.3% identity (70.3% similar) in 751 aa overlap (2-738:19-750)

                                10        20        30         40  
pF1KE0                  MQWTKVLGLGLGAAALLGLGIILGHFAIPK-KANSLAPQDLDL
                         .:  . .: : :.... ::...: :   . .:....:.    
NP_004 MWNLLHETDSAVATARRPRWLCAGALVL-AGGFFLLGFLFGWFIKSSNEATNITPK----
               10        20         30        40        50         

             50        60        70        80        90       100  
pF1KE0 EILETVMGQLDAHRIRENLRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTY
       . ... . .: :. :.. : .... ::::.. .. .:.. . ..::  : ::::.: . :
NP_004 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWK--EFGLDSVELAHY
          60        70        80        90       100         110   

            110       120       130       140       150       160  
pF1KE0 EVLLSFPSQEQPNVVDIVGPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGL
       .::::.:.. .:: ..:..  :. : .    :    : ..  :.: :..:..:.: :.: 
NP_004 DVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGD
           120       130       140       150       160       170   

            170       180        190       200       210       220 
pF1KE0 LVYANRGAEEDFKELQTQ-GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPAD
       :::.: .  ::: .:. .  :.  : :...::: : :: :. ::   :. ::..:.::::
NP_004 LVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPAD
           180       190       200       210       220       230   

              230       240       250         260       270        
pF1KE0 -INDGLSSPDETFPNSWYLPPSGVERGSYYEY--FGDPLTPYLPAVPSSFRVDLANVSGF
        .  :..:    .:..: :: .::.::.  .    ::::::  ::   ..:  .:.. :.
NP_004 YFAPGVKS----YPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGL
           240           250       260       270       280         

      280       290       300        310       320       330       
pF1KE0 PPIPTQPIGFQDARDLLCNLNGTLAP-ATWQGALGCHYRLGPGFRPDGDFPADSQVNVSV
       : ::..:::. ::. :: ...:.  : ..:.:.:   : .::::   :.: . ..:.. .
NP_004 PSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGF--TGNF-STQKVKMHI
     290       300       310       320       330          340      

       340       350       360       370       380       390       
pF1KE0 YNRLELRNSSNVLGIIRGAVEPDRYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLL
       ..  :.    ::.: .::::::::::. :.:::::: :..::.::.::. :. : .::: 
NP_004 HSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLK
        350       360       370       380       390       400      

       400       410       420       430       440       450       
pF1KE0 KKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQ
       :.: :::::.:.:::: ::::::.::::..::    :::: :::::.: :. .: ::::.
NP_004 KEG-WRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVD
         410       420       430       440       450       460     

       460       470         480       490       500       510     
pF1KE0 GTPPVQSVVFSATKEIRSPGPG--DLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAP
        :: . :.: . :::..::  :    :.:..: .  .  :: .. .: ...::.:.:.  
NP_004 CTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTK--KSPSPEFSGMPRISKLGSGNDFEV
         470       480       490         500       510       520   

         520       530       540       550       560       570     
pF1KE0 FVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSV
       : . :::.:    :: .   ..   :: ::....:.. :.:: :: :. : .::.. :..
NP_004 FFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGM
           530       540       550       560       570       580   

         580       590          600       610       620       630  
pF1KE0 ILRLSDSFFLPLKVSDYSETLRSF---LQAAQQDLGALLEQHSISLGPLVTAVEKFEAEA
       ...:..:. ::.   ::. .::..   . . ..     .. .:.:.  : .::..:   :
NP_004 VFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIA
           590       600       610       620       630       640   

            640       650       660       670       680       690  
pF1KE0 AALGQRISTLQKGSPDPLQVRMLNDQLMLLERTFLNPRAFPEERYYSHVLWAPRTGSVV-
       . ...:.. ..:.  .:. .::.:::::.:::.:..: ..:.. .: ::..:: . .   
NP_004 SKFSERLQDFDKS--NPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYA
           650         660       670       680       690       700 

               700       710       720       730       740
pF1KE0 --TFPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEGAAATLRPVADL
         .:::. .:    .. .. :.::.::.::. ... ....:: ::  ::  
NP_004 GESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA  
             710       720       730       740       750  

>>XP_016872923 (OMIM: 600934) PREDICTED: glutamate carbo  (735 aa)
 initn: 952 init1: 535 opt: 1726  Z-score: 1814.4  bits: 346.4 E(85289): 2.5e-94
Smith-Waterman score: 1728; 38.8% identity (69.9% similar) in 745 aa overlap (9-738:9-735)

               10         20        30         40        50        
pF1KE0 MQWTKVLGLGLGAAALLG-LGIILGHFAIPK-KANSLAPQDLDLEILETVMGQLDAHRIR
               : :.: :  : :.  :: :   . .:....:.    . ... . .: :. :.
XP_016 MTAGSSYPLFLAAYACTGCLAERLGWFIKSSNEATNITPK----HNMKAFLDELKAENIK
               10        20        30        40            50      

       60        70        80        90       100       110        
pF1KE0 ENLRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVD
       . : .... ::::.. .. .:.. . ..::  : ::::.: . :.::::.:.. .:: ..
XP_016 KFLYNFTQIPHLAGTEQNFQLAKQIQSQWK--EFGLDSVELAHYDVLLSYPNKTHPNYIS
         60        70        80          90       100       110    

      120       130       140       150       160       170        
pF1KE0 IVGPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQ
       :..  :. : .    :    : ..  :.: :..:..:.: :.: :::.: .  ::: .:.
XP_016 IINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLE
          120       130       140       150       160       170    

      180        190       200       210       220        230      
pF1KE0 TQ-GIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPAD-INDGLSSPDETFPNS
        .  :.  : :...::: : :: :. ::   :. ::..:.:::: .  :..:    .:..
XP_016 RDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKS----YPDG
          180       190       200       210       220           230

        240       250         260       270       280       290    
pF1KE0 WYLPPSGVERGSYYEY--FGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDL
       : :: .::.::.  .    ::::::  ::   ..:  .:.. :.: ::..:::. ::. :
XP_016 WNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKL
              240       250       260       270       280       290

          300        310       320       330       340       350   
pF1KE0 LCNLNGTLAP-ATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGII
       : ...:.  : ..:.:.:   : .::::   :.: . ..:.. ...  :.    ::.: .
XP_016 LEKMGGSAPPDSSWRGSLKVPYNVGPGFT--GNF-STQKVKMHIHSTNEVTRIYNVIGTL
              300       310         320        330       340       

           360       370       380       390       400       410   
pF1KE0 RGAVEPDRYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASW
       ::::::::::. :.:::::: :..::.::.::. :. : .::: :.: :::::.:.::::
XP_016 RGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEG-WRPRRTILFASW
       350       360       370       380       390        400      

           420       430       440       450       460       470   
pF1KE0 GAEEFGLIGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEI
        ::::::.::::..::    :::: :::::.: :. .: ::::. :: . :.: . :::.
XP_016 DAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKEL
        410       420       430       440       450       460      

             480       490       500       510       520       530 
pF1KE0 RSPGPG--DLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTY
       .::  :    :.:..: .  .  :: .. .: ...::.:.:.  : . :::.:    :: 
XP_016 KSPDEGFEGKSLYESWTK--KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTK
        470       480         490       500       510       520    

             540       550       560       570       580       590 
pF1KE0 DRSKTSARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSD
       .   ..   :: ::....:.. :.:: :: :. : .::.. :.....:..:. ::.   :
XP_016 NWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRD
          530       540       550       560       570       580    

                600       610       620       630       640        
pF1KE0 YSETLRSF---LQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPD
       :. .::..   . . ..     .. .:.:.  : .::..:   :. ...:.. ..:.  .
XP_016 YAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS--N
          590       600       610       620       630       640    

      650       660       670       680       690          700     
pF1KE0 PLQVRMLNDQLMLLERTFLNPRAFPEERYYSHVLWAPRTGSVV---TFPGLSNACSRARD
       :. .::.:::::.:::.:..: ..:.. .: ::..:: . .     .:::. .:    ..
XP_016 PIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIES
            650       660       670       680       690       700  

         710       720       730       740
pF1KE0 TASGSEAWAEVQRQLSIVVTALEGAAATLRPVADL
        .. :.::.::.::. ... ....:: ::  ::  
XP_016 KVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA  
            710       720       730       




740 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:45:20 2016 done: Fri Nov  4 06:45:22 2016
 Total Scan time: 12.920 Total Display time:  0.200

Function used was FASTA [36.3.4 Apr, 2011]
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