FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0072, 1340 aa 1>>>pF1KE0072 1340 - 1340 aa - 1340 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2871+/-0.000509; mu= 2.8072+/- 0.031 mean_var=187.7096+/-40.464, 0's: 0 Z-trim(113.3): 413 B-trim: 217 in 1/56 Lambda= 0.093612 statistics sampled from 22118 (22558) to 22118 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.264), width: 16 Scan time: 16.500 The best scores are: opt bits E(85289) NP_116755 (OMIM: 400022) protocadherin-11 Y-linked (1340) 8774 1199.1 0 XP_016885569 (OMIM: 400022) PREDICTED: protocadher (1329) 8651 1182.5 0 XP_016885568 (OMIM: 400022) PREDICTED: protocadher (1329) 8651 1182.5 0 XP_016885570 (OMIM: 400022) PREDICTED: protocadher (1329) 8651 1182.5 0 XP_016884908 (OMIM: 300246) PREDICTED: protocadher (1308) 8392 1147.5 0 NP_001161834 (OMIM: 300246) protocadherin-11 X-lin (1310) 8378 1145.6 0 XP_016884909 (OMIM: 300246) PREDICTED: protocadher (1339) 8378 1145.6 0 NP_116754 (OMIM: 400022) protocadherin-11 Y-linked (1048) 6751 925.8 0 NP_116751 (OMIM: 300246) protocadherin-11 X-linked (1337) 6659 913.4 0 XP_016884907 (OMIM: 300246) PREDICTED: protocadher (1366) 6659 913.4 0 NP_001161835 (OMIM: 300246) protocadherin-11 X-lin (1329) 6656 913.0 0 XP_011529215 (OMIM: 300246) PREDICTED: protocadher (1358) 6656 913.0 0 NP_001161832 (OMIM: 300246) protocadherin-11 X-lin (1339) 6654 912.8 0 XP_011529214 (OMIM: 300246) PREDICTED: protocadher (1368) 6654 912.8 0 XP_011529216 (OMIM: 300246) PREDICTED: protocadher (1347) 6646 911.7 0 NP_116750 (OMIM: 300246) protocadherin-11 X-linked (1347) 6646 911.7 0 XP_011529213 (OMIM: 300246) PREDICTED: protocadher (1376) 6646 911.7 0 XP_016884906 (OMIM: 300246) PREDICTED: protocadher (1376) 6646 911.7 0 XP_011529212 (OMIM: 300246) PREDICTED: protocadher (1376) 6646 911.7 0 XP_016884905 (OMIM: 300246) PREDICTED: protocadher (1345) 6637 910.5 0 XP_016885571 (OMIM: 400022) PREDICTED: protocadher (1037) 6628 909.2 0 NP_001265548 (OMIM: 400022) protocadherin-11 Y-lin (1037) 6628 909.2 0 NP_116753 (OMIM: 400022) protocadherin-11 Y-linked (1037) 6628 909.2 0 XP_016884911 (OMIM: 300246) PREDICTED: protocadher (1025) 6419 881.0 0 XP_011529218 (OMIM: 300246) PREDICTED: protocadher (1054) 6419 881.0 0 XP_011529217 (OMIM: 300246) PREDICTED: protocadher (1054) 6419 881.0 0 NP_001161833 (OMIM: 300246) protocadherin-11 X-lin (1065) 6416 880.6 0 XP_016884910 (OMIM: 300246) PREDICTED: protocadher (1076) 6416 880.6 0 XP_016885572 (OMIM: 400022) PREDICTED: protocadher ( 956) 6177 848.3 0 NP_065136 (OMIM: 603581) protocadherin-9 isoform 2 (1203) 4356 602.4 6.3e-171 NP_001305302 (OMIM: 603581) protocadherin-9 isofor (1161) 3964 549.4 5.3e-155 XP_016876108 (OMIM: 603581) PREDICTED: protocadher (1237) 3957 548.5 1.1e-154 NP_982354 (OMIM: 603581) protocadherin-9 isoform 1 (1237) 3957 548.5 1.1e-154 NP_001305301 (OMIM: 603581) protocadherin-9 isofor (1195) 3955 548.2 1.3e-154 XP_011533401 (OMIM: 603581) PREDICTED: protocadher (1054) 3952 547.8 1.5e-154 XP_016876109 (OMIM: 603581) PREDICTED: protocadher (1066) 3941 546.3 4.2e-154 XP_016876110 (OMIM: 603581) PREDICTED: protocadher (1019) 3936 545.6 6.5e-154 XP_005266465 (OMIM: 603581) PREDICTED: protocadher (1019) 3936 545.6 6.5e-154 NP_001305303 (OMIM: 603581) protocadherin-9 isofor (1032) 3935 545.5 7.2e-154 NP_073754 (OMIM: 614449) protocadherin-20 precurso ( 951) 2007 285.1 1.6e-75 XP_016876197 (OMIM: 614449) PREDICTED: protocadher ( 951) 2007 285.1 1.6e-75 XP_016863749 (OMIM: 602988) PREDICTED: protocadher (1286) 1493 215.7 1.7e-54 XP_016863750 (OMIM: 602988) PREDICTED: protocadher (1285) 1490 215.3 2.2e-54 XP_005248220 (OMIM: 602988) PREDICTED: protocadher (1275) 1485 214.7 3.5e-54 XP_016863751 (OMIM: 602988) PREDICTED: protocadher (1277) 1484 214.5 3.8e-54 XP_016863748 (OMIM: 602988) PREDICTED: protocadher (1288) 1484 214.5 3.9e-54 XP_011512145 (OMIM: 602988) PREDICTED: protocadher (1276) 1423 206.3 1.2e-51 XP_016863757 (OMIM: 602988) PREDICTED: protocadher (1182) 1400 203.2 9.4e-51 XP_005248221 (OMIM: 602988) PREDICTED: protocadher (1267) 1399 203.0 1.1e-50 XP_016863756 (OMIM: 602988) PREDICTED: protocadher (1190) 1398 202.9 1.1e-50 >>NP_116755 (OMIM: 400022) protocadherin-11 Y-linked iso (1340 aa) initn: 8774 init1: 8774 opt: 8774 Z-score: 6413.6 bits: 1199.1 E(85289): 0 Smith-Waterman score: 8774; 100.0% identity (100.0% similar) in 1340 aa overlap (1-1340:1-1340) 10 20 30 40 50 60 pF1KE0 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA 1270 1280 1290 1300 1310 1320 1330 1340 pF1KE0 PRQQARPSRGDSPIMETHPL :::::::::::::::::::: NP_116 PRQQARPSRGDSPIMETHPL 1330 1340 >>XP_016885569 (OMIM: 400022) PREDICTED: protocadherin-1 (1329 aa) initn: 8651 init1: 8651 opt: 8651 Z-score: 6323.8 bits: 1182.5 E(85289): 0 Smith-Waterman score: 8651; 100.0% identity (100.0% similar) in 1319 aa overlap (22-1340:11-1329) 10 20 30 40 50 60 pF1KE0 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY ::::::::::::::::::::::::::::::::::::::: XP_016 MTVGFNSDISSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 10 20 30 40 70 80 90 100 110 120 pF1KE0 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE0 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE0 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE0 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 590 600 610 620 630 640 670 680 690 700 710 720 pF1KE0 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 650 660 670 680 690 700 730 740 750 760 770 780 pF1KE0 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 710 720 730 740 750 760 790 800 810 820 830 840 pF1KE0 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 770 780 790 800 810 820 850 860 870 880 890 900 pF1KE0 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 830 840 850 860 870 880 910 920 930 940 950 960 pF1KE0 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KE0 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KE0 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KE0 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KE0 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KE0 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KE0 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA 1250 1260 1270 1280 1290 1300 1330 1340 pF1KE0 PRQQARPSRGDSPIMETHPL :::::::::::::::::::: XP_016 PRQQARPSRGDSPIMETHPL 1310 1320 >>XP_016885568 (OMIM: 400022) PREDICTED: protocadherin-1 (1329 aa) initn: 8651 init1: 8651 opt: 8651 Z-score: 6323.8 bits: 1182.5 E(85289): 0 Smith-Waterman score: 8651; 100.0% identity (100.0% similar) in 1319 aa overlap (22-1340:11-1329) 10 20 30 40 50 60 pF1KE0 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY ::::::::::::::::::::::::::::::::::::::: XP_016 MTVGFNSDISSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 10 20 30 40 70 80 90 100 110 120 pF1KE0 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE0 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE0 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE0 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 590 600 610 620 630 640 670 680 690 700 710 720 pF1KE0 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 650 660 670 680 690 700 730 740 750 760 770 780 pF1KE0 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 710 720 730 740 750 760 790 800 810 820 830 840 pF1KE0 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 770 780 790 800 810 820 850 860 870 880 890 900 pF1KE0 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 830 840 850 860 870 880 910 920 930 940 950 960 pF1KE0 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KE0 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KE0 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KE0 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KE0 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KE0 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KE0 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA 1250 1260 1270 1280 1290 1300 1330 1340 pF1KE0 PRQQARPSRGDSPIMETHPL :::::::::::::::::::: XP_016 PRQQARPSRGDSPIMETHPL 1310 1320 >>XP_016885570 (OMIM: 400022) PREDICTED: protocadherin-1 (1329 aa) initn: 8651 init1: 8651 opt: 8651 Z-score: 6323.8 bits: 1182.5 E(85289): 0 Smith-Waterman score: 8651; 100.0% identity (100.0% similar) in 1319 aa overlap (22-1340:11-1329) 10 20 30 40 50 60 pF1KE0 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY ::::::::::::::::::::::::::::::::::::::: XP_016 MTVGFNSDISSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 10 20 30 40 70 80 90 100 110 120 pF1KE0 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE0 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE0 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE0 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE0 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE0 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE0 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE0 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE0 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE0 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 590 600 610 620 630 640 670 680 690 700 710 720 pF1KE0 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 650 660 670 680 690 700 730 740 750 760 770 780 pF1KE0 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 710 720 730 740 750 760 790 800 810 820 830 840 pF1KE0 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 770 780 790 800 810 820 850 860 870 880 890 900 pF1KE0 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 830 840 850 860 870 880 910 920 930 940 950 960 pF1KE0 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KE0 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KE0 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KE0 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KE0 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KE0 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KE0 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA 1250 1260 1270 1280 1290 1300 1330 1340 pF1KE0 PRQQARPSRGDSPIMETHPL :::::::::::::::::::: XP_016 PRQQARPSRGDSPIMETHPL 1310 1320 >>XP_016884908 (OMIM: 300246) PREDICTED: protocadherin-1 (1308 aa) initn: 8392 init1: 8392 opt: 8392 Z-score: 6134.9 bits: 1147.5 E(85289): 0 Smith-Waterman score: 8392; 98.2% identity (99.1% similar) in 1306 aa overlap (35-1340:3-1308) 10 20 30 40 50 60 pF1KE0 GFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIRE ::::::::::::.::::::::::::::::: XP_016 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIRE 10 20 30 70 80 90 100 110 120 pF1KE0 EIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID :.:::::::.:::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 NGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAML :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 NGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAML 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE0 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE ::::::::::::::::::::::::::::::::: :::: ::::::::.:::::::::::: XP_016 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE0 FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 520 530 540 550 560 570 610 620 630 640 650 660 pF1KE0 NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD 580 590 600 610 620 630 670 680 690 700 710 720 pF1KE0 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPG ::::::::::::::::::::::::::::::::::::::::::::: : :::::::::::: XP_016 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPG 640 650 660 670 680 690 730 740 750 760 770 780 pF1KE0 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KE0 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVK ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVK 760 770 780 790 800 810 850 860 870 880 890 900 pF1KE0 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKK :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKK 820 830 840 850 860 870 910 920 930 940 950 960 pF1KE0 KKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KE0 PDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVS ::::::::::::::::::::::::: :::::::::::::::::::::.:::::::::::: XP_016 PDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVS 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KE0 DCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGY 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KE0 PQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDA 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KE0 CWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIALCHSP :::::::::::::::::::::::::::::::::::: :::::.::::::::::::::::: XP_016 CWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSP 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KE0 PPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIALHRSQ ::::::::::::::::.::::::::::::::::::::::::::::::: ::::::::::: XP_016 PPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQ 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KE0 AQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFAPRQQ :::::::::::::::.:::::::::::::::::::::::::::::::::::::::.:::: XP_016 AQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQ 1240 1250 1260 1270 1280 1290 1330 1340 pF1KE0 ARPSRGDSPIMETHPL :::::::::::: ::: XP_016 ARPSRGDSPIMEEHPL 1300 >>NP_001161834 (OMIM: 300246) protocadherin-11 X-linked (1310 aa) initn: 8040 init1: 6914 opt: 8378 Z-score: 6124.7 bits: 1145.6 E(85289): 0 Smith-Waterman score: 8378; 98.0% identity (98.9% similar) in 1308 aa overlap (35-1340:3-1310) 10 20 30 40 50 60 pF1KE0 GFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIRE ::::::::::::.::::::::::::::::: NP_001 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIRE 10 20 30 70 80 90 100 110 120 pF1KE0 EIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID :.:::::::.:::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 NGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAML :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 NGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAML 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE0 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE ::::::::::::::::::::::::::::::::: :::: ::::::::.:::::::::::: NP_001 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE0 FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 520 530 540 550 560 570 610 620 630 640 650 660 pF1KE0 NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD 580 590 600 610 620 630 670 680 690 700 710 720 pF1KE0 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPG ::::::::::::::::::::::::::::::::::::::::::::: : :::::::::::: NP_001 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPG 640 650 660 670 680 690 730 740 750 760 770 780 pF1KE0 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KE0 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVK ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVK 760 770 780 790 800 810 850 860 870 880 890 900 pF1KE0 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKK :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKK 820 830 840 850 860 870 910 920 930 940 950 960 pF1KE0 KKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KE0 PDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVS ::::::::::::::::::::::::: :::::::::::::::::::::.:::::::::::: NP_001 PDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVS 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KE0 DCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGY 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KE0 PQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK--EITVQPTVEEASDNCTQECLIYGHS ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 PQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHS 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KE0 DACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIALCH :::::::::::::::::::::::::::::::::::::: :::::.::::::::::::::: NP_001 DACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCH 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KE0 SPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIALHR ::::::::::::::::::.::::::::::::::::::::::::::::::: ::::::::: NP_001 SPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHR 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KE0 SQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFAPR :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::.:: NP_001 SQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPR 1240 1250 1260 1270 1280 1290 1330 1340 pF1KE0 QQARPSRGDSPIMETHPL :::::::::::::: ::: NP_001 QQARPSRGDSPIMEEHPL 1300 1310 >>XP_016884909 (OMIM: 300246) PREDICTED: protocadherin-1 (1339 aa) initn: 8040 init1: 6914 opt: 8378 Z-score: 6124.5 bits: 1145.6 E(85289): 0 Smith-Waterman score: 8378; 98.0% identity (98.9% similar) in 1308 aa overlap (35-1340:32-1339) 10 20 30 40 50 60 pF1KE0 GFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIRE ::::::::::::.::::::::::::::::: XP_016 RTERQWVLIQIFQVLCGLIQQTVTSVPGMDLLSGTYIFAVLLACVVFHSGAQEKNYTIRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID :.:::::::.:::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 NGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAML :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 NGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAML 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE ::::::::::::::::::::::::::::::::: :::: ::::::::.:::::::::::: XP_016 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPG ::::::::::::::::::::::::::::::::::::::::::::: : :::::::::::: XP_016 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVK ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKK :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 KKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 PDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVS ::::::::::::::::::::::::: :::::::::::::::::::::.:::::::::::: XP_016 PDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 DCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGY 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 PQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK--EITVQPTVEEASDNCTQECLIYGHS ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 PQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 DACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIALCH :::::::::::::::::::::::::::::::::::::: :::::.::::::::::::::: XP_016 DACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCH 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 SPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIALHR ::::::::::::::::::.::::::::::::::::::::::::::::::: ::::::::: XP_016 SPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFAPR :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::.:: XP_016 SQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPR 1270 1280 1290 1300 1310 1320 1330 1340 pF1KE0 QQARPSRGDSPIMETHPL :::::::::::::: ::: XP_016 QQARPSRGDSPIMEEHPL 1330 >>NP_116754 (OMIM: 400022) protocadherin-11 Y-linked iso (1048 aa) initn: 7308 init1: 6751 opt: 6751 Z-score: 4938.7 bits: 925.8 E(85289): 0 Smith-Waterman score: 6751; 99.7% identity (99.9% similar) in 1047 aa overlap (1-1047:1-1047) 10 20 30 40 50 60 pF1KE0 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL :::::::::::::::::::::::.. : NP_116 YSVSDCGYPVTTFEVPVSVHTRPTDSRT 1030 1040 >>NP_116751 (OMIM: 300246) protocadherin-11 X-linked iso (1337 aa) initn: 7881 init1: 6416 opt: 6659 Z-score: 4869.9 bits: 913.4 E(85289): 0 Smith-Waterman score: 8314; 96.0% identity (96.9% similar) in 1335 aa overlap (35-1340:3-1337) 10 20 30 40 50 60 pF1KE0 GFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIRE ::::::::::::.::::::::::::::::: NP_116 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIRE 10 20 30 70 80 90 100 110 120 pF1KE0 EIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID :.:::::::.:::::::::::::::::.:::::::::::::::::::::::::::::::: NP_116 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE0 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE0 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE0 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE0 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE0 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE0 NGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAML :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_116 NGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAML 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE0 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE ::::::::::::::::::::::::::::::::: :::: ::::::::.:::::::::::: NP_116 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE0 FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 520 530 540 550 560 570 610 620 630 640 650 660 pF1KE0 NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD 580 590 600 610 620 630 670 680 690 700 710 720 pF1KE0 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPG ::::::::::::::::::::::::::::::::::::::::::::: : :::::::::::: NP_116 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPG 640 650 660 670 680 690 730 740 750 760 770 780 pF1KE0 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KE0 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVK ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_116 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVK 760 770 780 790 800 810 850 860 870 880 890 900 pF1KE0 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKK :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_116 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKK 820 830 840 850 860 870 910 920 930 940 950 960 pF1KE0 KKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_116 KKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KE0 PDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVS ::::::::::::::::::::::::: :::::::::::::::::::::.:::::::::::: NP_116 PDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVS 940 950 960 970 980 990 1030 1040 1050 pF1KE0 DCGYPVTTFEVPVSVHTRP---------------------------SQRRVTFHLPEGSQ ::::::::::::::::::: :::::::::::::: NP_116 DCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQSQRRVTFHLPEGSQ 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 pF1KE0 ESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 ESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KE0 --EITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 AAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQAST 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KE0 QHHSPPVTQTIVLCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASA ::::: :::::.:::::::::::::::::::::::::::::::::.:::::::::::::: NP_116 QHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASA 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 pF1KE0 LCYSPPLAQAAAISHSSSLPQVIALHRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATS ::::::::::::::::: ::::::::::::::::::::::::::.::::::::::::::: NP_116 LCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATS 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 pF1KE0 QFYTMSERLHPSDDSIKVIPLTTFAPRQQARPSRGDSPIMETHPL ::::::::::::::::::::::::.:::::::::::::::: ::: NP_116 QFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL 1300 1310 1320 1330 >>XP_016884907 (OMIM: 300246) PREDICTED: protocadherin-1 (1366 aa) initn: 7881 init1: 6416 opt: 6659 Z-score: 4869.7 bits: 913.4 E(85289): 0 Smith-Waterman score: 8314; 96.0% identity (96.9% similar) in 1335 aa overlap (35-1340:32-1366) 10 20 30 40 50 60 pF1KE0 GFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIRE ::::::::::::.::::::::::::::::: XP_016 RTERQWVLIQIFQVLCGLIQQTVTSVPGMDLLSGTYIFAVLLACVVFHSGAQEKNYTIRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 EIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID :.:::::::.:::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARID 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 NGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAML :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 NGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAML 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE ::::::::::::::::::::::::::::::::: :::: ::::::::.:::::::::::: XP_016 FIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPG ::::::::::::::::::::::::::::::::::::::::::::: : :::::::::::: XP_016 REKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVK ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 ANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKK :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 ILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 KKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 PDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVS ::::::::::::::::::::::::: :::::::::::::::::::::.:::::::::::: XP_016 PDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVS 970 980 990 1000 1010 1020 1030 1040 1050 pF1KE0 DCGYPVTTFEVPVSVHTRP---------------------------SQRRVTFHLPEGSQ ::::::::::::::::::: :::::::::::::: XP_016 DCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQSQRRVTFHLPEGSQ 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KE0 ESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KE0 --EITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQAST 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KE0 QHHSPPVTQTIVLCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASA ::::: :::::.:::::::::::::::::::::::::::::::::.:::::::::::::: XP_016 QHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASA 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KE0 LCYSPPLAQAAAISHSSSLPQVIALHRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATS ::::::::::::::::: ::::::::::::::::::::::::::.::::::::::::::: XP_016 LCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATS 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 pF1KE0 QFYTMSERLHPSDDSIKVIPLTTFAPRQQARPSRGDSPIMETHPL ::::::::::::::::::::::::.:::::::::::::::: ::: XP_016 QFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL 1330 1340 1350 1360 1340 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:17:00 2016 done: Fri Nov 4 04:17:02 2016 Total Scan time: 16.500 Total Display time: 0.840 Function used was FASTA [36.3.4 Apr, 2011]