FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0081, 1382 aa 1>>>pF1KE0081 1382 - 1382 aa - 1382 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4461+/-0.000503; mu= 22.9442+/- 0.031 mean_var=77.8909+/-15.864, 0's: 0 Z-trim(109.5): 278 B-trim: 936 in 1/48 Lambda= 0.145322 statistics sampled from 17332 (17640) to 17332 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.207), width: 16 Scan time: 13.410 The best scores are: opt bits E(85289) XP_016879286 (OMIM: 117800,607040) PREDICTED: ATP- (1382) 9025 1903.0 0 XP_016879285 (OMIM: 117800,607040) PREDICTED: ATP- (1382) 9025 1903.0 0 XP_016879287 (OMIM: 117800,607040) PREDICTED: ATP- (1382) 9025 1903.0 0 XP_016879289 (OMIM: 117800,607040) PREDICTED: ATP- (1382) 9025 1903.0 0 NP_115972 (OMIM: 117800,607040) ATP-binding casset (1382) 9025 1903.0 0 XP_016879284 (OMIM: 117800,607040) PREDICTED: ATP- (1382) 9025 1903.0 0 XP_016879288 (OMIM: 117800,607040) PREDICTED: ATP- (1382) 9025 1903.0 0 NP_149163 (OMIM: 117800,607040) ATP-binding casset (1382) 9025 1903.0 0 NP_660187 (OMIM: 117800,607040) ATP-binding casset (1344) 8253 1741.2 0 XP_016879291 (OMIM: 117800,607040) PREDICTED: ATP- (1063) 6893 1456.0 0 XP_011521699 (OMIM: 117800,607040) PREDICTED: ATP- (1063) 6893 1456.0 0 XP_016879290 (OMIM: 117800,607040) PREDICTED: ATP- (1346) 6080 1285.6 0 XP_016879292 (OMIM: 117800,607040) PREDICTED: ATP- ( 851) 5500 1163.9 0 XP_011521700 (OMIM: 117800,607040) PREDICTED: ATP- ( 759) 4929 1044.1 0 XP_016860981 (OMIM: 605251) PREDICTED: multidrug r (1259) 2660 568.6 1e-160 XP_011510616 (OMIM: 605251) PREDICTED: multidrug r (1437) 2660 568.6 1.2e-160 XP_005247116 (OMIM: 605251) PREDICTED: multidrug r (1437) 2660 568.6 1.2e-160 XP_005247115 (OMIM: 605251) PREDICTED: multidrug r (1437) 2660 568.6 1.2e-160 NP_005679 (OMIM: 605251) multidrug resistance-asso (1437) 2660 568.6 1.2e-160 NP_001306961 (OMIM: 605251) multidrug resistance-a ( 965) 2648 566.0 4.8e-160 XP_011510617 (OMIM: 605251) PREDICTED: multidrug r (1364) 2198 471.7 1.6e-131 XP_005254082 (OMIM: 605250) PREDICTED: multidrug r (1282) 2098 450.7 3.1e-125 XP_016875808 (OMIM: 605250) PREDICTED: multidrug r (1282) 2098 450.7 3.1e-125 NP_005836 (OMIM: 605250) multidrug resistance-asso (1325) 2098 450.7 3.2e-125 XP_016875810 (OMIM: 605250) PREDICTED: multidrug r ( 820) 1770 381.8 1.1e-104 XP_005253346 (OMIM: 239850,601439,608569,614050) P (1536) 1737 375.1 2.2e-102 XP_006719088 (OMIM: 239850,601439,608569,614050) P (1536) 1713 370.1 7.1e-101 NP_001162 (OMIM: 177850,264800,603234,614473) mult (1503) 1672 361.5 2.7e-98 XP_011520783 (OMIM: 177850,264800,603234,614473) P (1389) 1671 361.2 3e-98 XP_016878702 (OMIM: 177850,264800,603234,614473) P (1389) 1671 361.2 3e-98 XP_011520782 (OMIM: 177850,264800,603234,614473) P (1389) 1671 361.2 3e-98 XP_011520781 (OMIM: 177850,264800,603234,614473) P (1492) 1639 354.6 3.3e-96 XP_016873693 (OMIM: 125853,240800,256450,600509,60 ( 900) 1604 347.1 3.5e-94 XP_016873691 (OMIM: 125853,240800,256450,600509,60 (1103) 1604 347.1 4.2e-94 XP_016873689 (OMIM: 125853,240800,256450,600509,60 (1580) 1604 347.2 5.5e-94 XP_011518633 (OMIM: 125853,240800,256450,600509,60 (1581) 1604 347.2 5.5e-94 NP_000343 (OMIM: 125853,240800,256450,600509,60617 (1581) 1604 347.2 5.5e-94 NP_001274103 (OMIM: 125853,240800,256450,600509,60 (1582) 1604 347.2 5.5e-94 XP_016873688 (OMIM: 125853,240800,256450,600509,60 (1603) 1604 347.2 5.6e-94 XP_016873687 (OMIM: 125853,240800,256450,600509,60 (1603) 1604 347.2 5.6e-94 XP_016873686 (OMIM: 125853,240800,256450,600509,60 (1604) 1604 347.2 5.6e-94 XP_005257820 (OMIM: 604323) PREDICTED: canalicular (1463) 1502 325.8 1.4e-87 XP_011523726 (OMIM: 604323) PREDICTED: canalicular (1302) 1497 324.7 2.7e-87 NP_003777 (OMIM: 604323) canalicular multispecific (1527) 1497 324.8 3.1e-87 XP_006717693 (OMIM: 237500,601107) PREDICTED: cana (1313) 1478 320.8 4.3e-86 NP_000383 (OMIM: 237500,601107) canalicular multis (1545) 1478 320.8 4.9e-86 XP_016880754 (OMIM: 604323) PREDICTED: canalicular (1285) 1444 313.6 5.9e-84 XP_011523727 (OMIM: 604323) PREDICTED: canalicular (1285) 1444 313.6 5.9e-84 XP_011523724 (OMIM: 604323) PREDICTED: canalicular (1498) 1444 313.7 6.6e-84 XP_005253343 (OMIM: 239850,601439,608569,614050) P (1549) 1444 313.7 6.8e-84 >>XP_016879286 (OMIM: 117800,607040) PREDICTED: ATP-bind (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: XP_016 LR >>XP_016879285 (OMIM: 117800,607040) PREDICTED: ATP-bind (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: XP_016 LR >>XP_016879287 (OMIM: 117800,607040) PREDICTED: ATP-bind (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: XP_016 LR >>XP_016879289 (OMIM: 117800,607040) PREDICTED: ATP-bind (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: XP_016 LR >>NP_115972 (OMIM: 117800,607040) ATP-binding cassette s (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: NP_115 LR >>XP_016879284 (OMIM: 117800,607040) PREDICTED: ATP-bind (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: XP_016 LR >>XP_016879288 (OMIM: 117800,607040) PREDICTED: ATP-bind (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: XP_016 LR >>NP_149163 (OMIM: 117800,607040) ATP-binding cassette s (1382 aa) initn: 9025 init1: 9025 opt: 9025 Z-score: 10217.6 bits: 1903.0 E(85289): 0 Smith-Waterman score: 9025; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1330 1340 1350 1360 1370 1380 pF1KE0 LR :: NP_149 LR >>NP_660187 (OMIM: 117800,607040) ATP-binding cassette s (1344 aa) initn: 8253 init1: 8253 opt: 8253 Z-score: 9343.1 bits: 1741.2 E(85289): 0 Smith-Waterman score: 8693; 97.3% identity (97.3% similar) in 1382 aa overlap (1-1382:1-1344) 10 20 30 40 50 60 pF1KE0 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNPEAPGRAAVPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 WGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWLTPLMIQSLRSRLDENTIPPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SVHDASDKNVQRLHRLWEEEVSRRGIEKASVLLVMLRFQRTRLIFDALLGICFCIASVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 PILIIPKILEYSEEQLGNVVHGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 FAFEKLIQFKSVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIKLIKMYTWEKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 FAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLKLKLTASMAFSM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQDPSKALVFEEAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMML 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 GVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 QKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNGNAVPEHQLTQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 EEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 RESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIAVLLIVSVLSP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 YILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGLSSIHVYGKTED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 FISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGISSTPYSFKVMA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 VNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 IIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDALERTFLTKAI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 SKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDMETDTLIQRTI :::::::::::::::::::::: NP_660 --------------------------------------ILIDEATASIDMETDTLIQRTI 1270 1280 1330 1340 1350 1360 1370 1380 pF1KE0 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 REAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLFAALMATATSS 1290 1300 1310 1320 1330 1340 pF1KE0 LR :: NP_660 LR >>XP_016879291 (OMIM: 117800,607040) PREDICTED: ATP-bind (1063 aa) initn: 6893 init1: 6893 opt: 6893 Z-score: 7803.5 bits: 1456.0 E(85289): 0 Smith-Waterman score: 6893; 100.0% identity (100.0% similar) in 1063 aa overlap (320-1382:1-1063) 290 300 310 320 330 340 pF1KE0 ICSISSYFIIGYTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCI :::::::::::::::::::::::::::::: XP_016 MTRMAVKAQHHTSEVSDQRIRVTSEVLTCI 10 20 30 350 360 370 380 390 400 pF1KE0 KLIKMYTWEKPFAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLIKMYTWEKPFAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAVWVLIHTSLK 40 50 60 70 80 90 410 420 430 440 450 460 pF1KE0 LKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFFLQESPVFYVQTLQD 100 110 120 130 140 150 470 480 490 500 510 520 pF1KE0 PSKALVFEEATLSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSKALVFEEATLSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLGPELHK 160 170 180 190 200 210 530 540 550 560 570 580 pF1KE0 INLVVSKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INLVVSKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIR 220 230 240 250 260 270 590 600 610 620 630 640 pF1KE0 ENILMGGAYDKARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENILMGGAYDKARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVY 280 290 300 310 320 330 650 660 670 680 690 700 pF1KE0 SDRQIYLLDDPLSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDRQIYLLDDPLSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGK 340 350 360 370 380 390 710 720 730 740 750 760 pF1KE0 ICENGTHSELMQKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICENGTHSELMQKKGKYAQLIQKMHKEATSDMLQDTAKIAEKPKVESQALATSLEESLNG 400 410 420 430 440 450 770 780 790 800 810 820 pF1KE0 NAVPEHQLTQEEEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAVPEHQLTQEEEMEEGSLSWRVYHHYIQAAGGYMVSCIIFFFVVLIVFLTIFSFWWLSY 460 470 480 490 500 510 830 840 850 860 870 880 pF1KE0 WLEQGSGTNSSRESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WLEQGSGTNSSRESNGTMADLGNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTR 520 530 540 550 560 570 890 900 910 920 930 940 pF1KE0 KASTALHNKLFNKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KASTALHNKLFNKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVI 580 590 600 610 620 630 950 960 970 980 990 1000 pF1KE0 AVLLIVSVLSPYILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVLLIVSVLSPYILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFSHILNSLQGL 640 650 660 670 680 690 1010 1020 1030 1040 1050 1060 pF1KE0 SSIHVYGKTEDFISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSIHVYGKTEDFISQFKRLTDAQNNYLLLFLSSTRWMALRLEIMTNLVTLAVALFVAFGI 700 710 720 730 740 750 1070 1080 1090 1100 1110 1120 pF1KE0 SSTPYSFKVMAVNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTPYSFKVMAVNIVLQLASSFQATARIGLETEAQFTAVERILQYMKMCVSEAPLHMEGT 760 770 780 790 800 810 1130 1140 1150 1160 1170 1180 pF1KE0 SCPQGWPQHGEIIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCPQGWPQHGEIIFQDYHMKYRDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALF 820 830 840 850 860 870 1190 1200 1210 1220 1230 1240 pF1KE0 RLVEPMAGRILIDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLVEPMAGRILIDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWD 880 890 900 910 920 930 1250 1260 1270 1280 1290 1300 pF1KE0 ALERTFLTKAISKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALERTFLTKAISKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASID 940 950 960 970 980 990 1310 1320 1330 1340 1350 1360 pF1KE0 METDTLIQRTIREAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METDTLIQRTIREAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSL 1000 1010 1020 1030 1040 1050 1370 1380 pF1KE0 FAALMATATSSLR ::::::::::::: XP_016 FAALMATATSSLR 1060 1382 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:57:22 2016 done: Fri Nov 4 03:57:24 2016 Total Scan time: 13.410 Total Display time: 0.790 Function used was FASTA [36.3.4 Apr, 2011]