FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE0100, 832 aa 1>>>pF1KE0100 832 - 832 aa - 832 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5439+/-0.00105; mu= 9.8826+/- 0.064 mean_var=268.5375+/-53.926, 0's: 0 Z-trim(113.7): 49 B-trim: 11 in 1/50 Lambda= 0.078266 statistics sampled from 14256 (14299) to 14256 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.439), width: 16 Scan time: 4.660 The best scores are: opt bits E(32554) CCDS2634.1 KAT2B gene_id:8850|Hs108|chr3 ( 832) 5601 646.2 6.5e-185 CCDS11417.1 KAT2A gene_id:2648|Hs108|chr17 ( 837) 3941 458.8 1.7e-128 >>CCDS2634.1 KAT2B gene_id:8850|Hs108|chr3 (832 aa) initn: 5601 init1: 5601 opt: 5601 Z-score: 3433.3 bits: 646.2 E(32554): 6.5e-185 Smith-Waterman score: 5601; 100.0% identity (100.0% similar) in 832 aa overlap (1-832:1-832) 10 20 30 40 50 60 pF1KE0 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE0 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE0 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE0 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE0 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE0 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE0 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE0 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE0 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE0 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE0 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE0 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE0 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR 730 740 750 760 770 780 790 800 810 820 830 pF1KE0 YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS26 YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 790 800 810 820 830 >>CCDS11417.1 KAT2A gene_id:2648|Hs108|chr17 (837 aa) initn: 3534 init1: 2373 opt: 3941 Z-score: 2420.2 bits: 458.8 E(32554): 1.7e-128 Smith-Waterman score: 3941; 71.6% identity (86.4% similar) in 821 aa overlap (22-832:26-837) 10 20 30 40 50 pF1KE0 MSEAGGAGPGGCGAGAGAGAGPGALP-PQPAALP-PAP---PQGSPCAAAAGGSGA : : :.::. : :.: : .: :: ::..:. CCDS11 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 10 20 30 40 50 60 60 70 80 90 100 pF1KE0 CGPATAVAAAGTAEGPGGGG---SARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKC ::... ..::.. :. : . : . .:::.:. :::::::::::.:::::.:.::: CCDS11 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE0 NGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDV ::::::.: :: :: :::: ..:.: :::: : :: ::::::::::.:.:::::.:.:: CCDS11 NGWKNPKP-PTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDV 130 140 150 160 170 170 180 190 200 210 220 pF1KE0 EYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNF : :: ::::::.::::::::::::::: ::: .::::::: .::::::.::::: :: CCDS11 ENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNF 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE0 VQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCY :::::::: .::::. ::.:::: .:::.::.:.: : :: .:.. :: :::::::: CCDS11 VQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCY 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE0 CNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPK :.::: ::::::::::.::::.::::.::: ::::::. : ::::: :::::::::::: CCDS11 CHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPK 300 310 320 330 340 350 350 360 370 380 390 400 pF1KE0 FLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN- ::::::::.:. :::::.. : :. : : : : :.... :. . .:. CCDS11 FLSMLEEEIYGANSPIWESGFTMPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KE0 -AGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAA .::.: :.: : ::::: . .. .::.::. ::::::::::.:::: ::::::: CCDS11 GGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAA 420 430 440 450 460 470 470 480 490 500 510 520 pF1KE0 MLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQL ::::::..:::..::::.::::::::.:::::.::::. : :...:.::::::::::::: CCDS11 MLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KE0 PRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYG ::::::::.:::::::::::::::::::::::::::::.::::::::::::::::::::: CCDS11 PRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYG 540 550 560 570 580 590 590 600 610 620 630 640 pF1KE0 THLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLM ::::::::::::::.:: ::::::::::::::::::::.::.::..:.:::::::::::: CCDS11 THLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLM 600 610 620 630 640 650 650 660 670 680 690 700 pF1KE0 GCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGI :::::::::::.: :::::::::::::::::::::::::::::::.::::::.::.::: CCDS11 ECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGI 660 670 680 690 700 710 710 720 730 740 750 760 pF1KE0 RETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRF ::::::: ::::.:: .::::::.:::..: :.::: ::::::::::..::: ::::::: CCDS11 RETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRF 720 730 740 750 760 770 770 780 790 800 810 820 pF1KE0 PMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE :.:::::.:::..::::..:::.::::::..::.:::::.::: .::. :::::. :.:: CCDS11 PIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 780 790 800 810 820 830 830 pF1KE0 AGLIDK .::::: CCDS11 GGLIDK 832 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:01:19 2016 done: Sat Nov 5 07:01:20 2016 Total Scan time: 4.660 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]