FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0048, 522 aa 1>>>pF1KE0048 522 - 522 aa - 522 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9580+/-0.000884; mu= 8.2283+/- 0.054 mean_var=176.2150+/-34.948, 0's: 0 Z-trim(112.8): 32 B-trim: 0 in 0/53 Lambda= 0.096617 statistics sampled from 13443 (13468) to 13443 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.414), width: 16 Scan time: 3.730 The best scores are: opt bits E(32554) CCDS3738.1 LARP1B gene_id:55132|Hs108|chr4 ( 914) 3449 493.0 6e-139 CCDS64057.1 LARP1B gene_id:55132|Hs108|chr4 ( 335) 2253 326.0 4.3e-89 CCDS47133.1 LARP1B gene_id:55132|Hs108|chr4 ( 358) 2253 326.0 4.5e-89 CCDS4328.1 LARP1 gene_id:23367|Hs108|chr5 (1019) 1560 229.7 1.2e-59 >>CCDS3738.1 LARP1B gene_id:55132|Hs108|chr4 (914 aa) initn: 3449 init1: 3449 opt: 3449 Z-score: 2608.0 bits: 493.0 E(32554): 6e-139 Smith-Waterman score: 3449; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508) 10 20 30 40 50 60 pF1KE0 MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 EDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 WKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 WKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 ERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 KMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 PPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSETSILQAMSRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 PPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSETSILQAMSRGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 STSLPDLDSEPWIEVKKRHQPAPVKLRESVSVPEGSLNQLCSSEEPEQEELDFLFDEEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 STSLPDLDSEPWIEVKKRHQPAPVKLRESVSVPEGSLNQLCSSEEPEQEELDFLFDEEIE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 QIGRKNTFTDWSDNDSDYEIDDQDLNKILIVTQTPPYVKKHPGGDRTGTHMSRAKITSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS37 QIGRKNTFTDWSDNDSDYEIDDQDLNKILIVTQTPPYVKKHPGGDRTGTHMSRAKITSEL 430 440 450 460 470 480 490 500 510 520 pF1KE0 AKVINDGLYYYEQDLWMEEDENKHTAIKVIVSGQHLSTDALF :::::::::::::::::::::::::::: CCDS37 AKVINDGLYYYEQDLWMEEDENKHTAIKQEVENFKKLNLISKEQFENLTPELPFEPNQEV 490 500 510 520 530 540 >>CCDS64057.1 LARP1B gene_id:55132|Hs108|chr4 (335 aa) initn: 2253 init1: 2253 opt: 2253 Z-score: 1713.1 bits: 326.0 E(32554): 4.3e-89 Smith-Waterman score: 2253; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KE0 MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 EDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 WKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 WKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 ERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 KMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 PPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSETSILQAMSRGL ::::::::::::::::::::::::::::: CCDS64 PPRSVPPTDFSQLIDCPEFVPGQAFCSHTVRVMIF 310 320 330 >>CCDS47133.1 LARP1B gene_id:55132|Hs108|chr4 (358 aa) initn: 2253 init1: 2253 opt: 2253 Z-score: 1712.7 bits: 326.0 E(32554): 4.5e-89 Smith-Waterman score: 2253; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KE0 MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 WKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 WKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 KMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 PPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSETSILQAMSRGL ::::::::::::::::::::::::::::: CCDS47 PPRSVPPTDFSQLIDCPEFVPGQAFCSHTGNIFSSRANDVTVGYLVQFTYLFIYFQFI 310 320 330 340 350 >>CCDS4328.1 LARP1 gene_id:23367|Hs108|chr5 (1019 aa) initn: 1368 init1: 484 opt: 1560 Z-score: 1184.3 bits: 229.7 E(32554): 1.2e-59 Smith-Waterman score: 1739; 52.6% identity (76.8% similar) in 534 aa overlap (3-508:98-626) 10 20 30 pF1KE0 MENWPTPSELVNTGFQ--SVLSQGNKKPQNRK :::::.:... . : : : ..: .: CCDS43 PEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKK 70 80 90 100 110 120 40 50 60 70 80 pF1KE0 EKEEKVEKRSNSDSKENRETKLNGPGENVSEDE-AQSSNQRKRANKHKWVPLHLDVVRSE . .:. :: .:::::. .:: . ::. . :: : ..:.:..::::::::..:. CCDS43 DMKEQ-EKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEV 130 140 150 160 170 180 90 100 110 120 130 pF1KE0 SQERPGSRNSSRCQPE---ANKPTHNNRRNDTR--------SWK---RDREKRDDQDDVS .:. .:: . .:. ::. .. .. : .:. . . :::..: CCDS43 PREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAWQPEIKPEPAWHDQDETS 190 200 210 220 230 240 140 150 160 170 180 190 pF1KE0 SVRSEG-GNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTS ::.:.: :. :.::::::::::::::::::. : .:::..::.. . .. : . .. CCDS43 SVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFDYQFGYRKF-DGVEGPRTPKYMNN 250 260 270 280 290 300 200 210 220 230 240 250 pF1KE0 MMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIA . ::.:. .....: :.. :::.::::::::::::.::::::::: ::: .:::::.::: CCDS43 ITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIA 310 320 330 340 350 360 260 270 280 290 300 310 pF1KE0 GFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGPPPRSVPPTDFSQLI .:.:::::::...::. ::::: :::::::.:.. ::::::.: : . ::::::. CCDS43 SFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREEPEKWPLP--PIVDYSQTDFSQLL 370 380 390 400 410 420 320 330 340 350 360 370 pF1KE0 DCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSETSILQAMSRGLSTSLPDLDSEPWIE .:::::: : . ..:::::.::: .:. : :. :.: :... .:::.:::::::: ::: CCDS43 NCPEFVPRQHYQKETESAPGSPRAVTPV-PTKTEEVSNLKTLPKGLSASLPDLDSENWIE 430 440 450 460 470 480 380 390 400 410 420 pF1KE0 VKKRHQPAPVKLRES--------VSVPEG-SLNQLCSSEEPEQEELDFLFDEEIEQI-GR :::: .:.:.. ..: .:.:. .:: :... ::::::::::::.::. :: CCDS43 VKKRPRPSPARPKKSEESRFSHLTSLPQQLPSQQLMSKDQDEQEELDFLFDEEMEQMDGR 490 500 510 520 530 540 430 440 450 460 470 480 pF1KE0 KNTFTDWSDNDSDYEIDDQDLNKILIVTQTPPYVKKHPGGDRTGTHMSRAKITSELAKVI ::::: :::..:::::::.:.:::::::::: :...::::::::.: ::::...:::::: CCDS43 KNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGGDRTGNHTSRAKMSAELAKVI 550 560 570 580 590 600 490 500 510 520 pF1KE0 NDGLYYYEQDLWMEEDENKHTAIKVIVSGQHLSTDALF ::::.::::::: :. : ... :: CCDS43 NDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQFDTLTPEPPVDPNQEVPPGP 610 620 630 640 650 660 522 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:08:00 2016 done: Fri Nov 4 06:08:01 2016 Total Scan time: 3.730 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]