FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0042, 511 aa 1>>>pF1KE0042 511 - 511 aa - 511 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7004+/-0.000318; mu= 12.2600+/- 0.020 mean_var=104.4994+/-20.422, 0's: 0 Z-trim(118.6): 91 B-trim: 62 in 1/55 Lambda= 0.125463 statistics sampled from 31537 (31628) to 31537 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.371), width: 16 Scan time: 10.580 The best scores are: opt bits E(85289) NP_001243625 (OMIM: 616347) PR domain-containing p ( 477) 3264 601.3 2.1e-171 XP_011518533 (OMIM: 616347) PREDICTED: PR domain-c ( 477) 3264 601.3 2.1e-171 XP_011518526 (OMIM: 616347) PREDICTED: PR domain-c (1177) 3116 574.7 5.2e-163 XP_011518524 (OMIM: 616347) PREDICTED: PR domain-c (1177) 3116 574.7 5.2e-163 XP_011518525 (OMIM: 616347) PREDICTED: PR domain-c (1177) 3116 574.7 5.2e-163 XP_011518527 (OMIM: 616347) PREDICTED: PR domain-c (1177) 3116 574.7 5.2e-163 NP_001243624 (OMIM: 616347) PR domain-containing p (1177) 3116 574.7 5.2e-163 XP_011518528 (OMIM: 616347) PREDICTED: PR domain-c ( 994) 1838 343.3 1.9e-93 XP_011518529 (OMIM: 616347) PREDICTED: PR domain-c ( 994) 1838 343.3 1.9e-93 XP_011518530 (OMIM: 616347) PREDICTED: PR domain-c ( 968) 1721 322.1 4.5e-87 XP_011518532 (OMIM: 616347) PREDICTED: PR domain-c ( 516) 1297 245.2 3.4e-64 XP_016878371 (OMIM: 609759) PREDICTED: probable hi ( 419) 531 106.5 1.5e-22 XP_016878372 (OMIM: 609759) PREDICTED: probable hi ( 419) 531 106.5 1.5e-22 XP_016878373 (OMIM: 609759) PREDICTED: probable hi ( 313) 529 106.1 1.6e-22 XP_005256331 (OMIM: 609759) PREDICTED: probable hi ( 492) 531 106.6 1.8e-22 NP_001091643 (OMIM: 609759) probable histone-lysin ( 492) 531 106.6 1.8e-22 NP_064612 (OMIM: 609760) histone-lysine N-methyltr ( 894) 535 107.4 1.8e-22 NP_001297143 (OMIM: 609760) histone-lysine N-methy ( 894) 535 107.4 1.8e-22 XP_011521131 (OMIM: 609759) PREDICTED: probable hi ( 377) 367 76.8 1.2e-13 XP_011534365 (OMIM: 603423) PREDICTED: PR domain z ( 789) 317 68.0 1.2e-10 XP_016866676 (OMIM: 603423) PREDICTED: PR domain z ( 789) 317 68.0 1.2e-10 XP_006715613 (OMIM: 603423) PREDICTED: PR domain z ( 796) 317 68.0 1.2e-10 NP_001189 (OMIM: 603423) PR domain zinc finger pro ( 825) 317 68.0 1.2e-10 XP_011534364 (OMIM: 603423) PREDICTED: PR domain z ( 839) 317 68.0 1.3e-10 NP_036538 (OMIM: 605780) PR domain zinc finger pro ( 801) 303 65.4 7.1e-10 NP_078780 (OMIM: 611781) PR domain zinc finger pro ( 571) 248 55.4 5.3e-07 XP_011542028 (OMIM: 616982,617039) PREDICTED: puta ( 395) 230 52.0 3.7e-06 NP_001129711 (OMIM: 616982,617039) putative histon ( 595) 230 52.1 5.2e-06 NP_878911 (OMIM: 603423) PR domain zinc finger pro ( 691) 231 52.4 5.2e-06 XP_016857753 (OMIM: 601196) PREDICTED: PR domain z ( 310) 225 51.1 5.6e-06 NP_001129082 (OMIM: 601196) PR domain zinc finger ( 226) 213 48.8 2e-05 XP_011515874 (OMIM: 611781) PREDICTED: PR domain z ( 316) 212 48.7 2.9e-05 XP_016857746 (OMIM: 601196) PREDICTED: PR domain z (1682) 223 51.1 3e-05 NP_056950 (OMIM: 601196) PR domain zinc finger pro (1682) 223 51.1 3e-05 NP_036363 (OMIM: 601196) PR domain zinc finger pro (1718) 223 51.1 3.1e-05 XP_016857745 (OMIM: 601196) PREDICTED: PR domain z (1718) 223 51.1 3.1e-05 XP_016857744 (OMIM: 601196) PREDICTED: PR domain z (1718) 223 51.1 3.1e-05 XP_005247283 (OMIM: 165215,616738) PREDICTED: MDS1 ( 906) 210 48.6 9.1e-05 XP_016861366 (OMIM: 165215,616738) PREDICTED: MDS1 ( 907) 210 48.6 9.1e-05 XP_005247282 (OMIM: 165215,616738) PREDICTED: MDS1 ( 915) 210 48.6 9.2e-05 XP_005247281 (OMIM: 165215,616738) PREDICTED: MDS1 ( 916) 210 48.6 9.2e-05 XP_005247272 (OMIM: 165215,616738) PREDICTED: MDS1 (1230) 210 48.7 0.00012 XP_005247271 (OMIM: 165215,616738) PREDICTED: MDS1 (1231) 210 48.7 0.00012 NP_004982 (OMIM: 165215,616738) MDS1 and EVI1 comp (1239) 210 48.7 0.00012 XP_005247270 (OMIM: 165215,616738) PREDICTED: MDS1 (1240) 210 48.7 0.00012 XP_005268650 (OMIM: 605780) PREDICTED: PR domain z ( 808) 192 45.3 0.00079 XP_016857743 (OMIM: 601196) PREDICTED: PR domain z (1608) 180 43.3 0.0064 XP_011534366 (OMIM: 603423) PREDICTED: PR domain z ( 667) 174 42.0 0.0065 XP_016857742 (OMIM: 601196) PREDICTED: PR domain z (1644) 180 43.3 0.0065 >>NP_001243625 (OMIM: 616347) PR domain-containing prote (477 aa) initn: 3264 init1: 3264 opt: 3264 Z-score: 3198.3 bits: 601.3 E(85289): 2.1e-171 Smith-Waterman score: 3264; 100.0% identity (100.0% similar) in 477 aa overlap (35-511:1-477) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: NP_001 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG ::::::::::::::::::::::::::: NP_001 EFSDPAGKLVWMRLLSEGRVRSGLCGG 460 470 >>XP_011518533 (OMIM: 616347) PREDICTED: PR domain-conta (477 aa) initn: 3264 init1: 3264 opt: 3264 Z-score: 3198.3 bits: 601.3 E(85289): 2.1e-171 Smith-Waterman score: 3264; 100.0% identity (100.0% similar) in 477 aa overlap (35-511:1-477) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: XP_011 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG ::::::::::::::::::::::::::: XP_011 EFSDPAGKLVWMRLLSEGRVRSGLCGG 460 470 >>XP_011518526 (OMIM: 616347) PREDICTED: PR domain-conta (1177 aa) initn: 3116 init1: 3116 opt: 3116 Z-score: 3047.6 bits: 574.7 E(85289): 5.2e-163 Smith-Waterman score: 3116; 100.0% identity (100.0% similar) in 456 aa overlap (35-490:1-456) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: XP_011 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG :::::: XP_011 EFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQE 460 470 480 490 500 510 >>XP_011518524 (OMIM: 616347) PREDICTED: PR domain-conta (1177 aa) initn: 3116 init1: 3116 opt: 3116 Z-score: 3047.6 bits: 574.7 E(85289): 5.2e-163 Smith-Waterman score: 3116; 100.0% identity (100.0% similar) in 456 aa overlap (35-490:1-456) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: XP_011 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG :::::: XP_011 EFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQE 460 470 480 490 500 510 >>XP_011518525 (OMIM: 616347) PREDICTED: PR domain-conta (1177 aa) initn: 3116 init1: 3116 opt: 3116 Z-score: 3047.6 bits: 574.7 E(85289): 5.2e-163 Smith-Waterman score: 3116; 100.0% identity (100.0% similar) in 456 aa overlap (35-490:1-456) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: XP_011 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG :::::: XP_011 EFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQE 460 470 480 490 500 510 >>XP_011518527 (OMIM: 616347) PREDICTED: PR domain-conta (1177 aa) initn: 3116 init1: 3116 opt: 3116 Z-score: 3047.6 bits: 574.7 E(85289): 5.2e-163 Smith-Waterman score: 3116; 100.0% identity (100.0% similar) in 456 aa overlap (35-490:1-456) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: XP_011 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG :::::: XP_011 EFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQE 460 470 480 490 500 510 >>NP_001243624 (OMIM: 616347) PR domain-containing prote (1177 aa) initn: 3116 init1: 3116 opt: 3116 Z-score: 3047.6 bits: 574.7 E(85289): 5.2e-163 Smith-Waterman score: 3116; 100.0% identity (100.0% similar) in 456 aa overlap (35-490:1-456) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: NP_001 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP 400 410 420 430 440 450 490 500 510 pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG :::::: NP_001 EFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQE 460 470 480 490 500 510 >>XP_011518528 (OMIM: 616347) PREDICTED: PR domain-conta (994 aa) initn: 1838 init1: 1838 opt: 1838 Z-score: 1798.5 bits: 343.3 E(85289): 1.9e-93 Smith-Waterman score: 1838; 100.0% identity (100.0% similar) in 273 aa overlap (218-490:1-273) 190 200 210 220 230 240 pF1KE0 KSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACR :::::::::::::::::::::::::::::: XP_011 MRYVVISREEREQNLLAFQHSERIYFRACR 10 20 30 250 260 270 280 290 300 pF1KE0 DIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHL 40 50 60 70 80 90 310 320 330 340 350 360 pF1KE0 SVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRK 100 110 120 130 140 150 370 380 390 400 410 420 pF1KE0 VPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSP 160 170 180 190 200 210 430 440 450 460 470 480 pF1KE0 AEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFS 220 230 240 250 260 270 490 500 510 pF1KE0 DPAGKLVWMRLLSEGRVRSGLCGG ::: XP_011 DPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQEWLK 280 290 300 310 320 330 >>XP_011518529 (OMIM: 616347) PREDICTED: PR domain-conta (994 aa) initn: 1838 init1: 1838 opt: 1838 Z-score: 1798.5 bits: 343.3 E(85289): 1.9e-93 Smith-Waterman score: 1838; 100.0% identity (100.0% similar) in 273 aa overlap (218-490:1-273) 190 200 210 220 230 240 pF1KE0 KSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACR :::::::::::::::::::::::::::::: XP_011 MRYVVISREEREQNLLAFQHSERIYFRACR 10 20 30 250 260 270 280 290 300 pF1KE0 DIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHL 40 50 60 70 80 90 310 320 330 340 350 360 pF1KE0 SVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRK 100 110 120 130 140 150 370 380 390 400 410 420 pF1KE0 VPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSP 160 170 180 190 200 210 430 440 450 460 470 480 pF1KE0 AEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFS 220 230 240 250 260 270 490 500 510 pF1KE0 DPAGKLVWMRLLSEGRVRSGLCGG ::: XP_011 DPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQEWLK 280 290 300 310 320 330 >>XP_011518530 (OMIM: 616347) PREDICTED: PR domain-conta (968 aa) initn: 1721 init1: 1721 opt: 1721 Z-score: 1684.2 bits: 322.1 E(85289): 4.5e-87 Smith-Waterman score: 1721; 98.0% identity (99.2% similar) in 252 aa overlap (35-286:1-252) 10 20 30 40 50 60 pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP :::::::::::::::::::::::::::::: XP_011 MTENMKECLAQTNAAVGDMVTVVKTEVCSP 10 20 30 70 80 90 100 110 120 pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP :::::::::::::::::::::::::::::::::::::. . . XP_011 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARASESMVSGPAIMEDDDQEVDSAD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV XP_011 ESVSNDMMTATDEPSKMSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQS 280 290 300 310 320 330 511 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:24:50 2016 done: Fri Nov 4 06:24:52 2016 Total Scan time: 10.580 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]