Result of FASTA (omim) for
pF1KE0079
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0079, 616 aa
1>>>pF1KE0079 616 - 616 aa - 616 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0033+/-0.00034; mu= 7.4436+/- 0.021
mean_var=176.8699+/-35.163, 0's: 0 Z-trim(120.7): 93 B-trim: 115 in 1/54
Lambda= 0.096438
statistics sampled from 36109 (36206) to 36109 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.425), width: 16
Scan time: 11.600
The best scores are: opt bits E(85289)
NP_003830 (OMIM: 174810,602080,603499,612301) tumo ( 616) 4380 621.8 2.1e-177
XP_011524546 (OMIM: 174810,602080,603499,612301) P ( 621) 4360 619.0 1.5e-176
XP_016881554 (OMIM: 174810,602080,603499,612301) P ( 566) 3967 564.3 4e-160
XP_016881555 (OMIM: 174810,602080,603499,612301) P ( 546) 3321 474.4 4.4e-133
XP_016881553 (OMIM: 174810,602080,603499,612301) P ( 580) 3321 474.4 4.6e-133
XP_011524547 (OMIM: 174810,602080,603499,612301) P ( 580) 3321 474.4 4.6e-133
NP_001265197 (OMIM: 174810,602080,603499,612301) t ( 602) 3241 463.3 1.1e-129
NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 1888 274.8 2.6e-73
NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 1763 257.5 5.4e-68
NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 1502 221.2 4.2e-57
NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 548 88.4 3.6e-17
XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 545 87.9 4e-17
NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 545 88.0 4.8e-17
NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 543 87.6 5.1e-17
XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 543 87.7 6.5e-17
NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 483 79.2 1.5e-14
XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 483 79.4 1.9e-14
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 405 68.6 4.8e-11
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 405 68.6 4.9e-11
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 397 67.6 1.1e-10
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 397 67.6 1.1e-10
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 397 67.6 1.2e-10
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 397 67.6 1.2e-10
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 390 66.4 1.4e-10
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 386 66.0 2.9e-10
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 384 65.7 3.8e-10
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 384 65.7 3.8e-10
NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 383 65.6 3.9e-10
XP_011527411 (OMIM: 109535,606843) PREDICTED: tumo ( 166) 370 63.5 6.9e-10
NP_001309351 (OMIM: 109535,606843) tumor necrosis ( 225) 370 63.6 8.7e-10
XP_005260676 (OMIM: 109535,606843) PREDICTED: tumo ( 229) 370 63.6 8.8e-10
NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 342 59.8 1.6e-08
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 309 55.1 3.7e-07
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 295 53.1 1.1e-06
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 288 52.1 2e-06
XP_016866233 (OMIM: 605732) PREDICTED: tumor necro ( 444) 295 53.4 2e-06
NP_055267 (OMIM: 605732) tumor necrosis factor rec ( 655) 295 53.5 2.7e-06
XP_011540743 (OMIM: 153243) PREDICTED: tumor necro ( 594) 226 43.8 0.002
NP_001234 (OMIM: 153243) tumor necrosis factor rec ( 595) 226 43.8 0.002
NP_001034753 (OMIM: 603366) tumor necrosis factor ( 181) 214 41.8 0.0025
NP_003318 (OMIM: 600315,615593) tumor necrosis fac ( 277) 214 41.9 0.0035
XP_016857721 (OMIM: 600315,615593) PREDICTED: tumo ( 277) 214 41.9 0.0035
XP_016857720 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 214 42.0 0.0037
XP_011540377 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 214 42.0 0.0037
NP_683867 (OMIM: 603366) tumor necrosis factor rec ( 380) 214 42.0 0.0044
NP_683700 (OMIM: 603905) tumor necrosis factor rec ( 234) 210 41.3 0.0045
NP_004186 (OMIM: 603905) tumor necrosis factor rec ( 241) 210 41.3 0.0046
NP_003781 (OMIM: 603366) tumor necrosis factor rec ( 417) 214 42.1 0.0048
NP_683866 (OMIM: 603366) tumor necrosis factor rec ( 426) 214 42.1 0.0049
XP_016858211 (OMIM: 603905) PREDICTED: tumor necro ( 347) 210 41.4 0.0061
>>NP_003830 (OMIM: 174810,602080,603499,612301) tumor ne (616 aa)
initn: 4380 init1: 4380 opt: 4380 Z-score: 3305.8 bits: 621.8 E(85289): 2.1e-177
Smith-Waterman score: 4380; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616)
10 20 30 40 50 60
pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE
550 560 570 580 590 600
610
pF1KE0 PEKASRPVQEQGGAKA
::::::::::::::::
NP_003 PEKASRPVQEQGGAKA
610
>>XP_011524546 (OMIM: 174810,602080,603499,612301) PREDI (621 aa)
initn: 4366 init1: 3333 opt: 4360 Z-score: 3290.8 bits: 619.0 E(85289): 1.5e-176
Smith-Waterman score: 4360; 99.2% identity (99.2% similar) in 621 aa overlap (1-616:1-621)
10 20 30 40 50 60
pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 SQDCECCRRNTECAPGLGAQHP-----LQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNC
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_011 SQDCECCRRNTECAPGLGAQHPCTGWMLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 TFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 RKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 PEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE0 PTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 MSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 MGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFIS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE0 SGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGP
550 560 570 580 590 600
600 610
pF1KE0 EGLREPEKASRPVQEQGGAKA
:::::::::::::::::::::
XP_011 EGLREPEKASRPVQEQGGAKA
610 620
>>XP_016881554 (OMIM: 174810,602080,603499,612301) PREDI (566 aa)
initn: 3973 init1: 3333 opt: 3967 Z-score: 2995.8 bits: 564.3 E(85289): 4e-160
Smith-Waterman score: 3967; 99.1% identity (99.1% similar) in 566 aa overlap (56-616:1-566)
30 40 50 60 70 80
pF1KE0 VALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDK
::::::::::::::::::::::::::::::
XP_016 MSSKCTTTSDSVCLPCGPDEYLDSWNEEDK
10 20 30
90 100 110 120 130 140
pF1KE0 CLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHP---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPCTG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 --LQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 RKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGD
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 KESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQ
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE0 GEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEV
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE0 GENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSP
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE0 NWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGR
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE0 LPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGAA
460 470 480 490 500 510
570 580 590 600 610
pF1KE0 AAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQGGAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQGGAKA
520 530 540 550 560
>>XP_016881555 (OMIM: 174810,602080,603499,612301) PREDI (546 aa)
initn: 3321 init1: 3321 opt: 3321 Z-score: 2510.3 bits: 474.4 E(85289): 4.4e-133
Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 472 aa overlap (145-616:75-546)
120 130 140 150 160 170
pF1KE0 TAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTN
::::::::::::::::::::::::::::::
XP_016 TTGARTASAAAATPSARRAWAPSTRVRVGCLNKDTVCKPCLAGYFSDAFSSTDKCRPWTN
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE0 CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVC
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE0 YRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KE0 FPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPS
230 240 250 260 270 280
360 370 380 390 400 410
pF1KE0 QPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWT
290 300 310 320 330 340
420 430 440 450 460 470
pF1KE0 PMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAY
350 360 370 380 390 400
480 490 500 510 520 530
pF1KE0 GMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFI
410 420 430 440 450 460
540 550 560 570 580 590
pF1KE0 SSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGG
470 480 490 500 510 520
600 610
pF1KE0 PEGLREPEKASRPVQEQGGAKA
::::::::::::::::::::::
XP_016 PEGLREPEKASRPVQEQGGAKA
530 540
>>XP_016881553 (OMIM: 174810,602080,603499,612301) PREDI (580 aa)
initn: 3321 init1: 3321 opt: 3321 Z-score: 2509.9 bits: 474.4 E(85289): 4.6e-133
Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 472 aa overlap (145-616:109-580)
120 130 140 150 160 170
pF1KE0 TAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTN
::::::::::::::::::::::::::::::
XP_016 TTGARTASAAAATPSARRAWAPSTRVRVGCLNKDTVCKPCLAGYFSDAFSSTDKCRPWTN
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE0 CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVC
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE0 YRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKT
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE0 FPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPS
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 QPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWT
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE0 PMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAY
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE0 GMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFI
440 450 460 470 480 490
540 550 560 570 580 590
pF1KE0 SSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGG
500 510 520 530 540 550
600 610
pF1KE0 PEGLREPEKASRPVQEQGGAKA
::::::::::::::::::::::
XP_016 PEGLREPEKASRPVQEQGGAKA
560 570 580
>>XP_011524547 (OMIM: 174810,602080,603499,612301) PREDI (580 aa)
initn: 3321 init1: 3321 opt: 3321 Z-score: 2509.9 bits: 474.4 E(85289): 4.6e-133
Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 472 aa overlap (145-616:109-580)
120 130 140 150 160 170
pF1KE0 TAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTN
::::::::::::::::::::::::::::::
XP_011 TTGARTASAAAATPSARRAWAPSTRVRVGCLNKDTVCKPCLAGYFSDAFSSTDKCRPWTN
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE0 CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVC
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE0 YRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKT
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE0 FPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPS
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 QPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWT
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE0 PMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAY
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE0 GMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFI
440 450 460 470 480 490
540 550 560 570 580 590
pF1KE0 SSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGG
500 510 520 530 540 550
600 610
pF1KE0 PEGLREPEKASRPVQEQGGAKA
::::::::::::::::::::::
XP_011 PEGLREPEKASRPVQEQGGAKA
560 570 580
>>NP_001265197 (OMIM: 174810,602080,603499,612301) tumor (602 aa)
initn: 4258 init1: 3225 opt: 3241 Z-score: 2449.5 bits: 463.3 E(85289): 1.1e-129
Smith-Waterman score: 4237; 97.7% identity (97.7% similar) in 616 aa overlap (1-616:1-602)
10 20 30 40 50 60
pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
:::::::::::::::::::::: : :::::::::::::::::::::::
NP_001 SQDCECCRRNTECAPGLGAQHP-----------C---YFSDAFSSTDKCRPWTNCTFLGK
130 140 150 160
190 200 210 220 230 240
pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE0 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE0 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE0 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE0 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE
530 540 550 560 570 580
610
pF1KE0 PEKASRPVQEQGGAKA
::::::::::::::::
NP_001 PEKASRPVQEQGGAKA
590 600
>>NP_001257878 (OMIM: 174810,602080,603499,612301) tumor (263 aa)
initn: 1888 init1: 1888 opt: 1888 Z-score: 1437.2 bits: 274.8 E(85289): 2.6e-73
Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 262 aa overlap (1-262:1-262)
10 20 30 40 50 60
pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC
::::::::::::::::::::::
NP_001 ALTANLWHWINEACGRLSGDKEM
250 260
>>NP_001257879 (OMIM: 174810,602080,603499,612301) tumor (337 aa)
initn: 1750 init1: 1750 opt: 1763 Z-score: 1341.7 bits: 257.5 E(85289): 5.4e-68
Smith-Waterman score: 1804; 54.7% identity (54.7% similar) in 616 aa overlap (1-616:1-337)
10 20 30 40 50 60
pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMC
:::
NP_001 ALT---------------------------------------------------------
310 320 330 340 350 360
pF1KE0 YPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQL
NP_001 ------------------------------------------------------------
370 380 390 400 410 420
pF1KE0 LFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSEN
NP_001 ------------------------------------------------------------
430 440 450 460 470 480
pF1KE0 YLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPP
NP_001 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE0 EEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVM
::::::::::::::::::
NP_001 ------------------------------------------GNVTGNSNSTFISSGQVM
250 260
550 560 570 580 590 600
pF1KE0 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLRE
270 280 290 300 310 320
610
pF1KE0 PEKASRPVQEQGGAKA
::::::::::::::::
NP_001 PEKASRPVQEQGGAKA
330
>>NP_001257880 (OMIM: 174810,602080,603499,612301) tumor (299 aa)
initn: 1502 init1: 1502 opt: 1502 Z-score: 1146.2 bits: 221.2 E(85289): 4.2e-57
Smith-Waterman score: 1502; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KE0 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGK
:::::::::::::::::::::::::
NP_001 RVEHHGTEKSDAVCSSSLPARKPPNGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQE
190 200 210 220 230 240
>--
initn: 630 init1: 630 opt: 630 Z-score: 490.5 bits: 99.8 E(85289): 1.4e-20
Smith-Waterman score: 630; 100.0% identity (100.0% similar) in 94 aa overlap (523-616:206-299)
500 510 520 530 540 550
pF1KE0 PEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVS
::::::::::::::::::::::::::::::
NP_001 TFLGKRVEHHGTEKSDAVCSSSLPARKPPNGNVTGNSNSTFISSGQVMNFKGDIIVVYVS
180 190 200 210 220 230
560 570 580 590 600 610
pF1KE0 QTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTSQEGAAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQG
240 250 260 270 280 290
pF1KE0 GAKA
::::
NP_001 GAKA
616 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:59:09 2016 done: Fri Nov 4 03:59:11 2016
Total Scan time: 11.600 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]