Result of FASTA (omim) for
pF1KE0086
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0086, 525 aa
1>>>pF1KE0086 525 - 525 aa - 525 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7867+/-0.000416; mu= 1.4822+/- 0.026
mean_var=344.2909+/-72.414, 0's: 0 Z-trim(121.6): 163 B-trim: 1315 in 1/59
Lambda= 0.069121
statistics sampled from 38274 (38460) to 38274 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.451), width: 16
Scan time: 11.160
The best scores are: opt bits E(85289)
NP_060267 (OMIM: 608531) BTB/POZ domain-containing ( 525) 3492 362.0 2.5e-99
XP_005259650 (OMIM: 608531) PREDICTED: BTB/POZ dom ( 377) 2496 262.5 1.6e-69
NP_079514 (OMIM: 608530) BTB/POZ domain-containing ( 482) 2496 262.7 1.8e-69
NP_001011885 (OMIM: 608530) BTB/POZ domain-contain ( 385) 1801 193.2 1.2e-48
XP_011526429 (OMIM: 608531) PREDICTED: BTB/POZ dom ( 204) 1391 152.1 1.5e-36
XP_016883217 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 461) 1303 143.7 1.2e-33
XP_016883218 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 461) 1303 143.7 1.2e-33
NP_001269479 (OMIM: 615566) BTB/POZ domain-contain ( 461) 1303 143.7 1.2e-33
NP_001269480 (OMIM: 615566) BTB/POZ domain-contain ( 461) 1303 143.7 1.2e-33
NP_055777 (OMIM: 615566) BTB/POZ domain-containing ( 522) 1303 143.7 1.3e-33
NP_852108 (OMIM: 615566) BTB/POZ domain-containing ( 565) 1303 143.8 1.3e-33
XP_016883219 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 371) 1079 121.2 5.3e-27
NP_001269481 (OMIM: 615566) BTB/POZ domain-contain ( 371) 1079 121.2 5.3e-27
NP_001269483 (OMIM: 615566) BTB/POZ domain-contain ( 371) 1079 121.2 5.3e-27
XP_016867930 (OMIM: 611119,612943,617055) PREDICTE ( 303) 381 51.5 4.2e-06
XP_016867929 (OMIM: 611119,612943,617055) PREDICTE ( 325) 381 51.6 4.4e-06
XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 381 51.8 6.3e-06
NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 381 51.8 6.5e-06
NP_061334 (OMIM: 611119,612943,617055) kelch-like ( 538) 363 50.0 2.1e-05
XP_016865716 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 353 48.9 3.4e-05
XP_011512584 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 353 48.9 3.4e-05
XP_011512583 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 391) 353 48.9 3.4e-05
XP_011512582 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 401) 353 48.9 3.5e-05
XP_011512581 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 612) 353 49.1 4.6e-05
NP_443125 (OMIM: 611237) BTB/POZ domain-containing ( 612) 353 49.1 4.6e-05
NP_001092742 (OMIM: 611237) BTB/POZ domain-contain ( 612) 353 49.1 4.6e-05
NP_006054 (OMIM: 607701,615731) kelch-like protein ( 606) 290 42.8 0.0036
XP_006715820 (OMIM: 611119,612943,617055) PREDICTE ( 338) 277 41.2 0.0059
XP_006715817 (OMIM: 611119,612943,617055) PREDICTE ( 577) 277 41.5 0.0085
XP_006715818 (OMIM: 611119,612943,617055) PREDICTE ( 577) 277 41.5 0.0085
XP_006715816 (OMIM: 611119,612943,617055) PREDICTE ( 599) 277 41.5 0.0088
>>NP_060267 (OMIM: 608531) BTB/POZ domain-containing pro (525 aa)
initn: 3492 init1: 3492 opt: 3492 Z-score: 1904.3 bits: 362.0 E(85289): 2.5e-99
Smith-Waterman score: 3492; 100.0% identity (100.0% similar) in 525 aa overlap (1-525:1-525)
10 20 30 40 50 60
pF1KE0 MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 APPGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 APPGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 CLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 VTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 DRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 NIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGT
430 440 450 460 470 480
490 500 510 520
pF1KE0 KGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
:::::::::::::::::::::::::::::::::::::::::::::
NP_060 KGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
490 500 510 520
>>XP_005259650 (OMIM: 608531) PREDICTED: BTB/POZ domain- (377 aa)
initn: 2496 init1: 2496 opt: 2496 Z-score: 1369.3 bits: 262.5 E(85289): 1.6e-69
Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 377 aa overlap (149-525:1-377)
120 130 140 150 160 170
pF1KE0 VHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFL
::::::::::::::::::::::::::::::
XP_005 MFNGGMATTSTEIELPDVEPAAFLALLKFL
10 20 30
180 190 200 210 220 230
pF1KE0 YSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLA
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE0 SLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQ
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE0 LQVTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQVTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVE
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE0 FIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDY
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE0 QVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHY
280 290 300 310 320 330
480 490 500 510 520
pF1KE0 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
340 350 360 370
>>NP_079514 (OMIM: 608530) BTB/POZ domain-containing pro (482 aa)
initn: 2397 init1: 2156 opt: 2496 Z-score: 1368.0 bits: 262.7 E(85289): 1.8e-69
Smith-Waterman score: 2496; 77.6% identity (89.0% similar) in 491 aa overlap (42-525:7-482)
20 30 40 50 60 70
pF1KE0 CPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPT-PPAPPGPGTDAQ
:::. :..: : :::. :: ::.:..
NP_079 MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSS---
10 20 30
80 90 100 110 120
pF1KE0 AAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSS-
:: :::: :::::.: ...::::::::.:.: ::.:..::: ..
NP_079 ----------LGP-LLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAA
40 50 60 70 80
130 140 150 160 170 180
pF1KE0 -----QRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQ
:::::::::::.:::::::::::::::::.::::::::::::::::.::::::::
NP_079 AAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQ
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE0 IGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLEN
::::::::::::::::::::::::::::: :.::::::::::::::::::::::::::..
NP_079 IGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDT
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 IDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPE
:::.: :::.::::::::.::: ::::::::.::: :::.:::::.::::::::: ::
NP_079 IDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE0 NRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPR
:..:::::::.:::::::::::::::::::::: :::::.::::::::::::::.:::::
NP_079 NKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPR
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE0 CCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQI
:::::::: ::::::::::::::::::::::.::.:: .:::::::::::::::::::::
NP_079 CCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISIVGFGLYGSIHGPTDYQVNIQI
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE0 IHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLR
:. ... .::::::::::::.:.:::::::::.:.:::: :::::::::::::::::::.
NP_079 IEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLK
390 400 410 420 430 440
490 500 510 520
pF1KE0 KVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
::.::.:.. .:: : : . :::::::.:::::::.::::
NP_079 KVVHETPAA-SKTVFFFFSSPGNNNGTSIEDGQIPEIIFYT
450 460 470 480
>>NP_001011885 (OMIM: 608530) BTB/POZ domain-containing (385 aa)
initn: 1816 init1: 1575 opt: 1801 Z-score: 994.6 bits: 193.2 E(85289): 1.2e-48
Smith-Waterman score: 1801; 77.6% identity (87.4% similar) in 366 aa overlap (42-400:7-357)
20 30 40 50 60 70
pF1KE0 CPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPT-PPAPPGPGTDAQ
:::. :..: : :::. :: ::.:..
NP_001 MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSS---
10 20 30
80 90 100 110 120
pF1KE0 AAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSS-
:: :::: :::::.: ...::::::::.:.: ::.:..::: ..
NP_001 ----------LGP-LLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAA
40 50 60 70 80
130 140 150 160 170 180
pF1KE0 -----QRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQ
:::::::::::.:::::::::::::::::.::::::::::::::::.::::::::
NP_001 AAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQ
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE0 IGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLEN
::::::::::::::::::::::::::::: :.::::::::::::::::::::::::::..
NP_001 IGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDT
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 IDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPE
:::.: :::.::::::::.::: ::::::::.::: :::.:::::.::::::::: ::
NP_001 IDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFG
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE0 NRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPR
:..:::::::.:::::::::::::::::::::: :::::.::::::::::::::.:::::
NP_001 NKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPR
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE0 CCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQI
:::::::: ::::::::::::::::::::: :.: :
NP_001 CCLRGKECCINRFQQVESRWGYSGTSDRIR-SLNMRKSKPWDRMIPALVVMGQLTHSGSC
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE0 IHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPDSHYGTKGLR
NP_001 SRNP
>>XP_011526429 (OMIM: 608531) PREDICTED: BTB/POZ domain- (204 aa)
initn: 1391 init1: 1391 opt: 1391 Z-score: 777.0 bits: 152.1 E(85289): 1.5e-36
Smith-Waterman score: 1391; 100.0% identity (100.0% similar) in 204 aa overlap (322-525:1-204)
300 310 320 330 340 350
pF1KE0 AECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTV
::::::::::::::::::::::::::::::
XP_011 MTIEEFAAGPAQSGILVDREVVSLFLHFTV
10 20 30
360 370 380 390 400 410
pF1KE0 NPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKPRVEFIDRPRCCLRGKECSINRFQQVESRWGYSGTSDRIRFSVNKRIFVVGFGLYGS
40 50 60 70 80 90
420 430 440 450 460 470
pF1KE0 IHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATL
100 110 120 130 140 150
480 490 500 510 520
pF1KE0 KGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGPDSHYGTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
160 170 180 190 200
>>XP_016883217 (OMIM: 615566) PREDICTED: BTB/POZ domain- (461 aa)
initn: 1266 init1: 957 opt: 1303 Z-score: 725.3 bits: 143.7 E(85289): 1.2e-33
Smith-Waterman score: 1303; 46.6% identity (75.9% similar) in 436 aa overlap (93-524:35-460)
70 80 90 100 110 120
pF1KE0 PGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFL
: :::. ::..:: :..:::... ::::.
XP_016 IFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFV
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE0 VGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDE
:: ..::.:.:..::::::.:: ::: : .: . ::..::::::::::.::..: ::
XP_016 VGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDE
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE0 VQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCL
.... .::..:::.:::: :: : ::.::. .: : :: .::.:. ::.::.:.. :
XP_016 IDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCW
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE0 ENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVT
: :: .. :. .::: :::..:: ..:.:.::. .:. .:.:.. :.:.:::::.: ..
XP_016 EVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE0 PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDR
::.:::::::: :::.: :....:: : ::::.:. :. ..:: .:. ::...:...
XP_016 IENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSK
250 260 270 280 290 300
370 380 390 400 410
pF1KE0 PRCCLRGKECSINRFQQVESR---WGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQ
: : ..: .:::. : : : : : :.:.:.::.:..::::::: : ..:.
XP_016 ARKGLVPQRC--HRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYS
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE0 VNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHY
..:.. . ...::::: . . :::..:: : :. ::.. :.. ::: . : : . :..
XP_016 AKIELKR--QGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
370 380 390 400 410 420
480 490 500 510 520
pF1KE0 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
: .:. .: .:. : .. ..:::.:. :::::.:::
XP_016 GQEGMTEVQC------GKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
430 440 450 460
>>XP_016883218 (OMIM: 615566) PREDICTED: BTB/POZ domain- (461 aa)
initn: 1266 init1: 957 opt: 1303 Z-score: 725.3 bits: 143.7 E(85289): 1.2e-33
Smith-Waterman score: 1303; 46.6% identity (75.9% similar) in 436 aa overlap (93-524:35-460)
70 80 90 100 110 120
pF1KE0 PGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFL
: :::. ::..:: :..:::... ::::.
XP_016 IFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFV
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE0 VGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDE
:: ..::.:.:..::::::.:: ::: : .: . ::..::::::::::.::..: ::
XP_016 VGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDE
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE0 VQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCL
.... .::..:::.:::: :: : ::.::. .: : :: .::.:. ::.::.:.. :
XP_016 IDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCW
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE0 ENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVT
: :: .. :. .::: :::..:: ..:.:.::. .:. .:.:.. :.:.:::::.: ..
XP_016 EVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE0 PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDR
::.:::::::: :::.: :....:: : ::::.:. :. ..:: .:. ::...:...
XP_016 IENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSK
250 260 270 280 290 300
370 380 390 400 410
pF1KE0 PRCCLRGKECSINRFQQVESR---WGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQ
: : ..: .:::. : : : : : :.:.:.::.:..::::::: : ..:.
XP_016 ARKGLVPQRC--HRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYS
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE0 VNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHY
..:.. . ...::::: . . :::..:: : :. ::.. :.. ::: . : : . :..
XP_016 AKIELKR--QGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
370 380 390 400 410 420
480 490 500 510 520
pF1KE0 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
: .:. .: .:. : .. ..:::.:. :::::.:::
XP_016 GQEGMTEVQC------GKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
430 440 450 460
>>NP_001269479 (OMIM: 615566) BTB/POZ domain-containing (461 aa)
initn: 1266 init1: 957 opt: 1303 Z-score: 725.3 bits: 143.7 E(85289): 1.2e-33
Smith-Waterman score: 1303; 46.6% identity (75.9% similar) in 436 aa overlap (93-524:35-460)
70 80 90 100 110 120
pF1KE0 PGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFL
: :::. ::..:: :..:::... ::::.
NP_001 IFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFV
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE0 VGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDE
:: ..::.:.:..::::::.:: ::: : .: . ::..::::::::::.::..: ::
NP_001 VGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDE
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE0 VQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCL
.... .::..:::.:::: :: : ::.::. .: : :: .::.:. ::.::.:.. :
NP_001 IDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCW
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE0 ENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVT
: :: .. :. .::: :::..:: ..:.:.::. .:. .:.:.. :.:.:::::.: ..
NP_001 EVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE0 PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDR
::.:::::::: :::.: :....:: : ::::.:. :. ..:: .:. ::...:...
NP_001 IENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSK
250 260 270 280 290 300
370 380 390 400 410
pF1KE0 PRCCLRGKECSINRFQQVESR---WGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQ
: : ..: .:::. : : : : : :.:.:.::.:..::::::: : ..:.
NP_001 ARKGLVPQRC--HRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYS
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE0 VNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHY
..:.. . ...::::: . . :::..:: : :. ::.. :.. ::: . : : . :..
NP_001 AKIELKR--QGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
370 380 390 400 410 420
480 490 500 510 520
pF1KE0 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
: .:. .: .:. : .. ..:::.:. :::::.:::
NP_001 GQEGMTEVQC------GKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
430 440 450 460
>>NP_001269480 (OMIM: 615566) BTB/POZ domain-containing (461 aa)
initn: 1266 init1: 957 opt: 1303 Z-score: 725.3 bits: 143.7 E(85289): 1.2e-33
Smith-Waterman score: 1303; 46.6% identity (75.9% similar) in 436 aa overlap (93-524:35-460)
70 80 90 100 110 120
pF1KE0 PGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFL
: :::. ::..:: :..:::... ::::.
NP_001 IFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFV
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE0 VGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDE
:: ..::.:.:..::::::.:: ::: : .: . ::..::::::::::.::..: ::
NP_001 VGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDE
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE0 VQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCL
.... .::..:::.:::: :: : ::.::. .: : :: .::.:. ::.::.:.. :
NP_001 IDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCW
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE0 ENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVT
: :: .. :. .::: :::..:: ..:.:.::. .:. .:.:.. :.:.:::::.: ..
NP_001 EVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALS
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE0 PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDR
::.:::::::: :::.: :....:: : ::::.:. :. ..:: .:. ::...:...
NP_001 IENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSK
250 260 270 280 290 300
370 380 390 400 410
pF1KE0 PRCCLRGKECSINRFQQVESR---WGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQ
: : ..: .:::. : : : : : :.:.:.::.:..::::::: : ..:.
NP_001 ARKGLVPQRC--HRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYS
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE0 VNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHY
..:.. . ...::::: . . :::..:: : :. ::.. :.. ::: . : : . :..
NP_001 AKIELKR--QGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
370 380 390 400 410 420
480 490 500 510 520
pF1KE0 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
: .:. .: .:. : .. ..:::.:. :::::.:::
NP_001 GQEGMTEVQC------GKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
430 440 450 460
>>NP_055777 (OMIM: 615566) BTB/POZ domain-containing pro (522 aa)
initn: 1266 init1: 957 opt: 1303 Z-score: 724.6 bits: 143.7 E(85289): 1.3e-33
Smith-Waterman score: 1303; 46.6% identity (75.9% similar) in 436 aa overlap (93-524:96-521)
70 80 90 100 110 120
pF1KE0 PGPGTDAQAAGAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFL
: :::. ::..:: :..:::... ::::.
NP_055 IFPRKKPANSSSTSVQQYHQQNLSNNNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDE
:: ..::.:.:..::::::.:: ::: : .: . ::..::::::::::.::..: ::
NP_055 VGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCL
.... .::..:::.:::: :: : ::.::. .: : :: .::.:. ::.::.:.. :
NP_055 IDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVT
: :: .. :. .::: :::..:: ..:.:.::. .:. .:.:.. :.:.:::::.: ..
NP_055 EVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALNWAEVECQRQDLALS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PENRRKVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDR
::.:::::::: :::.: :....:: : ::::.:. :. ..:: .:. ::...:...
NP_055 IENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSK
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 PRCCLRGKECSINRFQQVESR---WGYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQ
: : ..: .:::. : : : : : :.:.:.::.:..::::::: : ..:.
NP_055 ARKGLVPQRC--HRFQSCAYRSNQWRYRGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 VNIQIIHTDSNTVLGQNDTGFSCDGSASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHY
..:.. . ...::::: . . :::..:: : :. ::.. :.. ::: . : : . :..
NP_055 AKIELKR--QGVVLGQNLSKYFSDGSSNTFPVWFEYPVQIEPDTFYTASVILDGNELSYF
430 440 450 460 470 480
480 490 500 510 520
pF1KE0 GTKGLRKVTHESPTTGAKTCFTFCYAAGNNNGTSVEDGQIPEVIFYT
: .:. .: .:. : .. ..:::.:. :::::.:::
NP_055 GQEGMTEVQC------GKVTVQFQCSSDSTNGTGVQGGQIPELIFYA
490 500 510 520
525 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:43:35 2016 done: Fri Nov 4 03:43:36 2016
Total Scan time: 11.160 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]