FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0061, 937 aa 1>>>pF1KE0061 937 - 937 aa - 937 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6970+/-0.000438; mu= 10.7230+/- 0.027 mean_var=157.4435+/-32.182, 0's: 0 Z-trim(115.9): 407 B-trim: 450 in 1/52 Lambda= 0.102214 statistics sampled from 26247 (26660) to 26247 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.313), width: 16 Scan time: 14.330 The best scores are: opt bits E(85289) NP_061733 (OMIM: 606313) protocadherin alpha-7 iso ( 937) 6164 921.9 0 NP_114040 (OMIM: 606313) protocadherin alpha-7 iso ( 789) 5119 767.7 0 NP_061731 (OMIM: 606311) protocadherin alpha-5 iso ( 936) 5007 751.3 5.3e-216 NP_061726 (OMIM: 606318) protocadherin alpha-12 is ( 941) 4884 733.1 1.5e-210 NP_114063 (OMIM: 606315) protocadherin alpha-9 iso ( 950) 4505 677.2 1e-193 NP_054724 (OMIM: 606315) protocadherin alpha-9 iso ( 842) 4486 674.4 6.5e-193 NP_061730 (OMIM: 606310) protocadherin alpha-4 iso ( 947) 4239 638.0 6.6e-182 NP_113688 (OMIM: 606310) protocadherin alpha-4 iso ( 798) 4220 635.2 4e-181 NP_061729 (OMIM: 606309) protocadherin alpha-3 iso ( 950) 4100 617.5 9.8e-176 NP_113685 (OMIM: 606309) protocadherin alpha-3 iso ( 824) 4076 613.9 1e-174 NP_061727 (OMIM: 606319) protocadherin alpha-13 is ( 950) 4015 605.0 5.8e-172 NP_061723 (OMIM: 606307) protocadherin alpha-1 iso ( 950) 3991 601.4 6.7e-171 NP_061732 (OMIM: 606312) protocadherin alpha-6 iso ( 950) 3989 601.1 8.3e-171 NP_114071 (OMIM: 606319) protocadherin alpha-13 is ( 807) 3987 600.8 8.9e-171 NP_114036 (OMIM: 606312) protocadherin alpha-6 iso ( 803) 3971 598.4 4.6e-170 NP_113598 (OMIM: 606307) protocadherin alpha-1 iso ( 807) 3967 597.9 6.9e-170 NP_113689 (OMIM: 606311) protocadherin alpha-5 iso ( 816) 3962 597.1 1.2e-169 NP_061734 (OMIM: 606314) protocadherin alpha-8 iso ( 950) 3956 596.3 2.4e-169 NP_114062 (OMIM: 606314) protocadherin alpha-8 iso ( 814) 3940 593.9 1.1e-168 NP_061728 (OMIM: 606308) protocadherin alpha-2 iso ( 948) 3939 593.8 1.4e-168 NP_113683 (OMIM: 606308) protocadherin alpha-2 iso ( 824) 3931 592.5 2.8e-168 NP_061725 (OMIM: 606317) protocadherin alpha-11 is ( 949) 3929 592.3 3.8e-168 NP_113684 (OMIM: 606308) protocadherin alpha-2 iso ( 808) 3927 592.0 4.1e-168 NP_061724 (OMIM: 606316) protocadherin alpha-10 is ( 948) 3911 589.6 2.4e-167 NP_114067 (OMIM: 606317) protocadherin alpha-11 is ( 810) 3909 589.3 2.6e-167 NP_114065 (OMIM: 606316) protocadherin alpha-10 is ( 844) 3901 588.1 6.1e-167 NP_114070 (OMIM: 606318) protocadherin alpha-12 is ( 792) 3867 583.1 1.9e-165 NP_113599 (OMIM: 606307) protocadherin alpha-1 iso ( 686) 2584 393.9 1.5e-108 NP_114066 (OMIM: 606316) protocadherin alpha-10 is ( 685) 2564 390.9 1.2e-107 NP_114037 (OMIM: 606312) protocadherin alpha-6 iso ( 686) 2546 388.3 7.3e-107 NP_115778 (OMIM: 603627) protocadherin gamma-C3 is ( 863) 2006 308.7 8.2e-83 NP_002579 (OMIM: 603627) protocadherin gamma-C3 is ( 934) 2006 308.7 8.7e-83 NP_114476 (OMIM: 606294) protocadherin gamma-A7 is ( 817) 1957 301.5 1.2e-80 NP_061743 (OMIM: 606294) protocadherin gamma-A7 is ( 932) 1957 301.5 1.3e-80 NP_115783 (OMIM: 606306) protocadherin gamma-C5 is ( 878) 1947 300.0 3.4e-80 NP_061752 (OMIM: 606306) protocadherin gamma-C5 is ( 944) 1947 300.0 3.6e-80 NP_115266 (OMIM: 606299) protocadherin gamma-B1 is ( 810) 1936 298.4 1e-79 NP_061745 (OMIM: 606299) protocadherin gamma-B1 is ( 927) 1936 298.4 1.1e-79 NP_114398 (OMIM: 606289) protocadherin gamma-A2 is ( 823) 1927 297.0 2.5e-79 NP_061738 (OMIM: 606289) protocadherin gamma-A2 is ( 932) 1927 297.1 2.8e-79 NP_115265 (OMIM: 603059) protocadherin gamma-A12 i ( 820) 1919 295.8 5.7e-79 NP_114479 (OMIM: 606297) protocadherin gamma-A10 i ( 850) 1919 295.9 5.9e-79 NP_003726 (OMIM: 603059) protocadherin gamma-A12 i ( 932) 1919 295.9 6.3e-79 NP_061736 (OMIM: 606297) protocadherin gamma-A10 i ( 936) 1919 295.9 6.3e-79 NP_114089 (OMIM: 606321) protocadherin alpha-C2 is ( 884) 1916 295.4 8.2e-79 NP_114442 (OMIM: 606291) protocadherin gamma-A4 is ( 851) 1894 292.2 7.6e-78 NP_061740 (OMIM: 606291) protocadherin gamma-A4 is ( 962) 1894 292.2 8.3e-78 NP_061758 (OMIM: 606341) protocadherin beta-15 pre ( 787) 1892 291.9 8.7e-78 NP_061746 (OMIM: 606300) protocadherin gamma-B2 is ( 931) 1889 291.5 1.4e-77 NP_115268 (OMIM: 606301) protocadherin gamma-B3 is ( 814) 1884 290.7 2e-77 >>NP_061733 (OMIM: 606313) protocadherin alpha-7 isoform (937 aa) initn: 6164 init1: 6164 opt: 6164 Z-score: 4921.0 bits: 921.9 E(85289): 0 Smith-Waterman score: 6164; 100.0% identity (100.0% similar) in 937 aa overlap (1-937:1-937) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 850 860 870 880 890 900 910 920 930 pF1KE0 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ ::::::::::::::::::::::::::::::::::::: NP_061 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 >>NP_114040 (OMIM: 606313) protocadherin alpha-7 isoform (789 aa) initn: 5119 init1: 5119 opt: 5119 Z-score: 4089.3 bits: 767.7 E(85289): 0 Smith-Waterman score: 5119; 100.0% identity (100.0% similar) in 785 aa overlap (1-785:1-785) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE ::::: NP_114 SSTDNVSHK >>NP_061731 (OMIM: 606311) protocadherin alpha-5 isoform (936 aa) initn: 5007 init1: 5007 opt: 5007 Z-score: 3998.9 bits: 751.3 E(85289): 5.3e-216 Smith-Waterman score: 5007; 82.7% identity (91.9% similar) in 927 aa overlap (11-937:10-936) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV : .:::. ..:: :.:: ::::::.:::::::.::::::::::::::::: NP_061 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::.. : :::::::::::::::::::::::::: : :::::::::::.::::::::. NP_061 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL : ::::::::: : .. ::: ::: ::::::::::: ::: :: : :::.::::: : NP_061 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :: :...... : ::::: :::::: : .::. :::::::::::::::::.::: ::::: NP_061 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG ::...:.:.: ::. :::::. :::: :::.: .:.: ::. : :.:::: .. .: NP_061 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP : : :..:.:. ...: ..:.::. ::.::: :.:...:::::.:....:.: ::. NP_061 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA ::: .:::.:::: ::: :.:::::::: :.:::::::::::::::::::::::::::. NP_061 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG ::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: ::::: ::::::::::::::::::::::::.:::::::::::: NP_061 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD ::::::::::::::::::::::::::.:::::::::: :::::::::::::::::::: : NP_061 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT :::::::::::::. ..: ::::::::::::::::.::::.:::::::::::::::: :: NP_061 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 600 610 620 630 640 650 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA ::::::::::::::::::::::: : .:::. :::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP ::::: .:..:. ::::.:::::::::.::::::::::::.::::::::::::::::: NP_061 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KE0 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 780 790 800 810 820 830 850 860 870 880 890 900 pF1KE0 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 840 850 860 870 880 890 910 920 930 pF1KE0 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ ::::::::::::::::::::::::::::::::::::: NP_061 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 900 910 920 930 >>NP_061726 (OMIM: 606318) protocadherin alpha-12 isofor (941 aa) initn: 3862 init1: 3862 opt: 4884 Z-score: 3900.9 bits: 733.1 E(85289): 1.5e-210 Smith-Waterman score: 4884; 80.7% identity (90.6% similar) in 942 aa overlap (1-937:3-941) 10 20 30 40 50 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAE .. : : ::...::: ...:::::.: ::::::: ::::::.::::::::::::::: NP_061 MVIIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAE 10 20 30 40 50 60 70 80 90 100 110 pF1KE0 LVPRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFH :::::::.. : .::::::::::::::::::::::.::::::::::::::::.::::::: NP_061 LVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE0 VDVEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF ::::::::::::::: .... ..:: ::::.:::::::::::: :.:::: :: :: : NP_061 VDVEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE0 FLDVPTS-NQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNND : . :. .... : ::::::::::.::.:.::: . :::::::::.::. ::::: :: NP_061 ELKIKTKKDKSILPE-LVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVND 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE0 NAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDP :.:.::. : : : :::. : ::. :::: ::::::.: :... . . : : ..: NP_061 NGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE0 LSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSL .: : . :..::::. :..: :.:.:::.: .::: :::::.:::::.:.. .::::: NP_061 DTGEIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE0 PIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRES :. :::: ::::.:::: ::: :.:::: :::::.::::::::.:::::::::::::::: NP_061 PVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRES 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE0 VSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTV :::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::: NP_061 VSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE0 SAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSA :: :::::::::::::::: ::::.::::::::::::::::::::::::::::::::::: NP_061 SAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSA 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE0 RDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAV :::::::::::::::::::::::::::::: .:..:::: ::::::::::::::::::: NP_061 RDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAV 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE0 DADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP ::::::::::::::::.:.:: :::.:::::::::::: :::.::::::::::::::::: NP_061 DADSGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEP 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE0 SLTATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLL .::.::::::::::.:::::.:::::.: . ::. :::.::::::::::::::::::::: NP_061 ALTSTATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLL 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE0 YTALRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLP ::::::::: . . :. ::::::::::::::.::::::::::.:.::::::::::::: NP_061 YTALRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQ 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE0 QGPSSTDNP----RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT . . :: ::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LSREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE0 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 840 850 860 870 880 890 900 910 920 930 pF1KE0 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::: NP_061 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 900 910 920 930 940 >>NP_114063 (OMIM: 606315) protocadherin alpha-9 isoform (950 aa) initn: 4485 init1: 4485 opt: 4505 Z-score: 3598.8 bits: 677.2 E(85289): 1e-193 Smith-Waterman score: 5493; 90.1% identity (94.6% similar) in 943 aa overlap (8-937:8-950) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV :: :. ::: ..::: : .: :::::::::::.::.::::::::::::::::: NP_114 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD ::::. : ::::::::::::::::::::::::::::::::::::::::.::::::::: NP_114 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_114 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP :::::::::::::::::::::::::::::::::::.:::::::::::::::. .::.:. NP_114 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA :::: ::::.::::.: : .::::::::::.::::::::.::::::::: ::::::::: NP_114 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG ::::::::::::::::::: ::::::::::::::::: ::::::::::::::::::::: NP_114 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: :.:::.::::::::::::::::::::::::::::::::::::: NP_114 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD ::::::::::::::::::::::::::.::. :: ::: :.: :::::: ::.:::::::: NP_114 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT ::::::::::::: .:.:::::::::::::::::::::::::::.::::::::::::.:: NP_114 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::.:::::.: .:::. :::::::::::::::::::::::::::. NP_114 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 670 680 690 700 710 720 730 740 750 760 770 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL---- ::::: .:: :. ::::::::::::::.::::::::::::: :::::::::.: NP_114 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 730 740 750 760 770 780 780 790 800 810 820 pF1KE0 --------PQGPS-STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP :.. : :: .:::::::::::::::::::::::::::::::::::::::::: NP_114 GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 830 840 850 860 870 880 pF1KE0 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 890 900 910 920 930 pF1KE0 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_054724 (OMIM: 606315) protocadherin alpha-9 isoform (842 aa) initn: 4921 init1: 4477 opt: 4486 Z-score: 3584.4 bits: 674.4 E(85289): 6.5e-193 Smith-Waterman score: 4486; 87.6% identity (94.0% similar) in 798 aa overlap (8-805:8-803) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV :: :. ::: ..::: : .: :::::::::::.::.::::::::::::::::: NP_054 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD ::::. : ::::::::::::::::::::::::::::::::::::::::.::::::::: NP_054 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_054 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP :::::::::::::::::::::::::::::::::::.:::::::::::::::. .::.:. NP_054 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA :::: ::::.::::.: : .::::::::::.::::::::.::::::::: ::::::::: NP_054 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG ::::::::::::::::::: ::::::::::::::::: ::::::::::::::::::::: NP_054 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: :.:::.::::::::::::::::::::::::::::::::::::: NP_054 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD ::::::::::::::::::::::::::.::. :: ::: :.: :::::: ::.:::::::: NP_054 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT ::::::::::::: .:.:::::::::::::::::::::::::::.::::::::::::.:: NP_054 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::.:::::.: .:::. :::::::::::::::::::::::::::. NP_054 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP ::::: .:: :. ::::::::::::::.::::::::::::: :::::::::.: .: NP_054 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL--SP 730 740 750 760 770 790 800 810 820 830 840 pF1KE0 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE . .. : .:. ... ..:. : NP_054 CAGSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIF 780 790 800 810 820 830 >>NP_061730 (OMIM: 606310) protocadherin alpha-4 isoform (947 aa) initn: 4219 init1: 4219 opt: 4239 Z-score: 3386.8 bits: 638.0 E(85289): 6.6e-182 Smith-Waterman score: 5235; 85.7% identity (92.8% similar) in 942 aa overlap (6-937:6-947) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV : .:.:::....::::::: ::::::: ::::::.::::::::::::::::: NP_061 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::.. : :: ::::::::::::::::::::::: :::::::::::::.::::::::: NP_061 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL :::.:::::::::::::.:: ::::::::::::::::::::::::::::::::::::: : NP_061 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP . : ... :: :::.::: :::::.::. :.::::::::::::::::::::::: ::::: NP_061 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG .::::.: :.: ::: :::::. :::::::::::::.::::.:.::..:::::.::..: NP_061 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP : : :..:::::....: ::..::: ::.::: :.::: : :::.:.: . :::::: NP_061 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA ::: ::::.:::: :.:.:::: :::::: .:::::::::::::::::::::::::::: NP_061 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: ::::::::::::::::::::::::::::::::::::::.:::: NP_061 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::.::::::: :::: :::.::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT ::::::::::::: ..:: ::::::::::::::::::::::::::::::::::::::.:: NP_061 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::: .: .::.. :::::::::::::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP ::::: .::::. ::::::::::::::.::::: :::::::::::::::::::::.. NP_061 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 730 740 750 760 770 780 790 800 810 820 830 pF1KE0 SSTDN----------PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS . :. ::::::::::::::::::::::::::::::::::::::::::::: NP_061 DREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE0 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 850 860 870 880 890 900 900 910 920 930 pF1KE0 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ ::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 >>NP_113688 (OMIM: 606310) protocadherin alpha-4 isoform (798 aa) initn: 4216 init1: 4216 opt: 4220 Z-score: 3372.7 bits: 635.2 E(85289): 4e-181 Smith-Waterman score: 4220; 84.1% identity (92.6% similar) in 779 aa overlap (6-784:6-784) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV : .:.:::....::::::: ::::::: ::::::.::::::::::::::::: NP_113 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::.. : :: ::::::::::::::::::::::: :::::::::::::.::::::::: NP_113 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL :::.:::::::::::::.:: ::::::::::::::::::::::::::::::::::::: : NP_113 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP . : ... :: :::.::: :::::.::. :.::::::::::::::::::::::: ::::: NP_113 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG .::::.: :.: ::: :::::. :::::::::::::.::::.:.::..:::::.::..: NP_113 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP : : :..:::::....: ::..::: ::.::: :.::: : :::.:.: . :::::: NP_113 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA ::: ::::.:::: :.:.:::: :::::: .:::::::::::::::::::::::::::: NP_113 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: ::::::::::::::::::::::::::::::::::::::.:::: NP_113 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD :::::::::::::::::::::::::::::.::::::: :::: :::.::::::::::::: NP_113 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT ::::::::::::: ..:: ::::::::::::::::::::::::::::::::::::::.:: NP_113 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA :::::::::::::::::::::: .: .::.. :::::::::::::::::::::::::::: NP_113 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP ::::: .::::. ::::::::::::::.::::: :::::::::::::::::::::.. NP_113 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE . : NP_113 DREDQLQTTEESFAKVSV 790 >>NP_061729 (OMIM: 606309) protocadherin alpha-3 isoform (950 aa) initn: 4078 init1: 4078 opt: 4100 Z-score: 3276.0 bits: 617.5 E(85289): 9.8e-176 Smith-Waterman score: 5074; 82.9% identity (91.4% similar) in 943 aa overlap (8-937:8-950) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV :::.. ::: ...::: :.: ::::::: ::::::.::::::::::::::::: NP_061 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::.. : .:::::::::::::::::::::::::::::::::::::::.::::::::. NP_061 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL ::::::::: :::: . .::::.::: ::: :::::::::: :.:::: :. .::: : NP_061 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :: .....: :::::.: :.::.::. .::.:: ::::::::::.:: ::::: ::::: NP_061 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG .:.::.: :.: ::. ::::. ::.:::::.: :: :::..:.: :: ::::.::..: NP_061 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP :.: :..:::::....: :::.::: ::.. :::::.:.::.:::.:.:.. :::::. NP_061 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA ::. .:::.:::: ::: ::::::::::::.::::::::::::::::::: :::::::: NP_061 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG :::::::::::::::::::::::::::::::::::.: ::::::::::::::::::::: NP_061 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: ::::::::::::::::::::::::::::::::::::::::::: NP_061 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD :::::::::::::::::::::::::: ::::: :::: :::::::::::::::::::::: NP_061 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT ::::::::::::: ..:: ::::::::::::::::::::.:::::::::::::::::::: NP_061 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA ::::::::::::::::::::.:: : .:::. :::::::::.:::::::::::::::::: NP_061 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP :::::: .:: :. ::::::::::::::.::::.:::::::: ::::::::::::: : NP_061 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 730 740 750 760 770 780 790 800 810 820 pF1KE0 SSTD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP : : .:::::::::::::::::::::::::::::::::::::::::: NP_061 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 790 800 810 820 830 840 830 840 850 860 870 880 pF1KE0 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 850 860 870 880 890 900 890 900 910 920 930 pF1KE0 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 910 920 930 940 950 >>NP_113685 (OMIM: 606309) protocadherin alpha-3 isoform (824 aa) initn: 4522 init1: 4076 opt: 4076 Z-score: 3257.8 bits: 613.9 E(85289): 1e-174 Smith-Waterman score: 4076; 79.9% identity (90.5% similar) in 792 aa overlap (8-799:8-799) 10 20 30 40 50 60 pF1KE0 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV :::.. ::: ...::: :.: ::::::: ::::::.::::::::::::::::: NP_113 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD :::::.. : .:::::::::::::::::::::::::::::::::::::::.::::::::. NP_113 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL ::::::::: :::: . .::::.::: ::: :::::::::: :.:::: :. .::: : NP_113 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP :: .....: :::::.: :.::.::. .::.:: ::::::::::.:: ::::: ::::: NP_113 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG .:.::.: :.: ::. ::::. ::.:::::.: :: :::..:.: :: ::::.::..: NP_113 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP :.: :..:::::....: :::.::: ::.. :::::.:.::.:::.:.:.. :::::. NP_113 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA ::. .:::.:::: ::: ::::::::::::.::::::::::::::::::: :::::::: NP_113 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG :::::::::::::::::::::::::::::::::::.: ::::::::::::::::::::: NP_113 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA :::::.:::::::::: ::::::::::::::::::::::::::::::::::::::::::: NP_113 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD :::::::::::::::::::::::::: ::::: :::: :::::::::::::::::::::: NP_113 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT ::::::::::::: ..:: ::::::::::::::::::::.:::::::::::::::::::: NP_113 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA ::::::::::::::::::::.:: : .:::. :::::::::.:::::::::::::::::: NP_113 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP :::::: .:: :. ::::::::::::::.::::.:::::::: ::::::::::::: : NP_113 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE : : .. . : ::.. NP_113 ISRDREEKQDVDVDLSAKVSNFYLFFPKCLCFSFLNVSTPLEIH 790 800 810 820 937 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:24:01 2016 done: Fri Nov 4 05:24:03 2016 Total Scan time: 14.330 Total Display time: 0.360 Function used was FASTA [36.3.4 Apr, 2011]