FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0096, 1835 aa 1>>>pF1KE0096 1835 - 1835 aa - 1835 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.0452+/-0.000597; mu= -22.5240+/- 0.037 mean_var=616.3857+/-130.053, 0's: 0 Z-trim(119.0): 140 B-trim: 0 in 0/58 Lambda= 0.051659 statistics sampled from 32454 (32592) to 32454 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.382), width: 16 Scan time: 21.720 The best scores are: opt bits E(85289) NP_689854 (OMIM: 609539) AT-rich interactive domai (1835) 12195 926.0 0 XP_006719335 (OMIM: 609539) PREDICTED: AT-rich int (1793) 11908 904.6 0 XP_011536327 (OMIM: 609539) PREDICTED: AT-rich int (1291) 8561 655.1 1.3e-186 >>NP_689854 (OMIM: 609539) AT-rich interactive domain-co (1835 aa) initn: 12195 init1: 12195 opt: 12195 Z-score: 4933.0 bits: 926.0 E(85289): 0 Smith-Waterman score: 12195; 100.0% identity (100.0% similar) in 1835 aa overlap (1-1835:1-1835) 10 20 30 40 50 60 pF1KE0 MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 AKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSTVFGEEWKEKTDRDFVKFWKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 TLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSTVFGEEWKEKTDRDFVKFWKDI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VDDNEVRDLISDRNKSHEGTSGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 VDDNEVRDLISDRNKSHEGTSGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 GNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVISTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 KCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVISTLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 VLYMLTEMGDVACTKIAKVEKSIDMLVCLVSMDIQMFGPDALAAVKLIEHPSSSHQMLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 VLYMLTEMGDVACTKIAKVEKSIDMLVCLVSMDIQMFGPDALAAVKLIEHPSSSHQMLSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 IRPQAIEQVQTQTHVASAPASRAVVAQHVAPPPGIVEIDSEKFACQWLNAHFEVNPDCSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 IRPQAIEQVQTQTHVASAPASRAVVAQHVAPPPGIVEIDSEKFACQWLNAHFEVNPDCSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 SRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSSSNGQAHIHVVGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 SRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSSSNGQAHIHVVGVK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RRAIPLPIQMYYQQQPVSTSVVRVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPVANQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 RRAIPLPIQMYYQQQPVSTSVVRVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPVANQSS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 NLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQQQNAPVTVIQSKAPIPCEVVKATVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 NLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQQQNAPVTVIQSKAPIPCEVVKATVIQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 NSIPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 NSIPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 GQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 GQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 QSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGVPSPQASRVGFQNIAPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGVPSPQASRVGFQNIAPKP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 LPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALPAGQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALPAGQTV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 QLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQQQHSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQQQHSPA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 PPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPASGESSLIKQLLLPKRGPSTPGGKLILP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 PPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPASGESSLIKQLLLPKRGPSTPGGKLILP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 APQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQLLVGQQNVQLVPSAMPPSGGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 APQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQLLVGQQNVQLVPSAMPPSGGV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 QTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFAPATVSQGNATQLIAPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFAPATVSQGNATQLIAPAG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 ITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATPPFKGDKIICQKEEEAKEATGLHVHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 ITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATPPFKGDKIICQKEEEAKEATGLHVHE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 RKIEVMENPSCRRGATNTSNGDTKENEMHVGSLLNGRKYSDSSLPPSNSGKIQSETNQCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 RKIEVMENPSCRRGATNTSNGDTKENEMHVGSLLNGRKYSDSSLPPSNSGKIQSETNQCS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 LISNGPSLELGENGASGKQNSEQIDMQDIKSDLRKPLVNGICDFDKGDGSHLSKNIPNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LISNGPSLELGENGASGKQNSEQIDMQDIKSDLRKPLVNGICDFDKGDGSHLSKNIPNHK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE0 TSNHVGNGEISPMEPQGTLDITQQDTAKGDQLERISNGPVLTLGGSSVSSIQEASNAATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 TSNHVGNGEISPMEPQGTLDITQQDTAKGDQLERISNGPVLTLGGSSVSSIQEASNAATQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE0 QFSGTDLLNGPLASSLNSDVPQQRPSVVVSPHSTTSVIQGHQIIAVPDSGSKVSHSPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 QFSGTDLLNGPLASSLNSDVPQQRPSVVVSPHSTTSVIQGHQIIAVPDSGSKVSHSPALS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE0 SDVRSTNGTAECKTVKRPAEDTDRETVAGIPNKVGVRIVTISDPNNAGCSATMVAVPAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 SDVRSTNGTAECKTVKRPAEDTDRETVAGIPNKVGVRIVTISDPNNAGCSATMVAVPAGA 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE0 DPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTPMPPSPAVQVQGQPNSSQPSPFSGSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 DPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTPMPPSPAVQVQGQPNSSQPSPFSGSSQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE0 PGDPMRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 PGDPMRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE0 SFITHLQDKHCSKDALLAGLKQDEPGQAGSQKSSTKQPTVGGTSSTPRAQKAIVNHPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 SFITHLQDKHCSKDALLAGLKQDEPGQAGSQKSSTKQPTVGGTSSTPRAQKAIVNHPSAA 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE0 LMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVL 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KE0 AISNMEASSTLAKCLYELNFTVQSKEQEKDSEMLQ ::::::::::::::::::::::::::::::::::: NP_689 AISNMEASSTLAKCLYELNFTVQSKEQEKDSEMLQ 1810 1820 1830 >>XP_006719335 (OMIM: 609539) PREDICTED: AT-rich interac (1793 aa) initn: 11908 init1: 11908 opt: 11908 Z-score: 4817.5 bits: 904.6 E(85289): 0 Smith-Waterman score: 11908; 100.0% identity (100.0% similar) in 1788 aa overlap (1-1788:1-1788) 10 20 30 40 50 60 pF1KE0 MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 QLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 TLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSTVFGEEWKEKTDRDFVKFWKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSTVFGEEWKEKTDRDFVKFWKDI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 VDDNEVRDLISDRNKSHEGTSGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDDNEVRDLISDRNKSHEGTSGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 GNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFKTTHLMFHTVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 KCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVISTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVISTLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 VLYMLTEMGDVACTKIAKVEKSIDMLVCLVSMDIQMFGPDALAAVKLIEHPSSSHQMLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLYMLTEMGDVACTKIAKVEKSIDMLVCLVSMDIQMFGPDALAAVKLIEHPSSSHQMLSE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 IRPQAIEQVQTQTHVASAPASRAVVAQHVAPPPGIVEIDSEKFACQWLNAHFEVNPDCSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRPQAIEQVQTQTHVASAPASRAVVAQHVAPPPGIVEIDSEKFACQWLNAHFEVNPDCSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 SRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSSSNGQAHIHVVGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSSSNGQAHIHVVGVK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 RRAIPLPIQMYYQQQPVSTSVVRVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPVANQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRAIPLPIQMYYQQQPVSTSVVRVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPVANQSS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 NLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQQQNAPVTVIQSKAPIPCEVVKATVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQQQNAPVTVIQSKAPIPCEVVKATVIQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 NSIPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSIPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE0 GQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE0 QSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGVPSPQASRVGFQNIAPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGVPSPQASRVGFQNIAPKP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE0 LPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALPAGQTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALPAGQTV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE0 QLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQQQHSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQQQHSPA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE0 PPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPASGESSLIKQLLLPKRGPSTPGGKLILP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPASGESSLIKQLLLPKRGPSTPGGKLILP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE0 APQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQLLVGQQNVQLVPSAMPPSGGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQLLVGQQNVQLVPSAMPPSGGV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE0 QTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFAPATVSQGNATQLIAPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFAPATVSQGNATQLIAPAG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE0 ITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATPPFKGDKIICQKEEEAKEATGLHVHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATPPFKGDKIICQKEEEAKEATGLHVHE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE0 RKIEVMENPSCRRGATNTSNGDTKENEMHVGSLLNGRKYSDSSLPPSNSGKIQSETNQCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKIEVMENPSCRRGATNTSNGDTKENEMHVGSLLNGRKYSDSSLPPSNSGKIQSETNQCS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE0 LISNGPSLELGENGASGKQNSEQIDMQDIKSDLRKPLVNGICDFDKGDGSHLSKNIPNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LISNGPSLELGENGASGKQNSEQIDMQDIKSDLRKPLVNGICDFDKGDGSHLSKNIPNHK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE0 TSNHVGNGEISPMEPQGTLDITQQDTAKGDQLERISNGPVLTLGGSSVSSIQEASNAATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSNHVGNGEISPMEPQGTLDITQQDTAKGDQLERISNGPVLTLGGSSVSSIQEASNAATQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE0 QFSGTDLLNGPLASSLNSDVPQQRPSVVVSPHSTTSVIQGHQIIAVPDSGSKVSHSPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QFSGTDLLNGPLASSLNSDVPQQRPSVVVSPHSTTSVIQGHQIIAVPDSGSKVSHSPALS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE0 SDVRSTNGTAECKTVKRPAEDTDRETVAGIPNKVGVRIVTISDPNNAGCSATMVAVPAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDVRSTNGTAECKTVKRPAEDTDRETVAGIPNKVGVRIVTISDPNNAGCSATMVAVPAGA 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE0 DPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTPMPPSPAVQVQGQPNSSQPSPFSGSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTPMPPSPAVQVQGQPNSSQPSPFSGSSQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE0 PGDPMRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGDPMRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE0 SFITHLQDKHCSKDALLAGLKQDEPGQAGSQKSSTKQPTVGGTSSTPRAQKAIVNHPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SFITHLQDKHCSKDALLAGLKQDEPGQAGSQKSSTKQPTVGGTSSTPRAQKAIVNHPSAA 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE0 LMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVL :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRNMNED 1750 1760 1770 1780 1790 1810 1820 1830 pF1KE0 AISNMEASSTLAKCLYELNFTVQSKEQEKDSEMLQ >>XP_011536327 (OMIM: 609539) PREDICTED: AT-rich interac (1291 aa) initn: 8561 init1: 8561 opt: 8561 Z-score: 3471.4 bits: 655.1 E(85289): 1.3e-186 Smith-Waterman score: 8561; 100.0% identity (100.0% similar) in 1291 aa overlap (545-1835:1-1291) 520 530 540 550 560 570 pF1KE0 IVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTV :::::::::::::::::::::::::::::: XP_011 MYSEYLSTCSKLARGGILTSTGFYKCLRTV 10 20 30 580 590 600 610 620 630 pF1KE0 FPNHTVKRVEDSSSNGQAHIHVVGVKRRAIPLPIQMYYQQQPVSTSVVRVDSVPDVSPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPNHTVKRVEDSSSNGQAHIHVVGVKRRAIPLPIQMYYQQQPVSTSVVRVDSVPDVSPAP 40 50 60 70 80 90 640 650 660 670 680 690 pF1KE0 SPAGIPHGSQTIGNHFQRTPVANQSSNLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPAGIPHGSQTIGNHFQRTPVANQSSNLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQ 100 110 120 130 140 150 700 710 720 730 740 750 pF1KE0 QQNAPVTVIQSKAPIPCEVVKATVIQNSIPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQNAPVTVIQSKAPIPCEVVKATVIQNSIPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPV 160 170 180 190 200 210 760 770 780 790 800 810 pF1KE0 TVVNSQTLLHHPSVIPQQSPLHTVVPGQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVNSQTLLHHPSVIPQQSPLHTVVPGQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTST 220 230 240 250 260 270 820 830 840 850 860 870 pF1KE0 VSQGQQLITTSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNIVSATSVQNFQVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSQGQQLITTSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNIVSATSVQNFQVAT 280 290 300 310 320 330 880 890 900 910 920 930 pF1KE0 GQMVTIAGVPSPQASRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQMVTIAGVPSPQASRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQ 340 350 360 370 380 390 940 950 960 970 980 990 pF1KE0 QGQTYAPAIHQIVLANPAALPAGQTVQLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGQTYAPAIHQIVLANPAALPAGQTVQLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTP 400 410 420 430 440 450 1000 1010 1020 1030 1040 1050 pF1KE0 QSQGPPPTVSQMLSVKRQQQQQHSPAPPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSQGPPPTVSQMLSVKRQQQQQHSPAPPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPAS 460 470 480 490 500 510 1060 1070 1080 1090 1100 1110 pF1KE0 GESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQ 520 530 540 550 560 570 1120 1130 1140 1150 1160 1170 pF1KE0 TPAQQLLVGQQNVQLVPSAMPPSGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPAQQLLVGQQNVQLVPSAMPPSGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTI 580 590 600 610 620 630 1180 1190 1200 1210 1220 1230 pF1KE0 TVVPNTSFAPATVSQGNATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQSSCTTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVPNTSFAPATVSQGNATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQSSCTTAT 640 650 660 670 680 690 1240 1250 1260 1270 1280 1290 pF1KE0 PPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGATNTSNGDTKENEMHVGSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGATNTSNGDTKENEMHVGSLL 700 710 720 730 740 750 1300 1310 1320 1330 1340 1350 pF1KE0 NGRKYSDSSLPPSNSGKIQSETNQCSLISNGPSLELGENGASGKQNSEQIDMQDIKSDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGRKYSDSSLPPSNSGKIQSETNQCSLISNGPSLELGENGASGKQNSEQIDMQDIKSDLR 760 770 780 790 800 810 1360 1370 1380 1390 1400 1410 pF1KE0 KPLVNGICDFDKGDGSHLSKNIPNHKTSNHVGNGEISPMEPQGTLDITQQDTAKGDQLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPLVNGICDFDKGDGSHLSKNIPNHKTSNHVGNGEISPMEPQGTLDITQQDTAKGDQLER 820 830 840 850 860 870 1420 1430 1440 1450 1460 1470 pF1KE0 ISNGPVLTLGGSSVSSIQEASNAATQQFSGTDLLNGPLASSLNSDVPQQRPSVVVSPHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISNGPVLTLGGSSVSSIQEASNAATQQFSGTDLLNGPLASSLNSDVPQQRPSVVVSPHST 880 890 900 910 920 930 1480 1490 1500 1510 1520 1530 pF1KE0 TSVIQGHQIIAVPDSGSKVSHSPALSSDVRSTNGTAECKTVKRPAEDTDRETVAGIPNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVIQGHQIIAVPDSGSKVSHSPALSSDVRSTNGTAECKTVKRPAEDTDRETVAGIPNKV 940 950 960 970 980 990 1540 1550 1560 1570 1580 1590 pF1KE0 GVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAVQQKQQHPPTYVQNVVPQNTP 1000 1010 1020 1030 1040 1050 1600 1610 1620 1630 1640 1650 pF1KE0 MPPSPAVQVQGQPNSSQPSPFSGSSQPGDPMRKPGQNFMCLWQSCKKWFQTPSQVFYHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPPSPAVQVQGQPNSSQPSPFSGSSQPGDPMRKPGQNFMCLWQSCKKWFQTPSQVFYHAA 1060 1070 1080 1090 1100 1110 1660 1670 1680 1690 1700 1710 pF1KE0 TEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQAGSQKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQAGSQKSS 1120 1130 1140 1150 1160 1170 1720 1730 1740 1750 1760 1770 pF1KE0 TKQPTVGGTSSTPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKQPTVGGTSSTPRAQKAIVNHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAAL 1180 1190 1200 1210 1220 1230 1780 1790 1800 1810 1820 1830 pF1KE0 ILKNIGKYSECGRRLLKRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEKDSEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILKNIGKYSECGRRLLKRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEKDSEML 1240 1250 1260 1270 1280 1290 pF1KE0 Q : XP_011 Q 1835 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:24:53 2016 done: Fri Nov 4 03:24:56 2016 Total Scan time: 21.720 Total Display time: 0.300 Function used was FASTA [36.3.4 Apr, 2011]