FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0064, 579 aa 1>>>pF1KE0064 579 - 579 aa - 579 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.0102+/-0.000456; mu= -9.3521+/- 0.028 mean_var=554.2511+/-116.235, 0's: 0 Z-trim(124.0): 70 B-trim: 760 in 1/58 Lambda= 0.054478 statistics sampled from 44717 (44832) to 44717 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.526), width: 16 Scan time: 12.660 The best scores are: opt bits E(85289) NP_001020402 (OMIM: 613260) keratinocyte proline-r ( 579) 4419 362.2 2.7e-99 XP_011507873 (OMIM: 613260) PREDICTED: keratinocyt ( 579) 4419 362.2 2.7e-99 >>NP_001020402 (OMIM: 613260) keratinocyte proline-rich (579 aa) initn: 4419 init1: 4419 opt: 4419 Z-score: 1903.6 bits: 362.2 E(85289): 2.7e-99 Smith-Waterman score: 4419; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579) 10 20 30 40 50 60 pF1KE0 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 490 500 510 520 530 540 550 560 570 pF1KE0 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF ::::::::::::::::::::::::::::::::::::::: NP_001 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF 550 560 570 >>XP_011507873 (OMIM: 613260) PREDICTED: keratinocyte pr (579 aa) initn: 4419 init1: 4419 opt: 4419 Z-score: 1903.6 bits: 362.2 E(85289): 2.7e-99 Smith-Waterman score: 4419; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579) 10 20 30 40 50 60 pF1KE0 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 490 500 510 520 530 540 550 560 570 pF1KE0 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF ::::::::::::::::::::::::::::::::::::::: XP_011 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF 550 560 570 579 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:19:44 2016 done: Fri Nov 4 05:19:46 2016 Total Scan time: 12.660 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]