FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0079, 616 aa 1>>>pF1KE0079 616 - 616 aa - 616 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4479+/-0.000836; mu= 10.8891+/- 0.050 mean_var=165.7703+/-31.942, 0's: 0 Z-trim(113.5): 38 B-trim: 22 in 1/51 Lambda= 0.099614 statistics sampled from 14108 (14143) to 14108 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.434), width: 16 Scan time: 3.130 The best scores are: opt bits E(32554) CCDS11980.1 TNFRSF11A gene_id:8792|Hs108|chr18 ( 616) 4380 641.6 9e-184 CCDS74227.1 TNFRSF11A gene_id:8792|Hs108|chr18 ( 263) 1888 283.1 3.1e-76 CCDS74228.1 TNFRSF11A gene_id:8792|Hs108|chr18 ( 337) 1763 265.3 9.5e-71 CCDS59324.1 TNFRSF11A gene_id:8792|Hs108|chr18 ( 299) 1502 227.7 1.7e-59 CCDS13393.1 CD40 gene_id:958|Hs108|chr20 ( 277) 548 90.6 3e-18 CCDS13394.1 CD40 gene_id:958|Hs108|chr20 ( 203) 483 81.1 1.5e-15 CCDS59233.1 LTBR gene_id:4055|Hs108|chr12 ( 416) 405 70.2 6.2e-12 CCDS8544.1 LTBR gene_id:4055|Hs108|chr12 ( 435) 405 70.2 6.4e-12 CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 ( 461) 397 69.1 1.5e-11 CCDS6326.1 TNFRSF11B gene_id:4982|Hs108|chr8 ( 401) 383 67.0 5.4e-11 >>CCDS11980.1 TNFRSF11A gene_id:8792|Hs108|chr18 (616 aa) initn: 4380 init1: 4380 opt: 4380 Z-score: 3412.8 bits: 641.6 E(32554): 9e-184 Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE 550 560 570 580 590 600 610 pF1KE0 PEKASRPVQEQGGAKA :::::::::::::::: CCDS11 PEKASRPVQEQGGAKA 610 >>CCDS74227.1 TNFRSF11A gene_id:8792|Hs108|chr18 (263 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1482.2 bits: 283.1 E(32554): 3.1e-76 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 262 aa overlap (1-262:1-262) 10 20 30 40 50 60 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC :::::::::::::::::::::: CCDS74 ALTANLWHWINEACGRLSGDKEM 250 260 >>CCDS74228.1 TNFRSF11A gene_id:8792|Hs108|chr18 (337 aa) initn: 1750 init1: 1750 opt: 1763 Z-score: 1383.7 bits: 265.3 E(32554): 9.5e-71 Smith-Waterman score: 1804; 54.7% identity (54.7% similar) in 616 aa overlap (1-616:1-337) 10 20 30 40 50 60 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC ::: CCDS74 ALT--------------------------------------------------------- 310 320 330 340 350 360 pF1KE0 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL CCDS74 ------------------------------------------------------------ 370 380 390 400 410 420 pF1KE0 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN CCDS74 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KE0 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP CCDS74 ------------------------------------------------------------ 490 500 510 520 530 540 pF1KE0 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM :::::::::::::::::: CCDS74 ------------------------------------------GNVTGNSNSTFISSGQVM 250 260 550 560 570 580 590 600 pF1KE0 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE 270 280 290 300 310 320 610 pF1KE0 PEKASRPVQEQGGAKA :::::::::::::::: CCDS74 PEKASRPVQEQGGAKA 330 >>CCDS59324.1 TNFRSF11A gene_id:8792|Hs108|chr18 (299 aa) initn: 1502 init1: 1502 opt: 1502 Z-score: 1181.7 bits: 227.7 E(32554): 1.7e-59 Smith-Waterman score: 1502; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK ::::::::::::::::::::::::: CCDS59 RVEHHGTEKSDAVCSSSLPARKPPNGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQE 190 200 210 220 230 240 >-- initn: 630 init1: 630 opt: 630 Z-score: 504.4 bits: 102.4 E(32554): 9e-22 Smith-Waterman score: 630; 100.0% identity (100.0% similar) in 94 aa overlap (523-616:206-299) 500 510 520 530 540 550 pF1KE0 PEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVS :::::::::::::::::::::::::::::: CCDS59 TFLGKRVEHHGTEKSDAVCSSSLPARKPPNGNVTGNSNSTFISSGQVMNFKGDIIVVYVS 180 190 200 210 220 230 560 570 580 590 600 610 pF1KE0 QTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQG 240 250 260 270 280 290 pF1KE0 GAKA :::: CCDS59 GAKA >>CCDS13393.1 CD40 gene_id:958|Hs108|chr20 (277 aa) initn: 525 init1: 287 opt: 548 Z-score: 441.1 bits: 90.6 E(32554): 3e-18 Smith-Waterman score: 548; 37.7% identity (63.6% similar) in 231 aa overlap (14-241:4-226) 10 20 30 40 50 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPP--CTSEKHYEHLGRCCNKCEPGKYMSS : : :.: . : .:.. :: : ::.: ..::. :.::. . : CCDS13 MVRLPLQCVLWGCLLTAVHPEPPTACR-EKQYLINSQCCSLCQPGQKLVS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGY :: ... ::::: .:.::.::.: .: :: :: . .: . :.: : :.: :. CCDS13 DCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGW 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 H-WSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTF : :. :: : . :.::.:... .::.:.:: .:.::.. :. .::.:::.: CCDS13 HCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCET 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 LGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRK :.. ::.:.:.::. . : : .: .:. .::: . :: ..: : . CCDS13 KDLVVQQAGTNKTDVVCGPQDRLRA-----LVVIP-IIFGILFA-ILLVLVFIKKVAKKP 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE0 KGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPE .:: CCDS13 TNKAPHPKQEPQEINFPDDLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ 230 240 250 260 270 >>CCDS13394.1 CD40 gene_id:958|Hs108|chr20 (203 aa) initn: 491 init1: 287 opt: 483 Z-score: 392.4 bits: 81.1 E(32554): 1.5e-15 Smith-Waterman score: 483; 40.5% identity (66.9% similar) in 163 aa overlap (14-173:4-165) 10 20 30 40 50 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPP--CTSEKHYEHLGRCCNKCEPGKYMSS : : :.: . : .:.. :: : ::.: ..::. :.::. . : CCDS13 MVRLPLQCVLWGCLLTAVHPEPPTACR-EKQYLINSQCCSLCQPGQKLVS 10 20 30 40 60 70 80 90 100 110 pF1KE0 KCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGY :: ... ::::: .:.::.::.: .: :: :: . .: . :.: : :.: :. CCDS13 DCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGW 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 H-WSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTF : :. :: : . :.::.:... .::.:.:: .:.::.. :. .::.::: CCDS13 HCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTRSPG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 LGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRK CCDS13 SAESPGGDPHHLRDPVCHPLGAGLYQKGGQEANQ 170 180 190 200 >>CCDS59233.1 LTBR gene_id:4055|Hs108|chr12 (416 aa) initn: 314 init1: 182 opt: 405 Z-score: 327.7 bits: 70.2 E(32554): 6.2e-12 Smith-Waterman score: 406; 30.3% identity (55.5% similar) in 238 aa overlap (24-246:6-239) 10 20 30 40 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQI-APPCTSE---------KHYEHLGR-CCNK ...: :. .:: .:: ..:: : ::.. CCDS59 MEATGISLASQLKVPPYASENQTCRDQEKEYYEPQHRICCSR 10 20 30 40 50 60 70 80 90 100 pF1KE0 CEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTP : :: :.:.::. :.:: :. . : . :: : : . :: .: .. .: CCDS59 CPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRK 50 60 70 80 90 100 110 120 130 140 150 160 pF1KE0 RRCACTAGYH---WSQDCECCRRNTECAPGLGAQHPLQLNK-DTVCKPCLAGYFSDAFSS .: : :. :. .: :. ..: :: :. ...: .. : :: ::.:... : CCDS59 TQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSP 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE0 TDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVAL . .:.: : : : :: .::..:.. : ::. ..: .. .:: . : CCDS59 SARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPL-PPEMSGTML--MLAVLLPLAFFL 170 180 190 200 210 230 240 250 260 270 280 pF1KE0 VAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGV . : .:. : :. .: .: CCDS59 LLATVFS-CIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPI 220 230 240 250 260 270 >>CCDS8544.1 LTBR gene_id:4055|Hs108|chr12 (435 aa) initn: 314 init1: 182 opt: 405 Z-score: 327.5 bits: 70.2 E(32554): 6.4e-12 Smith-Waterman score: 416; 31.5% identity (54.6% similar) in 251 aa overlap (10-246:16-258) 10 20 30 40 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSE---------KHYEHLGR :: .: : .::: : : .:: .:: ..:: : CCDS85 MLLPWATSAPGLAWGPL--VLGLFGLLAASQP--QAVPPYASENQTCRDQEKEYYEPQHR 10 20 30 40 50 50 60 70 80 90 100 pF1KE0 -CCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAG ::..: :: :.:.::. :.:: :. . : . :: : : . :: .: .. CCDS85 ICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPC 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE0 NSTTPRRCACTAGYH---WSQDCECCRRNTECAPGLGAQHPLQLNK-DTVCKPCLAGYFS .: .: : :. :. .: :. ..: :: :. ...: .. : :: ::.:. CCDS85 TSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQ 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 DAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLF .. : . .:.: : : : :: .::..:.. : ::. ..: .. .:: CCDS85 NTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPL-PPEMSGTML--MLAVLLP 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 ASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQG . :. : .:. : :. .: .: CCDS85 LAFFLLLATVFS-CIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQ 240 250 260 270 280 290 >>CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 (461 aa) initn: 337 init1: 161 opt: 397 Z-score: 320.9 bits: 69.1 E(32554): 1.5e-11 Smith-Waterman score: 397; 33.5% identity (57.1% similar) in 203 aa overlap (17-212:23-219) 10 20 30 40 50 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGR-CCNKCEPG : : .: : . . : ...:.. .. ::.:: :: CCDS14 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE0 KYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCL-LHKVCDTGKALVAVVAGNSTTPRRC .. . :: :::.:: : . : . :: .:: . :.. . : . : . : : CCDS14 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQ--VETQACTREQNRIC 70 80 90 100 110 120 130 140 150 160 pF1KE0 ACTAGYH----WSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDK .: :.. .. :. : .: ::.:. .: ..:.::::: : ::.. :::: CCDS14 TCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDI 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 CRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARK-PPNEPHVYLPGLIILLLFASVALVA ::: :. : :. . ::::.:. :.:. :. :. : CCDS14 CRPHQICNV----VAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 AIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLL CCDS14 TAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCL 240 250 260 270 280 290 >>CCDS6326.1 TNFRSF11B gene_id:4982|Hs108|chr8 (401 aa) initn: 319 init1: 169 opt: 383 Z-score: 310.8 bits: 67.0 E(32554): 5.4e-11 Smith-Waterman score: 383; 34.6% identity (55.5% similar) in 191 aa overlap (16-197:4-188) 10 20 30 40 50 pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGR------CCNKCEPGK ::: :. :..... . : .: : . :.:: :: CCDS63 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGT 10 20 30 40 60 70 80 90 100 110 pF1KE0 YMSSKCTTTSDSVCLPCGPDEYL-DSWNEEDKCLL-HKVCDTGKALVAVVAG-NSTTPRR :....::. .:: :: ::.: :::. :.:: :: : : : : : : CCDS63 YLKQHCTAKWKTVCAPC-PDHYYTDSWHTSDECLYCSPVC---KELQYVKQECNRTHNRV 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE0 CACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRP : : : . . : : .. : ::.:. . ...:::: : :.::. :: :: CCDS63 CECKEGRYL--EIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE0 WTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIF :::. .: . ..:. : .::.. CCDS63 HTNCSVFGLLLTQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSV 170 180 190 200 210 220 616 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:59:08 2016 done: Fri Nov 4 03:59:09 2016 Total Scan time: 3.130 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]