Result of FASTA (omim) for
pF1KE0095
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0095, 1261 aa
1>>>pF1KE0095 1261 - 1261 aa - 1261 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6271+/-0.000467; mu= 13.1201+/- 0.029
mean_var=180.1553+/-37.632, 0's: 0 Z-trim(116.2): 131 B-trim: 2860 in 2/53
Lambda= 0.095554
statistics sampled from 27075 (27215) to 27075 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.319), width: 16
Scan time: 15.980
The best scores are: opt bits E(85289)
NP_899200 (OMIM: 600293,606703) adenylate cyclase (1261) 8381 1169.1 0
XP_005247134 (OMIM: 600293,606703) PREDICTED: aden (1286) 6523 913.0 0
NP_001186571 (OMIM: 600293,606703) adenylate cycla ( 911) 5862 821.7 0
NP_056085 (OMIM: 600294,616287) adenylate cyclase (1168) 5051 710.0 2.3e-203
XP_006719273 (OMIM: 600294,616287) PREDICTED: aden (1168) 5051 710.0 2.3e-203
XP_005247135 (OMIM: 600293,606703) PREDICTED: aden ( 936) 4004 565.6 5.4e-160
XP_016861127 (OMIM: 600293,606703) PREDICTED: aden ( 920) 4001 565.2 7.1e-160
XP_011510662 (OMIM: 600293,606703) PREDICTED: aden ( 923) 4000 565.1 7.8e-160
XP_006713546 (OMIM: 600293,606703) PREDICTED: aden ( 919) 3998 564.8 9.5e-160
XP_016861128 (OMIM: 600293,606703) PREDICTED: aden ( 920) 3998 564.8 9.5e-160
XP_011510661 (OMIM: 600293,606703) PREDICTED: aden ( 953) 3996 564.5 1.2e-159
XP_011510663 (OMIM: 600293,606703) PREDICTED: aden ( 845) 3581 507.3 1.8e-142
XP_016861129 (OMIM: 600293,606703) PREDICTED: aden ( 845) 3581 507.3 1.8e-142
XP_006713547 (OMIM: 600293,606703) PREDICTED: aden ( 845) 3581 507.3 1.8e-142
XP_016874232 (OMIM: 600294,616287) PREDICTED: aden (1067) 2669 381.6 1.5e-104
NP_001105 (OMIM: 600385) adenylate cyclase type 7 (1080) 1809 263.1 7.4e-69
XP_016878384 (OMIM: 600385) PREDICTED: adenylate c (1080) 1809 263.1 7.4e-69
NP_065433 (OMIM: 103071) adenylate cyclase type 2 (1091) 1767 257.3 4.1e-67
NP_001185497 (OMIM: 600292) adenylate cyclase type (1077) 1761 256.5 7.2e-67
NP_640340 (OMIM: 600292) adenylate cyclase type 4 (1077) 1761 256.5 7.2e-67
NP_001185521 (OMIM: 600292) adenylate cyclase type (1077) 1761 256.5 7.2e-67
XP_016878385 (OMIM: 600385) PREDICTED: adenylate c ( 886) 1703 248.4 1.6e-64
XP_016878386 (OMIM: 600385) PREDICTED: adenylate c ( 886) 1703 248.4 1.6e-64
XP_011521139 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
XP_011521141 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
XP_011521144 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
XP_011521138 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
XP_011521142 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
XP_011521137 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
XP_011521140 (OMIM: 600385) PREDICTED: adenylate c (1086) 1703 248.5 1.9e-64
NP_001106 (OMIM: 103070) adenylate cyclase type 8 (1251) 1601 234.5 3.5e-60
NP_004027 (OMIM: 600291) adenylate cyclase type 3 (1144) 1590 232.9 9.4e-60
NP_001307542 (OMIM: 600291) adenylate cyclase type (1145) 1589 232.8 1e-59
XP_005250826 (OMIM: 103070) PREDICTED: adenylate c (1221) 1586 232.4 1.4e-59
XP_016858682 (OMIM: 600291) PREDICTED: adenylate c ( 903) 1510 221.8 1.7e-56
XP_016858681 (OMIM: 600291) PREDICTED: adenylate c ( 904) 1509 221.7 1.8e-56
XP_016868496 (OMIM: 103070) PREDICTED: adenylate c ( 646) 1378 203.5 3.9e-51
XP_016868495 (OMIM: 103070) PREDICTED: adenylate c (1155) 1382 204.2 4.1e-51
XP_006716564 (OMIM: 103070) PREDICTED: adenylate c (1185) 1382 204.3 4.1e-51
XP_005249642 (OMIM: 103072,610154,610154) PREDICTE ( 563) 1325 196.1 5.6e-49
XP_005249641 (OMIM: 103072,610154,610154) PREDICTE ( 979) 1327 196.6 6.9e-49
NP_066939 (OMIM: 103072,610154,610154) adenylate c (1119) 1327 196.7 7.6e-49
XP_016858678 (OMIM: 600291) PREDICTED: adenylate c (1139) 1227 182.9 1.1e-44
XP_011530795 (OMIM: 600291) PREDICTED: adenylate c (1140) 1226 182.7 1.2e-44
NP_001268697 (OMIM: 103072,610154,610154) adenylat ( 338) 1179 175.8 4.4e-43
XP_016858679 (OMIM: 600291) PREDICTED: adenylate c (1098) 1074 161.8 2.4e-38
XP_016858676 (OMIM: 600291) PREDICTED: adenylate c (1163) 1062 160.1 7.8e-38
XP_011530793 (OMIM: 600291) PREDICTED: adenylate c (1164) 1062 160.1 7.8e-38
XP_011530796 (OMIM: 600291) PREDICTED: adenylate c (1120) 908 138.9 1.9e-31
XP_016858677 (OMIM: 600291) PREDICTED: adenylate c (1149) 908 138.9 1.9e-31
>>NP_899200 (OMIM: 600293,606703) adenylate cyclase type (1261 aa)
initn: 8381 init1: 8381 opt: 8381 Z-score: 6252.7 bits: 1169.1 E(85289): 0
Smith-Waterman score: 8381; 100.0% identity (100.0% similar) in 1261 aa overlap (1-1261:1-1261)
10 20 30 40 50 60
pF1KE0 MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 GAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 GEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 TIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 TIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 TITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 TITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 WPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 WPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 LVTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 LVTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 DKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 DKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL
1210 1220 1230 1240 1250 1260
pF1KE0 S
:
NP_899 S
>>XP_005247134 (OMIM: 600293,606703) PREDICTED: adenylat (1286 aa)
initn: 6523 init1: 6523 opt: 6523 Z-score: 4868.3 bits: 913.0 E(85289): 0
Smith-Waterman score: 8311; 98.1% identity (98.1% similar) in 1286 aa overlap (1-1261:1-1286)
10 20 30 40 50 60
pF1KE0 MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 TIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 TITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 WPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL
910 920 930 940 950 960
970 980 990
pF1KE0 LVTANAIDFFNNGTSQ---C----------------------PEHATKVALKVVTPIIIS
:::::::::::::::: : ::::::::::::::::::
XP_005 LVTANAIDFFNNGTSQWSLCENLRHRRMEAGTYFPSGVKEQSPEHATKVALKVVTPIIIS
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE0 VFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLAR
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KE0 ERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDR
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KE0 FRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQM
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KE0 KIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQL
1210 1220 1230 1240 1250 1260
1240 1250 1260
pF1KE0 ECRGVVKVKGKGEMMTYFLNGGPPLS
::::::::::::::::::::::::::
XP_005 ECRGVVKVKGKGEMMTYFLNGGPPLS
1270 1280
>>NP_001186571 (OMIM: 600293,606703) adenylate cyclase t (911 aa)
initn: 5858 init1: 5858 opt: 5862 Z-score: 4377.8 bits: 821.7 E(85289): 0
Smith-Waterman score: 5862; 98.4% identity (99.4% similar) in 898 aa overlap (364-1261:14-911)
340 350 360 370 380 390
pF1KE0 FFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVG
....:. .. ..:::::::::::::::
NP_001 MKSQKEGCCSRGDLSIQTGPGGEWAPRRLVSNVLIFSCTNIVG
10 20 30 40
400 410 420 430 440 450
pF1KE0 VCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQE
50 60 70 80 90 100
460 470 480 490 500 510
pF1KE0 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
110 120 130 140 150 160
520 530 540 550 560 570
pF1KE0 KILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
170 180 190 200 210 220
580 590 600 610 620 630
pF1KE0 VLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLK
230 240 250 260 270 280
640 650 660 670 680 690
pF1KE0 EHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEM
290 300 310 320 330 340
700 710 720 730 740 750
pF1KE0 KRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKY
350 360 370 380 390 400
760 770 780 790 800 810
pF1KE0 SKQVDDRFGAYVACASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKQVDDRFGAYVACASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCV
410 420 430 440 450 460
820 830 840 850 860 870
pF1KE0 KLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISA
470 480 490 500 510 520
880 890 900 910 920 930
pF1KE0 SQVNACHVAESAVNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVNACHVAESAVNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKL
530 540 550 560 570 580
940 950 960 970 980 990
pF1KE0 VLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFFNNGTSQCPEHATKVALKVVTPII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFFNNGTSQCPEHATKVALKVVTPII
590 600 610 620 630 640
1000 1010 1020 1030 1040 1050
pF1KE0 ISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFL
650 660 670 680 690 700
1060 1070 1080 1090 1100 1110
pF1KE0 ARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISE
710 720 730 740 750 760
1120 1130 1140 1150 1160 1170
pF1KE0 DRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNF
770 780 790 800 810 820
1180 1190 1200 1210 1220 1230
pF1KE0 QMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTY
830 840 850 860 870 880
1240 1250 1260
pF1KE0 QLECRGVVKVKGKGEMMTYFLNGGPPLS
::::::::::::::::::::::::::::
NP_001 QLECRGVVKVKGKGEMMTYFLNGGPPLS
890 900 910
>>NP_056085 (OMIM: 600294,616287) adenylate cyclase type (1168 aa)
initn: 4661 init1: 2353 opt: 5051 Z-score: 3772.2 bits: 710.0 E(85289): 2.3e-203
Smith-Waterman score: 5051; 68.0% identity (83.7% similar) in 1165 aa overlap (100-1258:16-1166)
70 80 90 100 110 120
pF1KE0 ASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRRGAASGGSTR
:.:: ::.:. .: .:::. .::
NP_056 MSWFSGLLVPKVDERKTAWGERNGQ-----KRSRRRGTRAGGFCT
10 20 30 40
130 140 150 160 170 180
pF1KE0 APPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEGGEGSGDGGS
. . . . .: : . .. . ::: . :: :: : . . .
NP_056 PRYMSCLRDAEPPSPTPAGPPRCPWQDDAFI--RRGGPGKGKELGLRAVALGFEDTEVTT
50 60 70 80 90
190 200 210 220 230 240
pF1KE0 SADSGSGAGPGAVLSLGACCLA-LLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAV
.: . . ..: :: : : :.:.:.::.: : :::::::::::..::::::.::::
NP_056 TAGGTAEVAPDAVPRSGRSCWRRLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAV
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 LVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGLACYALIAV
:::. :.:::::: : :.:.:: :..... . :.::: .:.:: : .. :.....
NP_056 LVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGI
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 VLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRT
. :::: : : .::: : :.: :::.: :::::.:::::::::. ::.::: .: .
NP_056 LAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQL
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 NAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQ
: : :: ::: .:::.: :::..:.:::::::::::::::::: :::::: :.::.::
NP_056 NRGDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQ
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE0 ERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQ
:::::::::.::::::: :::.:.::::::::::::::::::::::::::::::::::::
NP_056 ERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQ
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE0 ELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAI
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_056 ELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAI
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE0 SLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK
:::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::.
NP_056 SLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITR
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE0 ATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIG
:::.::::::::::: ::::::::::. ::::::: .:::::::::.::..: :.::.
NP_056 ATLQYLNGDYEVEPGRGGERNAYLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSME
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE0 HNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDP-KD-KNAQESANPEDEVDEFLGRAIDA
:.: .: : .. :: ...::..: :: ...:.. ::::::::::.:::::
NP_056 GLMPRWVPDRAFSR----TKDSKAFRQMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDA
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE0 RSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHS
::::.::..:::.:::::.. :::::::..:: ::::::::: ::: ::::.:. : :::
NP_056 RSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE0 IFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVF
.::..: . ::: ..:.. ..::: .:::. :: :::.::::. .:: ::.:.. :::
NP_056 TLMLGIYASIFLLLLITVLICAVYSCGSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVF
700 710 720 730 740 750
850 860 870 880 890 900
pF1KE0 LAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSPWPNCNF
.:..:::::: . .: :. :.. ....:::. . .::::: . .: . :.:.:
NP_056 TSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQ--LNYSLGLDAPLCEGTMPTCSF
760 770 780 790 800 810
910 920 930 940 950 960
pF1KE0 PEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIY-VLIVEVPGVTLFDNADLLVTAN
:::: ..:::::: ::::.:: ::::...... ::: ::.. : .:.::: :::. ..
NP_056 PEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVH
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KE0 AIDFFNNGTS--QCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQAT
.. :. . .:: : .:::: .::.:. ::.:::::::::::::::::::::::::
NP_056 GLASSNETFDGLDCPA-AGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQAT
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KE0 EEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KE0 YVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKV
::::::::::::::::::::::::::::::.:::::::::::::::::::::: ::::.:
NP_056 YVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQV
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KE0 GKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTV
:..:: ::::.::.::.:::.::::::::::::::::.::::::::::::::::::::::
NP_056 GRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTV
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KE0 NVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
::.:::::::::::::::::.::::::. ::::::::::::::::: ::::::::
NP_056 NVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
1120 1130 1140 1150 1160
>>XP_006719273 (OMIM: 600294,616287) PREDICTED: adenylat (1168 aa)
initn: 4661 init1: 2353 opt: 5051 Z-score: 3772.2 bits: 710.0 E(85289): 2.3e-203
Smith-Waterman score: 5051; 68.0% identity (83.7% similar) in 1165 aa overlap (100-1258:16-1166)
70 80 90 100 110 120
pF1KE0 ASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRRGAASGGSTR
:.:: ::.:. .: .:::. .::
XP_006 MSWFSGLLVPKVDERKTAWGERNGQ-----KRSRRRGTRAGGFCT
10 20 30 40
130 140 150 160 170 180
pF1KE0 APPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEGGEGSGDGGS
. . . . .: : . .. . ::: . :: :: : . . .
XP_006 PRYMSCLRDAEPPSPTPAGPPRCPWQDDAFI--RRGGPGKGKELGLRAVALGFEDTEVTT
50 60 70 80 90
190 200 210 220 230 240
pF1KE0 SADSGSGAGPGAVLSLGACCLA-LLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAV
.: . . ..: :: : : :.:.:.::.: : :::::::::::..::::::.::::
XP_006 TAGGTAEVAPDAVPRSGRSCWRRLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAV
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 LVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGLACYALIAV
:::. :.:::::: : :.:.:: :..... . :.::: .:.:: : .. :.....
XP_006 LVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGI
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 VLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRT
. :::: : : .::: : :.: :::.: :::::.:::::::::. ::.::: .: .
XP_006 LAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQL
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE0 NAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQ
: : :: ::: .:::.: :::..:.:::::::::::::::::: :::::: :.::.::
XP_006 NRGDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQ
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE0 ERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQ
:::::::::.::::::: :::.:.::::::::::::::::::::::::::::::::::::
XP_006 ERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQ
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE0 ELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAI
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_006 ELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAI
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE0 SLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK
:::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::.
XP_006 SLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITR
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE0 ATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIG
:::.::::::::::: ::::::::::. ::::::: .:::::::::.::..: :.::.
XP_006 ATLQYLNGDYEVEPGRGGERNAYLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSME
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE0 HNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDP-KD-KNAQESANPEDEVDEFLGRAIDA
:.: .: : .. :: ...::..: :: ...:.. ::::::::::.:::::
XP_006 GLMPRWVPDRAFSR----TKDSKAFRQMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDA
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE0 RSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHS
::::.::..:::.:::::.. :::::::..:: ::::::::: ::: ::::.:. : :::
XP_006 RSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE0 IFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVF
.::..: . ::: ..:.. ..::: .:::. :: :::.::::. .:: ::.:.. :::
XP_006 TLMLGIYASIFLLLLITVLICAVYSCGSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVF
700 710 720 730 740 750
850 860 870 880 890 900
pF1KE0 LAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSPWPNCNF
.:..:::::: . .: :. :.. ....:::. . .::::: . .: . :.:.:
XP_006 TSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQ--LNYSLGLDAPLCEGTMPTCSF
760 770 780 790 800 810
910 920 930 940 950 960
pF1KE0 PEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIY-VLIVEVPGVTLFDNADLLVTAN
:::: ..:::::: ::::.:: ::::...... ::: ::.. : .:.::: :::. ..
XP_006 PEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVH
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KE0 AIDFFNNGTS--QCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQAT
.. :. . .:: : .:::: .::.:. ::.:::::::::::::::::::::::::
XP_006 GLASSNETFDGLDCPA-AGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQAT
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KE0 EEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KE0 YVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKV
::::::::::::::::::::::::::::::.:::::::::::::::::::::: ::::.:
XP_006 YVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQV
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KE0 GKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTV
:..:: ::::.::.::.:::.::::::::::::::::.::::::::::::::::::::::
XP_006 GRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTV
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KE0 NVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
::.:::::::::::::::::.::::::. ::::::::::::::::: ::::::::
XP_006 NVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
1120 1130 1140 1150 1160
>>XP_005247135 (OMIM: 600293,606703) PREDICTED: adenylat (936 aa)
initn: 4000 init1: 4000 opt: 4004 Z-score: 2993.4 bits: 565.6 E(85289): 5.4e-160
Smith-Waterman score: 5792; 95.8% identity (96.7% similar) in 923 aa overlap (364-1261:14-936)
340 350 360 370 380 390
pF1KE0 FFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVG
....:. .. ..:::::::::::::::
XP_005 MKSQKEGCCSRGDLSIQTGPGGEWAPRRLVSNVLIFSCTNIVG
10 20 30 40
400 410 420 430 440 450
pF1KE0 VCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQE
50 60 70 80 90 100
460 470 480 490 500 510
pF1KE0 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
110 120 130 140 150 160
520 530 540 550 560 570
pF1KE0 KILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
170 180 190 200 210 220
580 590 600 610 620 630
pF1KE0 VLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLK
230 240 250 260 270 280
640 650 660 670 680 690
pF1KE0 EHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEM
290 300 310 320 330 340
700 710 720 730 740 750
pF1KE0 KRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKY
350 360 370 380 390 400
760 770 780 790 800 810
pF1KE0 SKQVDDRFGAYVACASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKQVDDRFGAYVACASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCV
410 420 430 440 450 460
820 830 840 850 860 870
pF1KE0 KLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISA
470 480 490 500 510 520
880 890 900 910 920 930
pF1KE0 SQVNACHVAESAVNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQVNACHVAESAVNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKL
530 540 550 560 570 580
940 950 960 970
pF1KE0 VLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFFNNGTSQ---C-------------
::::::::::::::::::::::::::::::::::::::::::: :
XP_005 VLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFFNNGTSQWSLCENLRHRRMEAGTY
590 600 610 620 630 640
980 990 1000 1010 1020
pF1KE0 ---------PEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSGVKEQSPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEE
650 660 670 680 690 700
1030 1040 1050 1060 1070 1080
pF1KE0 MEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELE
710 720 730 740 750 760
1090 1100 1110 1120 1130 1140
pF1KE0 ANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHI
770 780 790 800 810 820
1150 1160 1170 1180 1190 1200
pF1KE0 KALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASR
830 840 850 860 870 880
1210 1220 1230 1240 1250 1260
pF1KE0 MDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
890 900 910 920 930
>>XP_016861127 (OMIM: 600293,606703) PREDICTED: adenylat (920 aa)
initn: 3997 init1: 3997 opt: 4001 Z-score: 2991.2 bits: 565.2 E(85289): 7.1e-160
Smith-Waterman score: 5789; 96.0% identity (96.7% similar) in 923 aa overlap (364-1261:1-920)
340 350 360 370 380 390
pF1KE0 FFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVG
..:.:. . .: .:::::::::::::::
XP_016 MGLKTQWRHSF---RLVSNVLIFSCTNIVG
10 20
400 410 420 430 440 450
pF1KE0 VCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQE
30 40 50 60 70 80
460 470 480 490 500 510
pF1KE0 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
90 100 110 120 130 140
520 530 540 550 560 570
pF1KE0 KILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
150 160 170 180 190 200
580 590 600 610 620 630
pF1KE0 VLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLK
210 220 230 240 250 260
640 650 660 670 680 690
pF1KE0 EHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEM
270 280 290 300 310 320
700 710 720 730 740 750
pF1KE0 KRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKY
330 340 350 360 370 380
760 770 780 790 800 810
pF1KE0 SKQVDDRFGAYVACASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKQVDDRFGAYVACASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCV
390 400 410 420 430 440
820 830 840 850 860 870
pF1KE0 KLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLFPSPLQTLSRKIVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISA
450 460 470 480 490 500
880 890 900 910 920 930
pF1KE0 SQVNACHVAESAVNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVNACHVAESAVNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKL
510 520 530 540 550 560
940 950 960 970
pF1KE0 VLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFFNNGTSQ---C-------------
::::::::::::::::::::::::::::::::::::::::::: :
XP_016 VLMLAIELIYVLIVEVPGVTLFDNADLLVTANAIDFFNNGTSQWSLCENLRHRRMEAGTY
570 580 590 600 610 620
980 990 1000 1010 1020
pF1KE0 ---------PEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSGVKEQSPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEE
630 640 650 660 670 680
1030 1040 1050 1060 1070 1080
pF1KE0 MEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELE
690 700 710 720 730 740
1090 1100 1110 1120 1130 1140
pF1KE0 ANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHI
750 760 770 780 790 800
1150 1160 1170 1180 1190 1200
pF1KE0 KALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASR
810 820 830 840 850 860
1210 1220 1230 1240 1250 1260
pF1KE0 MDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
870 880 890 900 910 920
>>XP_011510662 (OMIM: 600293,606703) PREDICTED: adenylat (923 aa)
initn: 4000 init1: 4000 opt: 4000 Z-score: 2990.5 bits: 565.1 E(85289): 7.8e-160
Smith-Waterman score: 5788; 97.1% identity (97.1% similar) in 910 aa overlap (377-1261:14-923)
350 360 370 380 390 400
pF1KE0 MRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQ
: ::::::::::::::::::::::::::::
XP_011 MLLIRLRDFPSIPKLLVSNVLIFSCTNIVGVCTHYPAEVSQRQ
10 20 30 40
410 420 430 440 450 460
pF1KE0 AFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHD
50 60 70 80 90 100
470 480 490 500 510 520
pF1KE0 NVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGL
110 120 130 140 150 160
530 540 550 560 570 580
pF1KE0 PEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWS
170 180 190 200 210 220
590 600 610 620 630 640
pF1KE0 NDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCT
230 240 250 260 270 280
650 660 670 680 690 700
pF1KE0 QKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNA
290 300 310 320 330 340
710 720 730 740 750 760
pF1KE0 QESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVA
350 360 370 380 390 400
770 780 790 800 810 820
pF1KE0 CASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRK
410 420 430 440 450 460
830 840 850 860 870 880
pF1KE0 IVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAV
470 480 490 500 510 520
890 900 910 920 930 940
pF1KE0 NYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLI
530 540 550 560 570 580
950 960 970 980
pF1KE0 VEVPGVTLFDNADLLVTANAIDFFNNGTSQ---C----------------------PEHA
:::::::::::::::::::::::::::::: : ::::
XP_011 VEVPGVTLFDNADLLVTANAIDFFNNGTSQWSLCENLRHRRMEAGTYFPSGVKEQSPEHA
590 600 610 620 630 640
990 1000 1010 1020 1030 1040
pF1KE0 TKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLH
650 660 670 680 690 700
1050 1060 1070 1080 1090 1100
pF1KE0 NILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLN
710 720 730 740 750 760
1110 1120 1130 1140 1150 1160
pF1KE0 EIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQ
770 780 790 800 810 820
1170 1180 1190 1200 1210 1220
pF1KE0 MKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVT
830 840 850 860 870 880
1230 1240 1250 1260
pF1KE0 TDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
::::::::::::::::::::::::::::::::::::::::
XP_011 TDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
890 900 910 920
>>XP_006713546 (OMIM: 600293,606703) PREDICTED: adenylat (919 aa)
initn: 3998 init1: 3998 opt: 3998 Z-score: 2989.0 bits: 564.8 E(85289): 9.5e-160
Smith-Waterman score: 5786; 97.1% identity (97.2% similar) in 909 aa overlap (378-1261:11-919)
350 360 370 380 390 400
pF1KE0 RAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQA
.:::::::::::::::::::::::::::::
XP_006 MAPSRFRTQLELVSNVLIFSCTNIVGVCTHYPAEVSQRQA
10 20 30 40
410 420 430 440 450 460
pF1KE0 FQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDN
50 60 70 80 90 100
470 480 490 500 510 520
pF1KE0 VSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLP
110 120 130 140 150 160
530 540 550 560 570 580
pF1KE0 EARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSN
170 180 190 200 210 220
590 600 610 620 630 640
pF1KE0 DVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQ
230 240 250 260 270 280
650 660 670 680 690 700
pF1KE0 KRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQ
290 300 310 320 330 340
710 720 730 740 750 760
pF1KE0 ESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVAC
350 360 370 380 390 400
770 780 790 800 810 820
pF1KE0 ASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKI
410 420 430 440 450 460
830 840 850 860 870 880
pF1KE0 VRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVN
470 480 490 500 510 520
890 900 910 920 930 940
pF1KE0 YSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIV
530 540 550 560 570 580
950 960 970 980
pF1KE0 EVPGVTLFDNADLLVTANAIDFFNNGTSQ---C----------------------PEHAT
::::::::::::::::::::::::::::: : :::::
XP_006 EVPGVTLFDNADLLVTANAIDFFNNGTSQWSLCENLRHRRMEAGTYFPSGVKEQSPEHAT
590 600 610 620 630 640
990 1000 1010 1020 1030 1040
pF1KE0 KVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHN
650 660 670 680 690 700
1050 1060 1070 1080 1090 1100
pF1KE0 ILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNE
710 720 730 740 750 760
1110 1120 1130 1140 1150 1160
pF1KE0 IIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQM
770 780 790 800 810 820
1170 1180 1190 1200 1210 1220
pF1KE0 KYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTT
830 840 850 860 870 880
1230 1240 1250 1260
pF1KE0 DMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
:::::::::::::::::::::::::::::::::::::::
XP_006 DMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
890 900 910
>>XP_016861128 (OMIM: 600293,606703) PREDICTED: adenylat (920 aa)
initn: 3998 init1: 3998 opt: 3998 Z-score: 2989.0 bits: 564.8 E(85289): 9.5e-160
Smith-Waterman score: 5786; 97.1% identity (97.2% similar) in 909 aa overlap (378-1261:12-920)
350 360 370 380 390 400
pF1KE0 RAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQA
.:::::::::::::::::::::::::::::
XP_016 MQTSACCPEWAKLVSNVLIFSCTNIVGVCTHYPAEVSQRQA
10 20 30 40
410 420 430 440 450 460
pF1KE0 FQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDN
50 60 70 80 90 100
470 480 490 500 510 520
pF1KE0 VSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLP
110 120 130 140 150 160
530 540 550 560 570 580
pF1KE0 EARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSN
170 180 190 200 210 220
590 600 610 620 630 640
pF1KE0 DVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQ
230 240 250 260 270 280
650 660 670 680 690 700
pF1KE0 KRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQ
290 300 310 320 330 340
710 720 730 740 750 760
pF1KE0 ESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVAC
350 360 370 380 390 400
770 780 790 800 810 820
pF1KE0 ASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLVFLFICFVQITIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKI
410 420 430 440 450 460
830 840 850 860 870 880
pF1KE0 VRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRSKMNSTLVGVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVN
470 480 490 500 510 520
890 900 910 920 930 940
pF1KE0 YSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIV
530 540 550 560 570 580
950 960 970 980
pF1KE0 EVPGVTLFDNADLLVTANAIDFFNNGTSQ---C----------------------PEHAT
::::::::::::::::::::::::::::: : :::::
XP_016 EVPGVTLFDNADLLVTANAIDFFNNGTSQWSLCENLRHRRMEAGTYFPSGVKEQSPEHAT
590 600 610 620 630 640
990 1000 1010 1020 1030 1040
pF1KE0 KVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHN
650 660 670 680 690 700
1050 1060 1070 1080 1090 1100
pF1KE0 ILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNE
710 720 730 740 750 760
1110 1120 1130 1140 1150 1160
pF1KE0 IIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQM
770 780 790 800 810 820
1170 1180 1190 1200 1210 1220
pF1KE0 KYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTT
830 840 850 860 870 880
1230 1240 1250 1260
pF1KE0 DMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
:::::::::::::::::::::::::::::::::::::::
XP_016 DMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
890 900 910 920
1261 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:27:41 2016 done: Fri Nov 4 03:27:43 2016
Total Scan time: 15.980 Total Display time: 0.440
Function used was FASTA [36.3.4 Apr, 2011]