Result of FASTA (omim) for pF1KE0091
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0091, 632 aa
  1>>>pF1KE0091 632 - 632 aa - 632 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1015+/-0.000399; mu= 20.6167+/- 0.025
 mean_var=69.7799+/-14.430, 0's: 0 Z-trim(111.4): 97  B-trim: 1102 in 1/49
 Lambda= 0.153536
 statistics sampled from 19865 (19965) to 19865 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.571), E-opt: 0.2 (0.234), width:  16
 Scan time:  7.500

The best scores are:                                      opt bits E(85289)
NP_055044 (OMIM: 607952) sodium- and chloride-depe ( 632) 4383 980.5       0
NP_057699 (OMIM: 615097) sodium- and chloride-depe ( 602) 2961 665.5 1.5e-190
XP_016862562 (OMIM: 607952) PREDICTED: sodium- and ( 458) 2933 659.3 8.6e-189
NP_001193860 (OMIM: 603080) sodium- and chloride-d ( 614) 2831 636.8 6.9e-182
NP_001116320 (OMIM: 603080) sodium- and chloride-d ( 614) 2831 636.8 6.9e-182
XP_011519312 (OMIM: 603080) PREDICTED: sodium- and ( 614) 2831 636.8 6.9e-182
NP_001116319 (OMIM: 603080) sodium- and chloride-d ( 614) 2831 636.8 6.9e-182
NP_003035 (OMIM: 603080) sodium- and chloride-depe ( 614) 2831 636.8 6.9e-182
XP_005253804 (OMIM: 603080) PREDICTED: sodium- and ( 610) 2808 631.7 2.3e-180
XP_005253805 (OMIM: 603080) PREDICTED: sodium- and ( 571) 2799 629.6 8.9e-180
XP_006719068 (OMIM: 603080) PREDICTED: sodium- and ( 570) 2793 628.3 2.2e-179
XP_011532332 (OMIM: 186854) PREDICTED: sodium- and ( 620) 2619 589.8 9.5e-168
NP_003034 (OMIM: 186854) sodium- and chloride-depe ( 620) 2619 589.8 9.5e-168
XP_006713370 (OMIM: 186854) PREDICTED: sodium- and ( 649) 2619 589.8 9.8e-168
NP_001127839 (OMIM: 186854) sodium- and chloride-d ( 721) 2619 589.8 1.1e-167
XP_011532335 (OMIM: 607952) PREDICTED: sodium- and ( 381) 2599 585.2 1.4e-166
XP_011519314 (OMIM: 615097) PREDICTED: sodium- and ( 483) 2376 535.9 1.2e-151
NP_005620 (OMIM: 300036,300352) sodium- and chlori ( 635) 2329 525.6 2.1e-148
NP_001177926 (OMIM: 615097) sodium- and chloride-d ( 510) 2195 495.8 1.5e-139
XP_011519315 (OMIM: 615097) PREDICTED: sodium- and ( 440) 2164 488.9 1.6e-137
XP_011519316 (OMIM: 615097) PREDICTED: sodium- and ( 440) 2164 488.9 1.6e-137
NP_003033 (OMIM: 137165,616421) sodium- and chlori ( 599) 2158 487.7 5.1e-137
XP_016862561 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_011532327 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_016862560 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_005265467 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_006713369 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_011532329 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_005265468 (OMIM: 137165,616421) PREDICTED: sodi ( 599) 2158 487.7 5.1e-137
XP_016875333 (OMIM: 615097) PREDICTED: sodium- and ( 394) 2075 469.2 1.3e-131
XP_016875330 (OMIM: 603080) PREDICTED: sodium- and ( 426) 2035 460.3 6.2e-129
NP_001136278 (OMIM: 300036,300352) sodium- and chl ( 520) 2004 453.5 8.4e-127
XP_011532333 (OMIM: 186854) PREDICTED: sodium- and ( 449) 1917 434.2 4.8e-121
NP_055043 (OMIM: 606205) sodium-dependent proline  ( 636) 1772 402.2 2.9e-111
NP_001165972 (OMIM: 163970,604715) sodium-dependen ( 617) 1765 400.6 8.3e-111
NP_001034 (OMIM: 163970,604715) sodium-dependent n ( 617) 1765 400.6 8.3e-111
XP_006721326 (OMIM: 163970,604715) PREDICTED: sodi ( 628) 1765 400.6 8.4e-111
XP_011521597 (OMIM: 163970,604715) PREDICTED: sodi ( 628) 1765 400.6 8.4e-111
NP_001165975 (OMIM: 163970,604715) sodium-dependen ( 628) 1765 400.6 8.4e-111
XP_016875334 (OMIM: 615097) PREDICTED: sodium- and ( 359) 1746 396.3  1e-109
XP_006719071 (OMIM: 615097) PREDICTED: sodium- and ( 359) 1746 396.3  1e-109
NP_001036 (OMIM: 164230,182138,607834) sodium-depe ( 630) 1733 393.5 1.2e-108
NP_001035 (OMIM: 126455,188890,613135) sodium-depe ( 620) 1686 383.1 1.5e-105
XP_016875335 (OMIM: 615097) PREDICTED: sodium- and ( 325) 1634 371.4 2.7e-102
XP_016875336 (OMIM: 615097) PREDICTED: sodium- and ( 325) 1634 371.4 2.7e-102
NP_001136277 (OMIM: 300036,300352) sodium- and chl ( 625) 1607 365.6 2.9e-100
XP_016865259 (OMIM: 606205) PREDICTED: sodium-depe ( 555) 1547 352.3 2.6e-96
NP_001304335 (OMIM: 607952) sodium- and chloride-d ( 208) 1467 334.3 2.6e-91
XP_016875332 (OMIM: 615097) PREDICTED: sodium- and ( 442) 1408 321.4 4.1e-87
NP_001165973 (OMIM: 163970,604715) sodium-dependen ( 512) 1388 317.1 9.9e-86


>>NP_055044 (OMIM: 607952) sodium- and chloride-dependen  (632 aa)
 initn: 4383 init1: 4383 opt: 4383  Z-score: 5244.2  bits: 980.5 E(85289):    0
Smith-Waterman score: 4383; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KE0 MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGIT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 CWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 VEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 DAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 YEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 AVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 IFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 NNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKL
              550       560       570       580       590       600

              610       620       630  
pF1KE0 GVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
       ::::::::::::::::::::::::::::::::
NP_055 GVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
              610       620       630  

>>NP_057699 (OMIM: 615097) sodium- and chloride-dependen  (602 aa)
 initn: 2976 init1: 2148 opt: 2961  Z-score: 3542.2  bits: 665.5 E(85289): 1.5e-190
Smith-Waterman score: 2961; 70.8% identity (88.8% similar) in 579 aa overlap (27-603:7-583)

               10        20        30        40          50        
pF1KE0 MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRV--KRDKAVHERGHWNNKVE
                                 : .:.: .   .: .  :.. .. ::::::::.:
NP_057                     MDSRVSGTTSNGETKPVYPVMEKKEEDGTLERGHWNNKME
                                   10        20        30        40

       60        70        80        90       100       110        
pF1KE0 FVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGG
       ::::::::::::::::::::::::::::::.:::.::.. ::::::.:::::::.::.::
NP_057 FVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGG
               50        60        70        80        90       100

      120       130       140       150       160       170        
pF1KE0 ITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTE
       .: :::.::.:::::::.:.:   :::::::.::::.::: . :: .:::. : ::::::
NP_057 VTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTE
              110       120       130       140       150       160

      180       190       200       210       220       230        
pF1KE0 NCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTI
       .:.:::: : .. . .: .::::::.::::.::: :::::.:.: :::::::::: ::.:
NP_057 HCMEFQKTN-GSLNGTS-ENATSPVIEFWERRVLKISDGIQHLGALRWELALCLLLAWVI
               170        180       190       200       210        

      240       250       260       270       280       290        
pF1KE0 CYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQV
       ::::::::.:::::::: ::::::.::..:::::::::::..::.:::::.:.:: ::::
NP_057 CYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQV
      220       230       240       250       260       270        

      300       310       320       330       340       350        
pF1KE0 WVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGF
       :.:::::::::.::::::::::::::.:.:::::::: :: :::::::::::::::.:::
NP_057 WMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGF
      280       290       300       310       320       330        

      360       370       380       390       400       410        
pF1KE0 MAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESL
       :. ::::::.:::::::::::::::.::.:.:.:::::  ::.:...:::::::::::::
NP_057 MSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESL
      340       350       360       370       380       390        

      420       430       440       450       460       470        
pF1KE0 VTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLF
       :::.:::::.:::.  :::.:::..::.:...::.::::::::.::::: ::::::::::
NP_057 VTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLF
      400       410       420       430       440       450        

      480       490       500       510       520       530        
pF1KE0 VAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPL
       ::::: .:..::::..::::::::::::::  :::.::...::..:.. :.: :::: ::
NP_057 VAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPL
      460       470       480       490       500       510        

      540       550       560       570       580       590        
pF1KE0 KYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRG
        ::. :::: :: ..:::.:::::.::: :    .   .: . :....:  :. :: .:.
NP_057 TYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQRN
      520       530       540       550       560       570        

      600       610       620       630  
pF1KE0 KLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
         : :                             
NP_057 PAGPSAPATPRTSLLRLTELESHC          
      580       590       600            

>>XP_016862562 (OMIM: 607952) PREDICTED: sodium- and chl  (458 aa)
 initn: 2916 init1: 2916 opt: 2933  Z-score: 3510.4  bits: 659.3 E(85289): 8.6e-189
Smith-Waterman score: 2933; 98.4% identity (98.9% similar) in 435 aa overlap (198-632:25-458)

       170       180       190       200       210       220       
pF1KE0 WATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWE
                                     .:.::    : :::::::::::::::::::
XP_016       MCLCRMPPPLSWSFGNEEAETQRGDAASPRWSSW-HRVLAISDGIEHIGNLRWE
                     10        20        30         40        50   

       230       240       250       260       270       280       
pF1KE0 LALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLY
            60        70        80        90       100       110   

       290       300       310       320       330       340       
pF1KE0 PDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFV
           120       130       140       150       160       170   

       350       360       370       380       390       400       
pF1KE0 AGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLG
           180       190       200       210       220       230   

       410       420       430       440       450       460       
pF1KE0 LDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFD
           240       250       260       270       280       290   

       470       480       490       500       510       520       
pF1KE0 SYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGI
           300       310       320       330       340       350   

       530       540       550       560       570       580       
pF1KE0 FIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKL
           360       370       380       390       400       410   

       590       600       610       620       630  
pF1KE0 TTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
           420       430       440       450        

>>NP_001193860 (OMIM: 603080) sodium- and chloride-depen  (614 aa)
 initn: 2843 init1: 2057 opt: 2831  Z-score: 3386.5  bits: 636.8 E(85289): 6.9e-182
Smith-Waterman score: 2831; 67.8% identity (87.7% similar) in 587 aa overlap (47-632:33-614)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
NP_001 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
NP_001 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
NP_001 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
NP_001 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
NP_001 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
NP_001 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
NP_001 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
NP_001 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
NP_001 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590       600       610     
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAK
       ..:::::.:.::.. ::. ::.: . ..:..: ::...: .  .       .  :   . 
NP_001 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
              550       560       570       580       590       600

         620       630  
pF1KE0 LKSDGTIAAITEKETHF
        . .: ::.  :::::.
NP_001 TR-EGLIAG--EKETHL
                 610    

>>NP_001116320 (OMIM: 603080) sodium- and chloride-depen  (614 aa)
 initn: 2843 init1: 2057 opt: 2831  Z-score: 3386.5  bits: 636.8 E(85289): 6.9e-182
Smith-Waterman score: 2831; 67.8% identity (87.7% similar) in 587 aa overlap (47-632:33-614)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
NP_001 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
NP_001 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
NP_001 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
NP_001 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
NP_001 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
NP_001 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
NP_001 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
NP_001 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
NP_001 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590       600       610     
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAK
       ..:::::.:.::.. ::. ::.: . ..:..: ::...: .  .       .  :   . 
NP_001 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
              550       560       570       580       590       600

         620       630  
pF1KE0 LKSDGTIAAITEKETHF
        . .: ::.  :::::.
NP_001 TR-EGLIAG--EKETHL
                 610    

>>XP_011519312 (OMIM: 603080) PREDICTED: sodium- and chl  (614 aa)
 initn: 2843 init1: 2057 opt: 2831  Z-score: 3386.5  bits: 636.8 E(85289): 6.9e-182
Smith-Waterman score: 2831; 67.8% identity (87.7% similar) in 587 aa overlap (47-632:33-614)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
XP_011 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
XP_011 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
XP_011 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
XP_011 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
XP_011 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
XP_011 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
XP_011 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
XP_011 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
XP_011 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590       600       610     
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAK
       ..:::::.:.::.. ::. ::.: . ..:..: ::...: .  .       .  :   . 
XP_011 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
              550       560       570       580       590       600

         620       630  
pF1KE0 LKSDGTIAAITEKETHF
        . .: ::.  :::::.
XP_011 TR-EGLIAG--EKETHL
                 610    

>>NP_001116319 (OMIM: 603080) sodium- and chloride-depen  (614 aa)
 initn: 2843 init1: 2057 opt: 2831  Z-score: 3386.5  bits: 636.8 E(85289): 6.9e-182
Smith-Waterman score: 2831; 67.8% identity (87.7% similar) in 587 aa overlap (47-632:33-614)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
NP_001 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
NP_001 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
NP_001 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
NP_001 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
NP_001 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
NP_001 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
NP_001 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
NP_001 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
NP_001 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590       600       610     
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAK
       ..:::::.:.::.. ::. ::.: . ..:..: ::...: .  .       .  :   . 
NP_001 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
              550       560       570       580       590       600

         620       630  
pF1KE0 LKSDGTIAAITEKETHF
        . .: ::.  :::::.
NP_001 TR-EGLIAG--EKETHL
                 610    

>>NP_003035 (OMIM: 603080) sodium- and chloride-dependen  (614 aa)
 initn: 2843 init1: 2057 opt: 2831  Z-score: 3386.5  bits: 636.8 E(85289): 6.9e-182
Smith-Waterman score: 2831; 67.8% identity (87.7% similar) in 587 aa overlap (47-632:33-614)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
NP_003 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
NP_003 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
NP_003 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
NP_003 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
NP_003 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
NP_003 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
NP_003 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
NP_003 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
NP_003 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590       600       610     
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAK
       ..:::::.:.::.. ::. ::.: . ..:..: ::...: .  .       .  :   . 
NP_003 FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
              550       560       570       580       590       600

         620       630  
pF1KE0 LKSDGTIAAITEKETHF
        . .: ::.  :::::.
NP_003 TR-EGLIAG--EKETHL
                 610    

>>XP_005253804 (OMIM: 603080) PREDICTED: sodium- and chl  (610 aa)
 initn: 2808 init1: 2022 opt: 2808  Z-score: 3359.0  bits: 631.7 E(85289): 2.3e-180
Smith-Waterman score: 2808; 69.5% identity (89.1% similar) in 561 aa overlap (47-604:33-589)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
XP_005 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
XP_005 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
XP_005 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
XP_005 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
XP_005 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
XP_005 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
XP_005 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
XP_005 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
XP_005 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590         600       610   
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTP--STDLKMRGKLGVSPRMVTVNDCD
       ..:::::.:.::.. ::. ::.:  : . . .: :  .. .: : .  ..:         
XP_005 FLALSSMVCVPLFVVITLLKTRG--PFRKMAVTIPVITSAFKARRREQMAPPPPPPTVVA
              550       560         570       580       590        

           620       630  
pF1KE0 AKLKSDGTIAAITEKETHF
                          
XP_005 VPLIRRKIIDTY       
      600       610       

>>XP_005253805 (OMIM: 603080) PREDICTED: sodium- and chl  (571 aa)
 initn: 2814 init1: 2028 opt: 2799  Z-score: 3348.6  bits: 629.6 E(85289): 8.9e-180
Smith-Waterman score: 2799; 71.3% identity (90.7% similar) in 540 aa overlap (47-585:33-570)

         20        30        40        50        60        70      
pF1KE0 EARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRF
                                     :..::.:.::.:::::::::::::::::::
XP_005 GKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRF
             10        20        30        40        50        60  

         80        90       100       110       120       130      
pF1KE0 PYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYAT
       ::::::::::::.::: .::. :::::::::.::::.::.:..: :::.::::.::: :.
XP_005 PYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLAS
             70        80        90       100       110       120  

        140       150       160       170       180       190      
pF1KE0 QVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVS-
        :::..::::::::::::.::: . ::.::::.::.. ::::.:..:  :: :. . :. 
XP_005 VVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF--LNHSGAGTVTP
            130       140       150       160         170       180

         200       210       220       230       240       250     
pF1KE0 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY
       ..: :::::::::.:::.:..::. .:.:::::::::: ::.:::::::::.::::::::
XP_005 FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
              190       200       210       220       230       240

         260       270       280       290       300       310     
pF1KE0 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG
        ::::::.::.:::::::::::: .:: .:: ::: ::.:::::.:::::::::.::: :
XP_005 FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
              250       260       270       280       290       300

         320       330       340       350       360       370     
pF1KE0 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP
       :::::::::.:.::::.::: :: :::.:::::::..::.::::. ::::::.:::::::
XP_005 CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
              310       320       330       340       350       360

         380       390       400       410       420       430     
pF1KE0 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR
       ::::::.:::::::::: ::. :::.::::::::::::::: :::: .::.:. .:.. :
XP_005 GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
              370       380       390       400       410       420

         440       450       460       470       480       490     
pF1KE0 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR
       ::::::...:. :..:: ..:::::::::::: ::.::.::::...:: .::.::::..:
XP_005 RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
              430       440       450       460       470       480

         500       510       520       530       540       550     
pF1KE0 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW
       :::::::::::::  :.:  :...:::.: . :.: : :: ::::::.:.:: :::.:::
XP_005 FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
              490       500       510       520       530       540

         560       570       580       590       600       610     
pF1KE0 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAK
       ..:::::.:.::.. ::. ::.: . .:..                              
XP_005 FLALSSMVCVPLFVVITLLKTRGPFRKKVRD                             
              550       560       570                              




632 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:37:25 2016 done: Fri Nov  4 03:37:26 2016
 Total Scan time:  7.500 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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